ATE111706T1 - Verfahren und gerät zur messung des blut-glukose- gehaltes in vivo. - Google Patents

Verfahren und gerät zur messung des blut-glukose- gehaltes in vivo.

Info

Publication number
ATE111706T1
ATE111706T1 AT91911126T AT91911126T ATE111706T1 AT E111706 T1 ATE111706 T1 AT E111706T1 AT 91911126 T AT91911126 T AT 91911126T AT 91911126 T AT91911126 T AT 91911126T AT E111706 T1 ATE111706 T1 AT E111706T1
Authority
AT
Austria
Prior art keywords
chambers
substance
vivo
infrared light
absorption
Prior art date
Application number
AT91911126T
Other languages
English (en)
Inventor
Vaughan Clift
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of ATE111706T1 publication Critical patent/ATE111706T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6848—Needles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/314—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1702—Systems in which incident light is modified in accordance with the properties of the material investigated with opto-acoustic detection, e.g. for gases or analysing solids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G01N21/553—Attenuated total reflection and using surface plasmons

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Optics & Photonics (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT91911126T 1990-06-06 1991-06-06 Verfahren und gerät zur messung des blut-glukose- gehaltes in vivo. ATE111706T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPK048990 1990-06-06
AUPK431091 1991-01-22

Publications (1)

Publication Number Publication Date
ATE111706T1 true ATE111706T1 (de) 1994-10-15

Family

ID=25643880

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91911126T ATE111706T1 (de) 1990-06-06 1991-06-06 Verfahren und gerät zur messung des blut-glukose- gehaltes in vivo.

Country Status (5)

Country Link
EP (1) EP0536187B1 (de)
JP (1) JP3212996B2 (de)
AT (1) ATE111706T1 (de)
DE (1) DE69104203T2 (de)
WO (1) WO1991018548A1 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5582184A (en) 1993-10-13 1996-12-10 Integ Incorporated Interstitial fluid collection and constituent measurement
SE9500893D0 (sv) * 1995-03-13 1995-03-13 Synectics Medical Ab Förfarande och system för bestämning av substanssammansättning jämte ambulatoriskt registreringssystem
US5879310A (en) * 1995-09-08 1999-03-09 Integ, Inc. Body fluid sampler
US6614522B1 (en) 1995-09-08 2003-09-02 Integ, Inc. Body fluid sampler
US6624882B2 (en) 1995-09-08 2003-09-23 Integ, Inc. Methods of sampling body fluid
US5879367A (en) 1995-09-08 1999-03-09 Integ, Inc. Enhanced interstitial fluid collection
US5891022A (en) * 1996-09-25 1999-04-06 Ohmeda Inc. Apparatus for performing multiwavelength photoplethysmography
WO1998019159A1 (en) 1996-10-30 1998-05-07 Mercury Diagnostics, Inc. Synchronized analyte testing system
JP4212007B2 (ja) * 1996-11-26 2009-01-21 パナソニック電工株式会社 血液成分濃度の分析装置
ES2227880T3 (es) 1997-08-09 2005-04-01 Roche Diagnostics Gmbh Dispositivo de analisis para realizar analisis in vivo en el cuerpo de un paciente.
US5941821A (en) * 1997-11-25 1999-08-24 Trw Inc. Method and apparatus for noninvasive measurement of blood glucose by photoacoustics
DE19858426C2 (de) * 1997-12-17 2002-01-31 Steffen Leonhardt Vorrichtung zur Messung des menschlichen Blutzuckerspiegels
US6226082B1 (en) 1998-06-25 2001-05-01 Amira Medical Method and apparatus for the quantitative analysis of a liquid sample with surface enhanced spectroscopy
US6120464A (en) * 1998-10-16 2000-09-19 Integ, Inc. Needle assembly for fluid sampler
US6368563B1 (en) 1999-03-12 2002-04-09 Integ, Inc. Collection well for body fluid tester
JP3594534B2 (ja) 1999-04-30 2004-12-02 ヘルマン ファウ、リリエンフェルトアル 物質を検出する装置
EP1194069B1 (de) 1999-07-08 2006-03-22 Steffen Dr.-Ing. Leonhardt Vorrichtung zur messung des menschlichen blutzuckerspiegels
US7050157B2 (en) * 2001-11-08 2006-05-23 Optiscan Biomedical Corp. Reagent-less whole-blood glucose meter
EP1585440A1 (de) * 2003-01-13 2005-10-19 Glucon Inc. Photoakustische prüfungsmethode und vorrichtung
US6968222B2 (en) 2003-05-02 2005-11-22 Oculir, Inc. Methods and device for non-invasive analyte measurement
US6958039B2 (en) 2003-05-02 2005-10-25 Oculir, Inc. Method and instruments for non-invasive analyte measurement
US6975892B2 (en) 2003-10-21 2005-12-13 Oculir, Inc. Methods for non-invasive analyte measurement from the conjunctiva
WO2005007215A2 (en) 2003-07-09 2005-01-27 Glucolight Corporation Method and apparatus for tissue oximetry
WO2005027746A1 (ja) * 2003-09-22 2005-03-31 Matsushita Electric Industrial Co., Ltd. グルコース濃度測定方法及びグルコース濃度測定装置
US7510849B2 (en) 2004-01-29 2009-03-31 Glucolight Corporation OCT based method for diagnosis and therapy
US8036727B2 (en) 2004-08-11 2011-10-11 Glt Acquisition Corp. Methods for noninvasively measuring analyte levels in a subject
US7254429B2 (en) 2004-08-11 2007-08-07 Glucolight Corporation Method and apparatus for monitoring glucose levels in a biological tissue
CA2604653A1 (en) 2005-04-13 2006-10-19 Glucolight Corporation Method for data reduction and calibration of an oct-based blood glucose monitor
EP2026058A4 (de) 2006-06-08 2009-12-30 Omron Healthcare Co Ltd Messvorrichtung für eine biologische komponente mit fähigkeit zur genauen nichtinvasiven messung der biologischen komponente
JP2008026036A (ja) * 2006-07-18 2008-02-07 Aloka Co Ltd 含有物測定装置
ATE492796T1 (de) * 2006-09-20 2011-01-15 Prad Res & Dev Nv Vorrichtung und verfahren zur optischen ermittlung der anwesenheit von kohlendioxid
JP2008275383A (ja) * 2007-04-26 2008-11-13 Hitachi Engineering & Services Co Ltd 混合成分系の濃度測定方法及び装置、及びその装置を用いた省エネルギー或いは排気浄化設備の運転制御システム。
US8390817B2 (en) * 2008-01-03 2013-03-05 Koninklijke Philips Electronics N.V. Evanescent field modulation in a biosensor
US8768423B2 (en) 2008-03-04 2014-07-01 Glt Acquisition Corp. Multispot monitoring for use in optical coherence tomography
KR101603357B1 (ko) 2008-04-24 2016-03-14 아크레이 가부시키가이샤 혈당치 제어 시스템
DE102015007871B4 (de) * 2014-08-09 2022-10-20 SAMTD GmbH & Co. KG Verfahren und Vorrichtung zur nicht-invasiven Bestimmung einer Messgröße eines Analyten in einem biologischen Körper
CN108872082B (zh) * 2018-04-03 2021-03-02 深圳大学 光声显微成像系统及方法
CN119174605A (zh) * 2023-06-21 2024-12-24 Oppo广东移动通信有限公司 采集装置、血糖仪和血糖检测方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2934190A1 (de) * 1979-08-23 1981-03-19 Müller, Gerhard, Prof. Dr.-Ing., 7080 Aalen Verfahren und vorrichtung zur molekuelspektroskopie, insbesondere zur bestimmung von stoffwechselprodukten
US4509522A (en) * 1981-12-15 1985-04-09 The United States Of America As Represented By The Secretary Of The Navy Infrared optical measurement of blood gas concentrations and fiber optic catheter
US4655225A (en) 1985-04-18 1987-04-07 Kurabo Industries Ltd. Spectrophotometric method and apparatus for the non-invasive
US4882492A (en) * 1988-01-19 1989-11-21 Biotronics Associates, Inc. Non-invasive near infrared measurement of blood analyte concentrations

Also Published As

Publication number Publication date
WO1991018548A1 (en) 1991-12-12
EP0536187B1 (de) 1994-09-21
JP3212996B2 (ja) 2001-09-25
JPH05507866A (ja) 1993-11-11
EP0536187A1 (de) 1993-04-14
DE69104203D1 (de) 1994-10-27
DE69104203T2 (de) 1995-01-19

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