ATE107313T1 - Synthetisches pseudomonas aeruginosa pilin-peptid und verwandte impfstoffe und diagnostika. - Google Patents

Synthetisches pseudomonas aeruginosa pilin-peptid und verwandte impfstoffe und diagnostika.

Info

Publication number
ATE107313T1
ATE107313T1 AT90906800T AT90906800T ATE107313T1 AT E107313 T1 ATE107313 T1 AT E107313T1 AT 90906800 T AT90906800 T AT 90906800T AT 90906800 T AT90906800 T AT 90906800T AT E107313 T1 ATE107313 T1 AT E107313T1
Authority
AT
Austria
Prior art keywords
amino acid
aeruginosa
diagnostics
pseudomonas aeruginosa
immunogens
Prior art date
Application number
AT90906800T
Other languages
English (en)
Inventor
Robert S Hodges
William Paranchych
Kok K Lee
Sastry A Parami
Randall T Irvin
Peter C Doig
Original Assignee
Univ Alberta
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Alberta filed Critical Univ Alberta
Application granted granted Critical
Publication of ATE107313T1 publication Critical patent/ATE107313T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT90906800T 1989-04-28 1990-04-26 Synthetisches pseudomonas aeruginosa pilin-peptid und verwandte impfstoffe und diagnostika. ATE107313T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34456589A 1989-04-28 1989-04-28

Publications (1)

Publication Number Publication Date
ATE107313T1 true ATE107313T1 (de) 1994-07-15

Family

ID=23351056

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90906800T ATE107313T1 (de) 1989-04-28 1990-04-26 Synthetisches pseudomonas aeruginosa pilin-peptid und verwandte impfstoffe und diagnostika.

Country Status (9)

Country Link
US (2) US5445818A (de)
EP (1) EP0469045B1 (de)
JP (1) JP2963536B2 (de)
AT (1) ATE107313T1 (de)
AU (1) AU5533490A (de)
CA (3) CA1340530C (de)
DE (1) DE69010001T2 (de)
DK (1) DK0469045T3 (de)
WO (1) WO1990013563A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5494672A (en) * 1989-04-28 1996-02-27 S.P.I. Synthetic Peptides Incorporated Pseudomonas peptide composition and method
US5223604A (en) * 1991-06-25 1993-06-29 S.P.I. Synthetic Peptides Incorporated Pseudomonas exoenzyme s peptide composition and method
CN1148578C (zh) 1994-07-25 2004-05-05 罗切诊断学有限公司 免疫测定特异抗体的方法、所用试剂、抗原及其用途
US6872398B2 (en) * 1995-12-22 2005-03-29 The United States Of America As Represented By The Secretary Of The Army Conjugate vaccine against gram-negative bacterial infections
US6270777B1 (en) * 1996-12-20 2001-08-07 University Technologies International Inc. Conserved metalloprotease epitopes
US20030054012A1 (en) * 2000-05-12 2003-03-20 Fitzgerald David J. Pseudomonas exotoxin a-like chimeric immunogens for eliciting a secretory iga-mediated immune response
ES2249838T3 (es) * 1997-07-11 2006-04-01 The Government Of The Usa As Represented By The Secretary Of The Depar. Of Health And Human Services Inmunogenos quimericos similares a la exotoxina a de pseudomonas.
US7314632B1 (en) * 1997-07-11 2008-01-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Pseudomonas exotoxin A-like chimeric immunogens
US6342233B1 (en) * 1998-06-12 2002-01-29 Governors Of The University Of Alberta Pseudomonas treatment composition and method
US20030228324A1 (en) * 1999-05-06 2003-12-11 Malcolm Andrew J. Peptide compositions and methods of producing and using same
US6863896B1 (en) * 1999-10-26 2005-03-08 Chiron Corporation Plant lectins as mucosal adjuvants
ATE425180T1 (de) * 2000-12-21 2009-03-15 Us Gov Health & Human Serv Ein chimäres protein das nichttoxische pseudomonas exotoxin a und typ iv pilin sequenzen enthält
US7132101B2 (en) 2002-02-27 2006-11-07 Duquesne University Of The Holy Ghost Compositions and methods for eliciting an immune response to gram-negative bacterial infections
WO2006041906A2 (en) 2004-10-04 2006-04-20 Trinity Biosystems, Inc. Methods and compositions for immunizing against pseudomonas infection
WO2007089272A2 (en) 2005-07-22 2007-08-09 The Regents Of The University Of Colorado, A Body Corporate Non-toxic biofilm inhibitor
EP2528622A2 (de) 2010-01-26 2012-12-05 The Regents of the University of Colorado In doppelsträngige doppelwendel templierte influenzavirusepitope und ihre verwendung in der immunisierung
BR112016021383A2 (pt) 2014-03-24 2017-10-03 Genentech Inc Método para identificar um paciente com câncer que é susceptível ou menos susceptível a responder ao tratamento com um antagonista de cmet, método para identificar um paciente apresentando câncer previamente tratado, método para determinar a expressão do biomarcador hgf, antagonista anti-c-met e seu uso, kit de diagnóstico e seu método de preparo
KR20200018483A (ko) 2017-06-14 2020-02-19 비로메틱스 아게 호흡기 합포체 바이러스에 대한 방어를 위한 고리형 펩티드
JP7550762B2 (ja) 2018-12-20 2024-09-13 ヴァイロメティックス アーゲー リポペプチドビルディングブロックおよび合成ウイルス様粒子
EP4216992A1 (de) 2020-09-28 2023-08-02 DBV Technologies Partikel mit einem rsv-f-protein zur verwendung bei der rsv-impfung
CN121693342A (zh) 2023-07-12 2026-03-17 维罗迈科斯股份公司 肺炎球菌抗原的组合物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0048422A3 (de) * 1980-09-15 1983-08-24 Bactex Incorporated Haare von Pseudomonas-Aeruginosa und deren Verwendung als Impfstoffe gegen infektiöse P.Aeruginosa
US4443549A (en) * 1981-10-19 1984-04-17 Molecular Genetics, Inc. Production of monoclonal antibodies against bacterial adhesins
US4886663A (en) * 1983-01-03 1989-12-12 Scripps Clinic And Research Foundation Synthetic heat-stable enterotoxin polypeptide of Escherichia coli and multimers thereof
AU577045B2 (en) * 1983-07-23 1988-09-15 Zahnradfabrik Friedrichshafen Ag Pressure medium control device
DK219084D0 (da) * 1984-05-02 1984-05-02 Frederik Carl Peter Lindberg Antigen
CA1256370A (en) * 1984-02-24 1989-06-27 Yuzuru Homma Toxoids of elastase of pseudomonas aeruginosa origin
US4702911A (en) * 1985-09-27 1987-10-27 Immunomed Corporation Preparation of bacterium pili subunits and vaccines containing pili subunits
CA1319101C (en) * 1986-09-03 1993-06-15 Marta Iris Sabara Rotavirus nucleocapsid protein with or without binding peptides as immunologic carriers for macromolecules
WO1988004665A1 (en) * 1986-12-22 1988-06-30 Trion Forskning- Och Utvecklings Aktiebolag A new pertussis toxin derived polypeptide and applications thereof
US5494672A (en) * 1989-04-28 1996-02-27 S.P.I. Synthetic Peptides Incorporated Pseudomonas peptide composition and method

Also Published As

Publication number Publication date
CA2053924C (en) 2003-10-21
CA1340530C (en) 1999-05-04
CA2053924A1 (en) 1990-10-29
WO1990013563A1 (en) 1990-11-15
DE69010001D1 (de) 1994-07-21
DE69010001T2 (de) 1994-09-22
DK0469045T3 (da) 1994-09-26
CA2443232A1 (en) 1990-10-29
EP0469045B1 (de) 1994-06-15
US5612036A (en) 1997-03-18
US5445818A (en) 1995-08-29
JPH04504719A (ja) 1992-08-20
JP2963536B2 (ja) 1999-10-18
AU5533490A (en) 1990-11-29
EP0469045A1 (de) 1992-02-05

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee