ATE109972T1 - Beschichtungsmittel für beständige arzneizubereitungen mit verzögerter wirkstoffabgabe. - Google Patents

Beschichtungsmittel für beständige arzneizubereitungen mit verzögerter wirkstoffabgabe.

Info

Publication number: ATE109972T1
Authority: AT; Austria
Prior art keywords: glyceryl ester; acid; deca; coating; coating agent
Prior art date: 1990-02-23

Application number

AT91102524T

Other languages

English (en)

Inventor

Yohko Akiyama

Naoki Nagahara

Minoru Yoshioka

Original Assignee

Takeda Chemical Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-02-23

Filing date

1991-02-21

Publication date

1994-09-15

1991-02-21 Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd

1994-09-15 Application granted granted Critical

1994-09-15 Publication of ATE109972T1 publication Critical patent/ATE109972T1/de

Links

239000011248 coating agent Substances 0.000 title abstract 5
230000003111 delayed effect Effects 0.000 title 1
239000003814 drug Substances 0.000 title 1
125000005908 glyceryl ester group Chemical group 0.000 abstract 6
238000000576 coating method Methods 0.000 abstract 2
UKMSUNONTOPOIO-UHFFFAOYSA-N docosanoic acid Chemical compound CCCCCCCCCCCCCCCCCCCCCC(O)=O UKMSUNONTOPOIO-UHFFFAOYSA-N 0.000 abstract 2
POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 abstract 2
239000008187 granular material Substances 0.000 abstract 2
IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 abstract 2
238000002360 preparation method Methods 0.000 abstract 2
WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 abstract 1
LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 abstract 1
QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 abstract 1
235000021357 Behenic acid Nutrition 0.000 abstract 1
-1 Fatty acid esters Chemical class 0.000 abstract 1
239000005639 Lauric acid Substances 0.000 abstract 1
OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 abstract 1
239000005642 Oleic acid Substances 0.000 abstract 1
ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 abstract 1
235000021314 Palmitic acid Nutrition 0.000 abstract 1
235000021355 Stearic acid Nutrition 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
229940116226 behenic acid Drugs 0.000 abstract 1
235000014113 dietary fatty acids Nutrition 0.000 abstract 1
229930195729 fatty acid Natural products 0.000 abstract 1
239000000194 fatty acid Substances 0.000 abstract 1
QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 abstract 1
229960004232 linoleic acid Drugs 0.000 abstract 1
WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 abstract 1
QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 abstract 1
OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 abstract 1
ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 abstract 1
239000006187 pill Substances 0.000 abstract 1
229920000223 polyglycerol Polymers 0.000 abstract 1
239000007787 solid Substances 0.000 abstract 1
239000008117 stearic acid Substances 0.000 abstract 1
238000013268 sustained release Methods 0.000 abstract 1
239000012730 sustained-release form Substances 0.000 abstract 1
239000003826 tablet Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Preparation (AREA)
Paints Or Removers (AREA)

AT91102524T 1990-02-23 1991-02-21 Beschichtungsmittel für beständige arzneizubereitungen mit verzögerter wirkstoffabgabe. ATE109972T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP4282590		1990-02-23

Publications (1)

Publication Number	Publication Date
ATE109972T1 true ATE109972T1 (de)	1994-09-15

Family

ID=12646737

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91102524T ATE109972T1 (de)	1990-02-23	1991-02-21	Beschichtungsmittel für beständige arzneizubereitungen mit verzögerter wirkstoffabgabe.

Country Status (12)

Country	Link
US (1)	US5162057A (de)
EP (1)	EP0443572B1 (de)
JP (1)	JP3078859B2 (de)
KR (1)	KR910021236A (de)
AT (1)	ATE109972T1 (de)
AU (1)	AU642205B2 (de)
CA (1)	CA2036906C (de)
DE (1)	DE69103438T2 (de)
DK (1)	DK0443572T3 (de)
ES (1)	ES2057625T3 (de)
NZ (1)	NZ237193A (de)
RU (1)	RU2072836C1 (de)

Families Citing this family (52)

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EP0666709B1 (de) *	1992-10-30	1997-05-07	The Procter & Gamble Company	Unverdauliche, feste polyglycerinester-partikel enthaltende fettzusammensetzungen mit passiver ölverlustkontrolle
US5288318A (en) *	1993-07-01	1994-02-22	The United States Of America As Represented By The Secretary Of The Army	Cellulose acetate and starch based biodegradable injection molded plastics compositions and methods of manufacture
JPH07112940A (ja) *	1993-08-26	1995-05-02	Takeda Chem Ind Ltd	徐放性非経口投与製剤およびその製造方法
GB9325445D0 (en)	1993-12-13	1994-02-16	Cortecs Ltd	Pharmaceutical formulations
US5478501A (en) *	1994-04-07	1995-12-26	The Andrew Jergens Company	Bathing composition containing coated cationic polymer
DE4420516C2 (de) *	1994-06-13	1998-10-22	Henkel Kgaa	Polyglycerinpolyhydroxystearate
US5494502A (en) *	1994-10-03	1996-02-27	The Chemmark Corporation	Asphalt release agent
US5531681A (en) *	1995-01-13	1996-07-02	Abbott Laboratories	Apparatus for altering composition of nutritional product during enteral tube feeding
US5533973A (en) *	1995-01-13	1996-07-09	Abbott Laboratories	Alteration of nutritional product during enteral tube feeding
DE19619636A1 (de) *	1996-05-15	1997-11-20	Basf Ag	Latent vernetzende wässerige Polyurethandispersionen
FR2753904B1 (fr) *	1996-10-01	1998-10-30	Gattefosse Ets Sa	Composition pharmaceutique a liberation modifiee de principe actif, comportant une matrice, et procede de fabrication
AU6422798A (en) *	1997-03-25	1998-10-20	Takeda Chemical Industries Ltd.	Stabilized urease inhibitor
DE19726264A1 (de) *	1997-06-20	1998-12-24	Sueddeutsche Kalkstickstoff	Verfahren zur Herstellung homogener, Monoglyceride und polare oder unpolare Substanzen enthaltender wasserfreier Formulierungen
US5891476A (en) *	1997-12-22	1999-04-06	Reo; Joe P.	Tastemasked pharmaceutical system
US6080132A (en) *	1998-02-27	2000-06-27	Abbott Laboratories	Apparatus for altering characteristics of a fluid
JP3466921B2 (ja) *	1998-06-03	2003-11-17	大塚製薬株式会社	味マスキング医薬製剤
US6309373B1 (en)	1998-08-12	2001-10-30	Abbott Laboratories	Apparatus for altering the characteristics of a fluid
DE19842753A1 (de) *	1998-09-18	2000-03-23	Bayer Ag	Agitationsunabhängige pharmazeutische Retardzubereitungen und Verfahren zu ihrer Herstellung
HUP0104606A3 (en) *	1998-12-18	2003-01-28	Basf Ag	A pharmaceutical mixture comprising a profen
US6723342B1 (en)	1999-02-08	2004-04-20	Fmc Corporation	Edible coating composition
US6432448B1 (en)	1999-02-08	2002-08-13	Fmc Corporation	Edible coating composition
EP1949890A3 (de)	1999-06-04	2011-05-18	ALZA Corporation	Implantierbare Gelzusammensetzungen und Herstellungsverfahren dafür
EP1183010A2 (de) *	1999-06-04	2002-03-06	ALZA Corporation	Implantierbare gel zusammensetzung und verfahren zur herstellung
US6251432B1 (en) *	1999-07-01	2001-06-26	Abbott Laboratories	Sustained release dosage form unit having latex coating and method of making the same
US6500462B1 (en)	1999-10-29	2002-12-31	Fmc Corporation	Edible MCC/PGA coating composition
FR2805462B1 (fr) *	2000-02-24	2003-08-15	Therabel Res	Nouvelle forme galenique orale a liberation prolongee de la molsidomine
US7829100B2 (en) *	2000-09-12	2010-11-09	Teagarden Dirk L	Pharmaceutical composition having modified carrier
FR2816507B1 (fr)	2000-11-16	2003-02-28	Ethypharm Lab Prod Ethiques	Microgranules a base de principe actif, procede de fabrication et compositons pharmaceutiques integrant lesdits microgranules
AU2002225763A1 (en)	2000-11-28	2002-06-11	Fmc Corporation	Edible pga(propylene glycol alginate) coating composition
US6932861B2 (en)	2000-11-28	2005-08-23	Fmc Corporation	Edible PGA coating composition
ES2187380A1 (es) *	2001-11-16	2003-06-01	Sanchez Juan Balufo	Mejoras introducidas en productos destinados al consumo humano o animal.
EP1490031A1 (de) *	2002-03-07	2004-12-29	Vectura Limited	Schnell schmelzende multiteilchen-formulierungen für die orale abgabe
US20040096498A1 (en) *	2002-04-29	2004-05-20	Alvin Kershman	Oral pharmaceutical delivery system with improved sustained release
JP4312423B2 (ja) *	2002-06-14	2009-08-12	ピジョン株式会社	腸溶性カプセル剤
US7659061B2 (en) *	2002-11-19	2010-02-09	Pharmacia & Upjohn Company	Pharmaceutical compositions having a modified vehicle
DE10315640A1 (de) *	2003-04-04	2004-10-14	Ignatov, Konstantin	Verfahren zur kontrollierten Freisetzung von Komponenten in eine Lösung
CN1812793A (zh)	2003-06-27	2006-08-02	大塚制药株式会社	药物持续释放颗粒及其制备方法
RU2240120C1 (ru) *	2003-07-14	2004-11-20	ЗАО "Канонфарма продакшн"	Фармацевтический состав для улучшения мозгового кровообращения (винпомакс) и способ его получения
RU2261095C1 (ru) *	2004-01-09	2005-09-27	Закрытое акционерное общество "Фармацевтическое предприятие "Оболенское"	Лекарственная форма, обладающая нестероидным противовоспалительным действием, и способ ее изготовления
GB0423964D0 (en) *	2004-10-28	2004-12-01	Jagotec Ag	Dosage form
US20060240194A1 (en) *	2005-04-26	2006-10-26	Cargill, Incorporated	Polyglycerol fatty acid ester composition and coating
TWI274889B (en) *	2005-10-06	2007-03-01	Elan Microelectronics Corp	Resistive touch screen measurement system
JP5069417B2 (ja) *	2006-03-20	2012-11-07	三菱商事フードテック株式会社	フィルムコーティング層とフィルムコーティング製品及びその製造方法
JP5301273B2 (ja) *	2006-08-09	2013-09-25	田辺三菱製薬株式会社	錠剤
US8257749B2 (en) *	2007-02-08	2012-09-04	Biolargo Life Technologies, Incorporated	Systems providing at least pesticidal activity
US8491937B2 (en) *	2007-02-15	2013-07-23	Wyeth Llc	Stability in vitamin and mineral supplements
US8227399B2 (en) *	2010-02-12	2012-07-24	Evonik Goldschmidt Gmbh	Polyglycerol esters and their use
JP5226097B2 (ja)	2011-03-30	2013-07-03	株式会社ファンケル	サプリメントを内包する蓋体とサプリメント分散媒を充填したボトルからなるボトル入り飲料
JP5308583B1 (ja) *	2012-03-29	2013-10-09	株式会社ファンケル	ボトル飲料
JP7039197B2 (ja) *	2017-06-30	2022-03-22	小林製薬株式会社	Ｓ／ｏ型サスペンション及びその製造方法
US12274795B2 (en) *	2018-10-22	2025-04-15	Ioi Oleo Gmbh	Coating material for use in an HMC method

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US3097144A (en) *	1960-10-14	1963-07-09	Upjohn Co	Heat-cured, polymeric, medicinal dosage film coatings containing a polyvinylpyrrolidone copolymer, polyethenoid acid, and polyethylene glycol
US3244596A (en) *	1962-10-18	1966-04-05	Univ Iowa College Of Pharmacy	Coated medicinal agents and coating compositions therefor
US3914131A (en) *	1971-08-23	1975-10-21	Emery Industries Inc	Useful wax compositions
JPS5966844A (ja) *	1982-10-12	1984-04-16	Riken Vitamin Co Ltd	養魚用生餌飼料組成物
JPS6112632A (ja) *	1984-06-27	1986-01-21	Eisai Co Ltd	脂溶性薬剤含有組成物
JPS6156050A (ja) *	1984-08-23	1986-03-20	Asahi Denka Kogyo Kk	冷凍食品
FI77573C (fi) *	1987-05-08	1989-04-10	Orion Yhtymae Oy	Ny konsistens.

1991
- 1991-02-15 JP JP03044198A patent/JP3078859B2/ja not_active Expired - Fee Related
- 1991-02-18 AU AU71146/91A patent/AU642205B2/en not_active Ceased
- 1991-02-21 DE DE69103438T patent/DE69103438T2/de not_active Expired - Fee Related
- 1991-02-21 DK DK91102524.5T patent/DK0443572T3/da active
- 1991-02-21 EP EP91102524A patent/EP0443572B1/de not_active Expired - Lifetime
- 1991-02-21 ES ES91102524T patent/ES2057625T3/es not_active Expired - Lifetime
- 1991-02-21 AT AT91102524T patent/ATE109972T1/de not_active IP Right Cessation
- 1991-02-22 RU SU914894891A patent/RU2072836C1/ru active
- 1991-02-22 US US07/659,610 patent/US5162057A/en not_active Expired - Lifetime
- 1991-02-22 NZ NZ237193A patent/NZ237193A/en unknown
- 1991-02-22 CA CA002036906A patent/CA2036906C/en not_active Expired - Fee Related
- 1991-02-23 KR KR1019910002979A patent/KR910021236A/ko not_active Abandoned

Also Published As

Publication number	Publication date
JP3078859B2 (ja)	2000-08-21
CA2036906A1 (en)	1991-08-24
CA2036906C (en)	2002-01-22
JPH05310599A (ja)	1993-11-22
DE69103438T2 (de)	1994-11-24
NZ237193A (en)	1994-09-27
AU642205B2 (en)	1993-10-14
EP0443572B1 (de)	1994-08-17
DK0443572T3 (da)	1994-09-19
ES2057625T3 (es)	1994-10-16
AU7114691A (en)	1991-09-12
EP0443572A1 (de)	1991-08-28
US5162057A (en)	1992-11-10
RU2072836C1 (ru)	1997-02-10
KR910021236A (ko)	1991-12-20
DE69103438D1 (de)	1994-09-22

Legal Events

Date	Code	Title	Description
1995-03-15	UEP	Publication of translation of european patent specification
1999-11-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE109972T1 (de)	1994-09-15	Beschichtungsmittel für beständige arzneizubereitungen mit verzögerter wirkstoffabgabe.
HUT57541A (en)	1991-12-30	Fungicidal compositions comprising substituted acrylic acid esters as active ingredient and process for producing the active ingredients
NZ231281A (en)	1991-01-29	Sustained release pharmaceutical preparations comprising the active agent dispersed in a solid matrix of a fatty acid ester of a polyglycerol
NZ224278A (en)	1990-09-26	Ibuprofen sustained release tablet and process
ATE180668T1 (de)	1999-06-15	S(+)-ibuprofen enthaltende arzneimittel
IL111519A (en)	2000-12-06	Sustained release tablets containing acetaminophen and methods for the preparation thereof
ES2153355T3 (es)	2001-03-01	Procedimiento para la preparacion de microesferas que contienen compuestos biologicamente activos.
MD872G2 (ro)	1998-08-31	Compoziţie farmaceutică efervescentă şi preparat pe baza ei, procedeu de fabricare a preparatului
GB1296505A (de)	1972-11-15
ES2140467T3 (es)	2000-03-01	Procedimiento para la obtencion de granulados tensioactivos.
KR960702322A (ko)	1996-04-27	활성성분으로서의 디클로로메틸렌디포스폰산을 함유하며 약효가 개선된 정제 (more easily biologically absorbed tablet containing dichloromethylene diphosphonic acid as the active agent)
HUT51105A (en)	1990-04-28	Pesticide comprising substituted acrylic acid ester derivatives as active ingredient and process for producing the active ingredients
GR3021320T3 (en)	1997-01-31	High-content ibuprofen lysinate pharmaceutical formulation
ES8800040A1 (es)	1987-10-16	Procedimiento para la obtencion de una composicion farmaceutica de liberacion retardada a base de 9,10-dihidro-alcaloides.
HUT52388A (en)	1990-07-28	Process for producing pharmaceutical compositions comprising unsaturated fatty acids and selenium as active ingredient
EP0427396A3 (en)	1992-02-26	Optically active fluorine-containing 3-hydroxybutyric acid esters and process for producing same
JPS5640606A (en)	1981-04-16	Preparation of stable drug
ZA9110055B (en)	1992-09-30	Process for the preparation of optically active esters of quinoxalinyloxyphenoxypropionic acid
HUT47895A (en)	1989-04-28	Insecticide and acaricide composition containing substituted phenyl-acetic acid ester derivatives as active components and process for producing the active components
NZ226696A (en)	1991-10-25	Tablet composition comprising a phthalazine acetic acid derivative as the active ingredient present in from 83-88 wt%
MORITA et al.	1987	Effect of L-Ascorbic Acid and L-Ascorbyl Palmitate on the Peroxidation of Linoleic Acid: Relationship between Appearance of Reaction Mixture and Peroxidation of Linoleic Acid
HU179068B (en)	1982-08-28	Herbicide compositions containing esters of carbanilidic acid derivatives and process for producing the active agents
JPS5225379A (en)	1977-02-25	Three-dimensional automtic wrehouse having fumigating chamber
PL287608A1 (en)	1992-09-21	Method of obtaining stable nitroglycerin dispersion in production of pharmaceutical preparations in particular in the form of tablets