ATE102186T1 - Piperidinderivate, verfahren zur herstellung sowie diese enthaltende pharmazeutische praeparate. - Google Patents

Piperidinderivate, verfahren zur herstellung sowie diese enthaltende pharmazeutische praeparate.

Info

Publication number: ATE102186T1
Authority: AT; Austria
Prior art keywords: image; pathology; piperide; individuals; manufacture
Prior art date: 1989-12-12

Application number

AT90403537T

Other languages

English (en)

Inventor

Gilbert Regnier

Plessis

De La Faverie J F Renaud

Alain Lombet

Jean-Pierre Iliou

Jean-Paul Vilaine

Jean-Pierre Bidouard

Albert Lenaers

Original Assignee

Adir

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-12-12

Filing date

1990-12-12

Publication date

1994-03-15

1990-12-12 Application filed by Adir filed Critical Adir

1994-03-15 Application granted granted Critical

1994-03-15 Publication of ATE102186T1 publication Critical patent/ATE102186T1/de

Links

238000004519 manufacturing process Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
239000005864 Sulphur Substances 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
239000003814 drug Substances 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
229910052760 oxygen Inorganic materials 0.000 abstract 2
239000001301 oxygen Substances 0.000 abstract 2
230000007170 pathology Effects 0.000 abstract 2
125000001424 substituent group Chemical group 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
230000000977 initiatory effect Effects 0.000 abstract 1
208000028867 ischemia Diseases 0.000 abstract 1
230000003859 lipid peroxidation Effects 0.000 abstract 1
230000002093 peripheral effect Effects 0.000 abstract 1
150000003053 piperidines Chemical class 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000006439 vascular pathology Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/54—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)

AT90403537T 1989-12-12 1990-12-12 Piperidinderivate, verfahren zur herstellung sowie diese enthaltende pharmazeutische praeparate. ATE102186T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8916384A FR2655649B1 (fr)	1989-12-12	1989-12-12	Nouveaux derives de la piperidine, leur procede de preparation et les compositions pharmaceutiques les renfermant.
EP90403537A EP0433167B1 (de)	1989-12-12	1990-12-12	Piperidinderivate, Verfahren zur Herstellung sowie diese enthaltende pharmazeutische Präparate

Publications (1)

Publication Number	Publication Date
ATE102186T1 true ATE102186T1 (de)	1994-03-15

Family

ID=9388394

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90403537T ATE102186T1 (de)	1989-12-12	1990-12-12	Piperidinderivate, verfahren zur herstellung sowie diese enthaltende pharmazeutische praeparate.

Country Status (15)

Country	Link
US (1)	US5126356A (de)
EP (1)	EP0433167B1 (de)
JP (1)	JPH07100695B2 (de)
AT (1)	ATE102186T1 (de)
AU (1)	AU629076B2 (de)
CA (1)	CA2031839A1 (de)
DE (1)	DE69007045T2 (de)
DK (1)	DK0433167T3 (de)
ES (1)	ES2052217T3 (de)
FR (1)	FR2655649B1 (de)
IE (1)	IE66909B1 (de)
NZ (1)	NZ236231A (de)
OA (1)	OA09473A (de)
PT (1)	PT96156B (de)
ZA (1)	ZA909768B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU214331B (hu) *	1992-06-17	1998-03-02	Gyógyszerkutató Intézet Kft.	Eljárás piperazin- és homopiperazinszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására
AU2003235095A1 (en) *	2002-05-28	2003-12-12	Nippon Chemiphar Co., Ltd.	Piperidine derivatives
WO2005030721A1 (ja) *	2003-09-30	2005-04-07	Nippon Chemiphar Co., Ltd.	ピペリジン誘導体
TWI759267B (zh)	2015-07-02	2022-04-01	美商地平線罕見醫學製藥有限責任公司	Ａｄｏ抗性半胱胺類似物及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB780027A (en) *	1955-01-20	1957-07-31	Schering Corp	3-piperidyl ethers and thioethers
FR2514353A2 (fr) *	1980-04-28	1983-04-15	Synthelabo	Derives de piperidine et leur application en therapeutique
EP0077427B1 (de) *	1981-10-15	1985-05-22	Synthelabo	Piperidin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US4529730A (en) *	1981-10-21	1985-07-16	Synthelabo	Piperidine derivatives, their preparation and pharmaceutical compositions containing them
GB8321157D0 (en) *	1983-08-05	1983-09-07	Fordonal Sa	Piperidine derivatives
ZA848275B (en) *	1983-12-28	1985-08-28	Degussa	New piridine-2-ethers or pyridine-2-thioethers having a nitrogen-containing cycloaliphatic ring

1989
- 1989-12-12 FR FR8916384A patent/FR2655649B1/fr not_active Expired - Fee Related
1990
- 1990-11-27 NZ NZ236231A patent/NZ236231A/en unknown
- 1990-12-05 ZA ZA909768A patent/ZA909768B/xx unknown
- 1990-12-07 CA CA002031839A patent/CA2031839A1/fr not_active Abandoned
- 1990-12-10 IE IE443490A patent/IE66909B1/en not_active IP Right Cessation
- 1990-12-11 AU AU67936/90A patent/AU629076B2/en not_active Ceased
- 1990-12-11 PT PT96156A patent/PT96156B/pt not_active IP Right Cessation
- 1990-12-11 US US07/625,422 patent/US5126356A/en not_active Expired - Fee Related
- 1990-12-12 ES ES90403537T patent/ES2052217T3/es not_active Expired - Lifetime
- 1990-12-12 OA OA59915A patent/OA09473A/xx unknown
- 1990-12-12 EP EP90403537A patent/EP0433167B1/de not_active Expired - Lifetime
- 1990-12-12 JP JP2419227A patent/JPH07100695B2/ja not_active Expired - Lifetime
- 1990-12-12 DE DE69007045T patent/DE69007045T2/de not_active Expired - Fee Related
- 1990-12-12 DK DK90403537.5T patent/DK0433167T3/da active
- 1990-12-12 AT AT90403537T patent/ATE102186T1/de active

Also Published As

Publication number	Publication date
DE69007045T2 (de)	1994-08-04
FR2655649A1 (fr)	1991-06-14
OA09473A (fr)	1992-11-15
IE66909B1 (en)	1996-02-07
US5126356A (en)	1992-06-30
IE904434A1 (en)	1991-06-19
JPH06340626A (ja)	1994-12-13
FR2655649B1 (fr)	1994-07-08
CA2031839A1 (fr)	1991-06-13
AU629076B2 (en)	1992-09-24
EP0433167A1 (de)	1991-06-19
ZA909768B (en)	1991-09-25
AU6793690A (en)	1991-06-20
NZ236231A (en)	1992-07-28
JPH07100695B2 (ja)	1995-11-01
ES2052217T3 (es)	1994-07-01
DK0433167T3 (da)	1994-05-02
PT96156A (pt)	1991-09-30
EP0433167B1 (de)	1994-03-02
DE69007045D1 (de)	1994-04-07
PT96156B (pt)	1998-05-29

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