ATE113278T1 - Zwischenprodukte für chelatbildende wirkstoffe mit vorherbestimmter symmetrie und verfahren zu ihrer herstellung. - Google Patents

Zwischenprodukte für chelatbildende wirkstoffe mit vorherbestimmter symmetrie und verfahren zu ihrer herstellung.

Info

Publication number: ATE113278T1
Authority: AT; Austria
Prior art keywords: chelating agents; manufacture; pct; intermediate products; predetermined symmetry
Prior art date: 1990-08-29

Application number

AT91914890T

Other languages

English (en)

Inventor

Fulvio Uggeri

Pier Lucio Anelli

Marcella Murru

Mario Virtuani

Original Assignee

Bracco Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-29

Filing date

1991-08-14

Publication date

1994-11-15

1991-08-14 Application filed by Bracco Spa filed Critical Bracco Spa

1994-11-15 Application granted granted Critical

1994-11-15 Publication of ATE113278T1 publication Critical patent/ATE113278T1/de

Links

239000002738 chelating agent Substances 0.000 title abstract 2
239000013067 intermediate product Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
239000000543 intermediate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

AT91914890T 1990-08-29 1991-08-14 Zwischenprodukte für chelatbildende wirkstoffe mit vorherbestimmter symmetrie und verfahren zu ihrer herstellung. ATE113278T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT02131890A IT1243801B (it)	1990-08-29	1990-08-29	Intermedi per agenti chelanti con simmetria prefissata, e procedimentoper la loro preparazione

Publications (1)

Publication Number	Publication Date
ATE113278T1 true ATE113278T1 (de)	1994-11-15

Family

ID=11180039

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91914890T ATE113278T1 (de)	1990-08-29	1991-08-14	Zwischenprodukte für chelatbildende wirkstoffe mit vorherbestimmter symmetrie und verfahren zu ihrer herstellung.

Country Status (13)

Country	Link
US (1)	US5424423A (de)
EP (1)	EP0545983B1 (de)
JP (1)	JP3119872B2 (de)
KR (1)	KR930701419A (de)
AT (1)	ATE113278T1 (de)
AU (1)	AU650903B2 (de)
CA (1)	CA2090433A1 (de)
DE (2)	DE69104842T2 (de)
DK (1)	DK0545983T3 (de)
ES (1)	ES2041617T3 (de)
GR (1)	GR930300084T1 (de)
IT (1)	IT1243801B (de)
WO (1)	WO1992004336A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5539105A (en) *	1990-08-29	1996-07-23	Dibra S.P.A.	Intermediates for chelating agents with prefixed symmetry and process for their preparation
US6875864B2 (en)	1991-08-01	2005-04-05	Bracco International B.V.	Aminocarboxylate ligands having substituted aromatic amide moieties
DE4237943C2 (de) *	1992-11-06	1997-10-23	Schering Ag	Verfahren zur Herstellung von Metallkomplexen der N-beta-Hydroxyalkyl-tri-N-carboxyalkyl-1,4,7,10-tetraazacyclododecan- und N-beta-Hydroxyalkyl-tri-N-carboxyalkyl-1,4,8,11-tetraazacyclotetradecan-Derivate
US5410043A (en) *	1991-12-06	1995-04-25	Schering Aktiengesellschaft	Process for the production of mono-N-substituted tetraaza macrocycles
DE4218744C2 (de) *	1992-06-04	1997-11-06	Schering Ag	Verfahren zur Herstellung von N-ß-Hxdroxyalkyl-tri-N-carboxylalkyl-1,4,7,10-tetraazacyclododecan- und N-ß-Hydroxyalkyl-tri-N-carboxyalkyl-1,4,8,11-tetraazacyclotetradecan-Derivaten und deren Metallkomplexe
EP0588229A3 (en) *	1992-09-12	1994-06-15	Hoechst Ag	Macrocyclic chelating agents for the preparation of technetium or rhenium complexes
JP3878208B2 (ja) *	1994-04-08	2007-02-07	ブラッコインターナショナルベスローテンフェンノートシャップ	芳香族アミド化合物およびそれらのキレート
US6693190B1 (en)	1994-05-11	2004-02-17	Bracco International B.V.	Enhanced relaxivity monomeric and multimeric compounds
FR2725449B1 (fr) *	1994-10-05	1996-12-27	Air Liquide	Derives de polyazacycloalcanes, leurs complexes metalliques et produits pharmaceutiques incorporant ces complexes
GB9504922D0 (en) *	1995-03-10	1995-04-26	Nycomed As	Process
GB9504910D0 (en) *	1995-03-10	1995-04-26	Nycomed Imaging As	Compounds
IT1292130B1 (it) *	1997-06-11	1999-01-25	Bracco Spa	Processo per la preparazione dell'acido 1,4,7,10-tetraazaciclododecan -1,4,7-triacetico e suoi derivati

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3932451A (en)	1973-11-27	1976-01-13	E. I. Du Pont De Nemours & Company	1,4,7,10-Tetraazatetracyclo[5.5.1.04,13.010,13 ]tridecane and its conjugate acids
US3979379A (en) *	1975-04-25	1976-09-07	The United States Of America As Represented By The Secretary Of The Army	Process for producing 1,3,5,7-tetraalkanoyl-1,3,5,7-octahydrotetrazocines
US4085106A (en) *	1976-01-07	1978-04-18	E. I. Du Pont De Nemours And Company	Bicyclic and tricyclic trisaminomethanes
JPS53144593A (en) *	1977-05-19	1978-12-15	Iwao Tabuse	Alklycyclum
JPS5672070A (en) *	1979-11-14	1981-06-16	Iwao Tabuse	Preparation of uranyl ion trapping agent
US4885363A (en) *	1987-04-24	1989-12-05	E. R. Squibb & Sons, Inc.	1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
US5247077A (en) *	1989-06-23	1993-09-21	Celltech Limited	Tri-aza macrocycles and processes for their preparation

1990
- 1990-08-29 IT IT02131890A patent/IT1243801B/it active IP Right Grant
1991
- 1991-08-14 DE DE69104842T patent/DE69104842T2/de not_active Expired - Fee Related
- 1991-08-14 US US08/030,007 patent/US5424423A/en not_active Expired - Fee Related
- 1991-08-14 ES ES91914890T patent/ES2041617T3/es not_active Expired - Lifetime
- 1991-08-14 AU AU84125/91A patent/AU650903B2/en not_active Ceased
- 1991-08-14 JP JP03513884A patent/JP3119872B2/ja not_active Expired - Fee Related
- 1991-08-14 AT AT91914890T patent/ATE113278T1/de active
- 1991-08-14 DE DE91914890T patent/DE545983T1/de active Pending
- 1991-08-14 CA CA002090433A patent/CA2090433A1/en not_active Abandoned
- 1991-08-14 WO PCT/EP1991/001546 patent/WO1992004336A1/en not_active Ceased
- 1991-08-14 EP EP91914890A patent/EP0545983B1/de not_active Expired - Lifetime
- 1991-08-14 DK DK91914890.8T patent/DK0545983T3/da active
- 1991-08-14 KR KR1019930700568A patent/KR930701419A/ko not_active Ceased
1993
- 1993-09-30 GR GR930300084T patent/GR930300084T1/el unknown

Also Published As

Publication number	Publication date
EP0545983A1 (de)	1993-06-16
AU8412591A (en)	1992-03-30
DK0545983T3 (da)	1994-11-28
ES2041617T3 (es)	1994-12-16
IT9021318A1 (it)	1992-02-29
KR930701419A (ko)	1993-06-11
EP0545983B1 (de)	1994-10-26
DE545983T1 (de)	1993-10-14
WO1992004336A1 (en)	1992-03-19
IT1243801B (it)	1994-06-28
DE69104842T2 (de)	1995-03-23
AU650903B2 (en)	1994-07-07
DE69104842D1 (de)	1994-12-01
JP3119872B2 (ja)	2000-12-25
US5424423A (en)	1995-06-13
JPH06503303A (ja)	1994-04-14
CA2090433A1 (en)	1992-03-01
IT9021318A0 (it)	1990-08-29
GR930300084T1 (en)	1993-09-30
ES2041617T1 (es)	1993-12-01

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