ATE111740T1 - Menschlicher nervenwachstumsfaktor. - Google Patents

Menschlicher nervenwachstumsfaktor.

Info

Publication number
ATE111740T1
ATE111740T1 AT89400693T AT89400693T ATE111740T1 AT E111740 T1 ATE111740 T1 AT E111740T1 AT 89400693 T AT89400693 T AT 89400693T AT 89400693 T AT89400693 T AT 89400693T AT E111740 T1 ATE111740 T1 AT E111740T1
Authority
AT
Austria
Prior art keywords
growth factor
nerve growth
ngf
human nerve
purification
Prior art date
Application number
AT89400693T
Other languages
English (en)
Inventor
Valle Francesco Dr Della
Lanfranco Dr Callegaro
Silvana Lorenzi
Original Assignee
Fidia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Spa filed Critical Fidia Spa
Application granted granted Critical
Publication of ATE111740T1 publication Critical patent/ATE111740T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/48—Nerve growth factor [NGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/85—Reproductive organs or embryos
    • Y10S530/851—Placenta; amniotic fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Hospice & Palliative Care (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT89400693T 1988-03-18 1989-03-14 Menschlicher nervenwachstumsfaktor. ATE111740T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT47745/88A IT1219874B (it) 1988-03-18 1988-03-18 Utilizzazione del fattore di crescita nervoso umano e sue composizioni farmaceutiche

Publications (1)

Publication Number Publication Date
ATE111740T1 true ATE111740T1 (de) 1994-10-15

Family

ID=11262248

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89400693T ATE111740T1 (de) 1988-03-18 1989-03-14 Menschlicher nervenwachstumsfaktor.

Country Status (10)

Country Link
US (1) US5210185A (de)
EP (1) EP0333574B1 (de)
JP (1) JP2798413B2 (de)
AT (1) ATE111740T1 (de)
AU (1) AU627717B2 (de)
CA (1) CA1339791C (de)
DE (1) DE68918312T2 (de)
DK (1) DK129089A (de)
IT (1) IT1219874B (de)
ZA (1) ZA891962B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5180820A (en) * 1989-08-30 1993-01-19 Barde Yves Alain Brain-derived neurotrophic factor
US5624898A (en) 1989-12-05 1997-04-29 Ramsey Foundation Method for administering neurologic agents to the brain
US6407061B1 (en) 1989-12-05 2002-06-18 Chiron Corporation Method for administering insulin-like growth factor to the brain
IT1239270B (it) * 1990-02-27 1993-10-01 Fidia Spa Metodo per la determinazione quantitativa della forma biologicamente attiva del fattore di crescita nervoso umano in liquidi proteici
US5986070A (en) * 1990-04-06 1999-11-16 Amgen Inc. Production of biologically active NGF proteins
US5235043A (en) * 1990-04-06 1993-08-10 Synergen, Inc. Production of biologically active, recombinant members of the ngf/bdnf family of neurotrophic proteins
JPH04119399A (ja) * 1990-09-11 1992-04-20 Kenwood Corp カラオケ装置
GB9111885D0 (en) * 1991-06-03 1991-07-24 Erba Carlo Spa Nerve growth factor for use in the prevention and treatment of viral infections
US5389529A (en) * 1991-06-12 1995-02-14 Regeneron Pharmaceuticals, Inc. Modified lamβ signal sequence and processes for producing recombinant neurotrophins
US5885584A (en) * 1991-08-05 1999-03-23 Boehringer Mannheim Gmbh Regeneration of oligodendrocytes
CH684741A5 (de) * 1992-06-11 1994-12-15 Lucchini Lab Sa Verfahren zur Herstellung eines Extraktes.
RU2073518C1 (ru) * 1993-06-17 1997-02-20 Совместное русско-американское акционерное общество закрытого типа "Неофарм" Средство, восстанавливающее функцию сетчатой оболочки глаза
US6277828B1 (en) * 1993-08-20 2001-08-21 Syntex (U.S.A.) Inc. Pharmaceutical formulations of nerve growth factor
US6964947B1 (en) * 1995-11-07 2005-11-15 Genentech, Inc. Stabilizing formulation for NGF
US6090781A (en) * 1996-11-06 2000-07-18 Genentech, Inc. Stabilizing formulation for NGF
BR9713055A (pt) 1996-11-15 2000-04-04 Genentech Inc Processo para isolar uma neurotrofina humana recombinante, composição de neurotrofina e processo para purificar uma neurotrofina
US7282482B2 (en) 1998-04-08 2007-10-16 The Regents Of The University Of California NGF for the prevention of demyelination in the nervous system
CN1260249C (zh) 1998-05-06 2006-06-21 基因技术股份有限公司 用离子交换层析纯化蛋白质
US7273618B2 (en) 1998-12-09 2007-09-25 Chiron Corporation Method for administering agents to the central nervous system
EP1305040B1 (de) 2000-07-28 2009-09-09 Christopher J. Murphy Medium für transplantat
MXPA04001831A (es) 2001-08-29 2004-07-08 Neose Technologies Inc Nuevos derivados sinteticos de gangliosidos y composiciones de los mismos.
NZ567841A (en) 2003-03-06 2010-01-29 Seneb Biosciences Inc Methods and compositions for the enzymatic synthesis of gangliosides
US20070207209A1 (en) * 2004-08-27 2007-09-06 Murphy Christopher J Trophic factor combinations for nervous system treatment
EP3441402A1 (de) 2007-10-30 2019-02-13 Genentech, Inc. Antikörperreinigung durch kationenaustauschchromatographie
WO2010111530A1 (en) 2009-03-25 2010-09-30 Seneb Biosciences, Inc. Glycolipids as treatment for disease
IT201700066486A1 (it) * 2017-06-15 2018-12-15 Azienda Ospedaliero Univ Policlinico S Orsola Malpighi Bologn A Siero sanguigno per uso nel trattamento di patologie neurodegenerative oftalmologiche

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4185095A (en) * 1977-11-23 1980-01-22 The Massachusetts General Hospital Nerve growth factor
US4407744A (en) * 1977-11-23 1983-10-04 Young David M Process for obtaining nerve growth factor
US4659696A (en) * 1982-04-30 1987-04-21 Takeda Chemical Industries, Ltd. Pharmaceutical composition and its nasal or vaginal use
DK161152C (da) * 1983-03-03 1991-11-11 Genentech Inc Polypeptid med egenskaber som human beta-nervevaekstfaktor og fremgangsmaade til fremstilling deraf, dna-isolat omfattende en sekvens som koder for polypeptidet, replicerbar udtrykkelsesvektor for dna-sekvensen, rekombinant vaertscelle transformeret med vektoren, farmaceutisk praeparat indeholdende polypeptidet og fremg. der omfatter anvendelsen af polypeptidet til fremst. af et farmaceutisk praeparat
EP0121388B1 (de) * 1983-03-30 1990-06-13 Lilly Industries Limited Immunoglobulinkonjugate
US4662884A (en) * 1984-04-25 1987-05-05 University Of Utah Research Foundation Prostheses and methods for promoting nerve regeneration
IL83398A0 (en) * 1986-08-07 1987-12-31 Fidia Spa Novel neuronotrophic factor

Also Published As

Publication number Publication date
EP0333574A2 (de) 1989-09-20
DK129089D0 (da) 1989-03-16
US5210185A (en) 1993-05-11
AU627717B2 (en) 1992-09-03
ZA891962B (en) 1989-11-29
JP2798413B2 (ja) 1998-09-17
IT8847745A0 (it) 1988-03-18
CA1339791C (en) 1998-03-31
DE68918312D1 (de) 1994-10-27
DK129089A (da) 1989-09-19
EP0333574A3 (en) 1990-05-30
AU3143589A (en) 1989-09-21
JPH0228199A (ja) 1990-01-30
IT1219874B (it) 1990-05-24
DE68918312T2 (de) 1995-03-16
EP0333574B1 (de) 1994-09-21

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties