ATE117986T1 - Oxysulfonylharnstoff-acat-inhibitoren. - Google Patents

Oxysulfonylharnstoff-acat-inhibitoren.

Info

Publication number: ATE117986T1
Authority: AT; Austria
Prior art keywords: straight; carbon atoms; group; phenyl; substituted
Prior art date: 1990-11-09

Application number

AT92900693T

Other languages

English (en)

Inventor

Joseph Armand Picard

Drago Robert Sliskovic

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-11-09

Filing date

1991-11-05

Publication date

1995-02-15

1991-11-05 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

1995-02-15 Application granted granted Critical

1995-02-15 Publication of ATE117986T1 publication Critical patent/ATE117986T1/de

Links

-1 OXYSULFONYL UREA Chemical class 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1
125000004432 carbon atom Chemical group C* 0.000 abstract 4
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
125000000217 alkyl group Chemical group 0.000 abstract 2
125000003710 aryl alkyl group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000001183 hydrocarbyl group Chemical group 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000002950 monocyclic group Chemical group 0.000 abstract 2
125000001624 naphthyl group Chemical group 0.000 abstract 2
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
208000035150 Hypercholesterolemia Diseases 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
125000002618 bicyclic heterocycle group Chemical group 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C307/02—Monoamides of sulfuric acids or esters thereof, e.g. sulfamic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Diabetes (AREA)
Veterinary Medicine (AREA)
Obesity (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Hydrogenated Pyridines (AREA)
Pyridine Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Furan Compounds (AREA)
Steroid Compounds (AREA)

AT92900693T 1990-11-09 1991-11-05 Oxysulfonylharnstoff-acat-inhibitoren. ATE117986T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US61124590A	1990-11-09	1990-11-09
US07/736,678 US5198466A (en)	1990-11-09	1991-07-26	Oxysulfonyl urea acat inhibitors

Publications (1)

Publication Number	Publication Date
ATE117986T1 true ATE117986T1 (de)	1995-02-15

Family

ID=27086472

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92900693T ATE117986T1 (de)	1990-11-09	1991-11-05	Oxysulfonylharnstoff-acat-inhibitoren.

Country Status (16)

Country	Link
US (2)	US5198466A (de)
EP (1)	EP0556308B1 (de)
JP (1)	JP3177245B2 (de)
AT (1)	ATE117986T1 (de)
AU (1)	AU652207B2 (de)
CA (1)	CA2094808C (de)
DE (1)	DE69107217T2 (de)
DK (1)	DK0556308T3 (de)
ES (1)	ES2070623T3 (de)
GR (1)	GR3015648T3 (de)
IE (1)	IE65913B1 (de)
MX (1)	MX9101986A (de)
NZ (1)	NZ240509A (de)
PT (1)	PT99465B (de)
WO (1)	WO1992008692A1 (de)
ZA (1)	ZA918888B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5198466A (en) *	1990-11-09	1993-03-30	Warner-Lambert Company	Oxysulfonyl urea acat inhibitors
US5491172A (en) *	1993-05-14	1996-02-13	Warner-Lambert Company	N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents
IL109431A (en) *	1993-05-14	2001-01-11	Warner Lambert Co	Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds
WO1995024494A1 (en) *	1994-03-09	1995-09-14	Abbott Laboratories	Humanized milk
US5750176A (en) *	1994-03-09	1998-05-12	Abbott Laboratories	Transgenic non-human mammal milk comprising 2'-fucosyl-lactose
US6204431B1 (en)	1994-03-09	2001-03-20	Abbott Laboratories	Transgenic non-human mammals expressing heterologous glycosyltransferase DNA sequences produce oligosaccharides and glycoproteins in their milk
AU692841B2 (en) *	1994-03-09	1998-06-18	Abbott Laboratories	Transgenic animals producing oligosaccharides and glycoconjugates
US5510379A (en) *	1994-12-19	1996-04-23	Warner-Lambert Company	Sulfonate ACAT inhibitors
US5622577A (en) *	1995-08-28	1997-04-22	Delco Electronics Corp.	Rapid prototyping process and cooling chamber therefor
AU1735497A (en) *	1996-02-26	1997-09-10	Sumitomo Pharmaceuticals Company, Limited	Sulfonylureidopyrazole derivatives
CA2369967A1 (en) *	2001-02-12	2002-08-12	Joseph Anthony Cornicelli	Methods of treating nuclear factor-kappa b mediated diseases and disorders
EP1281399A3 (de) *	2001-08-01	2004-02-11	Warner-Lambert Company	Hemmer mit doppelter Wirkung auf Wachsester- und Cholesterylestersynthese zur Hemmung der Sebumproduktion

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4191553A (en) *	1978-03-02	1980-03-04	E. I. Du Pont De Nemours And Company	Herbicidal sulfamates
US4394153A (en) *	1980-07-11	1983-07-19	E. I. Du Pont De Nemours And Company	Herbicidal aryl esters of N-[(heterocyclic)-aminocarbonyl]sulfamic acid
US4581059A (en) *	1982-11-05	1986-04-08	E. I. Du Pont De Nemours And Company	Herbicidal phenoxy esters of N-(heterocyclic)aminocarbonyl)sulfamic acid
US4678500A (en) *	1984-06-29	1987-07-07	E. I. Du Pont De Nemours And Company	Herbicidal 2,6-disubstituted benzylsulfonamides and benzenesulfamates
DE3816703A1 (de) *	1988-05-17	1989-11-30	Hoechst Ag	Heterocyclisch substituierte phenoxysulfonylharnstoffe, verfahren zu ihrer herstellung und ihre verwendung als herbizide oder pflanzenwachstumsregulatoren
DE3942465A1 (de) *	1989-12-22	1991-06-27	Bayer Ag	Neue isocyanatoalkylsulfonate und ein verfahren zu deren herstellung
US5198466A (en) *	1990-11-09	1993-03-30	Warner-Lambert Company	Oxysulfonyl urea acat inhibitors
US5220041A (en) *	1991-03-04	1993-06-15	Eastman Kodak Company	Sulfonate ester

1991
- 1991-07-26 US US07/736,678 patent/US5198466A/en not_active Expired - Lifetime
- 1991-11-05 DK DK92900693.0T patent/DK0556308T3/da active
- 1991-11-05 EP EP92900693A patent/EP0556308B1/de not_active Expired - Lifetime
- 1991-11-05 AU AU90701/91A patent/AU652207B2/en not_active Ceased
- 1991-11-05 JP JP50186692A patent/JP3177245B2/ja not_active Expired - Fee Related
- 1991-11-05 AT AT92900693T patent/ATE117986T1/de not_active IP Right Cessation
- 1991-11-05 CA CA002094808A patent/CA2094808C/en not_active Expired - Fee Related
- 1991-11-05 WO PCT/US1991/008216 patent/WO1992008692A1/en not_active Ceased
- 1991-11-05 ES ES92900693T patent/ES2070623T3/es not_active Expired - Lifetime
- 1991-11-05 DE DE69107217T patent/DE69107217T2/de not_active Expired - Fee Related
- 1991-11-07 NZ NZ24050991A patent/NZ240509A/en not_active IP Right Cessation
- 1991-11-08 MX MX9101986A patent/MX9101986A/es not_active IP Right Cessation
- 1991-11-08 PT PT99465A patent/PT99465B/pt not_active IP Right Cessation
- 1991-11-08 ZA ZA918888A patent/ZA918888B/xx unknown
- 1991-11-08 IE IE391191A patent/IE65913B1/en not_active IP Right Cessation
1992
- 1992-12-01 US US07/984,028 patent/US5364882A/en not_active Expired - Fee Related
1995
- 1995-04-03 GR GR950400792T patent/GR3015648T3/el unknown

Also Published As

Publication number	Publication date
IE65913B1 (en)	1995-11-29
CA2094808C (en)	2003-10-07
JP3177245B2 (ja)	2001-06-18
GR3015648T3 (en)	1995-07-31
JPH06501486A (ja)	1994-02-17
WO1992008692A1 (en)	1992-05-29
AU652207B2 (en)	1994-08-18
ZA918888B (en)	1993-05-10
IE913911A1 (en)	1992-05-20
NZ240509A (en)	1994-07-26
AU9070191A (en)	1992-06-11
ES2070623T3 (es)	1995-06-01
US5364882A (en)	1994-11-15
PT99465A (pt)	1992-10-30
EP0556308B1 (de)	1995-02-01
DE69107217D1 (en)	1995-03-16
MX9101986A (es)	1992-06-01
DK0556308T3 (da)	1995-06-26
CA2094808A1 (en)	1992-05-10
US5198466A (en)	1993-03-30
DE69107217T2 (de)	1995-05-24
PT99465B (pt)	1999-02-26
EP0556308A1 (de)	1993-08-25

Legal Events

Date	Code	Title	Description
2007-08-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
HUP9802814A2 (hu)	1999-10-28	Szelektív béta3 adrenergiás agonista hatású vegyületek, e vegyületeket tartalmazó gyógyászati készítmények, eljárás előállításukra és alkalmazásuk
DE69133299D1 (de)	2003-09-04	Aminosulfonylcarbamate
YU64092A (sh)	1995-03-27	Fluoralkoksibenzamino derivati heterocikličnih jedinjenja koja sadrže azot
ATE94065T1 (de)	1993-09-15	Diazepine enthaltende pharmazeutische zusammensetzungen mit plaettchen aktivierender faktor (paf)-antagonistischer wirkung.
IL97900A (en)	1997-04-15	Substituted 5-(2- ( ( 2-aryl- 2-hydroxyethyl) amino) propyl)-1, 3-benzodioxoles and a process for producing them
DK160877C (da)	1991-10-14	Fremgangsmaade til fremstilling af 2-penemforbindelser
EA199800141A1 (ru)	1998-08-27	Гетероциклические соединения
ATE117986T1 (de)	1995-02-15	Oxysulfonylharnstoff-acat-inhibitoren.
DK159148C (da)	1991-02-11	Analogifremgangsmaade til fremstilling af tranexamsyrederivater
FI832092L (fi)	1983-12-15	1-aryloxi-2,3,4,5-tetrahydro-3-bensazepiner, foerfarande foer framstaellning av dem och anvaendning av dem som laekemedel
ES2123756T3 (es)	1999-01-16	Derivados de piperazina.
ES2190809T3 (es)	2003-08-16	Compuestos de quinolina y quinazolina utiles en terapia.
MX9301045A (es)	1993-09-01	Procedimiento para preparar antagonistas receptores de fibrinogeno.
IE56000B1 (en)	1991-03-13	1-arylcyclobutylalkylamine compounds
ES467069A1 (es)	1979-10-16	Un procedimiento para la preparacion de nuevos derivados de 1-3-bencenodimetanol
ES8706628A1 (es)	1987-07-01	Procedimiento para la preparacion de 2-(piridil e imidazolil)-indoles.
ES2104688T3 (es)	1997-10-16	Un procedimiento para la preparacion de un compuesto de tio-3-cefem 3-sustituido.
AU2175083A (en)	1984-06-07	2-(substituted amino)-pyrimid-4-one derivatives
ATE116291T1 (de)	1995-01-15	Oxysulfonylcarbamate.
PT92494A (pt)	1990-06-29	Processo para a preparacao de novos derivados do indol
ES8405020A1 (es)	1984-05-16	Un procedimiento para la preparacion de derivados de fosfolipidos.
EA199800287A1 (ru)	1998-08-27	Производные пептидов
DK157863C (da)	1990-08-06	Analogifremgangsmaade til fremstilling af 4-substituerede quinazoliner