ATE114968T1 - Verfahren zur herstellung von bromocriptin enthaltenden arzneimittelzubereitungen mit hoher stabilität und in beziehung zueinander stehende produkte. - Google Patents

Verfahren zur herstellung von bromocriptin enthaltenden arzneimittelzubereitungen mit hoher stabilität und in beziehung zueinander stehende produkte.

Info

Publication number: ATE114968T1
Authority: AT; Austria
Prior art keywords: products; bromocriptin; manufacture; high stability; containing medicinal
Prior art date: 1989-04-07

Application number

AT90106403T

Other languages

English (en)

Inventor

Luigi Moro

Achille Fiori

Alberto Natali

Original Assignee

Poli Ind Chimica Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-04-07

Filing date

1990-04-04

Publication date

1994-12-15

1990-04-04 Application filed by Poli Ind Chimica Spa filed Critical Poli Ind Chimica Spa

1994-12-15 Application granted granted Critical

1994-12-15 Publication of ATE114968T1 publication Critical patent/ATE114968T1/de

Links

238000000034 method Methods 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
229940126601 medicinal product Drugs 0.000 title 1
239000000546 pharmaceutical excipient Substances 0.000 abstract 3
239000004480 active ingredient Substances 0.000 abstract 2
OZVBMTJYIDMWIL-AYFBDAFISA-N bromocriptine Chemical compound C1=CC(C=2[C@H](N(C)C[C@@H](C=2)C(=O)N[C@]2(C(=O)N3[C@H](C(N4CCC[C@H]4[C@]3(O)O2)=O)CC(C)C)C(C)C)C2)=C3C2=C(Br)NC3=C1 OZVBMTJYIDMWIL-AYFBDAFISA-N 0.000 abstract 1
229960002802 bromocriptine Drugs 0.000 abstract 1
239000002775 capsule Substances 0.000 abstract 1
239000008187 granular material Substances 0.000 abstract 1
238000005469 granulation Methods 0.000 abstract 1
230000003179 granulation Effects 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

Landscapes

Health & Medical Sciences (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT90106403T 1989-04-07 1990-04-04 Verfahren zur herstellung von bromocriptin enthaltenden arzneimittelzubereitungen mit hoher stabilität und in beziehung zueinander stehende produkte. ATE114968T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT8920063A IT1235053B (it)	1989-04-07	1989-04-07	Metodi per la preparazione di composizioni farmaceutiche a base di bromocriptina dotate di elevata stabilita' e prodotti derivanti.

Publications (1)

Publication Number	Publication Date
ATE114968T1 true ATE114968T1 (de)	1994-12-15

Family

ID=11163518

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90106403T ATE114968T1 (de)	1989-04-07	1990-04-04	Verfahren zur herstellung von bromocriptin enthaltenden arzneimittelzubereitungen mit hoher stabilität und in beziehung zueinander stehende produkte.

Country Status (9)

Country	Link
US (1)	US5066495A (de)
EP (1)	EP0391374B1 (de)
AT (1)	ATE114968T1 (de)
DD (1)	DD293961B5 (de)
DE (2)	DE391374T1 (de)
DK (1)	DK0391374T3 (de)
ES (1)	ES2029776T3 (de)
GR (1)	GR900300172T1 (de)
IT (1)	IT1235053B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2030174C (en) *	1990-01-10	1996-12-24	Anthony H. Cincotta	Process for the long term reduction of body fat stores, insulin resistance, hyperinsulinemia and hypoglycemia in vertebrates
US5292520A (en) *	1990-09-13	1994-03-08	Akzo N.V.	Stabilized solid pharmaceutical composition containing acid addition salts of a basic drug and an alkaline stabilizer
US5225204A (en) *	1991-11-05	1993-07-06	Chen Jivn Ren	Stable dosage of levothyroxine sodium and process of production
IL112106A0 (en) *	1993-12-22	1995-03-15	Ergo Science Inc	Accelerated release composition containing bromocriptine
SI9700186B (sl) *	1997-07-14	2006-10-31	Lek, Tovarna Farmacevtskih In Kemicnih Izdelkov, D.D.	Nova farmacevtska oblika z nadzorovanim sproscanjem zdravilnih ucinkovin
US6129931A (en) *	1998-09-03	2000-10-10	Isp Investments Inc.	Controlled-release, drug-delivery tableted composition including a complex between poly(maleic diacid-alkyl vinyl ether) and polyvinylpyrrolidone
US8226972B2 (en) *	2001-12-20	2012-07-24	Femmepharma Holding Company, Inc.	Vaginal delivery of drugs
US8821915B2 (en)	2002-08-09	2014-09-02	Veroscience, Llc	Therapeutic process for the treatment of the metabolic syndrome and associated metabolic disorders
AU2007216882B2 (en) *	2003-01-02	2010-03-11	Femmepharma Holding Company, Inc.	Pharmaceutical preparations for treatment of diseases and disorders of the breast
MXPA05007266A (es) *	2003-01-02	2006-01-17	Femmepharma Holding Co Inc	Preparaciones farmaceuticas para tratamientos de enfermedades y trastornos del seno.
US9173836B2 (en)	2003-01-02	2015-11-03	FemmeParma Holding Company, Inc.	Pharmaceutical preparations for treatments of diseases and disorders of the breast
US20080153789A1 (en) *	2006-12-26	2008-06-26	Femmepharma Holding Company, Inc.	Topical administration of danazol
GB0715628D0 (en) *	2007-08-10	2007-09-19	Generics Uk Ltd	Solid valsartan composition
US9352025B2 (en)	2009-06-05	2016-05-31	Veroscience Llc	Combination of dopamine agonists plus first phase insulin secretagogues for the treatment of metabolic disorders
US20110003000A1 (en) *	2009-07-06	2011-01-06	Femmepharma Holding Company, Inc.	Transvaginal Delivery of Drugs
US8431155B1 (en)	2012-04-30	2013-04-30	Veroscience Llc	Bromocriptine formulations
CN105640901A (zh) *	2014-11-10	2016-06-08	匈牙利吉瑞大药厂	一种利用新型生产工艺制备甲磺酸溴隐亭片的方法及其应用
CN120713906A (zh)	2016-04-20	2025-09-30	维罗技术有限责任公司	用于治疗代谢失调的组合物和方法
PL3697418T3 (pl)	2017-10-18	2025-02-03	Veroscience Llc	Polepszone preparaty bromokryptyny
CA3149877A1 (en)	2019-09-23	2021-04-01	Anthony H. Cincotta	Method for inducing tumor regression
CN117323305B (zh) *	2023-11-07	2024-06-07	杭州沐源生物医药科技有限公司	溴隐亭片剂及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL113512C (de) *	1962-01-25
US3836618A (en) *	1971-12-23	1974-09-17	American Home Prod	Process for the uniform distribution of a drug on a granulated base
NL7314066A (de) *	1972-10-18	1974-04-22
DE3045135A1 (de) *	1980-11-29	1982-06-09	Sandoz-Patent-GmbH, 7850 Lörrach	Pharmazeutische kompositionen enthaltende bioabbaubare polymere
US4479911A (en) *	1982-01-28	1984-10-30	Sandoz, Inc.	Process for preparation of microspheres and modification of release rate of core material
IE55579B1 (en) *	1982-07-06	1990-11-07	Sterwin Ag	Processes for preparing tablets by a modified'wet-granulation'technique
US4742054A (en) *	1982-11-23	1988-05-03	Naftchi Nosrat E	Treatment of mammals suffering from damage to the central nervous system
GB2154874B (en) *	1984-02-29	1987-11-04	Sandoz Ltd	Bromoscriptine compositions

1989
- 1989-04-07 IT IT8920063A patent/IT1235053B/it active
1990
- 1990-03-30 US US07/502,520 patent/US5066495A/en not_active Expired - Lifetime
- 1990-04-04 ES ES90106403T patent/ES2029776T3/es not_active Expired - Lifetime
- 1990-04-04 DK DK90106403.0T patent/DK0391374T3/da active
- 1990-04-04 DE DE199090106403T patent/DE391374T1/de active Pending
- 1990-04-04 EP EP90106403A patent/EP0391374B1/de not_active Expired - Lifetime
- 1990-04-04 AT AT90106403T patent/ATE114968T1/de not_active IP Right Cessation
- 1990-04-04 DE DE69014691T patent/DE69014691T2/de not_active Expired - Lifetime
- 1990-04-05 DD DD33947390A patent/DD293961B5/de not_active IP Right Cessation
1991
- 1991-09-27 GR GR90300172T patent/GR900300172T1/el unknown

Also Published As

Publication number	Publication date
EP0391374A3 (de)	1992-07-01
DK0391374T3 (da)	1995-04-24
IT1235053B (it)	1992-06-17
DE69014691D1 (de)	1995-01-19
EP0391374B1 (de)	1994-12-07
EP0391374A2 (de)	1990-10-10
ES2029776T3 (es)	1995-02-01
DE391374T1 (de)	1991-02-28
GR900300172T1 (en)	1991-09-27
US5066495A (en)	1991-11-19
DE69014691T2 (de)	1995-04-20
IT8920063A0 (it)	1989-04-07
DD293961B5 (de)	1994-11-10
ES2029776T1 (es)	1992-10-01

Similar Documents

Publication	Publication Date	Title
DE69014691D1 (de)	1995-01-19	Verfahren zur Herstellung von Bromocriptin enthaltenden Arzneimittelzubereitungen mit hoher Stabilität und in Beziehung zueinander stehende Produkte.
ES8603753A1 (es)	1986-01-01	Procedimiento de fabricacion de comprimidos efervescentes
ATE210968T1 (de)	2002-01-15	Verfahren zur herstellung von schnelllöslicher tabletten und schnelllöslichen tablette beinhaltend xylitol
ATE74513T1 (de)	1992-04-15	Stabilisierte arzneistoffe, verfahren zu ihrer herstellung sowie stabile arzneizubereitungen.
HU903846D0 (en)	1990-11-28	Process for producing imidazolyl-alkenic acids and pharmaceutical preparatives containing these compounds as active substance
FI905956A0 (fi)	1990-12-03	Foerfarande foer producering av ett biologiskt aktivt protein.
PT88557A (pt)	1988-10-01	Process for the production of pharmaceutical compositions for sustained and controlled release of drug comprising water-insoluble polypeptides
HUT49629A (en)	1989-10-30	Process for producing peptide-boronic acid derivatives inhibiting trypsin-like proteases and pharmaceutical compositions comprising such compounds as active ingredient
ES2041699T3 (es)	1993-12-01	Procedimiento de preparacion de un medicamento a base de fenofibrato y medicamento obtenido por este procedimiento.
NO894689L (no)	1990-05-28	Fremgangsmaate for fremstilling av blekende granulat.
HUT51254A (en)	1990-04-28	Process for producing amino acid derivatives and pharmaceutical compositions comprising same as active ingredient
ATE2191T1 (de)	1983-01-15	Rosmarinsaeure-phospholipid komplexe, verfahren zur ihrer herstellung und sie enthaltende arzneimittel.
ATE330943T1 (de)	2006-07-15	Herstellungsverfahren von huperzine a und deren analogen und verbindungen nützlich dazu
DK0621038T3 (da)	1999-08-16	Farmaceutiske præparater indeholdende silikatpolymere
DE3767998D1 (de)	1991-03-14	Clodronat-haltige arzneimittel und verfahren zur herstellung derselben.
HUT54657A (en)	1991-03-28	Process for producing amino acid antagonists with vitalizing effect and pharmaceutical compositions comprising such compounds
HUT52500A (en)	1990-07-28	Process for producing antibacterial 1-terc-alkyl-substituted naphtiridine- and quinoline-carboxylic acids and pharmaceutical compositions containing them as active components
SE8800080L (sv)	1989-07-14	Laekemedelskomposition
IL78017A0 (en)	1986-07-31	Sustained release tablets of theophylline
DK330787A (da)	1987-12-27	Stabiliseret farmaceutisk sammensaetning
FI871378A0 (fi)	1987-03-30	Menetelmä valmistaa farmaseuttiseen käyttöön tarkoitettu muotokappale pelleteistä
ATE136465T1 (de)	1996-04-15	Verwendung von gibberellinen zur herstellung eines arzneimittels zur behandlung von prostatitis
DE3875144D1 (de)	1992-11-12	Verfahren zur herstellung magensaftstabiler und darmloeslicher kuegelchen von verdauungsenzymen und die auf diese weise erhaltenen arzneimittel.
IL82523A0 (en)	1987-11-30	Microbicidal compositions,their manufacture and drugs containing them
MX10146A (es)	1993-09-01	Procedimiento para la produccion de preparados medicinales que contienen y liberan sustancias activas y producto obtenido.

Legal Events

Date	Code	Title
1995-05-15	UEP	Publication of translation of european patent specification
2000-11-15	EEIH	Change in the person of patent owner
2009-01-15	REN	Ceased due to non-payment of the annual fee