ATE108556T1 - Magnetische trennvorrichtung und verfahren zur anwendung in heterogenen prüfungen. - Google Patents

Magnetische trennvorrichtung und verfahren zur anwendung in heterogenen prüfungen.

Info

Publication number
ATE108556T1
ATE108556T1 AT88310810T AT88310810T ATE108556T1 AT E108556 T1 ATE108556 T1 AT E108556T1 AT 88310810 T AT88310810 T AT 88310810T AT 88310810 T AT88310810 T AT 88310810T AT E108556 T1 ATE108556 T1 AT E108556T1
Authority
AT
Austria
Prior art keywords
receiving
heterogenous
tests
application
separation device
Prior art date
Application number
AT88310810T
Other languages
English (en)
Inventor
May K Li
Jack Kessler
David T Bach
Original Assignee
Gene Trak Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gene Trak Systems filed Critical Gene Trak Systems
Application granted granted Critical
Publication of ATE108556T1 publication Critical patent/ATE108556T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/28—Magnetic plugs and dipsticks
    • B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302—Apparatus specially adapted for immunological test procedures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N2035/1025—Fluid level sensing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1065—Multiple transfer devices

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Cell Separators (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT88310810T 1987-11-16 1988-11-16 Magnetische trennvorrichtung und verfahren zur anwendung in heterogenen prüfungen. ATE108556T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12119187A 1987-11-16 1987-11-16

Publications (1)

Publication Number Publication Date
ATE108556T1 true ATE108556T1 (de) 1994-07-15

Family

ID=22395146

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88310810T ATE108556T1 (de) 1987-11-16 1988-11-16 Magnetische trennvorrichtung und verfahren zur anwendung in heterogenen prüfungen.

Country Status (5)

Country Link
EP (1) EP0317286B1 (de)
JP (1) JP2701891B2 (de)
AT (1) ATE108556T1 (de)
AU (1) AU621316B2 (de)
DE (1) DE3850635T2 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5139933A (en) * 1989-09-26 1992-08-18 Vicam, L.P. Assay method for detecting listeria
CA2026245A1 (en) * 1990-06-28 1991-12-29 Calvert L. Green Assay method for detecting viable listeria
WO1992005443A1 (en) * 1990-09-15 1992-04-02 Medical Research Council Reagent separation
EP0479448A3 (en) * 1990-10-02 1992-12-23 Beckman Instruments, Inc. Magnetic separation device
FR2671876B1 (fr) * 1991-01-22 1993-04-02 Brunet Paul Appareil melangeur pour reactions sur plaque en immuno-hematologie.
US5242833A (en) * 1991-03-20 1993-09-07 Reference Diagnostics, Inc. Lipid fractionation
US6664114B1 (en) 1992-08-03 2003-12-16 Sapidyne Instruments, Inc. Solid phase assay for detection of ligands
FI932866A0 (fi) * 1993-06-21 1993-06-21 Labsystems Oy Separeringsfoerfarande
FI930440A0 (fi) 1993-02-01 1993-02-01 Labsystems Oy Bestaemningsfoerfarande
DE69429159T2 (de) * 1993-02-01 2002-08-14 Thermo Labsystems Oy, Helsinki Verfahren für einen spezifischen Bindungstest mit magnetischen Teilchen
WO1994020855A1 (en) * 1993-03-04 1994-09-15 Sapidyne, Inc. Assay flow apparatus and method
DE59410037D1 (de) * 1993-09-17 2002-03-14 Hoffmann La Roche Analysengerät mit einer Vorrichtung zum Abtrennen magnetischer Mikropartikel
US5567326A (en) * 1994-09-19 1996-10-22 Promega Corporation Multisample magnetic separation device
US5646263A (en) * 1994-09-19 1997-07-08 Promega Corporation High efficiency method for isolating target substances using a multisample separation device
US5693784A (en) * 1994-09-19 1997-12-02 Promega Corporation Methods for creating agglomerates from colloidal particles
FI944938A0 (fi) * 1994-10-20 1994-10-20 Labsystems Oy Foerflyttningsanordning
FI944940A0 (fi) * 1994-10-20 1994-10-20 Labsystems Oy Tvaofasigt separeringsfoerfarande
FI944939A0 (fi) * 1994-10-20 1994-10-20 Labsystems Oy Foerfarande foer separering av partiklar
FI944937A0 (fi) 1994-10-20 1994-10-20 Labsystems Oy Separeringsanordning
GB2300258A (en) * 1995-04-28 1996-10-30 Philip John Jewess A separation device for magnetisable particles
US5776784A (en) * 1996-01-11 1998-07-07 Dade International Inc. Apparatus and method for reagent separation in a chemical analyzer
FR2758884B1 (fr) 1997-01-30 1999-04-02 Bio Merieux Procede pour isoler, notamment detecter ou quantifier un analyte dans un milieu
ATE446141T1 (de) 1997-11-14 2009-11-15 Gen Probe Inc Arbeitsgerät zur analyse
US6805840B1 (en) * 1998-03-19 2004-10-19 Precision Systems Science Co., Ltd. Apparatus for integrated process of magnetic particles and method of controlling the same
US7220596B2 (en) 1998-04-15 2007-05-22 Utah State University Real time detection of antigens
DE19854003A1 (de) * 1998-11-18 2000-05-25 Jenoptik Jena Gmbh Simultanes Magnetpartikelhandling in zweidimensionaler Anordnung
WO2001011364A1 (en) * 1999-08-09 2001-02-15 Precision System Science Co., Ltd. Method for automatic labeling using dispenser, method for automatically separating target substance, method for determining base sequence, and automatic dispensing system
DE20119542U1 (de) * 2000-11-30 2002-04-18 Institut für Physikalische Hochtechnologie e.V., 07745 Jena Anordnung zur Herstellung, Testung und Archivierung von festphasengebundenen chemischen oder biologischen Bibliotheken
EP1621890A1 (de) 2004-07-26 2006-02-01 bioMerieux B.V. Gerät und Methode zur Separation, Mischung und Konzentrierung magnetischer Partikel mit Flüssigkeiten und deren Verwendungen in Reinigungsmethoden
EP2030689B1 (de) * 2007-08-31 2013-02-13 Tecan Trading AG Mikroplatten-Träger mit Magneten
EP2565260B1 (de) 2010-04-30 2020-12-23 Bioneer Corporation Vorrichtung zur automatischen reinigung biologischer proben mit einer magnetfeld-anwendungseinheit, verfahren zur extraktion eines targets aus einer biologischen probe sowie proteinexpressions- und -reinigungsverfahren
EP2732878B1 (de) * 2012-11-20 2018-09-12 QIAGEN GmbH Magnetisches Regalsystem und Verfahren zur Verwendung eines magnetischen Regalsystems
CA2939910A1 (en) * 2014-02-18 2015-08-27 Drugarray, Inc. Multi-well separation apparatus and reagent delivery device
WO2023129146A1 (en) * 2021-12-29 2023-07-06 Tecan Genomics, Inc. Dispensing unit
CN122374099A (zh) * 2023-12-15 2026-07-10 株式会社日立高新技术 磁性粒子分离装置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0030086B2 (de) * 1979-11-13 1990-03-14 TECHNICON INSTRUMENTS CORPORATION (a New York corporation) Vereinigung von Reaktionsbehältern, Teile für ihre Herstellung und manuelles Immunoassayverfahren
GB2111407B (en) * 1981-11-16 1985-11-27 George Henry Jones Rotary magnetic separators
CA1220168A (en) * 1983-09-09 1987-04-07 Henry J. Rahn Magnetic separator for solid phase immunoassays
GB8530360D0 (en) * 1985-12-10 1986-01-22 Gec Elliott Mech Handling Magnetic separators

Also Published As

Publication number Publication date
EP0317286A3 (en) 1990-08-01
DE3850635T2 (de) 1995-03-02
EP0317286A2 (de) 1989-05-24
DE3850635D1 (de) 1994-08-18
AU621316B2 (en) 1992-03-12
JPH01201156A (ja) 1989-08-14
JP2701891B2 (ja) 1998-01-21
AU2561988A (en) 1989-05-18
EP0317286B1 (de) 1994-07-13

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Legal Events

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EEIH Change in the person of patent owner
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties