ATE114156T1 - Herstellung von proteinen in aktiver form. - Google Patents

Herstellung von proteinen in aktiver form.

Info

Publication number
ATE114156T1
ATE114156T1 AT88305404T AT88305404T ATE114156T1 AT E114156 T1 ATE114156 T1 AT E114156T1 AT 88305404 T AT88305404 T AT 88305404T AT 88305404 T AT88305404 T AT 88305404T AT E114156 T1 ATE114156 T1 AT E114156T1
Authority
AT
Austria
Prior art keywords
proteins
production
host cells
active form
source
Prior art date
Application number
AT88305404T
Other languages
English (en)
Inventor
Joseph John Patroni
Malcolm Roy Brandon
Original Assignee
Southern Cross Biotech Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Southern Cross Biotech Pty Ltd filed Critical Southern Cross Biotech Pty Ltd
Application granted granted Critical
Publication of ATE114156T1 publication Critical patent/ATE114156T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT88305404T 1987-06-15 1988-06-14 Herstellung von proteinen in aktiver form. ATE114156T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPI247287 1987-06-15

Publications (1)

Publication Number Publication Date
ATE114156T1 true ATE114156T1 (de) 1994-12-15

Family

ID=3772234

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88305404T ATE114156T1 (de) 1987-06-15 1988-06-14 Herstellung von proteinen in aktiver form.

Country Status (14)

Country Link
US (1) US4992531A (de)
JP (1) JPS6447389A (de)
KR (1) KR0126767B1 (de)
CN (1) CN1032425C (de)
AT (1) ATE114156T1 (de)
AU (1) AU609824B2 (de)
CA (1) CA1305284C (de)
DE (1) DE3852116T2 (de)
DK (1) DK322188A (de)
ES (1) ES2065911T3 (de)
IE (1) IE66334B1 (de)
NO (1) NO882635L (de)
NZ (1) NZ225032A (de)
ZA (1) ZA884212B (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU607988B2 (en) * 1987-04-21 1991-03-21 Southern Cross Biotech Pty Ltd. Production of proteins in active forms
EP0295859B1 (de) * 1987-06-15 1994-11-17 Southern Cross Biotech Pty.Ltd. Herstellung von Proteinen in aktiver Form
US5102989A (en) * 1991-03-15 1992-04-07 Merck & Co., Inc. Method of stabilizing recombinant hepatitis B virus surface proteins from recombinant host cells
US5252216A (en) * 1992-03-24 1993-10-12 Smithkline Beecham Corporation Protein purification
JPH0774232B2 (ja) * 1992-08-31 1995-08-09 農林水産省食品総合研究所長 界面活性剤を用いたタンパク質の新規な精製法
JP3279362B2 (ja) * 1992-10-05 2002-04-30 井上 聰一 糖尿病判定方法及び糖尿病判定装置
JP3319812B2 (ja) * 1993-04-05 2002-09-03 井上 聰一 リウマチ判定方法及びリウマチ判定装置
US20030190307A1 (en) 1996-12-24 2003-10-09 Biogen, Inc. Stable liquid interferon formulations
US7153943B2 (en) * 1997-07-14 2006-12-26 Bolder Biotechnology, Inc. Derivatives of growth hormone and related proteins, and methods of use thereof
ATE498409T1 (de) 1998-08-06 2011-03-15 Mountain View Pharmaceuticals Peg-uricase konjugate und verwendung davon
IL152804A0 (en) * 2000-05-16 2003-06-24 Bolder Biotechnology Inc Methods for refolding proteins containing free cysteine residues
WO2004027378A2 (en) 2002-09-20 2004-04-01 Promega Corporation Luminescence-based methods and probes for measuring cytochrome p450 activity
WO2004042003A2 (en) * 2002-11-01 2004-05-21 Promega Corporation Cell lysis compositions, methods of use, apparatus, and kit
DE10309691B4 (de) 2003-02-28 2018-10-04 Hans-Knöll-Institut für Naturstoff-Forschung e.V. Gewinnung von löslichen Proteinen aus der Biomasse rekombinanter Mikroorganismen
US20040180445A1 (en) * 2003-03-12 2004-09-16 Domanico Michael J. Methods and compositions for purification of nucleic acid from a host cell
MX2007012548A (es) 2005-04-11 2008-03-11 Savient Pharmaceuticals Inc Formas variantes de urato oxidasa y uso de las mismas.
SG161247A1 (en) 2005-04-11 2010-05-27 Savient Pharmaceuticals Inc Variant forms of urate oxidase and use thereof
US20080159976A1 (en) * 2005-04-11 2008-07-03 Jacob Hartman Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
US8148123B2 (en) 2005-04-11 2012-04-03 Savient Pharmaceuticals, Inc. Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
EP1883425A1 (de) * 2005-05-23 2008-02-06 Universite De Geneve Injizierbare superparamagnetische nanoteilchen zur behandlung von hyperthermie und verwendung zur bildung eines hyperthermischen implantats
EP2778234B1 (de) 2005-05-31 2017-09-27 Promega Corporation Luminogene und fluorogene verbindungen und verfahren für den nachweis von molekülen oder leiden
JP5033177B2 (ja) 2006-04-12 2012-09-26 サビエント ファーマセウティカルズ インク． 陽イオン界面活性剤によるタンパク質の精製
WO2008076933A2 (en) * 2006-12-14 2008-06-26 Bolder Biotechnology, Inc. Long acting proteins and peptides and methods of making and using the same
JP5597200B2 (ja) * 2008-08-18 2014-10-01 プロメガ コーポレイション ルミネッセンスを生じる化合物およびチトクロムｐ４５０３ａ酵素を検出するための方法
GB0901434D0 (en) * 2009-01-29 2009-03-11 Univ Strathclyde Ballast water treatment system
US9377454B2 (en) 2009-06-25 2016-06-28 Crealta Pharmaceuticals Llc Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy
CN102905690B (zh) 2010-05-21 2016-03-30 西门子医疗保健诊断公司 两性离子试剂
CN102965317A (zh) * 2012-11-27 2013-03-13 江南大学 一种产牛磺酸菌株的筛选方法及用该菌株发酵法生产牛磺酸
US9790537B2 (en) 2014-01-29 2017-10-17 Promega Corporation Quinone-masked probes as labeling reagents for cell uptake measurements
US10131898B2 (en) * 2014-07-22 2018-11-20 Bio-Rad Laboratories, Inc. Buffers for use with polymerases
CN116637177A (zh) 2016-11-11 2023-08-25 好利恩治疗美国公司 泼尼松和尿酸酶分子的组合疗法及其用途
WO2020160325A1 (en) 2019-01-30 2020-08-06 Horizon Pharma Rheumatology Llc Reducing immunogenicity to pegloticase
WO2020160322A1 (en) 2019-01-30 2020-08-06 Horizon Pharma Rheumatology Llc Tolerization reduces intolerance to pegloticase and prolongs the urate lowering effect (triple)
US12269875B2 (en) 2023-08-03 2025-04-08 Jeff R. Peterson Gout flare prevention methods using IL-1BETA blockers

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476049A (en) * 1983-09-20 1984-10-09 Hoffmann-La Roche Inc. Method for the extraction of immune interferon
US4677196A (en) * 1985-09-06 1987-06-30 International Minerals & Chemical Corp. Purification and activation of proteins from insoluble inclusion bodies
US4681761A (en) * 1985-10-24 1987-07-21 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University Major iron-regulated protein of Neisseria gonorrhoeae and its use as vaccine
AU597924B2 (en) * 1985-12-11 1990-06-14 Natinco Nv Solubilization of protein aggregates
AU612133B2 (en) * 1987-02-20 1991-07-04 Natinco Nv Production of proteins in active forms
AU607988B2 (en) * 1987-04-21 1991-03-21 Southern Cross Biotech Pty Ltd. Production of proteins in active forms

Also Published As

Publication number Publication date
IE881815L (en) 1988-12-15
DK322188A (da) 1988-12-17
AU609824B2 (en) 1991-05-09
US4992531A (en) 1991-02-12
NO882635D0 (no) 1988-06-15
DE3852116D1 (de) 1994-12-22
IE66334B1 (en) 1995-12-27
JPS6447389A (en) 1989-02-21
NO882635L (no) 1988-12-19
DK322188D0 (da) 1988-06-14
ES2065911T3 (es) 1995-03-01
CN1032425C (zh) 1996-07-31
KR900000380A (ko) 1990-01-30
CA1305284C (en) 1992-07-14
CN88103725A (zh) 1988-12-28
DE3852116T2 (de) 1995-03-30
NZ225032A (en) 1991-02-26
ZA884212B (en) 1989-03-29
AU1763288A (en) 1988-12-15
KR0126767B1 (ko) 1997-12-29

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee