ATE108450T1 - Mevalonolactone vom typ pyrazolopyridin. - Google Patents

Mevalonolactone vom typ pyrazolopyridin.

Info

Publication number
ATE108450T1
ATE108450T1 AT89106401T AT89106401T ATE108450T1 AT E108450 T1 ATE108450 T1 AT E108450T1 AT 89106401 T AT89106401 T AT 89106401T AT 89106401 T AT89106401 T AT 89106401T AT E108450 T1 ATE108450 T1 AT E108450T1
Authority
AT
Austria
Prior art keywords
mevalonolactones
pyrazolopyridine
type
pyrazolopyridine type
chem
Prior art date
Application number
AT89106401T
Other languages
English (en)
Inventor
Yoshihiro Nissan Chem Fujikawa
Tsuboi-Cho
Mikio Nissan Chemical I Suzuki
Hiroshi Nissan Chemica Iwasaki
Mitsuaki Nissan Chem Sakashita
Kenkyusho Oaza- Seibutsukagaku
Masaki Nissan Chem Se Kitahara
Shiraoka-Machi Oaza-Shiraoka
Original Assignee
Nissan Chemical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Ind Ltd filed Critical Nissan Chemical Ind Ltd
Application granted granted Critical
Publication of ATE108450T1 publication Critical patent/ATE108450T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Enzymes And Modification Thereof (AREA)
AT89106401T 1988-04-26 1989-04-11 Mevalonolactone vom typ pyrazolopyridin. ATE108450T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP10309088 1988-04-26
JP27143988 1988-10-27
JP1684689 1989-01-26

Publications (1)

Publication Number Publication Date
ATE108450T1 true ATE108450T1 (de) 1994-07-15

Family

ID=27281590

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89106401T ATE108450T1 (de) 1988-04-26 1989-04-11 Mevalonolactone vom typ pyrazolopyridin.

Country Status (10)

Country Link
EP (1) EP0339358B1 (de)
JP (1) JP2890448B2 (de)
KR (1) KR970009222B1 (de)
AT (1) ATE108450T1 (de)
DE (1) DE68916685T2 (de)
DK (1) DK659089D0 (de)
FI (1) FI90870C (de)
HU (1) HU203888B (de)
NO (1) NO173501C (de)
WO (1) WO1989010365A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3130342B2 (ja) * 1991-10-04 2001-01-31 日産化学工業株式会社 動脈硬化性血管内膜肥厚抑制薬
AU2001242795A1 (en) 2000-03-27 2001-10-08 Takeda Chemical Industries Ltd. Condensed pyrazole derivatives, process for producing the same and use thereof
EP2170884A2 (de) * 2007-06-25 2010-04-07 Boehringer Ingelheim International GmbH Chemische verbindungen
US8173635B2 (en) 2007-11-02 2012-05-08 Vertex Pharmaceuticals Incorporated Kinase inhibitors
MD20140130A2 (ro) 2012-06-29 2015-04-30 Pfizer Inc. 4-(amino-substituite)-7H-pirolo[2,3-d]pirimidine noi ca inhibitori de LRRK2
WO2015092592A1 (en) 2013-12-17 2015-06-25 Pfizer Inc. Novel 3,4-disubstituted-1h-pyrrolo[2,3-b]pyridines and 4,5-disubstituted-7h-pyrrolo[2,3-c]pyridazines as lrrk2 inhibitors
CN108137586B (zh) 2015-09-14 2021-04-13 辉瑞大药厂 作为LRRK2抑制剂的新颖咪唑并[4,5-c]喹啉和咪唑并[4,5-c][1,5]萘啶衍生物
CN112313232B (zh) 2018-05-02 2024-03-08 Jw中外制药公司 新型杂环衍生物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984002131A1 (fr) * 1982-11-22 1984-06-07 Sandoz Ag Produits analogues de mevalolactone et leurs derives, leurs procedes de production, compositions pharmaceutiques les contenant ainsi que leur utilisation en tant que produits pharmaceutiques
FI860755A0 (fi) * 1984-06-22 1986-02-20 Sandoz Ag Pyrazolanaloger av mevolonolakton och deras derivat, foerfaranden foer deras framstaellning samt deras andvaendning.
US4761419A (en) * 1987-12-07 1988-08-02 Warner-Lambert Company 6-(((substituted)quinolinyl)ethyl)-and ethenyl)tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis
US4822799A (en) * 1988-01-27 1989-04-18 Sandoz Pharm. Corp. Pyrazolopyridine analogs of mevalonolactone and derivatives thereof useful for inhibiting cholesterol biosynthesis in mammals

Also Published As

Publication number Publication date
NO173501B (no) 1993-09-13
DK659089A (da) 1989-12-22
FI90870B (fi) 1993-12-31
KR900700480A (ko) 1990-08-13
KR970009222B1 (ko) 1997-06-09
JPH02275878A (ja) 1990-11-09
DE68916685D1 (de) 1994-08-18
NO173501C (no) 1993-12-22
DE68916685T2 (de) 1995-02-09
HU203888B (en) 1991-10-28
DK659089D0 (da) 1989-12-22
NO895165D0 (no) 1989-12-21
WO1989010365A1 (en) 1989-11-02
FI90870C (fi) 1994-04-11
EP0339358A1 (de) 1989-11-02
JP2890448B2 (ja) 1999-05-17
FI896251A0 (fi) 1989-12-22
EP0339358B1 (de) 1994-07-13
NO895165L (no) 1989-12-21
HU892751D0 (en) 1990-03-28

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties