ATE108997T1 - Orales präparat von buspiron und seinen salzen. - Google Patents

Orales präparat von buspiron und seinen salzen.

Info

Publication number: ATE108997T1
Authority: AT; Austria
Prior art keywords: salts; buspiron; oral preparation; buspirone; bioavailability
Prior art date: 1987-10-22

Application number

AT88850347T

Other languages

English (en)

Inventor

Alf Gunnar Martin Nicklasson

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-10-22

Filing date

1988-10-17

Publication date

1994-08-15

1988-10-17 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

1994-08-15 Application granted granted Critical

1994-08-15 Publication of ATE108997T1 publication Critical patent/ATE108997T1/de

Links

QWCRAEMEVRGPNT-UHFFFAOYSA-N buspirone Chemical compound C1C(=O)N(CCCCN2CCN(CC2)C=2N=CC=CN=2)C(=O)CC21CCCC2 QWCRAEMEVRGPNT-UHFFFAOYSA-N 0.000 abstract 1
229960002495 buspirone Drugs 0.000 abstract 1
238000013270 controlled release Methods 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
238000013265 extended release Methods 0.000 abstract 1
238000009472 formulation Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Cosmetics (AREA)
Plural Heterocyclic Compounds (AREA)

AT88850347T 1987-10-22 1988-10-17 Orales präparat von buspiron und seinen salzen. ATE108997T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE8704097A SE8704097D0 (sv)	1987-10-22	1987-10-22	Oral formulation of buspirone and salts thereof

Publications (1)

Publication Number	Publication Date
ATE108997T1 true ATE108997T1 (de)	1994-08-15

Family

ID=20369959

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88850347T ATE108997T1 (de)	1987-10-22	1988-10-17	Orales präparat von buspiron und seinen salzen.

Country Status (21)

Country	Link
EP (1)	EP0313535B1 (de)
JP (1)	JP2674170B2 (de)
KR (1)	KR970004906B1 (de)
AT (1)	ATE108997T1 (de)
AU (1)	AU604585B2 (de)
CY (1)	CY1814A (de)
DE (1)	DE3850844T2 (de)
DK (1)	DK294489A (de)
ES (1)	ES2056955T3 (de)
FI (1)	FI100303B (de)
HK (1)	HK21295A (de)
HU (1)	HU204998B (de)
IE (1)	IE64705B1 (de)
IL (1)	IL88020A (de)
NO (1)	NO892512D0 (de)
NZ (1)	NZ226604A (de)
PT (1)	PT88820B (de)
SE (1)	SE8704097D0 (de)
WO (1)	WO1989003676A1 (de)
YU (1)	YU47903B (de)
ZA (1)	ZA887624B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU208495B (en) *	1990-06-27	1993-11-29	Alkaloida Vegyeszeti Gyar	Process for producing retarde pharmaceutical compositions
US5631017A (en) *	1993-03-26	1997-05-20	Beth Israel Deaconess Medical Center, Inc.	Topical application of buspirone for treatment of pathological conditions associated with immune responses
US5484788A (en) *	1993-03-26	1996-01-16	Beth Israel Hospital Association	Buspirone as a systemic immunosuppressant
DE4341156C2 (de) *	1993-12-02	1997-11-13	Wacker Chemie Gmbh	Verwendung von in Wasser redispergierbaren Kunststoffdispersionspulvern als Arzneimittelträger
US5478572A (en) *	1994-09-06	1995-12-26	Bristol-Myers Squibb Co.	Gepirone dosage form
US5637314A (en) *	1995-06-07	1997-06-10	Beth Israel Deaconess Medical Center, Inc.	Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis
GB9706089D0 (en) *	1997-03-24	1997-05-14	Scherer Ltd R P	Pharmaceutical composition
WO1999015172A1 (de) *	1997-09-25	1999-04-01	Bayer Aktiengesellschaft	Arzneimittelformulierung mit kontrollierter wirkstofffreisetzung
US6268368B1 (en) *	2000-03-01	2001-07-31	American Pharmaceuticals International	Anionic exchange polymer complexes of buspirone
US20250177310A1 (en) *	2022-02-16	2025-06-05	Cingulate Therapeutics LLC	Trimodal, precision-timed release tablet
CN117257747B (zh) *	2023-11-21	2024-01-30	泊诺(天津)创新医药研究有限公司	一种盐酸丁螺环酮片及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE759371A (fr) *	1969-11-24	1971-05-24	Bristol Myers Co	Azaspirodecanediones heterocycliques et procedes pour leur preparation
SE353229B (de) *	1970-06-04	1973-01-29	Haessle Ab
US4182703A (en) *	1978-01-09	1980-01-08	Eastman Kodak Company	Biheterocyclic ultraviolet stabilizers and their use in organic compositions
US4182763A (en) *	1978-05-22	1980-01-08	Mead Johnson & Company	Buspirone anti-anxiety method
US4693895A (en) *	1984-10-26	1987-09-15	Alza Corporation	Colon delivery system
US4634703A (en) *	1985-10-25	1987-01-06	Bristol-Myers Company	Method for alleviation of panic disorders
US4640921A (en) *	1986-02-04	1987-02-03	Bristol-Myers	Treatment of sexual dysfunction with buspirone

