ATE115558T1 - Harnstoffderivate, deren herstellung sowie diese enthaltende pharmazeutische zusammensetzungen. - Google Patents

Harnstoffderivate, deren herstellung sowie diese enthaltende pharmazeutische zusammensetzungen.

Info

Publication number
ATE115558T1
ATE115558T1 AT91301868T AT91301868T ATE115558T1 AT E115558 T1 ATE115558 T1 AT E115558T1 AT 91301868 T AT91301868 T AT 91301868T AT 91301868 T AT91301868 T AT 91301868T AT E115558 T1 ATE115558 T1 AT E115558T1
Authority
AT
Austria
Prior art keywords
urea derivatives
pharmaceutical compositions
production
compositions including
salts
Prior art date
Application number
AT91301868T
Other languages
English (en)
Inventor
Noriki Ito
Koyo Matsuda
Kiyoshi Iwaoka
Yuichi Iizumi
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Application granted granted Critical
Publication of ATE115558T1 publication Critical patent/ATE115558T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/26—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT91301868T 1990-03-12 1991-03-06 Harnstoffderivate, deren herstellung sowie diese enthaltende pharmazeutische zusammensetzungen. ATE115558T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6075490 1990-03-12

Publications (1)

Publication Number Publication Date
ATE115558T1 true ATE115558T1 (de) 1994-12-15

Family

ID=13151377

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91301868T ATE115558T1 (de) 1990-03-12 1991-03-06 Harnstoffderivate, deren herstellung sowie diese enthaltende pharmazeutische zusammensetzungen.

Country Status (14)

Country Link
EP (1) EP0447116B1 (de)
JP (1) JPH04234839A (de)
KR (1) KR910016689A (de)
CN (1) CN1024790C (de)
AT (1) ATE115558T1 (de)
AU (1) AU643759B2 (de)
CA (1) CA2037669A1 (de)
DE (1) DE69105786T2 (de)
DK (1) DK0447116T3 (de)
ES (1) ES2068497T3 (de)
FI (1) FI911189L (de)
GR (1) GR3015149T3 (de)
HU (1) HUT57712A (de)
IE (1) IE910780A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU632809B2 (en) * 1989-05-25 1993-01-14 Takeda Chemical Industries Ltd. Benzocycloalkane benzopyran and benzothiopyran urea derivatives and production thereof
RU94046149A (ru) * 1992-05-28 1996-11-27 Пфайзер Инк. (US) Новые n-арил и n-гетероарил производные мочевины как ингибиторы ацил кофермента а:холестерин ацил трансферазы (асат) фармацевтическая композиция, способ ингибирования (асат)
US5401758A (en) * 1993-10-07 1995-03-28 Bristol-Myers Squibb Company Pyridinyl cyanoguanidine compounds
DE4401893A1 (de) * 1994-01-24 1995-07-27 Bayer Ag Substituierte Arylharnstoffe
EP0742208A1 (de) * 1995-05-05 1996-11-13 Grelan Pharmaceutical Co., Ltd. 2-Ureido-benzamid-Derivate
KR100388345B1 (ko) 1995-10-05 2004-03-30 교토 야쿠힝 고교 가부시키가이샤 신규헤테로시클릭유도체및이것의의약용도
US5866609A (en) * 1996-08-09 1999-02-02 Ss Pharmaceutical Co., Ltd. Substituted vinylurea derivatives and medicine containing the same
EP1425016B1 (de) * 2001-09-05 2010-06-02 Minerva Biotechnologies Corporation Zusammensetzungen und deren verwendung zur behandlung von krebs
FR2831166B1 (fr) * 2001-10-18 2004-02-27 Sanofi Synthelabo Aralkyl-tetrahydro-pyridines, leur preparation et compositions pharmaceutiques les contenant
AU2003252638B8 (en) 2002-07-17 2009-03-05 Kyoto Pharmaceutical Industries, Ltd. Novel indoline compound and medicinal use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2928485A1 (de) * 1979-07-14 1981-01-29 Bayer Ag Verwendung von harnstoffderivaten als arzneimittel bei der behandlung von fettstoffwechselstoerungen
US4473579A (en) * 1982-01-26 1984-09-25 American Cyanamid Company Antiatherosclerotic tetrasubstituted ureas and thioureas
JPS58222063A (ja) * 1982-06-17 1983-12-23 Nippon Tokushu Noyaku Seizo Kk ベンジルウレア誘導体、その製法及び農園芸用殺菌剤
US4868210A (en) * 1988-03-30 1989-09-19 Warner-Lambert Company Antihyperlipidemic and antiatherosclerotic compounds and compositions
AU632809B2 (en) * 1989-05-25 1993-01-14 Takeda Chemical Industries Ltd. Benzocycloalkane benzopyran and benzothiopyran urea derivatives and production thereof

Also Published As

Publication number Publication date
DE69105786D1 (de) 1995-01-26
FI911189A7 (fi) 1991-09-13
EP0447116A1 (de) 1991-09-18
EP0447116B1 (de) 1994-12-14
AU643759B2 (en) 1993-11-25
HUT57712A (en) 1991-12-30
DK0447116T3 (da) 1995-05-15
CN1054766A (zh) 1991-09-25
CA2037669A1 (en) 1991-09-13
FI911189L (fi) 1991-09-13
JPH04234839A (ja) 1992-08-24
IE910780A1 (en) 1991-09-25
ES2068497T3 (es) 1995-04-16
AU7276291A (en) 1991-09-12
DE69105786T2 (de) 1995-04-27
CN1024790C (zh) 1994-06-01
HU910784D0 (en) 1991-09-30
KR910016689A (ko) 1991-11-05
FI911189A0 (fi) 1991-03-11
GR3015149T3 (en) 1995-05-31

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee