ATE104977T1 - Zwischenprodukt fuer 1-carba(dethia)cephalosporin. - Google Patents
Zwischenprodukt fuer 1-carba(dethia)cephalosporin.Info
- Publication number
- ATE104977T1 ATE104977T1 AT8989306173T AT89306173T ATE104977T1 AT E104977 T1 ATE104977 T1 AT E104977T1 AT 8989306173 T AT8989306173 T AT 8989306173T AT 89306173 T AT89306173 T AT 89306173T AT E104977 T1 ATE104977 T1 AT E104977T1
- Authority
- AT
- Austria
- Prior art keywords
- dethia
- carba
- cephalosporin
- cephem
- nitrobenzyl
- Prior art date
Links
- 229930186147 Cephalosporin Natural products 0.000 title 1
- 229940124587 cephalosporin Drugs 0.000 title 1
- 150000001780 cephalosporins Chemical class 0.000 title 1
- 125000006503 p-nitrobenzyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])* 0.000 abstract 2
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 238000005947 deacylation reaction Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/02—Preparation
- C07D463/06—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20959688A | 1988-06-22 | 1988-06-22 | |
| EP89306173A EP0348124B1 (de) | 1988-06-22 | 1989-06-19 | Zwischenprodukt für 1-Carba(dethia)cephalosporin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE104977T1 true ATE104977T1 (de) | 1994-05-15 |
Family
ID=22779423
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT8989306173T ATE104977T1 (de) | 1988-06-22 | 1989-06-19 | Zwischenprodukt fuer 1-carba(dethia)cephalosporin. |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0348124B1 (de) |
| JP (1) | JP2809711B2 (de) |
| KR (1) | KR0138264B1 (de) |
| AT (1) | ATE104977T1 (de) |
| CA (1) | CA1334971C (de) |
| DE (1) | DE68914888T2 (de) |
| ES (1) | ES2063129T3 (de) |
| HU (1) | HU207864B (de) |
| IE (1) | IE63268B1 (de) |
| IL (1) | IL90660A0 (de) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4208515A (en) * | 1973-02-23 | 1980-06-17 | Eli Lilly And Company | 3-Halo cephalosporins |
| IE49377B1 (en) * | 1979-02-01 | 1985-10-02 | Lilly Co Eli | Process for preparation of beta-lactam compounds |
| EP0175544A3 (de) * | 1984-09-17 | 1987-06-03 | Eli Lilly And Company | Verfahren zur Herstellung von Cephalosporinzwischenverbindungen |
| US4665171A (en) * | 1985-07-17 | 1987-05-12 | Harvard University | Process and intermediates for β-lactam antibiotics |
| US4714760A (en) * | 1985-08-20 | 1987-12-22 | Bristol-Myers Company | Cephalosporin intermediates |
| US4782144A (en) * | 1987-09-14 | 1988-11-01 | Eli Lilly And Company | 1-carba(dethia)-3-hydroxy-3-cephem ester crystalline and crystalline solvate thereof |
-
1989
- 1989-06-19 AT AT8989306173T patent/ATE104977T1/de not_active IP Right Cessation
- 1989-06-19 ES ES89306173T patent/ES2063129T3/es not_active Expired - Lifetime
- 1989-06-19 DE DE68914888T patent/DE68914888T2/de not_active Expired - Fee Related
- 1989-06-19 IL IL90660A patent/IL90660A0/xx not_active IP Right Cessation
- 1989-06-19 CA CA000603239A patent/CA1334971C/en not_active Expired - Fee Related
- 1989-06-19 JP JP1158119A patent/JP2809711B2/ja not_active Expired - Fee Related
- 1989-06-19 EP EP89306173A patent/EP0348124B1/de not_active Expired - Lifetime
- 1989-06-20 KR KR1019890008487A patent/KR0138264B1/ko not_active Expired - Lifetime
- 1989-06-21 IE IE201789A patent/IE63268B1/en not_active IP Right Cessation
- 1989-06-21 HU HU893178A patent/HU207864B/hu not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2809711B2 (ja) | 1998-10-15 |
| JPH0245484A (ja) | 1990-02-15 |
| EP0348124B1 (de) | 1994-04-27 |
| EP0348124A2 (de) | 1989-12-27 |
| DE68914888T2 (de) | 1994-09-15 |
| IL90660A0 (en) | 1990-01-18 |
| IE63268B1 (en) | 1995-04-05 |
| ES2063129T3 (es) | 1995-01-01 |
| KR900000363A (ko) | 1990-01-30 |
| KR0138264B1 (ko) | 1998-05-15 |
| HUT50341A (en) | 1990-01-29 |
| CA1334971C (en) | 1995-03-28 |
| HU207864B (en) | 1993-06-28 |
| EP0348124A3 (en) | 1990-05-09 |
| DE68914888D1 (de) | 1994-06-01 |
| IE892017L (en) | 1989-12-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |