ATE113962T1 - Von polypeptiden induzierte monoklonale antikörper gegen oncoproteine. - Google Patents

Von polypeptiden induzierte monoklonale antikörper gegen oncoproteine.

Info

Publication number
ATE113962T1
ATE113962T1 AT84903305T AT84903305T ATE113962T1 AT E113962 T1 ATE113962 T1 AT E113962T1 AT 84903305 T AT84903305 T AT 84903305T AT 84903305 T AT84903305 T AT 84903305T AT E113962 T1 ATE113962 T1 AT E113962T1
Authority
AT
Austria
Prior art keywords
polypeptide
monoclonal antibodies
antibodies against
induced monoclonal
oncoproteins
Prior art date
Application number
AT84903305T
Other languages
English (en)
Inventor
Henry L Niman
Richard Alan Lerner
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Application granted granted Critical
Publication of ATE113962T1 publication Critical patent/ATE113962T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT84903305T 1983-08-17 1984-08-17 Von polypeptiden induzierte monoklonale antikörper gegen oncoproteine. ATE113962T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52408483A 1983-08-17 1983-08-17

Publications (1)

Publication Number Publication Date
ATE113962T1 true ATE113962T1 (de) 1994-11-15

Family

ID=24087698

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84903305T ATE113962T1 (de) 1983-08-17 1984-08-17 Von polypeptiden induzierte monoklonale antikörper gegen oncoproteine.

Country Status (9)

Country Link
EP (2) EP0592026A1 (de)
JP (2) JPS61500068A (de)
AT (1) ATE113962T1 (de)
AU (2) AU580738B2 (de)
CA (1) CA1219232A (de)
DE (1) DE3486356T2 (de)
IT (1) IT1177968B (de)
WO (1) WO1985000807A1 (de)
ZA (1) ZA846439B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591587A (en) * 1983-08-17 1997-01-07 The Scripps Research Institute Polypeptide-induced monoclonal receptors to protein ligands
US5972629A (en) 1984-08-17 1999-10-26 The Scripps Research Institute Method for characterizing antigenic reactivity of biological sample
US4798787A (en) * 1984-09-19 1989-01-17 Cetus Corporation Peptide antibodies and their use in detecting oncogene products
US5028527A (en) * 1988-02-22 1991-07-02 Applied Bio Technology Monoclonal antibodies against activated ras proteins with amino acid mutations at position 13 of the protein
US4898932A (en) * 1985-01-29 1990-02-06 E. I. Du Pont De Nemours And Company Monoclonal antibodies reactive with activated and oncogenic ras p21 proteins
US5081230A (en) * 1987-07-08 1992-01-14 E. I. Dupont Denemours And Company Monoclonal antibodies reactive with normal and oncogenic forms of the ras p21 protein
CA1296660C (en) * 1985-01-29 1992-03-03 Walter P. Carney Monoclonal antibody against a ras oncogene p21 related dodecapeptide
US5084380A (en) * 1985-01-29 1992-01-28 Applied Biotechnology Monoclonal antibodies reactive with activated and oncogenic ras p21 proteins
US5443956A (en) * 1985-01-29 1995-08-22 Oncogene Science, Inc. Detection, quantitation and classification of RAS proteins in body fluids and tissues
US6200764B1 (en) 1985-01-29 2001-03-13 Bayer Corporation Detection, quantitation and classification of ras proteins in body fluids and tissues
EP0203587A3 (de) * 1985-05-30 1989-08-09 F. Hoffmann-La Roche Ag Ras-Oncogene-Peptide und Antikörper
EP0206065A3 (de) * 1985-06-27 1989-04-19 James R. Feramisco Verfahren zum Nachweis von oncogenischen und proto-oncogenischen Proteinen in extrazelligen biologischen Flüssigkeiten
US6083709A (en) * 1985-08-21 2000-07-04 Osi Pharmaceuticals, Inc. Immunoassay for detection of mutant P53 polypeptide in serum
ATE165363T1 (de) * 1985-08-28 1998-05-15 George Pieczenik Verfahren und mittel zur sortierung und bestimmung biologischer informationen
US5866363A (en) 1985-08-28 1999-02-02 Pieczenik; George Method and means for sorting and identifying biological information
WO1987006940A1 (en) * 1986-05-06 1987-11-19 The Regents Of The University Of California ASSAYS AND ANTIBODIES FOR N-myc PROTEINS
DK354487A (da) * 1986-07-11 1988-01-12 Noboru Yanaihara Oncogen-relaterede peptider
JPS6374492A (ja) * 1986-09-18 1988-04-04 Hiroshi Shiyuku モノクロ−ナル抗体
WO1988007057A1 (en) * 1987-03-13 1988-09-22 Amgen Inc. Purified platelet-derived growth factor and methods for purification thereof
AU1874988A (en) * 1987-07-07 1989-03-09 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Hybridoma cell lines, monoclonal antibodies and their use for immunocytochemical detection or fluorescence-activated sorting of cells expressing the c-myb protein and pharmaceutical compositions
US5094941A (en) * 1987-12-31 1992-03-10 Zymogenetics, Inc. Monoclonal antibodies to PDGF
EP0370012A1 (de) * 1988-03-08 1990-05-30 E.I. Du Pont De Nemours And Company Monoklonale antikörper, empfänglich für aktivierte und onkogenische ras p21-proteine
EP0411018B1 (de) * 1988-04-22 1997-06-04 Oncogene Science, Inc. Nachweis, quantifizierung und klassifizierung von ras-proteinen in körperflüssigkeiten und geweben
ATE160877T1 (de) * 1988-08-12 1997-12-15 Ligand Pharm Inc Polypeptid-induzierte monoklonale rezeptoren gegen proteinliganden
ATE180276T1 (de) * 1990-01-26 1999-06-15 Washington Res Found Immunreaktivität gegenüber exprimierten aktivierten oncogenen zur diagnose und behandlung von bösartigen geschwülsten
GB9103974D0 (en) * 1991-02-26 1991-04-10 Norsk Hydro As Therapeutically useful peptides or peptide fragments

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3050311C2 (de) * 1980-03-18 1987-06-04 Ciba Geigy Ag Verfahren zur herstellung fester Tr{ger f}r Prote ine zu analytischen Zwecken
EP0103893A3 (de) * 1982-09-22 1986-03-19 Daicel Chemical Industries, Ltd. Macrocyclische Diester
CA1252046A (en) * 1982-11-04 1989-04-04 Martin J. Cline Methods for oncogenic detection
ZA84617B (en) * 1983-02-14 1984-09-26 Arup Sen Synthetic polypeptides from viryl oncogenes
US4599306A (en) * 1983-04-15 1986-07-08 Amgen Monoclonal antibodies which specifically bind to human immune interferon
ZA873215B (en) * 1986-05-19 1987-10-28 Viral Technologies Inc. Htlv-iii/lav virus related peptides,antibodies to the peptides,vaccines,passive and active immunization against aids virus and diagnostic test for the serological detection of aids virus
CA1339069C (en) * 1987-11-09 1997-07-29 Henry Lee Niman Polypeptide-induced monoclonal receptors to protein ligand
DE3854550T2 (de) * 1987-11-24 1996-04-25 Abbott Lab HIV-Peptide und Methoden für den Nachweis von HIV.

Also Published As

Publication number Publication date
WO1985000807A1 (en) 1985-02-28
AU3395084A (en) 1985-03-12
EP0592026A1 (de) 1994-04-13
EP0152477B1 (de) 1994-11-09
DE3486356D1 (de) 1994-12-15
IT8448736A1 (it) 1986-02-17
JPH07284398A (ja) 1995-10-31
AU580738B2 (en) 1989-02-02
CA1219232A (en) 1987-03-17
IT8448736A0 (it) 1984-08-17
ZA846439B (en) 1985-03-27
JP2592581B2 (ja) 1997-03-19
EP0152477A4 (de) 1987-04-16
JPS61500068A (ja) 1986-01-16
AU3386089A (en) 1989-08-24
AU633253B2 (en) 1993-01-28
IT1177968B (it) 1987-09-03
DE3486356T2 (de) 1995-06-01
EP0152477A1 (de) 1985-08-28

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time