ATE117320T1 - Amide der ge 2270-antibiotika. - Google Patents

Amide der ge 2270-antibiotika.

Info

Publication number
ATE117320T1
ATE117320T1 AT92901892T AT92901892T ATE117320T1 AT E117320 T1 ATE117320 T1 AT E117320T1 AT 92901892 T AT92901892 T AT 92901892T AT 92901892 T AT92901892 T AT 92901892T AT E117320 T1 ATE117320 T1 AT E117320T1
Authority
AT
Austria
Prior art keywords
antibiotics
amides
amide derivatives
antibiotic
preparing
Prior art date
Application number
AT92901892T
Other languages
English (en)
Inventor
Paolo Tavecchia
Sergio Lociuro
Romeo Ciabatti
Enrico Selva
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Application granted granted Critical
Publication of ATE117320T1 publication Critical patent/ATE117320T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Saccharide Compounds (AREA)
AT92901892T 1991-01-03 1992-01-02 Amide der ge 2270-antibiotika. ATE117320T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91100123 1991-01-03

Publications (1)

Publication Number Publication Date
ATE117320T1 true ATE117320T1 (de) 1995-02-15

Family

ID=8206281

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92901892T ATE117320T1 (de) 1991-01-03 1992-01-02 Amide der ge 2270-antibiotika.

Country Status (18)

Country Link
US (1) US5599791A (de)
EP (2) EP0494078A1 (de)
JP (1) JP3183508B2 (de)
KR (1) KR100225763B1 (de)
CN (1) CN1063110A (de)
AT (1) ATE117320T1 (de)
AU (1) AU662122B2 (de)
CA (1) CA2093219C (de)
DE (1) DE69201236T2 (de)
ES (1) ES2067325T3 (de)
FI (1) FI932944A0 (de)
HU (1) HU224072B1 (de)
IE (1) IE920005A1 (de)
IL (1) IL100572A (de)
MX (1) MX9200015A (de)
NZ (1) NZ241216A (de)
WO (1) WO1992012172A1 (de)
ZA (1) ZA927B (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2071143T3 (es) * 1990-03-08 1995-06-16 Lepetit Spa Factores b1, b2, c1, c2, d1, d2, e y t del antibiotico ge 2270.
DK0529410T3 (da) * 1991-08-30 1998-05-11 Biosearch Italia Spa Antibiotikum GE 2270 faktor C2a
US5882900A (en) * 1992-09-10 1999-03-16 Gruppo Lepetit S.P.A. Process for the selective increase of production of antibiotic GE 2270 factor a by adding vitamin B12 to nutrient medium
KR960703410A (ko) * 1992-12-22 1996-08-17 프란세스코 마체타 항생물질 GE 37468 A, B 및 C(Antibiotics GE 37468 A, B and C)
DE69600244T2 (de) * 1995-02-07 1998-10-01 Biosearch Italia Spa Basische prolinamid derivate von ge2270 und ge2270-ahnlichten antibiotika
WO1996024608A1 (en) 1995-02-07 1996-08-15 Biosearch Italia S.P.A. Basic oxazoline-amide derivatives of ge 2270 and ge 2270-like antibiotics
ES2186866T3 (es) * 1996-02-14 2003-05-16 Biosearch Italia Spa Derivados de factores del antibiotico ge2270.
JPH1059997A (ja) * 1996-08-22 1998-03-03 Microbial Chem Res Found アミチアマイシンアミド誘導体
US20050166498A1 (en) * 1999-12-17 2005-08-04 Oakey David D. Carpet tile with cutout section, method and apparatus for production and method of installation
GB0024200D0 (en) * 2000-10-03 2000-11-15 Smithkline Beecham Sa Component vaccine
KR20050026401A (ko) * 2002-06-17 2005-03-15 비큐론 파마세티컬스 인코포레이티드 여드름 치료를 위한 ｇｅ 2270 인자 ａ3의 아미드유도체의 용도
JP4805139B2 (ja) 2003-04-30 2011-11-02 モルホケム アクツィエンゲゼルシャフト フューア コンビナートリッシュ ヒェミー 炭疽および他の感染を治療するためのオキサゾリジノン‐キノリンハイブリッド抗生物質の使用
BRPI0417193B8 (pt) 2003-12-18 2021-05-25 Morphochem Ag Fuer Komb Chemie antibióticos híbridos de oxazolidinona-quinolona, seus sais monossódicos, dissódicos ou trissódicos e seus pró-fármacos, composições farmacêuticas, e seu uso
EP2194139A1 (de) * 2004-01-19 2010-06-09 DSM IP Assets B.V. Biochemische Synthese von 6-Amino-Capronsäure
AR060977A1 (es) * 2006-05-31 2008-07-23 Novartis Ag Aminotiazoles y sus usos
BRPI0720542A2 (pt) * 2006-12-20 2014-01-21 Novartis Ag Compostos antibacterianos e processos para a sua produção
US8673601B2 (en) 2007-01-22 2014-03-18 Genomatica, Inc. Methods and organisms for growth-coupled production of 3-hydroxypropionic acid
CN101772506B (zh) * 2007-06-04 2014-02-12 诺华股份有限公司 大环化合物及其用途
US8026386B2 (en) 2007-08-10 2011-09-27 Genomatica, Inc. Methods for the synthesis of olefins and derivatives
EP2229386B1 (de) * 2007-12-12 2015-06-03 Novartis AG Ein aminothiazol derivat und seine verwendung als antibakterieller wirkstoff
CA2712779C (en) 2008-01-22 2021-03-16 Genomatica, Inc. Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol
DK2262901T3 (en) 2008-03-05 2019-01-21 Genomatica Inc ORGANISMS PRODUCING PRIMARY ALCOHOL
ES2656790T3 (es) 2008-03-27 2018-02-28 Genomatica, Inc. Microorganismos para la producción de ácido adípico y otros compuestos
WO2009135074A2 (en) 2008-05-01 2009-11-05 Genomatica, Inc. Microorganisms for the production of methacrylic acid
BRPI0913901A2 (pt) 2008-06-17 2016-12-13 Genomatica Inc micro-organismos e métodos para a biossíntese de fumarato, malato e acrilato
EP2373781A4 (de) 2008-12-16 2012-10-10 Genomatica Inc Mikroorganismen und verfahren zur umwandlung von syngas und anderen kohlenstoffressourcen in nützliche produkte
MY176050A (en) 2009-04-30 2020-07-22 Genomatica Inc Organisms for the production of 1,3-butanediol
BRPI1013505A2 (pt) 2009-04-30 2018-02-14 Genomatica Inc organismos para a produção de isopropanol, n-butanol, e isobutanol
EP2427544B1 (de) 2009-05-07 2019-07-17 Genomatica, Inc. Mikrooganismen und verfahren für die biosynthese von adipat, hexamethylendiamin und 6-aminocapronsäure
JP2012526561A (ja) 2009-05-15 2012-11-01 ゲノマチカ， インク． シクロヘキサノンの産生のための生物
EP2440669A4 (de) 2009-06-10 2013-08-28 Genomatica Inc Mikrooganismen und verfahren für die kohlenstoffwirksame biosynthese mek und 2-butanol
EP3190174A1 (de) 2009-08-05 2017-07-12 Genomatica, Inc. Aus muconsäureproduzierenden mikroorganismen gewonnene halbsynthetische terephthalsäure
US8715971B2 (en) 2009-09-09 2014-05-06 Genomatica, Inc. Microorganisms and methods for the co-production of isopropanol and 1,4-butanediol
KR20120083908A (ko) 2009-10-13 2012-07-26 게노마티카 인코포레이티드 1,4-부탄다이올, 4-하이드록시부탄알, 4-하이드록시부티릴-ｃｏａ, 푸트레신 및 관련 화합물의 제조를 위한 미생물 및 관련 방법
KR20180014240A (ko) 2009-10-23 2018-02-07 게노마티카 인코포레이티드 아닐린의 제조를 위한 미생물
KR20120120493A (ko) 2009-12-10 2012-11-01 게노마티카 인코포레이티드 합성 가스 또는 기타 가스상 탄소원 및 메탄올을 1,3-부탄디올로 변환하는 방법 및 변환용 유기체
JP2013517796A (ja) 2010-01-29 2013-05-20 ジェノマティカ・インコーポレイテッド ｐ−トルイル酸およびテレフタル酸を生合成するための方法および微生物
US8445244B2 (en) 2010-02-23 2013-05-21 Genomatica, Inc. Methods for increasing product yields
US8048661B2 (en) 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
CA2797409C (en) 2010-05-05 2019-12-24 Genomatica, Inc. Microorganisms and methods for the biosynthesis of butadiene
PH12013500158A1 (en) 2010-07-26 2013-03-11 Genomatica Inc Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene
EP3628676A1 (de) * 2018-09-28 2020-04-01 Université de Montpellier Modifizierte peptide und deren verwendungen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69016284T2 (de) * 1989-07-04 1995-05-24 Lepetit Spa Antibiotikum GE 22270, Faktoren A1,A2,A3 und H.

Also Published As

Publication number Publication date
EP0494078A1 (de) 1992-07-08
WO1992012172A1 (en) 1992-07-23
FI932944L (fi) 1993-06-24
KR930703355A (ko) 1993-11-29
JP3183508B2 (ja) 2001-07-09
FI932944A7 (fi) 1993-06-24
NZ241216A (en) 1994-04-27
DE69201236T2 (de) 1995-06-01
HU224072B1 (hu) 2005-05-30
HU9301941D0 (en) 1993-09-28
KR100225763B1 (ko) 1999-10-15
AU662122B2 (en) 1995-08-24
ES2067325T3 (es) 1995-03-16
EP0565567A1 (de) 1993-10-20
MX9200015A (es) 1992-07-31
DE69201236D1 (de) 1995-03-02
IE920005A1 (en) 1992-07-15
US5599791A (en) 1997-02-04
JPH06504768A (ja) 1994-06-02
IL100572A0 (en) 1992-09-06
AU1154492A (en) 1992-08-17
HUT64085A (en) 1993-11-29
EP0565567B1 (de) 1995-01-18
FI932944A0 (fi) 1993-06-24
CA2093219C (en) 2002-04-09
ZA927B (en) 1992-09-30
IL100572A (en) 1997-01-10
CN1063110A (zh) 1992-07-29
CA2093219A1 (en) 1992-07-04

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Legal Events

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