ATE11670T1 - 7-fluor-dibenzo(b,f)thiepin-derivate, verfahren zu ihrer herstellung und aufloesung und diese enthaltende zusammenstellungen. - Google Patents

7-fluor-dibenzo(b,f)thiepin-derivate, verfahren zu ihrer herstellung und aufloesung und diese enthaltende zusammenstellungen.

Info

Publication number
ATE11670T1
ATE11670T1 AT81301640T AT81301640T ATE11670T1 AT E11670 T1 ATE11670 T1 AT E11670T1 AT 81301640 T AT81301640 T AT 81301640T AT 81301640 T AT81301640 T AT 81301640T AT E11670 T1 ATE11670 T1 AT E11670T1
Authority
AT
Austria
Prior art keywords
dibenzo
fluoro
hydroxy
thiepin
amino
Prior art date
Application number
AT81301640T
Other languages
English (en)
Inventor
Joshua Rokach
Clarence S. Rooney
Edward J. Cragoe
Original Assignee
Merck & Co. Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co. Inc. filed Critical Merck & Co. Inc.
Application granted granted Critical
Publication of ATE11670T1 publication Critical patent/ATE11670T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/14—[b,f]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Insulating Materials (AREA)
  • Paints Or Removers (AREA)
AT81301640T 1980-11-24 1981-04-14 7-fluor-dibenzo(b,f)thiepin-derivate, verfahren zu ihrer herstellung und aufloesung und diese enthaltende zusammenstellungen. ATE11670T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20943480A 1980-11-24 1980-11-24
EP81301640A EP0052912B1 (de) 1980-11-24 1981-04-14 7-Fluor-dibenzo(b,f)thiepin-Derivate, Verfahren zu ihrer Herstellung und Auflösung und diese enthaltende Zusammenstellungen

Publications (1)

Publication Number Publication Date
ATE11670T1 true ATE11670T1 (de) 1985-02-15

Family

ID=22778742

Family Applications (1)

Application Number Title Priority Date Filing Date
AT81301640T ATE11670T1 (de) 1980-11-24 1981-04-14 7-fluor-dibenzo(b,f)thiepin-derivate, verfahren zu ihrer herstellung und aufloesung und diese enthaltende zusammenstellungen.

Country Status (14)

Country Link
EP (1) EP0052912B1 (de)
JP (1) JPS5788176A (de)
AT (1) ATE11670T1 (de)
CA (1) CA1175846A (de)
DE (1) DE3168733D1 (de)
DK (1) DK168881A (de)
ES (1) ES501935A0 (de)
FI (1) FI811305L (de)
GR (1) GR75218B (de)
IE (1) IE51136B1 (de)
NO (1) NO811187L (de)
NZ (1) NZ196805A (de)
PT (1) PT73000B (de)
ZA (1) ZA812665B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535171A (en) * 1982-11-18 1985-08-13 Merck Frosst Canada, Inc. Dibenzo[b,f]thiepin-3-carboxaldehydes as prostaglandin antagonists
US4622403A (en) * 1983-10-11 1986-11-11 Merck Frosst Canada, Inc. 6-H dibenz[b,f]thiepin compounds
CA1240699A (en) * 1984-05-14 1988-08-16 Thomas R. Verhoeven Preparation of dibenzo(b,f)thiepin compounds
US4558037A (en) * 1984-06-04 1985-12-10 Merck & Co., Inc. Cardiovascular composition
KR100769084B1 (ko) 2005-02-17 2007-10-22 동우신테크 주식회사 디벤조티에핀 유도체의 제조 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51108082A (en) * 1975-03-15 1976-09-25 Nippon Chemiphar Co 99 karubokishi 10*111 jihidorojibenzo * b*f * chepinjudotainoseiho
US4101667A (en) * 1975-05-30 1978-07-18 Nippon Chemiphar Co., Ltd. Benzo[b,f]thiepin derivatives
GB1487280A (en) * 1975-11-06 1977-09-28 Nippon Chemiphar Co 10,11-dihydrodibenzo-(b,f)-thiepin-1-carboxylic acid derivatives and a process for producing the same
JPS5346989A (en) * 1976-10-06 1978-04-27 Nippon Chemiphar Co Ltd Novel dibenzo(b,f)thiepin derivatives and their preparation
JPS5346990A (en) * 1976-10-06 1978-04-27 Nippon Chemiphar Co Ltd Dibenzo(d,f)thiepin derivatives and their preparation
PT68303A (en) * 1977-07-26 1978-08-01 Merck & Co Inc Process for the preparation of dibenzo/b,f/thiepin
FI801638A7 (fi) * 1979-06-01 1981-01-01 Merck & Co Inc Prostaglandiiniantagonisteja.

Also Published As

Publication number Publication date
ES8306140A1 (es) 1982-08-16
EP0052912B1 (de) 1985-02-06
ES501935A0 (es) 1982-08-16
FI811305A7 (fi) 1982-05-25
IE810798L (en) 1982-05-24
GR75218B (de) 1984-07-13
PT73000A (en) 1981-06-01
PT73000B (en) 1983-02-08
ZA812665B (en) 1982-04-28
DK168881A (da) 1982-05-25
NZ196805A (en) 1983-07-15
JPS5788176A (en) 1982-06-01
NO811187L (no) 1982-05-25
CA1175846A (en) 1984-10-09
DE3168733D1 (en) 1985-03-21
FI811305L (fi) 1982-05-25
EP0052912A1 (de) 1982-06-02
IE51136B1 (en) 1986-10-15

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee