ATE106251T1 - Immunkomplexe. - Google Patents

Immunkomplexe.

Info

Publication number
ATE106251T1
ATE106251T1 AT91903666T AT91903666T ATE106251T1 AT E106251 T1 ATE106251 T1 AT E106251T1 AT 91903666 T AT91903666 T AT 91903666T AT 91903666 T AT91903666 T AT 91903666T AT E106251 T1 ATE106251 T1 AT E106251T1
Authority
AT
Austria
Prior art keywords
substance
immune complexes
monoclonal antibody
biologically active
immune complex
Prior art date
Application number
AT91903666T
Other languages
English (en)
Inventor
Naoru Hamaguchi
Jun Sato
Kazuhiro Doken
Susumu Iwasa
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2287648A external-priority patent/JPH03279335A/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE106251T1 publication Critical patent/ATE106251T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6813—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin the drug being a peptidic cytokine, e.g. an interleukin or interferon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6815—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT91903666T 1990-02-06 1991-02-05 Immunkomplexe. ATE106251T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2740790 1990-02-06
JP8018290 1990-03-28
JP2287648A JPH03279335A (ja) 1990-02-06 1990-10-24 免疫複合体

Publications (1)

Publication Number Publication Date
ATE106251T1 true ATE106251T1 (de) 1994-06-15

Family

ID=27285782

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91903666T ATE106251T1 (de) 1990-02-06 1991-02-05 Immunkomplexe.

Country Status (6)

Country Link
EP (1) EP0514544B1 (de)
JP (1) JP3260364B2 (de)
AT (1) ATE106251T1 (de)
CA (1) CA2073964A1 (de)
DE (1) DE69102265T2 (de)
WO (1) WO1991012022A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ263102A (en) * 1993-03-19 1997-05-26 Immunex Corp Pharmaceutical compositions comprising a ligand protein such as interleukin-4 and a soluble receptor protein that binds thereto
CA2282501A1 (en) * 1997-02-19 1998-08-27 Centocor, Inc. Sustained drug delivery and compositions useful therefor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2148299B (en) * 1983-09-01 1988-01-06 Hybritech Inc Antibody compositions of therapeutic agents having an extended serum half-life
IE63847B1 (en) * 1989-05-05 1995-06-14 Res Dev Foundation A novel antibody delivery system for biological response modifiers

Also Published As

Publication number Publication date
EP0514544A1 (de) 1992-11-25
WO1991012022A1 (en) 1991-08-22
EP0514544B1 (de) 1994-06-01
CA2073964A1 (en) 1991-08-07
JPH06509541A (ja) 1994-10-27
DE69102265D1 (de) 1994-07-07
JP3260364B2 (ja) 2002-02-25
DE69102265T2 (de) 1994-10-13

Similar Documents

Publication Publication Date Title
LV10178A (lv) Fiziologiski saderigu glabajot stabilu cilveka olbaltumvielu preparatu iegusanas panemiens
ATE113650T1 (de) Ausgewählte stämme von lactobacillus enthaltende pharmazeutische zusammensetzungen.
DE69126664D1 (de) Bestimmung von analyten in biologischen flüssigkeiten in gegenwart von störenden substanzen
DE3685625D1 (de) Antikoerperkomplexe von haptenmodifizierten diagnostischen oder therapeutischen mitteln.
NO844017L (no) Spormerkede konjugater av metallothionein og maalsoekende biologiske aktive molekyler
KR930702519A (ko) 동물 및 사람에서의 감염을 치료 및 예방하는 신규한 항체
FI925098A7 (fi) Ihmisen papilloomavirusten 1,5,6,8,11,16,18,31,33 ja 56 synteettisiä p eptidejä, jotka ovat käyttökelpoisia immunoanalyysissä diagnostisiin t arkoituksiin
SE8605295D0 (sv) Monoclonal antibodies cross-reactive and crossprotective against p. aeruginosa serotypes
NZ221440A (en) Composition containing monoclonal antibodies/peptides useful in treating and diagnosing hiv infections
SE8300320L (sv) Anvendning av en saltlosning av monoklonala antikroppar med relativt hog salthalt vid blodgruppsbestemning
ID25978A (id) Antibodi anti-fas
IT7948832A0 (it) Composizione e procedimento per la determinazione della concentrazione del glucosio in fluidi corporei
ZA773259B (en) Improvements in or relating to methods for reducing the doses of biologically active substances while maintaining the biological effects
ATE7107T1 (de) Mittel zur behandlung von colitis ulcerosa, enteritis regionalis crohn (morbus crohn), chronischer unspezifischer colitis und divertikulitis sowie verwendung von salicylazobenzoesaeure, zur herstellung von derartigen mitteln.
DE69102265D1 (de) Immunkomplexe.
NO981454D0 (no) Anti-FAS-antistoffer
AU584690B2 (en) E87ag antigen of pseudomonas aeruginosa, monoclonal antibody against it, and hybridoma
IT8125358A0 (it) Bioprotesi valvolare cardiaca e suo procedimento di ottenimento.
DE58907767D1 (de) Pflegeset insbesondere für den Reisebedarf.
FI905726A7 (fi) Erityisesti magneettisten vektoripotentiaalien käyttö materiaalien käsittelyyn
IL84040A (en) Monoclonal antibodies against ifn-omega,their preparation and their use in the purification and detection of ifn-omega
DK225689A (da) Anvendelse af metalloporphyriner til modvirkning af den toksiske virkning af tumorterapi
EP0338395A3 (en) Monoclonal antibodies to pseudomonas aeruginosa, their production and use
UA26438A (uk) СПОСІБ ОТРИМАHHЯ СУЛЬФОHІЛФЕHІЛ- БЕttА-D-ТІОКСИЛОЗИДІВ
ATE36333T1 (de) Hydantoin enthaltende therapeutische mittel.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties