ATE109161T1 - Hydrophobe bindungsstelle für adhäsionspeptide. - Google Patents

Hydrophobe bindungsstelle für adhäsionspeptide.

Info

Publication number: ATE109161T1
Authority: AT; Austria
Prior art keywords: peptides; biologically active; hydrophobic; binding site; domain
Prior art date: 1989-03-20

Application number

AT90905829T

Other languages

English (en)

Inventor

Michael D Pierschbacher

Cyril J Honsik

Lisa B Dreisbach

Original Assignee

Jolla Cancer Res Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-03-20

Filing date

1990-03-20

Publication date

1994-08-15

1990-03-20 Application filed by Jolla Cancer Res Found filed Critical Jolla Cancer Res Found

1994-08-15 Application granted granted Critical

1994-08-15 Publication of ATE109161T1 publication Critical patent/ATE109161T1/de

Links

230000002209 hydrophobic effect Effects 0.000 title abstract 5
102000004196 processed proteins & peptides Human genes 0.000 title abstract 5
108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
229940024606 amino acid Drugs 0.000 abstract 2
150000001413 amino acids Chemical class 0.000 abstract 2
235000014113 dietary fatty acids Nutrition 0.000 abstract 2
229930195729 fatty acid Natural products 0.000 abstract 2
239000000194 fatty acid Substances 0.000 abstract 2
150000004665 fatty acids Chemical class 0.000 abstract 2
IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 abstract 2
VKOBVWXKNCXXDE-UHFFFAOYSA-N icosanoic acid Chemical compound CCCCCCCCCCCCCCCCCCCC(O)=O VKOBVWXKNCXXDE-UHFFFAOYSA-N 0.000 abstract 2
AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 abstract 1
ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 abstract 1
COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 abstract 1
KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 abstract 1
ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 abstract 1
235000021314 Palmitic acid Nutrition 0.000 abstract 1
KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 abstract 1
-1 for example Chemical class 0.000 abstract 1
229960000310 isoleucine Drugs 0.000 abstract 1
AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 abstract 1
WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 abstract 1
COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 abstract 1
239000007787 solid Substances 0.000 abstract 1
125000006850 spacer group Chemical group 0.000 abstract 1
TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 abstract 1
239000004474 valine Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
- C07K17/02—Peptides being immobilised on, or in, an organic carrier
- C07K17/06—Peptides being immobilised on, or in, an organic carrier attached to the carrier via a bridging agent
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
General Engineering & Computer Science (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Cell Biology (AREA)
Microbiology (AREA)
Peptides Or Proteins (AREA)
Dental Preparations (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT90905829T 1989-03-20 1990-03-20 Hydrophobe bindungsstelle für adhäsionspeptide. ATE109161T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/326,168 US5120829A (en)	1989-03-20	1989-03-20	Hydrophobic attachment site for adhesion peptides

Publications (1)

Publication Number	Publication Date
ATE109161T1 true ATE109161T1 (de)	1994-08-15

Family

ID=23271081

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90905829T ATE109161T1 (de)	1989-03-20	1990-03-20	Hydrophobe bindungsstelle für adhäsionspeptide.

Country Status (9)

Country	Link
US (4)	US5120829A (de)
EP (1)	EP0464140B1 (de)
JP (1)	JP2723669B2 (de)
AT (1)	ATE109161T1 (de)
CA (1)	CA2046631A1 (de)
DE (1)	DE69011102T2 (de)
DK (1)	DK0464140T3 (de)
ES (1)	ES2057553T3 (de)
WO (1)	WO1990011297A1 (de)

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US6689165B2 (en)	2000-03-31	2004-02-10	Board Of Supervisors Of Louisana State University And Agricultural And Mechanical College	Surface modifications for enhanced epithelialization
JP4638653B2 (ja)	2000-08-16	2011-02-23	アコロジックスインコーポレイテッド	骨成長促進ペプチドを含む歯科用製品
US6911425B2 (en) *	2000-08-16	2005-06-28	Acologix, Inc.	Integrin binding motif containing peptides and methods of treating skeletal diseases
CA2441228A1 (en) *	2001-03-23	2002-10-03	Aphton Corporation	Combination treatment of pancreatic cancer
US20090191232A1 (en) *	2001-05-04	2009-07-30	Gevas Philip C	Combination therapy for the treatment of tumors
US20030021786A1 (en) *	2001-07-09	2003-01-30	Gevas Philip C.	Treatment and prevention of cancerous and pre-cancerous conditions of the liver, lung and esophagus
US6810583B2 (en) *	2001-08-07	2004-11-02	International Business Machines Corporation	Coupling of conductive vias to complex power-signal substructures
US6902932B2 (en) *	2001-11-16	2005-06-07	Tissue Regeneration, Inc.	Helically organized silk fibroin fiber bundles for matrices in tissue engineering
US20110009960A1 (en) *	2001-11-16	2011-01-13	Allergan, Inc.	Prosthetic fabric structure
GB0209896D0 (en)	2002-04-30	2002-06-05	Molmed Spa	Conjugate
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WO2004088326A2 (en) *	2003-03-28	2004-10-14	Aphton Corporation	Gastrin hormone immunoassays
US20060020119A1 (en) *	2004-03-29	2006-01-26	Stephen Grimes	Monoclonal antibodies to gastrin hormone
DK1794586T3 (da) *	2004-09-22	2013-05-13	Cancer Advances Inc	Monoklonale antistoffer til progastrin
WO2007011610A2 (en)	2005-07-18	2007-01-25	Acologix, Inc.	Protein formulation for promoting hard tissue formation
GB2433591A (en) *	2005-12-20	2007-06-27	Sharp Kk	Method for functionalising a hydrophobic substrate
GB2433505A (en) *	2005-12-20	2007-06-27	Sharp Kk	Capture agents for binding a ligand
GB2433506A (en) *	2005-12-20	2007-06-27	Sharp Kk	A method of producing a multimeric capture agent
CN101240028B (zh) *	2007-02-07	2010-08-18	首都医科大学	正十五烷基和rgd肽构建的缀合物、它们的合成及在医学中的应用
CN101240027B (zh) *	2007-02-07	2011-04-20	首都医科大学	正壬烷基和rgd肽构建的缀合物、它们的合成及在医学中的应用
CN101240031B (zh) *	2007-02-07	2010-10-13	首都医科大学	正十七烷基和rgd肽构建的缀合物、其制备方法及应用
CN101240029B (zh) *	2007-02-07	2010-08-11	首都医科大学	正庚烷基和rgd肽构建的缀合物、其合成方法和应用
CN101240030B (zh) *	2007-02-07	2010-08-11	首都医科大学	正十一烷基和rgd肽构建的缀合物、它们的合成及在医学中的应用
US8529897B2 (en)	2007-08-16	2013-09-10	Carnegie Mellon University	Inflammation-regulating compositions and methods
US20090246249A1 (en) *	2008-03-27	2009-10-01	Affinergy	Coating compositions having improved performance
US9308070B2 (en) *	2008-12-15	2016-04-12	Allergan, Inc.	Pliable silk medical device
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US9204953B2 (en)	2008-12-15	2015-12-08	Allergan, Inc.	Biocompatible surgical scaffold with varying stretch
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US9204954B2 (en) *	2008-12-15	2015-12-08	Allergan, Inc.	Knitted scaffold with diagonal yarn
US20110052695A1 (en) *	2009-04-20	2011-03-03	Allergan, Inc.	Drug delivery platforms comprising silk fibroin hydrogels and uses thereof
US20110111031A1 (en) *	2009-04-20	2011-05-12	Guang-Liang Jiang	Drug Delivery Platforms Comprising Silk Fibroin Hydrogels and Uses Thereof
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US20110184227A1 (en) *	2009-09-11	2011-07-28	Allergan, Inc.	Prosthetic device and method of manufacturing the same
US12150978B2 (en)	2017-06-15	2024-11-26	Cancer Advances Inc.	Compositions and methods for preventing tumors and cancer
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1989
- 1989-03-20 US US07/326,168 patent/US5120829A/en not_active Expired - Lifetime
1990
- 1990-03-20 CA CA002046631A patent/CA2046631A1/en not_active Abandoned
- 1990-03-20 DK DK90905829.9T patent/DK0464140T3/da active
- 1990-03-20 JP JP2505512A patent/JP2723669B2/ja not_active Expired - Lifetime
- 1990-03-20 ES ES90905829T patent/ES2057553T3/es not_active Expired - Lifetime
- 1990-03-20 AT AT90905829T patent/ATE109161T1/de not_active IP Right Cessation
- 1990-03-20 DE DE69011102T patent/DE69011102T2/de not_active Expired - Fee Related
- 1990-03-20 WO PCT/US1990/001486 patent/WO1990011297A1/en not_active Ceased
- 1990-03-20 EP EP90905829A patent/EP0464140B1/de not_active Expired - Lifetime
1992
- 1992-08-20 US US07/932,929 patent/US5587456A/en not_active Expired - Lifetime
1995
- 1995-05-05 US US08/435,317 patent/US5591822A/en not_active Expired - Lifetime
1996
- 1996-10-10 US US08/729,980 patent/US5760176A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JPH04506511A (ja)	1992-11-12
US5120829A (en)	1992-06-09
CA2046631A1 (en)	1990-09-21
EP0464140B1 (de)	1994-07-27
EP0464140A1 (de)	1992-01-08
JP2723669B2 (ja)	1998-03-09
DE69011102T2 (de)	1994-11-24
ES2057553T3 (es)	1994-10-16
DE69011102D1 (de)	1994-09-01
US5587456A (en)	1996-12-24
DK0464140T3 (da)	1994-09-05
US5591822A (en)	1997-01-07
WO1990011297A1 (en)	1990-10-04
US5760176A (en)	1998-06-02

Legal Events

Date	Code	Title	Description
1995-02-15	UEP	Publication of translation of european patent specification
1998-12-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE109161T1 (de)	1994-08-15	Hydrophobe bindungsstelle für adhäsionspeptide.
RO80806A (ro)	1983-02-01	Procedeu pentru obtinerea enzimatica a peptidelor
IL115199A (en)	2005-05-17	Composition comprising a polynucleic acid molecule in a liposome and method using said composition
DE69604147D1 (de)	1999-10-14	Flüssige zuzammensetzung zur stabilisierung von aminosäure-herbiziden
ES2124295T3 (es)	1999-02-01	Expresion y purificacion de factor tisular soluble recombinante.
DK0948358T4 (da)	2012-03-19	Stabile inteferon-væskeformuleringer
BG103439A (bg)	2000-01-31	Подобрения в или във връзка с диагностични/лечебни средства
BR9808668A (pt)	2000-07-11	Suspensão aquosa de microcápsulas compreendendo um material biologicamente ativo, e, processos para preparação de uma suspensão aquosa de microcápsulas aderentes e para aplicação de microcápsulas em um substrato pretendido
ES2038233T3 (es)	1993-07-16	Liquidos acondicionadores de substancia dental y osea.
MY106287A (en)	1995-04-29	Acid addition salts of amidated taurine or glycine, their preparation and use
NZ504486A (en)	2003-02-28	Attaching substances to micro-organisms
DE59906362D1 (de)	2003-08-28	Verwendung von lipopeptiden oder lipoproteinen zur wundbehandlung
ATE46703T1 (de)	1989-10-15	Regionspezifische determinanten fuer vitamin-k abhaengiges knochenprotein.
DE3160656D1 (en)	1983-08-25	Method of binding a biologically active material, e.g. a protein to a carrier containing hydroxyl groups
IE902389L (en)	1990-12-30	Enzymatically binding bioactive materials to proteins
CA2008817A1 (en)	1990-08-10	M-csf monoclonal antibodies that recognize a neutralizing conformational epitope
AU3850997A (en)	1998-03-06	Immunologically active proteins of borrelia burgdorferi, coded nuclein acids of such and their use in test kits and vaccines
ES8900018A1 (es)	1988-11-16	Procedimiento para la fabricacion de derivados aminoalcoholes peptidicos inhibidores de la renina y de las proteasas acidas
DE3581650D1 (de)	1991-03-14	Derivat von p-aminophenol mit mucrosekretolytischer fluessiger und antipyretischer wirksamkeit, dessen verfahren zur herstellung und dessen pharmazeutische zusammensetzungen.
DE69315730D1 (de)	1998-01-29	Verfahren zur Herstellung von Peptiden und neue Zwischenverbindungen dazu
WO1999001567A3 (en)	1999-04-01	Methods and compositions for a deubiquitinating enzyme and variants thereof
DE3585936D1 (de)	1992-06-04	Biologisch aktive peptide, deren verfahren zur herstellung und pharmazeutische zusammensetzungen.
TR199900933A2 (xx)	1999-11-22	Etkin, dikenli yapı proteni eşleniği.
TR199701463T1 (en)	1998-02-21	Sorbin asiti i�eren hidrojel.
GASPARIS	1984	COMPARISONS OF PURIFIED DOPAMINE-BETA-HYDROXYLASE FROM BOVINE LARGE DENSE CORED NORADRENERGIC VESICLES AND ADRENOMEDULLARY CHROMAFFIN GRANULES.