ATE103002T1 - Menschlicher monoklonaler antikoerper gegen lymphadenopathie assozierten virus. - Google Patents

Menschlicher monoklonaler antikoerper gegen lymphadenopathie assozierten virus.

Info

Publication number
ATE103002T1
ATE103002T1 AT87305505T AT87305505T ATE103002T1 AT E103002 T1 ATE103002 T1 AT E103002T1 AT 87305505 T AT87305505 T AT 87305505T AT 87305505 T AT87305505 T AT 87305505T AT E103002 T1 ATE103002 T1 AT E103002T1
Authority
AT
Austria
Prior art keywords
monoclonal antibodies
human monoclonal
lav
htlv
iii
Prior art date
Application number
AT87305505T
Other languages
English (en)
Inventor
Janela Mcclure
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ATE103002T1 publication Critical patent/ATE103002T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/112—Retroviridae (F), e.g. leukemia viruses
    • C07K16/114—Lentivirus (G), e.g. human immunodeficiency virus [HIV], feline immunodeficiency virus [FIV] or simian immunodeficiency virus [SIV]
    • C07K16/1145—Env proteins, e.g. gp41, gp110/120, gp160, V3, principal neutralising domain [PND] or CD4-binding site
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT87305505T 1986-06-23 1987-06-22 Menschlicher monoklonaler antikoerper gegen lymphadenopathie assozierten virus. ATE103002T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87757986A 1986-06-23 1986-06-23
EP87305505A EP0251612B1 (de) 1986-06-23 1987-06-22 Menschlicher monoklonaler Antikörper gegen Lymphadenopathie assozierten Virus

Publications (1)

Publication Number Publication Date
ATE103002T1 true ATE103002T1 (de) 1994-04-15

Family

ID=25370267

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87305505T ATE103002T1 (de) 1986-06-23 1987-06-22 Menschlicher monoklonaler antikoerper gegen lymphadenopathie assozierten virus.

Country Status (12)

Country Link
EP (1) EP0251612B1 (de)
JP (1) JP2626680B2 (de)
KR (1) KR910001808B1 (de)
AT (1) ATE103002T1 (de)
AU (1) AU614714B2 (de)
CA (1) CA1339830C (de)
DE (1) DE3789333T2 (de)
DK (1) DK169582B1 (de)
ES (1) ES2050114T3 (de)
IE (1) IE63109B1 (de)
IL (1) IL82926A (de)
PT (1) PT85149B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879212A (en) * 1986-04-02 1989-11-07 United Biomedical Inc. Peptide composition and method for the detection of antibodies to HTLV-III
US5166050A (en) * 1986-08-20 1992-11-24 Bristol-Myers Squibb Company Monoclonal antibodies and peptides useful in treating and diagnosing HIV infections
NZ221440A (en) * 1986-08-20 1991-11-26 Genetic Systems Corp Composition containing monoclonal antibodies/peptides useful in treating and diagnosing hiv infections
FI872409A0 (fi) * 1987-05-29 1987-05-29 Labsystems Oy Foerfarande foer detektering av hiv-1 motkroppar.
DE3855134T2 (de) * 1987-11-13 1996-10-02 Hermann Katinger Monoklonale menschliche antikörper gegen hiv-i
AU629528B2 (en) * 1988-01-27 1992-10-08 Biochem Pharma Inc. Synthetic peptides and mixtures thereof for detecting hiv antibodies
US5298419A (en) * 1988-03-31 1994-03-29 The Arizona Board Of Regents On Behalf Of The University Of Arizona Human hybridomas and monoclonal antibodies which bind both gp41 and gp120 envelope proteins of human immunodeficiency virus
CA1339775C (en) * 1988-06-10 1998-03-24 Shuzo Matsushita Antibody 0.5b to hiv-i gp 120 modified with toxic substance
JPH0292298A (ja) * 1988-09-30 1990-04-03 Olympus Optical Co Ltd Ｈｉｖ構成蛋白に対するモノクローナル抗体
US5731189A (en) * 1989-02-28 1998-03-24 New York University Human monoclonal antibodies to human immunodeficiency virus
WO1990009805A1 (en) * 1989-02-28 1990-09-07 New York University Human monoclonal antibodies to human immunodeficiency virus
WO1990010457A1 (en) * 1989-03-14 1990-09-20 New York University Method of treating hiv infections using immunotoxins
US6248574B1 (en) 1989-12-13 2001-06-19 Avigdor Shaffermann Polypeptides selectively reactive with antibodies against human immunodeficiency virus and vaccines comprising the polypeptides
FR2657017B1 (fr) * 1990-01-16 1995-08-18 Clonatec Sa Peptides derivant de la glycoproteine d'enveloppe du virus-hiv-1, leurs applications a la detection d'une infection due a ce virus et a la vaccination contre le sida.
EP0438332B1 (de) * 1990-01-16 1998-04-08 Orgenics Ltd. Peptide, von Virus-HIV-Hüllen-Glycoproteinen abstammend, deren Verwendung zum Nachweis einer Infektion dieser Viren und für die Impfung gegen AIDS
DE19809785C2 (de) * 1998-03-08 2000-02-10 Wolfgang Bergter Radioimmunpharmakon zur Behandlung der HIV-1-Infektion
US6680209B1 (en) 1999-12-06 2004-01-20 Biosite, Incorporated Human antibodies as diagnostic reagents
EP1751115A4 (de) 2004-05-23 2010-10-20 Gerard M Housey Theramuteinmodulatoren
US8431110B2 (en) 2005-05-23 2013-04-30 Hmi Medical Innovations, Llc. Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators
WO2017093985A1 (en) 2015-12-05 2017-06-08 Centre Hospitalier Universitaire Vaudois Hiv binding agents

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4520113A (en) 1984-04-23 1985-05-28 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Serological detection of antibodies to HTLV-III in sera of patients with AIDS and pre-AIDS conditions
US9328391B1 (en) * 1984-08-22 2016-05-03 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Cloning and expression of HIV-1 DNA
IE64785B1 (en) * 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
FR2580177B2 (fr) * 1985-04-15 1989-06-02 Pasteur Institut Antigenes apparentes a la glycoproteine d'enveloppe du virus du sida, notamment precurseurs de cette glycoproteine, procedes d'obtention de ces antigenes et moyens mis en oeuvre dans ces procedes, applications de ces antigenes a la preparation de compositions immunogenes ou pour le diagnostic du sida ou des affections qui lui sont apparentees
WO1986006414A1 (en) * 1985-04-29 1986-11-06 Genetic Systems Corporation Synthetic antigens for the detection of aids-related disease
JP2702911B2 (ja) * 1985-09-11 1998-01-26 ユナイテツド・バイオメデイカル・インコ−ポレ−テツド 合成ペプチド、並びにそれを用いたエイズおよびプリ・エイズの検出方法
US4772547A (en) * 1986-02-03 1988-09-20 Hoffmann-La Roche Inc. HTLV-III envelope peptides
US4904581A (en) * 1986-05-06 1990-02-27 Epitope, Inc. Method of detecting AIDS virus infection
AU8127187A (en) * 1986-12-03 1988-06-09 Ici Australia Operations Proprietary Limited Mine roof supporting element

Also Published As

Publication number Publication date
AU7451287A (en) 1987-12-24
JPS63107998A (ja) 1988-05-12
EP0251612A2 (de) 1988-01-07
DE3789333T2 (de) 1994-07-07
PT85149A (en) 1987-07-01
JP2626680B2 (ja) 1997-07-02
PT85149B (pt) 1990-07-31
IE871587L (en) 1987-12-23
KR880000585A (ko) 1988-03-28
IE63109B1 (en) 1995-03-22
CA1339830C (en) 1998-04-21
ES2050114T3 (es) 1994-05-16
DK304087A (da) 1987-12-24
IL82926A0 (en) 1987-12-20
DE3789333D1 (de) 1994-04-21
DK169582B1 (da) 1994-12-12
KR910001808B1 (ko) 1991-03-26
AU614714B2 (en) 1991-09-12
IL82926A (en) 1991-07-18
EP0251612A3 (en) 1990-05-23
EP0251612B1 (de) 1994-03-16
DK304087D0 (da) 1987-06-15

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee