ATE114156T1 - Herstellung von proteinen in aktiver form. - Google Patents
Herstellung von proteinen in aktiver form.Info
- Publication number
- ATE114156T1 ATE114156T1 AT88305404T AT88305404T ATE114156T1 AT E114156 T1 ATE114156 T1 AT E114156T1 AT 88305404 T AT88305404 T AT 88305404T AT 88305404 T AT88305404 T AT 88305404T AT E114156 T1 ATE114156 T1 AT E114156T1
- Authority
- AT
- Austria
- Prior art keywords
- proteins
- production
- host cells
- active form
- source
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/06—Lysis of microorganisms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Endocrinology (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Mycology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPI247287 | 1987-06-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE114156T1 true ATE114156T1 (de) | 1994-12-15 |
Family
ID=3772234
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88305404T ATE114156T1 (de) | 1987-06-15 | 1988-06-14 | Herstellung von proteinen in aktiver form. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4992531A (de) |
| JP (1) | JPS6447389A (de) |
| KR (1) | KR0126767B1 (de) |
| CN (1) | CN1032425C (de) |
| AT (1) | ATE114156T1 (de) |
| AU (1) | AU609824B2 (de) |
| CA (1) | CA1305284C (de) |
| DE (1) | DE3852116T2 (de) |
| DK (1) | DK322188A (de) |
| ES (1) | ES2065911T3 (de) |
| IE (1) | IE66334B1 (de) |
| NO (1) | NO882635L (de) |
| NZ (1) | NZ225032A (de) |
| ZA (1) | ZA884212B (de) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU607988B2 (en) * | 1987-04-21 | 1991-03-21 | Southern Cross Biotech Pty Ltd. | Production of proteins in active forms |
| EP0295859B1 (de) * | 1987-06-15 | 1994-11-17 | Southern Cross Biotech Pty.Ltd. | Herstellung von Proteinen in aktiver Form |
| US5102989A (en) * | 1991-03-15 | 1992-04-07 | Merck & Co., Inc. | Method of stabilizing recombinant hepatitis B virus surface proteins from recombinant host cells |
| US5252216A (en) * | 1992-03-24 | 1993-10-12 | Smithkline Beecham Corporation | Protein purification |
| JPH0774232B2 (ja) * | 1992-08-31 | 1995-08-09 | 農林水産省食品総合研究所長 | 界面活性剤を用いたタンパク質の新規な精製法 |
| JP3279362B2 (ja) * | 1992-10-05 | 2002-04-30 | 井上 聰一 | 糖尿病判定方法及び糖尿病判定装置 |
| JP3319812B2 (ja) * | 1993-04-05 | 2002-09-03 | 井上 聰一 | リウマチ判定方法及びリウマチ判定装置 |
| US20030190307A1 (en) | 1996-12-24 | 2003-10-09 | Biogen, Inc. | Stable liquid interferon formulations |
| US7153943B2 (en) * | 1997-07-14 | 2006-12-26 | Bolder Biotechnology, Inc. | Derivatives of growth hormone and related proteins, and methods of use thereof |
| CA2338665C (en) | 1998-08-06 | 2011-01-18 | Mountain View Pharmaceuticals, Inc. | Peg-urate oxidase conjugates and use thereof |
| CN1318443C (zh) * | 2000-05-16 | 2007-05-30 | 博尔德生物技术公司 | 含游离半胱氨酸残基的蛋白重折叠的方法 |
| CA2497560A1 (en) | 2002-09-20 | 2004-04-01 | Promega Corporation | Luminescence-based methods and probes for measuring cytochrome p450 activity |
| EP1558748A4 (de) * | 2002-11-01 | 2008-10-22 | Promega Corp | Zellysezusammensetzungen, verwendungsverfahren, vorrichtung und kit |
| DE10309691B4 (de) | 2003-02-28 | 2018-10-04 | Hans-Knöll-Institut für Naturstoff-Forschung e.V. | Gewinnung von löslichen Proteinen aus der Biomasse rekombinanter Mikroorganismen |
| US20040180445A1 (en) * | 2003-03-12 | 2004-09-16 | Domanico Michael J. | Methods and compositions for purification of nucleic acid from a host cell |
| US8148123B2 (en) | 2005-04-11 | 2012-04-03 | Savient Pharmaceuticals, Inc. | Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase |
| US8188224B2 (en) | 2005-04-11 | 2012-05-29 | Savient Pharmaceuticals, Inc. | Variant forms of urate oxidase and use thereof |
| WO2008051178A2 (en) | 2006-04-12 | 2008-05-02 | Savient Pharmaceuticals, Inc. | Purification of proteins with cationic surfactant |
| US7811800B2 (en) | 2005-04-11 | 2010-10-12 | Savient Pharmaceuticals, Inc. | Variant form of urate oxidase and use thereof |
| US20080159976A1 (en) * | 2005-04-11 | 2008-07-03 | Jacob Hartman | Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase |
| JP2008545665A (ja) * | 2005-05-23 | 2008-12-18 | ユニベルシテ ドゥ ジュネーブ | 高体温による処置のための注入可能な超常磁性ナノ粒子および高体温インプラントを形成するための使用 |
| EP1885875B1 (de) | 2005-05-31 | 2019-05-22 | Promega Corporation | Luminogene und fluorogene verbindungen und verfahren für den nachweis von molekülen oder leiden |
| EP2102355B1 (de) | 2006-12-14 | 2016-03-02 | Bolder Biotechnology, Inc. | Proteine und peptide mit langer wirkung sowie verfahren zu ihrer herstellung und verwendung |
| JP5597200B2 (ja) * | 2008-08-18 | 2014-10-01 | プロメガ コーポレイション | ルミネッセンスを生じる化合物およびチトクロムp4503a酵素を検出するための方法 |
| GB0901434D0 (en) | 2009-01-29 | 2009-03-11 | Univ Strathclyde | Ballast water treatment system |
| EP4635567A3 (de) | 2009-06-25 | 2025-12-03 | Horizon Therapeutics USA, Inc. | Verfahren und kits zur prävention des infusionsreaktionsrisikos und antikörpervermittelter reaktionsverlust durch überwachung von serumharnsäure während der pegylierten harnasetherapie |
| WO2011146595A2 (en) * | 2010-05-21 | 2011-11-24 | Siemens Healthcare Diagnostics Inc. | Zwitterionic reagents |
| CN102965317A (zh) * | 2012-11-27 | 2013-03-13 | 江南大学 | 一种产牛磺酸菌株的筛选方法及用该菌株发酵法生产牛磺酸 |
| EP3099683B1 (de) | 2014-01-29 | 2020-08-05 | Promega Corporation | Chinonmaskierte sonden als markierungsreagenzien für zellaufnahmemessungen |
| EP3172332B1 (de) * | 2014-07-22 | 2020-10-14 | Bio-rad Laboratories, Inc. | Puffer zur verwendung mit polymerasen |
| CN110234340A (zh) | 2016-11-11 | 2019-09-13 | 好利恩风湿病制药有限责任公司 | 泼尼松和尿酸酶分子的组合疗法及其用途 |
| US20200237881A1 (en) | 2019-01-30 | 2020-07-30 | Horizon Pharma Rheumatology Llc | Reducing immunogenicity to pegloticase |
| US12121566B2 (en) | 2019-01-30 | 2024-10-22 | Horizon Therapeutics Usa, Inc. | Methods for treating gout |
| US12269875B2 (en) | 2023-08-03 | 2025-04-08 | Jeff R. Peterson | Gout flare prevention methods using IL-1BETA blockers |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4476049A (en) * | 1983-09-20 | 1984-10-09 | Hoffmann-La Roche Inc. | Method for the extraction of immune interferon |
| US4677196A (en) * | 1985-09-06 | 1987-06-30 | International Minerals & Chemical Corp. | Purification and activation of proteins from insoluble inclusion bodies |
| US4681761A (en) * | 1985-10-24 | 1987-07-21 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University | Major iron-regulated protein of Neisseria gonorrhoeae and its use as vaccine |
| AU597924B2 (en) * | 1985-12-11 | 1990-06-14 | Natinco Nv | Solubilization of protein aggregates |
| AU612133B2 (en) * | 1987-02-20 | 1991-07-04 | Natinco Nv | Production of proteins in active forms |
| AU607988B2 (en) * | 1987-04-21 | 1991-03-21 | Southern Cross Biotech Pty Ltd. | Production of proteins in active forms |
-
1987
- 1987-06-15 AU AU17632/88A patent/AU609824B2/en not_active Ceased
-
1988
- 1988-06-13 ZA ZA884212A patent/ZA884212B/xx unknown
- 1988-06-13 US US07/206,006 patent/US4992531A/en not_active Expired - Fee Related
- 1988-06-14 DK DK322188A patent/DK322188A/da not_active Application Discontinuation
- 1988-06-14 CA CA000569448A patent/CA1305284C/en not_active Expired - Fee Related
- 1988-06-14 ES ES88305404T patent/ES2065911T3/es not_active Expired - Lifetime
- 1988-06-14 DE DE3852116T patent/DE3852116T2/de not_active Expired - Fee Related
- 1988-06-14 AT AT88305404T patent/ATE114156T1/de not_active IP Right Cessation
- 1988-06-15 NO NO882635A patent/NO882635L/no unknown
- 1988-06-15 NZ NZ225032A patent/NZ225032A/xx unknown
- 1988-06-15 CN CN88103725A patent/CN1032425C/zh not_active Expired - Fee Related
- 1988-06-15 JP JP63147909A patent/JPS6447389A/ja active Pending
- 1988-06-15 IE IE181588A patent/IE66334B1/en not_active IP Right Cessation
- 1988-06-16 KR KR1019880007253A patent/KR0126767B1/ko not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IE66334B1 (en) | 1995-12-27 |
| ZA884212B (en) | 1989-03-29 |
| CN88103725A (zh) | 1988-12-28 |
| CA1305284C (en) | 1992-07-14 |
| AU1763288A (en) | 1988-12-15 |
| NO882635L (no) | 1988-12-19 |
| DE3852116D1 (de) | 1994-12-22 |
| NZ225032A (en) | 1991-02-26 |
| ES2065911T3 (es) | 1995-03-01 |
| NO882635D0 (no) | 1988-06-15 |
| JPS6447389A (en) | 1989-02-21 |
| IE881815L (en) | 1988-12-15 |
| AU609824B2 (en) | 1991-05-09 |
| CN1032425C (zh) | 1996-07-31 |
| DK322188D0 (da) | 1988-06-14 |
| DE3852116T2 (de) | 1995-03-30 |
| US4992531A (en) | 1991-02-12 |
| KR900000380A (ko) | 1990-01-30 |
| DK322188A (da) | 1988-12-17 |
| KR0126767B1 (ko) | 1997-12-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |