ATE118037T1 - Rekombinanter natürlicher killerzellen-aktivator. - Google Patents

Rekombinanter natürlicher killerzellen-aktivator.

Info

Publication number
ATE118037T1
ATE118037T1 AT89116105T AT89116105T ATE118037T1 AT E118037 T1 ATE118037 T1 AT E118037T1 AT 89116105 T AT89116105 T AT 89116105T AT 89116105 T AT89116105 T AT 89116105T AT E118037 T1 ATE118037 T1 AT E118037T1
Authority
AT
Austria
Prior art keywords
natural killer
killer cell
recombinant natural
activating factor
cell activating
Prior art date
Application number
AT89116105T
Other languages
English (en)
Inventor
Kentaro Yoshimatsu
Yukio Ohya
Yasushi Shikata
Isao Tanaka
Yoshikazu Hasegawa
Toshio Seto
Toshiaki Osawa
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Application granted granted Critical
Publication of ATE118037T1 publication Critical patent/ATE118037T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Beans For Foods Or Fodder (AREA)
  • Meat, Egg Or Seafood Products (AREA)
AT89116105T 1988-08-31 1989-08-31 Rekombinanter natürlicher killerzellen-aktivator. ATE118037T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP21759988 1988-08-31

Publications (1)

Publication Number Publication Date
ATE118037T1 true ATE118037T1 (de) 1995-02-15

Family

ID=16706821

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89116105T ATE118037T1 (de) 1988-08-31 1989-08-31 Rekombinanter natürlicher killerzellen-aktivator.

Country Status (10)

Country Link
US (2) US5185431A (de)
EP (1) EP0357067B1 (de)
KR (1) KR900003371A (de)
AT (1) ATE118037T1 (de)
AU (1) AU4009789A (de)
CA (1) CA1335360C (de)
DE (1) DE68920931T2 (de)
DK (1) DK424989A (de)
FI (1) FI893833A7 (de)
NO (1) NO893452L (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5457038A (en) * 1988-11-10 1995-10-10 Genetics Institute, Inc. Natural killer stimulatory factor
US5811523A (en) 1988-11-10 1998-09-22 Trinchieri; Giorgio Antibodies to natural killer stimulatory factor
ATE140483T1 (de) * 1988-11-10 1996-08-15 Genetics Inst Natürlicher killerzellen-stimulationsfaktor
US6683046B1 (en) 1989-12-22 2004-01-27 Hoffmann-La Roche Inc. Purification and characterization of cytotoxic lymphocyte maturation factor and monoclonal antibodies thereto
JP3479539B2 (ja) 1992-04-10 2003-12-15 エーザイ株式会社 ヒトアンチトロンビンｉｉｉ変異体
AU2818695A (en) * 1995-06-06 1996-12-24 Human Genome Sciences, Inc. Natural killer cell enhancing factor c
US6255079B1 (en) 1995-06-06 2001-07-03 Human Genome Sciences, Inc. Polynucleotides encoding natural killer cell enhancing factor C
WO1996040947A1 (en) * 1995-06-07 1996-12-19 Washington University Recombinant bacterial system with environmentally limited viability
EP0937147A1 (de) * 1996-04-03 1999-08-25 Human Genome Sciences, Inc. Menschlicher natürlicher killerzellen-aktivator
US6448044B2 (en) 1996-04-03 2002-09-10 Human Genome Sciences, Inc. DNA encoding human natural killer cell activating factor II
US7026456B1 (en) 1998-01-23 2006-04-11 Hoffman-La Roche, Inc. Antibodies against human IL-12
EP1930438A1 (de) * 2006-12-07 2008-06-11 Academisch Medisch Centrum bij de Universiteit van Amsterdam Transkriptionsfaktor zur Aktivierung von Killerzellen, Differenzierung und dessen Verwendungen
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
CN114736268B (zh) * 2022-03-01 2024-09-27 吉林农业大学 一种提高活性肽ace抑制率的修饰方法、ace抑制肽及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58110548A (ja) * 1981-12-24 1983-07-01 Asahi Chem Ind Co Ltd 新規な生理活性ペプチド
JPS6197224A (ja) * 1984-10-19 1986-05-15 Eisai Co Ltd 新規なリンホカイン

Also Published As

Publication number Publication date
CA1335360C (en) 1995-04-25
US5316933A (en) 1994-05-31
NO893452L (no) 1990-03-01
EP0357067A2 (de) 1990-03-07
DE68920931T2 (de) 1995-07-06
DE68920931D1 (de) 1995-03-16
US5185431A (en) 1993-02-09
EP0357067A3 (de) 1991-08-21
FI893833A0 (fi) 1989-08-15
DK424989A (da) 1990-03-01
FI893833A7 (fi) 1990-03-01
EP0357067B1 (de) 1995-02-01
AU4009789A (en) 1990-03-08
KR900003371A (ko) 1990-03-26
NO893452D0 (no) 1989-08-29
DK424989D0 (da) 1989-08-29

Similar Documents

Publication Publication Date Title
DE68920931D1 (de) Rekombinanter natürlicher Killerzellen-Aktivator.
KR850004273A (ko) 안정성이 증대된 재조합 감마 인터페론 및 그의 제조방법
IS5087A (is) Stöðugar interferónlyfjablöndur á vökvaformi
TW343198B (en) Cyclopeptides useful as adhesion inhibitors, process for the preparation thereof, and pharmaceutical composition containing them
AU6819294A (en) Oral drug delivery compositions and methods
ATE493998T1 (de) Pharmazeutische zusammensetzung mit einem exendin-4-peptid
ATE173478T1 (de) Varianten des pankreatischen rinder- trypsininhibitors, deren herstellung und verwendung
DK0679092T3 (da) Cytokindæmpende midler
CA2094027A1 (en) Osteogenic peptides
KR950703999A (ko) 변성된 인슐린-유사 성장인자(modified insulin-like growth factors)
LV10302A (lv) Plazmidas iegusanas panemiens plazmida audu plazminogena aktivators
ATE121755T1 (de) Deletionsanaloga von magaininpeptiden.
FI101938B1 (fi) Polypeptidijohdannaisia
ATE63823T1 (de) Pharmazeutische zubereitungsformen zur stabilisierung von interferon alpha.
IL88378A (en) Human interferon-gamma binding proteins their manufacture and pharmaceutical compositions comprising them
DE59108947D1 (de) Neues menschliches, rekombinantes interferon gamma
DE3650035D1 (de) THF-Zusammensetzungen.
MY104088A (en) Peptide-drugs compositions containing (alpha)-aminoboroic acid derivatives.
CA2247998A1 (en) Fragments of cr1 and their use
KR840007567A (ko) 펩티드의 제조방법
AU4405689A (en) New limphokines, dna sequences coding for said limphokines and pharmaceutical compositions containing said limphokines
UY25951A1 (es) Polipéptidos receptores p75 (tipo ii) de factor de necrosis tumoral purificados

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties