ATE109161T1 - Hydrophobe bindungsstelle für adhäsionspeptide. - Google Patents

Hydrophobe bindungsstelle für adhäsionspeptide.

Info

Publication number: ATE109161T1
Authority: AT; Austria
Prior art keywords: peptides; biologically active; hydrophobic; binding site; domain
Prior art date: 1989-03-20

Application number

AT90905829T

Other languages

English (en)

Inventor

Michael D Pierschbacher

Cyril J Honsik

Lisa B Dreisbach

Original Assignee

Jolla Cancer Res Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-03-20

Filing date

1990-03-20

Publication date

1994-08-15

1990-03-20 Application filed by Jolla Cancer Res Found filed Critical Jolla Cancer Res Found

1994-08-15 Application granted granted Critical

1994-08-15 Publication of ATE109161T1 publication Critical patent/ATE109161T1/de

Links

230000002209 hydrophobic effect Effects 0.000 title abstract 5
102000004196 processed proteins & peptides Human genes 0.000 title abstract 5
108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
229940024606 amino acid Drugs 0.000 abstract 2
150000001413 amino acids Chemical class 0.000 abstract 2
235000014113 dietary fatty acids Nutrition 0.000 abstract 2
229930195729 fatty acid Natural products 0.000 abstract 2
239000000194 fatty acid Substances 0.000 abstract 2
150000004665 fatty acids Chemical class 0.000 abstract 2
IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 abstract 2
VKOBVWXKNCXXDE-UHFFFAOYSA-N icosanoic acid Chemical compound CCCCCCCCCCCCCCCCCCCC(O)=O VKOBVWXKNCXXDE-UHFFFAOYSA-N 0.000 abstract 2
AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 abstract 1
ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 abstract 1
COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 abstract 1
KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 abstract 1
ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 abstract 1
235000021314 Palmitic acid Nutrition 0.000 abstract 1
KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 abstract 1
-1 for example Chemical class 0.000 abstract 1
229960000310 isoleucine Drugs 0.000 abstract 1
AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 abstract 1
WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 abstract 1
COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 abstract 1
239000007787 solid Substances 0.000 abstract 1
125000006850 spacer group Chemical group 0.000 abstract 1
TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 abstract 1
239000004474 valine Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
- C07K17/02—Peptides being immobilised on, or in, an organic carrier
- C07K17/06—Peptides being immobilised on, or in, an organic carrier attached to the carrier via a bridging agent
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
Wood Science & Technology (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
Gastroenterology & Hepatology (AREA)
Cell Biology (AREA)
Microbiology (AREA)
Toxicology (AREA)
General Engineering & Computer Science (AREA)
Peptides Or Proteins (AREA)
Dental Preparations (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT90905829T 1989-03-20 1990-03-20 Hydrophobe bindungsstelle für adhäsionspeptide. ATE109161T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/326,168 US5120829A (en)	1989-03-20	1989-03-20	Hydrophobic attachment site for adhesion peptides

Publications (1)

Publication Number	Publication Date
ATE109161T1 true ATE109161T1 (de)	1994-08-15

Family

ID=23271081

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90905829T ATE109161T1 (de)	1989-03-20	1990-03-20	Hydrophobe bindungsstelle für adhäsionspeptide.

Country Status (9)

Country	Link
US (4)	US5120829A (de)
EP (1)	EP0464140B1 (de)
JP (1)	JP2723669B2 (de)
AT (1)	ATE109161T1 (de)
CA (1)	CA2046631A1 (de)
DE (1)	DE69011102T2 (de)
DK (1)	DK0464140T3 (de)
ES (1)	ES2057553T3 (de)
WO (1)	WO1990011297A1 (de)

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US6689165B2 (en)	2000-03-31	2004-02-10	Board Of Supervisors Of Louisana State University And Agricultural And Mechanical College	Surface modifications for enhanced epithelialization
US7078021B2 (en)	2000-08-16	2006-07-18	Acologix, Inc.	Dental products comprising bone growth enhancing peptide
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JP2005508838A (ja) *	2001-03-23	2005-04-07	アフトンコーポレーション	膵癌の組合せ治療
US20090191232A1 (en) *	2001-05-04	2009-07-30	Gevas Philip C	Combination therapy for the treatment of tumors
AU2002326356A1 (en) *	2001-07-09	2003-01-29	Aphton Corporation	Treatment and prevention of cancerous and pre-cancerous conditions of the liver, lung and esophagus
US6810583B2 (en) *	2001-08-07	2004-11-02	International Business Machines Corporation	Coupling of conductive vias to complex power-signal substructures
US20110009960A1 (en) *	2001-11-16	2011-01-13	Allergan, Inc.	Prosthetic fabric structure
US6902932B2 (en) *	2001-11-16	2005-06-07	Tissue Regeneration, Inc.	Helically organized silk fibroin fiber bundles for matrices in tissue engineering
GB0209893D0 (en) *	2002-04-30	2002-06-05	Molmed Spa	Conjugate
GB0209896D0 (en) *	2002-04-30	2002-06-05	Molmed Spa	Conjugate
US20060020119A1 (en) *	2004-03-29	2006-01-26	Stephen Grimes	Monoclonal antibodies to gastrin hormone
WO2004088326A2 (en) *	2003-03-28	2004-10-14	Aphton Corporation	Gastrin hormone immunoassays
EP1794586B1 (de)	2004-09-22	2013-01-30	Cancer Advances, Inc.,	Monoklonale antikörper gegen progastrin
US7622438B1 (en)	2005-07-18	2009-11-24	Acologix, Inc.	Protein formulation for promoting hard tissue formation
GB2433506A (en) *	2005-12-20	2007-06-27	Sharp Kk	A method of producing a multimeric capture agent
GB2433591A (en) *	2005-12-20	2007-06-27	Sharp Kk	Method for functionalising a hydrophobic substrate
GB2433505A (en) *	2005-12-20	2007-06-27	Sharp Kk	Capture agents for binding a ligand
CN101240030B (zh) *	2007-02-07	2010-08-11	首都医科大学	正十一烷基和rgd肽构建的缀合物、它们的合成及在医学中的应用
CN101240027B (zh) *	2007-02-07	2011-04-20	首都医科大学	正壬烷基和rgd肽构建的缀合物、它们的合成及在医学中的应用
CN101240028B (zh) *	2007-02-07	2010-08-18	首都医科大学	正十五烷基和rgd肽构建的缀合物、它们的合成及在医学中的应用
CN101240029B (zh) *	2007-02-07	2010-08-11	首都医科大学	正庚烷基和rgd肽构建的缀合物、其合成方法和应用
CN101240031B (zh) *	2007-02-07	2010-10-13	首都医科大学	正十七烷基和rgd肽构建的缀合物、其制备方法及应用
US8529897B2 (en)	2007-08-16	2013-09-10	Carnegie Mellon University	Inflammation-regulating compositions and methods
US20090246248A1 (en) *	2008-03-27	2009-10-01	Affinergy	Coating compositions having improved performance
US9308070B2 (en) *	2008-12-15	2016-04-12	Allergan, Inc.	Pliable silk medical device
CN105063875A (zh)	2008-12-15	2015-11-18	阿勒根公司	制造用于假体装置的编织网的方法
US9326840B2 (en)	2008-12-15	2016-05-03	Allergan, Inc.	Prosthetic device and method of manufacturing the same
US9204954B2 (en) *	2008-12-15	2015-12-08	Allergan, Inc.	Knitted scaffold with diagonal yarn
US9204953B2 (en)	2008-12-15	2015-12-08	Allergan, Inc.	Biocompatible surgical scaffold with varying stretch
US20110052695A1 (en) *	2009-04-20	2011-03-03	Allergan, Inc.	Drug delivery platforms comprising silk fibroin hydrogels and uses thereof
US20110189292A1 (en) *	2009-04-20	2011-08-04	Allergan, Inc.	Dermal fillers comprising silk fibroin hydrogels and uses thereof
US20110111031A1 (en) *	2009-04-20	2011-05-12	Guang-Liang Jiang	Drug Delivery Platforms Comprising Silk Fibroin Hydrogels and Uses Thereof
ES2443045T5 (es) *	2009-04-20	2021-05-10	Allergan Inc	Hidrogeles de fibroína de seda y usos de éstos
CA2773956A1 (en) *	2009-09-11	2011-03-17	Allergan, Inc.	Prosthetic device and method of manufacturing the same
US12150978B2 (en)	2017-06-15	2024-11-26	Cancer Advances Inc.	Compositions and methods for preventing tumors and cancer
KR102772810B1 (ko)	2017-06-15	2025-02-28	캔서 어드밴시스 아이엔씨	종양 및 암에 대한 체액성 및 세포 면역을 유도하기 위한 조성물 및 방법
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1989
- 1989-03-20 US US07/326,168 patent/US5120829A/en not_active Expired - Lifetime
1990
- 1990-03-20 WO PCT/US1990/001486 patent/WO1990011297A1/en not_active Ceased
- 1990-03-20 ES ES90905829T patent/ES2057553T3/es not_active Expired - Lifetime
- 1990-03-20 AT AT90905829T patent/ATE109161T1/de not_active IP Right Cessation
- 1990-03-20 DE DE69011102T patent/DE69011102T2/de not_active Expired - Fee Related
- 1990-03-20 DK DK90905829.9T patent/DK0464140T3/da active
- 1990-03-20 EP EP90905829A patent/EP0464140B1/de not_active Expired - Lifetime
- 1990-03-20 JP JP2505512A patent/JP2723669B2/ja not_active Expired - Lifetime
- 1990-03-20 CA CA002046631A patent/CA2046631A1/en not_active Abandoned
1992
- 1992-08-20 US US07/932,929 patent/US5587456A/en not_active Expired - Lifetime
1995
- 1995-05-05 US US08/435,317 patent/US5591822A/en not_active Expired - Lifetime
1996
- 1996-10-10 US US08/729,980 patent/US5760176A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2046631A1 (en)	1990-09-21
US5760176A (en)	1998-06-02
WO1990011297A1 (en)	1990-10-04
EP0464140A1 (de)	1992-01-08
JP2723669B2 (ja)	1998-03-09
US5591822A (en)	1997-01-07
ES2057553T3 (es)	1994-10-16
JPH04506511A (ja)	1992-11-12
US5587456A (en)	1996-12-24
DE69011102T2 (de)	1994-11-24
DE69011102D1 (de)	1994-09-01
DK0464140T3 (da)	1994-09-05
EP0464140B1 (de)	1994-07-27
US5120829A (en)	1992-06-09

Legal Events

Date	Code	Title	Description
1995-02-15	UEP	Publication of translation of european patent specification
1998-12-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE69011102D1 (de)	1994-09-01	Hydrophobe bindungsstelle für adhäsionspeptide.
IMAJOH et al.	1986	The amino-terminal hydrophobic region of the small subunit of calcium-activated neutral protease (CANP) is essential for its activation by phosphatidylinositol
RO80806A (ro)	1983-02-01	Procedeu pentru obtinerea enzimatica a peptidelor
IL115199A (en)	2005-05-17	Composition comprising a polynucleic acid molecule in a liposome and method using said composition
ES2124295T3 (es)	1999-02-01	Expresion y purificacion de factor tisular soluble recombinante.
DK0948358T4 (da)	2012-03-19	Stabile inteferon-væskeformuleringer
BG103439A (bg)	2000-01-31	Подобрения в или във връзка с диагностични/лечебни средства
BR9808668A (pt)	2000-07-11	Suspensão aquosa de microcápsulas compreendendo um material biologicamente ativo, e, processos para preparação de uma suspensão aquosa de microcápsulas aderentes e para aplicação de microcápsulas em um substrato pretendido
ATE81135T1 (de)	1992-10-15	Aktive thymopentin-analoga.
ES2038233T3 (es)	1993-07-16	Liquidos acondicionadores de substancia dental y osea.
MY106287A (en)	1995-04-29	Acid addition salts of amidated taurine or glycine, their preparation and use
NZ504486A (en)	2003-02-28	Attaching substances to micro-organisms
DE59906362D1 (de)	2003-08-28	Verwendung von lipopeptiden oder lipoproteinen zur wundbehandlung
ATE46703T1 (de)	1989-10-15	Regionspezifische determinanten fuer vitamin-k abhaengiges knochenprotein.
IE902389L (en)	1990-12-30	Enzymatically binding bioactive materials to proteins
JPS57117868A (en)	1982-07-22	Method of combining biological active substance to carrier containing hydroxyl group
CA2008817A1 (en)	1990-08-10	M-csf monoclonal antibodies that recognize a neutralizing conformational epitope
DE59712235D1 (de)	2005-04-21	Immunologisch aktive proteine von borrelia burgdorferi, dafür kodierende nukleinsäuren sowie deren verwendung in testkits und als impfstoffe
ES8900018A1 (es)	1988-11-16	Procedimiento para la fabricacion de derivados aminoalcoholes peptidicos inhibidores de la renina y de las proteasas acidas
ATE60788T1 (de)	1991-02-15	Derivat von p-aminophenol mit mucrosekretolytischer fluessiger und antipyretischer wirksamkeit, dessen verfahren zur herstellung und dessen pharmazeutische zusammensetzungen.
DE69315730D1 (de)	1998-01-29	Verfahren zur Herstellung von Peptiden und neue Zwischenverbindungen dazu
WO1999001567A3 (en)	1999-04-01	Methods and compositions for a deubiquitinating enzyme and variants thereof
SE8200757L (sv)	1982-02-10	Biologiskt aktiva peptider
DE69428909D1 (de)	2001-12-06	Für die immun- und cns-therapie nutzbare, neuartige tripeptide
DE3585936D1 (de)	1992-06-04	Biologisch aktive peptide, deren verfahren zur herstellung und pharmazeutische zusammensetzungen.