ATE105476T1 - Dihydropyridin-verbindung zur verbesserung der adernausdehnung und hemmung der herzhypertrophie. - Google Patents
Dihydropyridin-verbindung zur verbesserung der adernausdehnung und hemmung der herzhypertrophie.Info
- Publication number
- ATE105476T1 ATE105476T1 AT8888121280T AT88121280T ATE105476T1 AT E105476 T1 ATE105476 T1 AT E105476T1 AT 8888121280 T AT8888121280 T AT 8888121280T AT 88121280 T AT88121280 T AT 88121280T AT E105476 T1 ATE105476 T1 AT E105476T1
- Authority
- AT
- Austria
- Prior art keywords
- compound
- cardiac hypertrophy
- venetic
- dilonation
- dihydropyridin
- Prior art date
Links
- 206010007572 Cardiac hypertrophy Diseases 0.000 title abstract 3
- 208000006029 Cardiomegaly Diseases 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- -1 dihydropyridine compound Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000006501 nitrophenyl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP33558187 | 1987-12-29 | ||
| EP88121280A EP0323604B1 (de) | 1987-12-29 | 1988-12-20 | Dihydropyridin-Verbindung zur Verbesserung der Adernausdehnung und Hemmung der Herzhypertrophie |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE105476T1 true ATE105476T1 (de) | 1994-05-15 |
Family
ID=18290181
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT8888121280T ATE105476T1 (de) | 1987-12-29 | 1988-12-20 | Dihydropyridin-verbindung zur verbesserung der adernausdehnung und hemmung der herzhypertrophie. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5032601A (de) |
| EP (1) | EP0323604B1 (de) |
| KR (1) | KR970009076B1 (de) |
| AT (1) | ATE105476T1 (de) |
| CA (1) | CA1318596C (de) |
| DE (1) | DE3889532T2 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5258393A (en) * | 1990-02-21 | 1993-11-02 | Fujisawa Pharmaceutical Co., Ltd. | Use of a dihydropyridine compound for improving inner ear microcirculation |
| EP0447812B1 (de) * | 1990-02-21 | 1996-01-10 | Fujisawa Pharmaceutical Co., Ltd. | Verwendung eines Dihydropyridins zur Verbesserung der Blutzirkulation des inneren Ohres |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4284634A (en) * | 1975-07-02 | 1981-08-18 | Fujisawa Pharmaceutical Co., Ltd. | 1,4-Dihydropyridine derivatives, and pharmaceutical method of the same |
| US4338322A (en) * | 1975-07-02 | 1982-07-06 | Fujisawa Pharmaceutical Co., Ltd. | 1,4-Dihydropyridine derivatives, pharmaceutical compositions containing same and methods of effecting vasodilation using same |
| CA1117117A (en) * | 1978-10-10 | 1982-01-26 | Fujisawa Pharmaceutical Co., Ltd. | 2-methyl-dihydropyridine compound, processes for preparation thereof and pharmaceutical composition comprising the same |
| US4782070A (en) * | 1986-07-01 | 1988-11-01 | Fujisawa Pharmaceutical Co., Ltd. | Cerebral dysfunction therapeutic agent, which comprises a dihydropyridine compound |
-
1988
- 1988-12-20 AT AT8888121280T patent/ATE105476T1/de active
- 1988-12-20 EP EP88121280A patent/EP0323604B1/de not_active Expired - Lifetime
- 1988-12-20 DE DE3889532T patent/DE3889532T2/de not_active Expired - Fee Related
- 1988-12-20 CA CA000586478A patent/CA1318596C/en not_active Expired - Fee Related
- 1988-12-27 KR KR1019880017544A patent/KR970009076B1/ko not_active Expired - Fee Related
- 1988-12-27 US US07/289,665 patent/US5032601A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0323604B1 (de) | 1994-05-11 |
| KR900009076A (ko) | 1990-07-02 |
| DE3889532T2 (de) | 1994-08-25 |
| EP0323604A3 (de) | 1991-07-31 |
| KR970009076B1 (ko) | 1997-06-05 |
| CA1318596C (en) | 1993-06-01 |
| DE3889532D1 (de) | 1994-06-16 |
| US5032601A (en) | 1991-07-16 |
| EP0323604A2 (de) | 1989-07-12 |
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