ATE112685T1 - Formulierung von menschlichen wachstumshormonen. - Google Patents

Formulierung von menschlichen wachstumshormonen.

Info

Publication number
ATE112685T1
ATE112685T1 AT89904428T AT89904428T ATE112685T1 AT E112685 T1 ATE112685 T1 AT E112685T1 AT 89904428 T AT89904428 T AT 89904428T AT 89904428 T AT89904428 T AT 89904428T AT E112685 T1 ATE112685 T1 AT E112685T1
Authority
AT
Austria
Prior art keywords
formulation
growth hormone
human growth
image
poloxamer
Prior art date
Application number
AT89904428T
Other languages
English (en)
Inventor
Rodney Pearlman
James C Oeswein
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22667706&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE112685(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE112685T1 publication Critical patent/ATE112685T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
AT89904428T 1988-04-15 1989-03-28 Formulierung von menschlichen wachstumshormonen. ATE112685T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/182,262 US5096885A (en) 1988-04-15 1988-04-15 Human growth hormone formulation

Publications (1)

Publication Number Publication Date
ATE112685T1 true ATE112685T1 (de) 1994-10-15

Family

ID=22667706

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89904428T ATE112685T1 (de) 1988-04-15 1989-03-28 Formulierung von menschlichen wachstumshormonen.

Country Status (9)

Country Link
US (1) US5096885A (de)
EP (2) EP0409870B1 (de)
JP (1) JP2747073B2 (de)
AT (1) ATE112685T1 (de)
AU (1) AU627174B2 (de)
CA (1) CA1329543C (de)
DE (1) DE68918853T2 (de)
NZ (1) NZ228747A (de)
WO (1) WO1989009614A1 (de)

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US6326154B1 (en) * 1990-11-19 2001-12-04 Genentech, Inc. Ligand-mediated immunofunctional hormone binding protein assay method
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US5492891A (en) * 1991-09-05 1996-02-20 Novo Nordisk A/S Method for treatment of patients with chronic liver disease
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Also Published As

Publication number Publication date
WO1989009614A1 (en) 1989-10-19
DE68918853D1 (de) 1994-11-17
US5096885A (en) 1992-03-17
JP2747073B2 (ja) 1998-05-06
JPH03503764A (ja) 1991-08-22
DE68918853T2 (de) 1995-04-13
AU3368789A (en) 1989-11-03
EP0603159A3 (de) 1995-12-13
EP0409870B1 (de) 1994-10-12
EP0603159A2 (de) 1994-06-22
EP0409870A1 (de) 1991-01-30
NZ228747A (en) 1991-09-25
AU627174B2 (en) 1992-08-20
CA1329543C (en) 1994-05-17

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UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time