ATE104699T1 - Hervorrufung physischer veraenderungen in pflanzen durch verwendung von negativstrangigen rnas. - Google Patents
Hervorrufung physischer veraenderungen in pflanzen durch verwendung von negativstrangigen rnas.Info
- Publication number
- ATE104699T1 ATE104699T1 AT8686307850T AT86307850T ATE104699T1 AT E104699 T1 ATE104699 T1 AT E104699T1 AT 8686307850 T AT8686307850 T AT 8686307850T AT 86307850 T AT86307850 T AT 86307850T AT E104699 T1 ATE104699 T1 AT E104699T1
- Authority
- AT
- Austria
- Prior art keywords
- negative
- plants
- stranged
- rnas
- physical changes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y105/00—Oxidoreductases acting on the CH-NH group of donors (1.5)
- C12Y105/01—Oxidoreductases acting on the CH-NH group of donors (1.5) with NAD+ or NADP+ as acceptor (1.5.1)
- C12Y105/01019—D-Nopaline dehydrogenase (1.5.1.19), i.e. D-nopaline synthase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/788,002 US6617496B1 (en) | 1985-10-16 | 1985-10-16 | Effecting virus resistance in plants through the use of negative strand RNAs |
| EP86307850A EP0223399B1 (de) | 1985-10-16 | 1986-10-10 | Hervorrufung physischer Veränderungen in Pflanzen durch Verwendung von negativstrangigen RNAs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE104699T1 true ATE104699T1 (de) | 1994-05-15 |
Family
ID=25143142
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT8686307850T ATE104699T1 (de) | 1985-10-16 | 1986-10-10 | Hervorrufung physischer veraenderungen in pflanzen durch verwendung von negativstrangigen rnas. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6617496B1 (de) |
| EP (1) | EP0223399B1 (de) |
| AT (1) | ATE104699T1 (de) |
| AU (1) | AU607122B2 (de) |
| BR (1) | BR8605043A (de) |
| CA (1) | CA1341556C (de) |
| DE (1) | DE3689802T2 (de) |
Families Citing this family (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4751181A (en) * | 1984-12-31 | 1988-06-14 | Duke University | Methods and compositions useful in the diagnosis and treatment of autoimmune diseases |
| ATE201444T1 (de) * | 1985-03-21 | 2001-06-15 | Johnston Stephen Ph D | Vom parasit abgeleiteter widerstand |
| US6608241B1 (en) | 1985-10-29 | 2003-08-19 | Monsanto Technology Llc | Protection of plants against viral infection |
| US5453566A (en) * | 1986-03-28 | 1995-09-26 | Calgene, Inc. | Antisense regulation of gene expression in plant/cells |
| NZ219472A (en) * | 1986-03-28 | 1990-08-28 | Calgene Inc | Regulation of phenotype in plant cells using dsdna constructs |
| US5107065A (en) * | 1986-03-28 | 1992-04-21 | Calgene, Inc. | Anti-sense regulation of gene expression in plant cells |
| AU612972B2 (en) * | 1986-04-02 | 1991-07-25 | Pioneer Hi-Bred International, Inc. | Virus resistant plants having antisense rna |
| JPH02500325A (ja) * | 1986-08-26 | 1990-02-08 | マッコーリー・ユニバーシティー | 斑入り |
| US6737560B1 (en) | 1988-02-03 | 2004-05-18 | Pioneer Hi-Bred International, Inc. | Molecular methods of hybrid seed production |
| US6191343B1 (en) | 1988-02-03 | 2001-02-20 | Pioneer Hi-Bred International | Molecular methods of hybrid seed production |
| US5356799A (en) * | 1988-02-03 | 1994-10-18 | Pioneer Hi-Bred International, Inc. | Antisense gene systems of pollination control for hybrid seed production |
| US5728926A (en) * | 1988-02-03 | 1998-03-17 | Pioneer Hi-Bred International, Inc. | Antisense gene systems of pollination control for hybrid seed production |
| NL8800756A (nl) * | 1988-03-25 | 1989-10-16 | Vereniging Voor Christelijk Wetenschappelijk Onderwijs | Genetisch gemanipuleerde plantecellen en planten, alsmede daarvoor bruikbaar recombinant dna. |
| DE3810286A1 (de) * | 1988-03-25 | 1989-10-12 | Max Planck Gesellschaft | Transgene pflanze mit modifizierter physiologie, morphologie und modifiziertem hormonmetabolismus, gewebekulturen dieser pflanze und verfahren zu ihrer herstellung |
| US5260205A (en) * | 1990-11-14 | 1993-11-09 | Philip Morris Incorporated | Method of purifying putrescine N-methyltransferase from tobacco plant extract with a polyamine |
| US6013859A (en) * | 1994-07-14 | 2000-01-11 | Pioneer Hi-Bred International, Inc. | Molecular methods of hybrid seed production |
| US6586661B1 (en) | 1997-06-12 | 2003-07-01 | North Carolina State University | Regulation of quinolate phosphoribosyl transferase expression by transformation with a tobacco quinolate phosphoribosyl transferase nucleic acid |
| AUPP249298A0 (en) | 1998-03-20 | 1998-04-23 | Ag-Gene Australia Limited | Synthetic genes and genetic constructs comprising same I |
| CN101818145A (zh) | 1998-03-20 | 2010-09-01 | 联邦科学和工业研究组织 | 控制基因表达 |
| US8598332B1 (en) | 1998-04-08 | 2013-12-03 | Bayer Cropscience N.V. | Methods and means for obtaining modified phenotypes |
| US20040214330A1 (en) | 1999-04-07 | 2004-10-28 | Waterhouse Peter Michael | Methods and means for obtaining modified phenotypes |
| CN1202246C (zh) | 1998-04-08 | 2005-05-18 | 联邦科学和工业研究组织 | 获得修饰表型的方法和措施 |
| US6759574B1 (en) | 1998-11-05 | 2004-07-06 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Plants having enhanced gall resistance and methods and compositions for producing same |
| EP2336337B1 (de) | 1998-11-12 | 2015-07-29 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Chimäre Promotoren, befähigt zur Vermittlung der Genexpression in Pflanzen bei Infektion mit Pathogenen sowie deren Verwendungen |
| ES2250173T3 (es) | 1999-07-20 | 2006-04-16 | Gvs Gesellschaft Fur Erwerb Und Verwertung Von Schutzrechten Mbh | Nuevo metodo para la generacion y seleccion de plantas de linaza o lino transgenicas. |
| US6423885B1 (en) | 1999-08-13 | 2002-07-23 | Commonwealth Scientific And Industrial Research Organization (Csiro) | Methods for obtaining modified phenotypes in plant cells |
| EP1724355A3 (de) | 2000-08-30 | 2007-05-23 | North Carolina State University | Transgene Pflanzen, die molekulare Decoys enthalten, die den Proteininhalt ändern |
| JP2004533807A (ja) | 2000-11-07 | 2004-11-11 | ノース・キャロライナ・ステイト・ユニヴァーシティ | プトレッシン−ｎ−メチルトランスフェラーゼプロモーター |
| JP5283814B2 (ja) | 2000-11-09 | 2013-09-04 | コモンウェルス サイエンティフィック アンドインダストリアル リサーチ オーガナイゼーション | Ｓｓｉｉ活性が低下したオオムギならびにアミロペクチン含有量が低下したデンプンおよびデンプン含有生成物 |
| CA2449920A1 (en) | 2001-06-08 | 2002-12-19 | Vector Tobacco Ltd. | Modifying nicotine and nitrosamine levels in tobacco |
| CA2478904A1 (en) | 2002-03-14 | 2003-09-18 | Commonwealth Scientific And Industrial Research Organisation | Modified gene-silencing rna and uses thereof |
| EP2311964A1 (de) | 2003-04-11 | 2011-04-20 | CropDesign N.V. | Verfahren zur Steigerung der Stresstoleranz in Pflanzen |
| WO2005001098A1 (en) | 2003-06-30 | 2005-01-06 | Commonwealth Scientific And Industrial Research Organisation | Wheat with altered branching enzyme activity and starch and starch containing products derived thereform |
| EP2868749B1 (de) | 2004-01-20 | 2017-10-04 | Monsanto Technology LLC | Chimäre Promotoren zur Verwendung in Pflanzen |
| US7453025B2 (en) | 2004-09-22 | 2008-11-18 | Arborgen, Llc | Reproductive ablation constructs |
| JP5638736B2 (ja) | 2004-12-30 | 2014-12-10 | コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガナイゼーション | 腸の健康を改善する方法および手段 |
| WO2007035752A2 (en) | 2005-09-20 | 2007-03-29 | J.R. Simplot Company | Low acrylamide foods |
| US7838729B2 (en) | 2007-02-26 | 2010-11-23 | Monsanto Technology Llc | Chloroplast transit peptides for efficient targeting of DMO and uses thereof |
| US20090123626A1 (en) * | 2007-09-28 | 2009-05-14 | J.R. Simplot Company | Reduced acrylamide plants and foods |
| WO2009082208A2 (en) | 2007-12-21 | 2009-07-02 | Keygene N.V. | Trichome specific promoters |
| EP2100962A1 (de) | 2008-03-12 | 2009-09-16 | Biogemma | Pflanzen mit verbesserter Widerstandsfähigkeit gegen Pathogene |
| CN103333894B (zh) | 2008-04-07 | 2016-11-23 | 孟山都技术公司 | 植物调控元件及其应用 |
| US20120277117A1 (en) | 2009-02-27 | 2012-11-01 | Adel Zayed | Hydroponic apparatus and methods of use |
| MX336182B (es) | 2009-06-08 | 2016-01-11 | Nunhems Bv | Plantas tolerantes a la sequia. |
| WO2011050271A1 (en) | 2009-10-23 | 2011-04-28 | Monsanto Technology Llc | Methods and compositions for expression of transgenes in plants |
| CA3121068C (en) | 2010-01-14 | 2023-11-28 | Monsanto Technology Llc | Plant regulatory elements and uses thereof |
| EP2575430A1 (de) | 2010-05-28 | 2013-04-10 | Nunhems B.V. | Pflanzen mit grösserer fruchtgrösse |
| ES2657233T3 (es) | 2010-08-30 | 2018-03-02 | Dow Agrosciences, Llc | Potenciador viral baciliforme de la caña de azúcar (SCBV) y su uso en la genómica vegetal funcional |
| US8648230B2 (en) | 2011-03-18 | 2014-02-11 | Ms Technologies, Llc | Regulatory regions preferentially expressing in non-pollen plant tissue |
| RU2644205C2 (ru) | 2011-03-25 | 2018-02-08 | Монсанто Текнолоджи Ллс | Регуляторные элементы растений и их применение |
| CA2835817C (en) | 2011-05-13 | 2020-07-07 | Monsanto Technology Llc | Plant regulatory elements and uses thereof |
| AU2013202941B2 (en) | 2012-02-29 | 2015-06-25 | Dow Agrosciences Llc | Sugarcane bacilliform viral (SCBV) enhancer and its use in plant functional genomics |
| WO2013134651A1 (en) | 2012-03-09 | 2013-09-12 | Board Of Trustees Of Michigan State University | Method of enhancing plant drought tolerance by expression of ndr1 |
| US9663793B2 (en) | 2012-04-20 | 2017-05-30 | Monsanto Technology, Llc | Plant regulatory elements and uses thereof |
| CA2895184C (en) | 2012-12-19 | 2021-11-23 | Monsanto Technology Llc | Plant regulatory elements and uses thereof |
| KR102495527B1 (ko) | 2013-03-14 | 2023-02-06 | 몬산토 테크놀로지 엘엘씨 | 식물 조절 성분 및 이의 용도 |
| RU2675524C2 (ru) | 2013-03-14 | 2018-12-19 | Монсанто Текнолоджи Ллс | Регуляторные элементы растений и их применение |
| EP3274462A4 (de) | 2015-03-26 | 2018-12-26 | The Texas A&M University System | Umwandlung von lignin in biokunststoffe und lipidbrennstoffe |
| IL257831B2 (en) | 2015-09-04 | 2025-11-01 | Keygene Nv | Diplosporic garden |
| MX385929B (es) | 2016-03-11 | 2025-03-18 | Monsanto Technology Llc | Elementos reguladores vegetales y sus usos. |
| JP7078551B2 (ja) | 2016-05-24 | 2022-05-31 | モンサント テクノロジー エルエルシー | 植物調節エレメント及びその使用 |
| WO2018005589A1 (en) | 2016-06-28 | 2018-01-04 | Cellectis | Altering expression of gene products in plants through targeted insertion of nucleic acid sequences |
| CR20240086A (es) | 2017-01-19 | 2024-09-30 | Monsanto Technology Llc | ELEMENTOS REGULATORIOS DE PLANTAS Y SUS USOS (Divisional 2019-0377) |
| EP3737747A1 (de) | 2018-01-12 | 2020-11-18 | The Texas A&M University System | Erhöhung des ertrags von pflanzenbioprodukten |
| US11499159B2 (en) | 2019-01-10 | 2022-11-15 | Monsanto Technology Llc | Plant regulatory elements and uses thereof |
| WO2022204460A1 (en) | 2021-03-26 | 2022-09-29 | Flagship Pioneering Innovations Vii, Llc | Compositions and methods for producing circular polyribonucleotides |
| EP4314289A1 (de) | 2021-03-26 | 2024-02-07 | Flagship Pioneering Innovations VII, LLC | Herstellung von zirkulären polyribonukleotiden in einem prokaryotischen system |
| EP4314281A1 (de) | 2021-03-26 | 2024-02-07 | Flagship Pioneering Innovations VII, LLC | Herstellung von zirkulären polyribonukleotiden in einem eukaryotischen system |
| WO2023077118A1 (en) | 2021-11-01 | 2023-05-04 | Flagship Pioneering Innovations Vii, Llc | Polynucleotides for modifying organisms |
| KR20240135651A (ko) | 2022-01-20 | 2024-09-11 | 플래그쉽 파이어니어링 이노베이션스 Vii, 엘엘씨 | 유기체를 변형하기 위한 폴리뉴클레오티드 |
| US20240093220A1 (en) | 2022-09-09 | 2024-03-21 | Friedrich Alexander Universität Erlangen-Nürnberg | Plant regulatory elements and uses thereof |
| EP4705474A2 (de) | 2023-05-03 | 2026-03-11 | Flagship Pioneering Innovations VII, LLC | Künstliche tymovirale satelliten rnas |
| EP4705476A1 (de) | 2023-05-03 | 2026-03-11 | Flagship Pioneering Innovations VII, LLC | Künstliche amalgavirus-satelliten-rnas |
| AR132591A1 (es) | 2023-05-03 | 2025-07-16 | Flagship Pioneering Innovations Vii Llc | Arn satélite de secoviridae artificiales |
| AR132589A1 (es) | 2023-05-03 | 2025-07-16 | Flagship Pioneering Innovations Vii Llc | Arn satélite de solemoviridae artificiales |
| CN121712898A (zh) | 2023-05-03 | 2026-03-20 | 旗舰创业创新第七有限责任公司 | 用于植物的内源核糖核酸病毒卫星rna扩增系统 |
| EP4705470A1 (de) | 2023-05-03 | 2026-03-11 | Flagship Pioneering Innovations VII, LLC | Künstliche tombusviridae-satelliten-rnas |
| CN121712897A (zh) | 2023-05-03 | 2026-03-20 | 旗舰创业创新第七有限责任公司 | 用于植物的分体病毒卫星rna扩增系统 |
| AR132592A1 (es) | 2023-05-03 | 2025-07-16 | Flagship Pioneering Innovations Vii Llc | Arn satélite de ghabrivirales artificiales |
| EP4705478A1 (de) | 2023-05-03 | 2026-03-11 | Flagship Pioneering Innovations VII, LLC | Künstliche morellivirale satelliten-rnas |
| US20250075226A1 (en) | 2023-08-29 | 2025-03-06 | University Of Freiburg | Proteins for regulation of symbiotic infection and associated regulatory elements |
| WO2026006779A1 (en) | 2024-06-27 | 2026-01-02 | The Regents Of The University Of California | Transgenic plants expressing fern rapid non-photochemical quenching (npq) proteins |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0126546B2 (de) * | 1983-04-15 | 1994-03-30 | Lubrizol Genetics Inc. | Expression von pflanzlichen strukturellen Genen |
| DE3486053T3 (de) | 1983-10-20 | 2004-01-08 | The Research Foundation Of State University Of New York | Regulierung von Gen-Expression durch Translationshemmung unter Verwendung von m-RNS hinderndem Komplementär-RNS. |
| US5580716A (en) * | 1985-03-21 | 1996-12-03 | Stephen A. Johnston | Parasite-derived resistance |
| NZ219472A (en) * | 1986-03-28 | 1990-08-28 | Calgene Inc | Regulation of phenotype in plant cells using dsdna constructs |
| EP0590301A2 (de) * | 1986-07-25 | 1994-04-06 | Louisiana State University and Agricultural and Mechanical College | Verfahren zum Schutz von Pflanzen gegen Krankheit und Befall, durch Geneinbau und diese Gene enthaltende Vektoren und Pflanzenzellen |
| AU7918387A (en) * | 1986-08-26 | 1988-03-24 | Macquarie University | Transformation of an organism using antisense rna or promoter occlusion technique |
-
1985
- 1985-10-16 US US06/788,002 patent/US6617496B1/en not_active Expired - Lifetime
-
1986
- 1986-10-02 CA CA000519667A patent/CA1341556C/en not_active Expired - Lifetime
- 1986-10-10 DE DE3689802T patent/DE3689802T2/de not_active Revoked
- 1986-10-10 AT AT8686307850T patent/ATE104699T1/de active
- 1986-10-10 EP EP86307850A patent/EP0223399B1/de not_active Revoked
- 1986-10-15 BR BR8605043A patent/BR8605043A/pt not_active Application Discontinuation
- 1986-10-15 AU AU63924/86A patent/AU607122B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0223399B1 (de) | 1994-04-20 |
| EP0223399A1 (de) | 1987-05-27 |
| CA1341556C (en) | 2007-10-09 |
| DE3689802D1 (de) | 1994-05-26 |
| DE3689802T2 (de) | 1994-11-17 |
| AU607122B2 (en) | 1991-02-28 |
| AU6392486A (en) | 1987-04-30 |
| US6617496B1 (en) | 2003-09-09 |
| BR8605043A (pt) | 1987-07-14 |
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