1987
- 1987-10-22 SE SE8704097A patent/SE8704097D0/xx unknown
1988
- 1988-10-12 IL IL88020A patent/IL88020A/xx unknown
- 1988-10-12 ZA ZA887624A patent/ZA887624B/xx unknown
- 1988-10-17 WO PCT/SE1988/000543 patent/WO1989003676A1/en not_active Ceased
- 1988-10-17 KR KR1019890701101A patent/KR970004906B1/ko not_active Expired - Fee Related
- 1988-10-17 JP JP63508883A patent/JP2674170B2/ja not_active Expired - Fee Related
- 1988-10-17 HU HU886266A patent/HU204998B/hu not_active IP Right Cessation
- 1988-10-17 AU AU26236/88A patent/AU604585B2/en not_active Ceased
- 1988-10-17 AT AT88850347T patent/ATE108997T1/de not_active IP Right Cessation
- 1988-10-17 DE DE3850844T patent/DE3850844T2/de not_active Expired - Fee Related
- 1988-10-17 EP EP88850347A patent/EP0313535B1/de not_active Expired - Lifetime
- 1988-10-17 ES ES88850347T patent/ES2056955T3/es not_active Expired - Lifetime
- 1988-10-18 NZ NZ226604A patent/NZ226604A/en unknown
- 1988-10-20 IE IE317788A patent/IE64705B1/en not_active IP Right Cessation
- 1988-10-20 YU YU196488A patent/YU47903B/sh unknown
- 1988-10-21 PT PT88820A patent/PT88820B/pt active IP Right Revival
1989
- 1989-06-15 DK DK294489A patent/DK294489A/da not_active Application Discontinuation
- 1989-06-16 NO NO892512A patent/NO892512D0/no unknown
- 1989-06-20 FI FI893017A patent/FI100303B/fi not_active IP Right Cessation
1995
- 1995-02-16 HK HK21295A patent/HK21295A/en not_active IP Right Cessation
- 1995-10-20 CY CY181495A patent/CY1814A/xx unknown

Also Published As

Publication number	Publication date
IL88020A (en)	1993-08-18
JP2674170B2 (ja)	1997-11-12
NO892512L (no)	1989-06-16
HU886266D0 (en)	1991-01-28
JPH02501744A (ja)	1990-06-14
DK294489D0 (da)	1989-06-15
YU47903B (sh)	1996-05-20
NZ226604A (en)	1991-07-26
AU2623688A (en)	1989-05-23
HK21295A (en)	1995-02-24
KR970004906B1 (ko)	1997-04-08
FI893017L (fi)	1989-06-20
IE883177L (en)	1989-04-22
DK294489A (da)	1989-06-15
EP0313535B1 (de)	1994-07-27
AU604585B2 (en)	1990-12-20
KR890701087A (ko)	1989-12-19
CY1814A (en)	1995-10-20
HUT54495A (en)	1991-03-28
PT88820B (pt)	1993-01-29
FI100303B (fi)	1997-11-14
IL88020A0 (en)	1989-06-30
DE3850844D1 (de)	1994-09-01
IE64705B1 (en)	1995-08-23
HU204998B (en)	1992-03-30
NO892512D0 (no)	1989-06-16
DE3850844T2 (de)	1994-12-08
ES2056955T3 (es)	1994-10-16
EP0313535A1 (de)	1989-04-26
WO1989003676A1 (en)	1989-05-05
FI893017A0 (fi)	1989-06-20
YU196488A (en)	1990-04-30
SE8704097D0 (sv)	1987-10-22
ZA887624B (en)	1989-06-28

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Legal Events

Date	Code	Title	Description
1995-02-15	UEP	Publication of translation of european patent specification
2005-07-15	REN	Ceased due to non-payment of the annual fee