ATE108490T1 - Hybridisierungssonden. - Google Patents

Hybridisierungssonden.

Info

Publication number
ATE108490T1
ATE108490T1 AT87304433T AT87304433T ATE108490T1 AT E108490 T1 ATE108490 T1 AT E108490T1 AT 87304433 T AT87304433 T AT 87304433T AT 87304433 T AT87304433 T AT 87304433T AT E108490 T1 ATE108490 T1 AT E108490T1
Authority
AT
Austria
Prior art keywords
hybrid
probe
base sequence
nucleotide
sequence
Prior art date
Application number
AT87304433T
Other languages
English (en)
Inventor
Francis Joseph Carr
Original Assignee
Bio Rad Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10598059&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE108490(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bio Rad Laboratories filed Critical Bio Rad Laboratories
Application granted granted Critical
Publication of ATE108490T1 publication Critical patent/ATE108490T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6858Allele-specific amplification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Surgical Instruments (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
AT87304433T 1986-05-19 1987-05-19 Hybridisierungssonden. ATE108490T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868612087A GB8612087D0 (en) 1986-05-19 1986-05-19 Hybridisation probes

Publications (1)

Publication Number Publication Date
ATE108490T1 true ATE108490T1 (de) 1994-07-15

Family

ID=10598059

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87304433T ATE108490T1 (de) 1986-05-19 1987-05-19 Hybridisierungssonden.

Country Status (7)

Country Link
EP (1) EP0246864B2 (de)
JP (2) JP2622255B2 (de)
AT (1) ATE108490T1 (de)
DE (1) DE3750198T3 (de)
ES (1) ES2058112T3 (de)
GB (1) GB8612087D0 (de)
HK (1) HK125195A (de)

Families Citing this family (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1323293C (en) * 1987-12-11 1993-10-19 Keith C. Backman Assay using template-dependent nucleic acid probe reorganization
US5449602A (en) * 1988-01-13 1995-09-12 Amoco Corporation Template-directed photoligation
US5093245A (en) * 1988-01-26 1992-03-03 Applied Biosystems Labeling by simultaneous ligation and restriction
IE61148B1 (en) * 1988-03-10 1994-10-05 Ici Plc Method of detecting nucleotide sequences
JP2856804B2 (ja) * 1988-03-24 1999-02-10 ユニバーシティ オブ アイオワ リサーチ ファウンデイション 標識された相補的核酸プローブを開裂する触媒反応の補因子としての活性に基づく核酸配列検出のための触媒ハイブリッド形成系
US4988617A (en) * 1988-03-25 1991-01-29 California Institute Of Technology Method of detecting a nucleotide change in nucleic acids
CA1341584C (en) * 1988-04-06 2008-11-18 Bruce Wallace Method of amplifying and detecting nucleic acid sequences
US8148065B1 (en) * 1988-04-06 2012-04-03 City Of Hope Ligation amplification of nucleic acid sequences
ATE144556T1 (de) * 1988-06-24 1996-11-15 Amgen Inc Verfahren und mittel zum nachweis von nukleinsäuresequenzen
ATE138106T1 (de) * 1988-07-20 1996-06-15 David Segev Verfahren zur amplifizierung und zum nachweis von nukleinsäuresequenzen
US6004826A (en) * 1988-07-20 1999-12-21 David Segev Repair-mediated process for amplifying and detecting nucleic acid sequences
US5382511A (en) * 1988-08-02 1995-01-17 Gene Tec Corporation Method for studying nucleic acids within immobilized specimens
US5185243A (en) * 1988-08-25 1993-02-09 Syntex (U.S.A.) Inc. Method for detection of specific nucleic acid sequences
GB2225112A (en) * 1988-11-22 1990-05-23 Ici Plc Hybridisation probes
CA2005927A1 (en) * 1988-12-21 1990-06-21 Chander Bahl Method of preparing nucleotide probes using a bridging complement
ATE142272T1 (de) * 1989-01-19 1996-09-15 Behringwerke Ag Nukleinsäure-amplifikation unter verwendung eines einzelprimers
ATE143696T1 (de) * 1989-02-28 1996-10-15 Canon Kk Partiell doppelsträngiges oligonukleotid und verfahren zu seiner bildung
CA2012983A1 (en) * 1989-03-27 1990-09-27 Sydney Brenner Process for nucleic acid detection by binary amplification
US5091302A (en) * 1989-04-27 1992-02-25 The Blood Center Of Southeastern Wisconsin, Inc. Polymorphism of human platelet membrane glycoprotein iiia and diagnostic and therapeutic applications thereof
CA2035010C (en) * 1990-01-26 1996-12-10 Keith C. Backman Method of amplifying target nucleic acids applicable to both polymerase and ligase chain reactions
US5573907A (en) * 1990-01-26 1996-11-12 Abbott Laboratories Detecting and amplifying target nucleic acids using exonucleolytic activity
US5427930A (en) * 1990-01-26 1995-06-27 Abbott Laboratories Amplification of target nucleic acids using gap filling ligase chain reaction
US5516663A (en) * 1990-01-26 1996-05-14 Abbott Laboratories Ligase chain reaction with endonuclease IV correction and contamination control
US6013431A (en) 1990-02-16 2000-01-11 Molecular Tool, Inc. Method for determining specific nucleotide variations by primer extension in the presence of mixture of labeled nucleotides and terminators
EP0453301A3 (en) * 1990-04-20 1993-07-21 Syntex (U.S.A.) Inc. Double receptor polynucleotide assay method
US5494810A (en) * 1990-05-03 1996-02-27 Cornell Research Foundation, Inc. Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease
US5210015A (en) * 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US5846710A (en) * 1990-11-02 1998-12-08 St. Louis University Method for the detection of genetic diseases and gene sequence variations by single nucleotide primer extension
US6004744A (en) 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer
US5981176A (en) * 1992-06-17 1999-11-09 City Of Hope Method of detecting and discriminating between nucleic acid sequences
US5695933A (en) * 1993-05-28 1997-12-09 Massachusetts Institute Of Technology Direct detection of expanded nucleotide repeats in the human genome
ES2240970T3 (es) * 1993-11-03 2005-10-16 Orchid Biosciences, Inc. Polimorfismos de nucleotido simple y su uso en analisis geneticos.
EP0734457A1 (de) * 1994-01-26 1996-10-02 HYBRIDON, Inc. Verfahren für den Nachweis von Oligonnukleotiden in biologischen Flüssigkeiten
WO1995021271A1 (en) * 1994-02-07 1995-08-10 Molecular Tool, Inc. Ligase/polymerase-mediated genetic bit analysistm of single nucleotide polymorphisms and its use in genetic analysis
US5552278A (en) * 1994-04-04 1996-09-03 Spectragen, Inc. DNA sequencing by stepwise ligation and cleavage
US5831065A (en) * 1994-04-04 1998-11-03 Lynx Therapeutics, Inc. Kits for DNA sequencing by stepwise ligation and cleavage
US5714330A (en) * 1994-04-04 1998-02-03 Lynx Therapeutics, Inc. DNA sequencing by stepwise ligation and cleavage
USRE43097E1 (en) 1994-10-13 2012-01-10 Illumina, Inc. Massively parallel signature sequencing by ligation of encoded adaptors
US6013445A (en) * 1996-06-06 2000-01-11 Lynx Therapeutics, Inc. Massively parallel signature sequencing by ligation of encoded adaptors
GB9507238D0 (en) * 1995-04-07 1995-05-31 Isis Innovation Detecting dna sequence variations
US5728526A (en) * 1995-06-07 1998-03-17 Oncor, Inc. Method for analyzing a nucleotide sequence
EP0832287B1 (de) * 1995-06-07 2007-10-10 Solexa, Inc Oligonukleotid-tags zur sortierung und identifizierung
DE19610255B4 (de) * 1996-03-15 2004-11-04 Universität Heidelberg Verfahren zur Herstellung von Nukleinsäuresequenzen und Verfahren zum Nachweis von Translokationen zwischen Chromosomen
WO1997035033A1 (en) 1996-03-19 1997-09-25 Molecular Tool, Inc. Method for determining the nucleotide sequence of a polynucleotide
CA2255599C (en) 1996-04-25 2006-09-05 Bioarray Solutions, Llc Light-controlled electrokinetic assembly of particles near surfaces
IL129222A0 (en) 1996-10-01 2000-02-17 Geron Corp Telomerase reverse transcriptase
JP2001522244A (ja) 1997-04-24 2001-11-13 ユニバーシティ オブ ワシントン パルボウイルスベクターによる標的化した遺伝子改変
US6960457B1 (en) 1997-09-04 2005-11-01 Stanford University Reversible immobilization of arginine-tagged moieties on a silicate surface
US6492111B1 (en) * 1998-11-25 2002-12-10 Isis Pharmaceuticals, Inc. In situ binary synthesis of biologically effective molecules
WO2000031302A1 (en) * 1998-11-25 2000-06-02 Isis Pharmaceuticals, Inc. In situ binary synthesis of biologically effective molecules
US7014994B1 (en) 1999-03-19 2006-03-21 Cornell Research Foundation,Inc. Coupled polymerase chain reaction-restriction-endonuclease digestion-ligase detection reaction process
JP2002541475A (ja) * 1999-04-12 2002-12-03 ナノゲン/ベクトン・ディッキンソン・パートナーシップ 鎖置換増幅およびバイオエレクトロニック・マイクロチップ技術を用いる核酸配列の増幅および分離
JP4598338B2 (ja) * 1999-10-04 2010-12-15 オリンパス株式会社 核酸検出方法
EP1136568A4 (de) 1999-10-04 2004-12-15 Olympus Optical Corp Ltd Methode zum ermitteln der nukleinsäure
JP3668075B2 (ja) 1999-10-12 2005-07-06 光夫 板倉 遺伝物質シーケンス決定用懸濁系、その懸濁系を用いた遺伝物質シーケンス決定方法およびその懸濁系を用いたSNPs高速スコアリング方法
US7611869B2 (en) 2000-02-07 2009-11-03 Illumina, Inc. Multiplexed methylation detection methods
US7582420B2 (en) 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
US8076063B2 (en) 2000-02-07 2011-12-13 Illumina, Inc. Multiplexed methylation detection methods
US7955794B2 (en) 2000-09-21 2011-06-07 Illumina, Inc. Multiplex nucleic acid reactions
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
WO2004059289A2 (en) 2001-05-22 2004-07-15 Epicentre Technologies Target-dependent transcription using deletion mutants of n4 rna polymerase
US7291490B2 (en) 2001-06-11 2007-11-06 Ecopia Biosciences Inc. Nucleic acid fragment encoding an NRPS for the biosynthesis of anthramycin
WO2002101051A2 (en) 2001-06-11 2002-12-19 Ecopia Biosciences Inc. Genes and proteins for the biosynthesis of anthramycin
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
CA2497740C (en) 2001-10-15 2011-06-21 Bioarray Solutions, Ltd. Multiplexed analysis of polymorphic loci by probe elongation-mediated detection
EP1860200A1 (de) * 2001-12-03 2007-11-28 Illumina, Inc. Multiplexverfahren zur Methylierungsdetektion
CA2498320A1 (en) 2002-09-20 2004-04-01 Integrated Dna Technologies, Inc. Anthraquinone quencher dyes, their methods of preparation and use
AU2003283575A1 (en) * 2002-11-14 2004-06-03 John Nicholas Housby Polymorphism assay
AU2003298655A1 (en) 2002-11-15 2004-06-15 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
CA2539824C (en) 2003-09-22 2015-02-03 Xinwen Wang Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
CA2544041C (en) 2003-10-28 2015-12-08 Bioarray Solutions Ltd. Optimization of gene expression analysis using immobilized capture probes
WO2005049849A2 (en) 2003-11-14 2005-06-02 Integrated Dna Technologies, Inc. Fluorescence quenching azo dyes, their methods of preparation and use
AU2005222782B2 (en) 2004-02-04 2010-06-17 Ratiopharm Gmbh Methods of refolding mammalian glycosyltransferases
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
JP2008545659A (ja) 2005-05-20 2008-12-18 インテグレイテッド ディーエヌエイ テクノロジーズ インコーポレイテッド オリゴヌクレオチドを標識する化合物及び方法
EP2172563A1 (de) * 2008-09-24 2010-04-07 bioMérieux S.A. Verfahren zur Verringerung der Abhängigkeit von Sequenzvariationen eines Nukleinsäuretargets in einem diagnostischen Hybridisierungs-Assay
US9506057B2 (en) 2010-03-26 2016-11-29 Integrated Dna Technologies, Inc. Modifications for antisense compounds
EP2553123B1 (de) 2010-03-26 2016-08-24 Integrated DNA Technologies, Inc. Verfahren zur verstärkung einer nukleinsäurehybridisierung
AU2011299233B2 (en) 2010-09-07 2016-09-15 Integrated Dna Technologies, Inc. Modifications for antisense compounds
EP2633049B1 (de) 2010-10-27 2018-10-10 Harrisvaccines Inc Verfahren und zusammensetzungen zum schutz von wirbellosen wassertieren gegen krankheiten
CN103635584B (zh) 2011-04-12 2017-10-27 冈戈根股份有限公司 嵌合抗菌多肽
DK2729580T3 (en) 2011-07-08 2015-12-14 Keygene Nv SEQUENCE BASED genotyping BASED ON OLIGONUKLEOTIDLIGERINGSASSAYS
BR112015009103A2 (pt) 2012-10-23 2017-07-04 Harrisvaccines Inc método para proteger um animal invertebrado aquático contra o vírus da mionecrose infecciosa (imnv), método para produzir um composição e composição
CN105264076B (zh) 2013-01-28 2019-09-13 堪萨斯州立大学研究基金会 裂谷热病毒糖蛋白gn和gc及其用途
US20170136102A1 (en) 2014-03-27 2017-05-18 Umender Kumar SHARMA Phage-derived compositions for improved mycobacterial therapy
CN111770687A (zh) 2017-12-14 2020-10-13 拜克多科利尔私人控股有限公司 治疗性细菌素
AU2019287163B2 (en) 2018-06-12 2025-08-21 Keygene N.V. Nucleic acid amplification method
CA3127572A1 (en) 2019-02-21 2020-08-27 Keygene N.V. Genotyping of polyploids
IL309032A (en) 2021-06-03 2024-02-01 Mazen Animal Health Inc Oral administration of coronavirus spike protein to alter cytokine levels and provide passive immunity to newborn pigs

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1190838A (en) * 1981-07-17 1985-07-23 Cavit Akin Homogeneous nucleic acid hybridization diagnostics by non-radiative energy transfer
CA1222680A (en) * 1983-07-05 1987-06-09 Nanibhushan Dattagupta Testing dna samples for particular nucleotide sequences
US4883750A (en) * 1984-12-13 1989-11-28 Applied Biosystems, Inc. Detection of specific sequences in nucleic acids
EP0224126A3 (de) * 1985-11-25 1989-02-01 The University of Calgary Kovalent gekoppelte komplementäre Oligodeoxynukleotide zur Verwendung als "Primer Linkers" bei Sequenzierung von Nukleinsäuren
EP0245206A1 (de) * 1986-05-05 1987-11-11 IntraCel Corporation Analytisches Verfahren zum Nachweis und zur Messung einer spezifisch sequentierten Nukleinsäure

Also Published As

Publication number Publication date
EP0246864B1 (de) 1994-07-13
EP0246864A2 (de) 1987-11-25
JP2622255B2 (ja) 1997-06-18
DE3750198D1 (de) 1994-08-18
DE3750198T3 (de) 2008-01-03
EP0246864A3 (en) 1989-08-23
JPS6322197A (ja) 1988-01-29
JPH09182591A (ja) 1997-07-15
ES2058112T3 (es) 1994-11-01
EP0246864B2 (de) 2007-05-23
HK125195A (en) 1995-08-11
GB8612087D0 (en) 1986-06-25
DE3750198T2 (de) 1995-01-26
JP2683336B2 (ja) 1997-11-26

Similar Documents

Publication Publication Date Title
DE3750198D1 (de) Hybridisierungssonden.
FI891126A0 (fi) Foerfarande foer detektering av nukleotidsekvenser.
SE8604436L (sv) Hybridiseringsforfarande for detektion av polynukleotidsekvens
JPS6460390A (en) Breeding method for assay of polynucleotide
RO86356A (ro) Metoda de identificare microbiana
FI900602A0 (fi) Bestaemning.
DE3480487D1 (en) Nucleic acid hybridization assay
EP0317239A3 (de) Verfahren und Vorrichtung zum Nachweis von Restriktionsfragmentlängenpolymorphien
ES8707343A1 (es) Un metodo para aislar una secuencia de acido nucleico objetivo seleccionada
DE3650720D1 (de) Einschrittverfahren und Polynukleotidverbindungen zur Hybridisierung mit Ziel-Polynukleotiden
DK0666927T3 (da) Fremgangsmåde til påvisning af en nukleinsyresekvens.
EP0707075A3 (de) Spezies-spezifischer Nachweis von Mycobacterium Kansasii
ATE78301T1 (de) Molekulare genetische sonde und verfahren zu ihrer herstellung, testmethode und satz in denen diese molekulare genetische sonde gebraucht wird.
DE69027910D1 (de) Nukleinsäuresonden zum Nachweis von Chlamydia trachomatis und Chlamydia psittaci
DE69022167D1 (de) Nukleinsäuresonden zum nachweis von staphylococcus aureus.
NO874164L (no) Masseundersoekelsesmetode for deteksjon av enkeltbasemutasjoner i multiple loci i genomisk dna ved bruk av denatureringsgradient-gelelektroforese fulgt av effektiv overfoeringog hybredisering til forskjellige prober.
ATE127856T1 (de) Nukleinsäuresonden für die detektion von neisseria gonorrhoeae.
AU589362B2 (en) Polynucleotide hybridization probes
DE68925457D1 (de) Diagnoseverfahren für infektionskrankheiten sowie verfahren zum nachweis und identifizierung von mikroorganismen

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties