ATE118548T1 - Herstellungsverfahren von zuckernukleotiden mittels rekombinantverfahrens. - Google Patents
Herstellungsverfahren von zuckernukleotiden mittels rekombinantverfahrens.Info
- Publication number
- ATE118548T1 ATE118548T1 AT87902918T AT87902918T ATE118548T1 AT E118548 T1 ATE118548 T1 AT E118548T1 AT 87902918 T AT87902918 T AT 87902918T AT 87902918 T AT87902918 T AT 87902918T AT E118548 T1 ATE118548 T1 AT E118548T1
- Authority
- AT
- Austria
- Prior art keywords
- synthesis
- sugar
- nucleotides
- sugar nucleotides
- recombinant
- Prior art date
Links
- 239000002773 nucleotide Substances 0.000 title abstract 7
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 125000003729 nucleotide group Chemical group 0.000 abstract 6
- 230000015572 biosynthetic process Effects 0.000 abstract 5
- 238000003786 synthesis reaction Methods 0.000 abstract 5
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- HSCJRCZFDFQWRP-UHFFFAOYSA-N Uridindiphosphoglukose Natural products OC1C(O)C(O)C(CO)OC1OP(O)(=O)OP(O)(=O)OCC1C(O)C(O)C(N2C(NC(=O)C=C2)=O)O1 HSCJRCZFDFQWRP-UHFFFAOYSA-N 0.000 abstract 2
- 239000013612 plasmid Substances 0.000 abstract 2
- MVMSCBBUIHUTGJ-UHFFFAOYSA-N 10108-97-1 Natural products C1=2NC(N)=NC(=O)C=2N=CN1C(C(C1O)O)OC1COP(O)(=O)OP(O)(=O)OC1OC(CO)C(O)C(O)C1O MVMSCBBUIHUTGJ-UHFFFAOYSA-N 0.000 abstract 1
- 101100409539 Caenorhabditis elegans pas-7 gene Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 241000588724 Escherichia coli Species 0.000 abstract 1
- MVMSCBBUIHUTGJ-GDJBGNAASA-N GDP-alpha-D-mannose Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H]1O)O)N1C=2N=C(NC(=O)C=2N=C1)N)OP(O)(=O)OP(O)(=O)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O MVMSCBBUIHUTGJ-GDJBGNAASA-N 0.000 abstract 1
- 241000589774 Pseudomonas sp. Species 0.000 abstract 1
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- HSCJRCZFDFQWRP-JZMIEXBBSA-N UDP-alpha-D-glucose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OP(O)(=O)OP(O)(=O)OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(NC(=O)C=C2)=O)O1 HSCJRCZFDFQWRP-JZMIEXBBSA-N 0.000 abstract 1
- HDYANYHVCAPMJV-UHFFFAOYSA-N Uridine diphospho-D-glucuronic acid Natural products O1C(N2C(NC(=O)C=C2)=O)C(O)C(O)C1COP(O)(=O)OP(O)(=O)OC1OC(C(O)=O)C(O)C(O)C1O HDYANYHVCAPMJV-UHFFFAOYSA-N 0.000 abstract 1
- 241000589636 Xanthomonas campestris Species 0.000 abstract 1
- 241001148118 Xanthomonas sp. Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
- HDYANYHVCAPMJV-USQUEEHTSA-N udp-glucuronic acid Chemical compound O([P@](O)(=O)O[P@](O)(=O)OC[C@H]1[C@@H]([C@H]([C@@H](O1)N1C(NC(=O)C=C1)=O)O)O)[C@H]1O[C@@H](C(O)=O)[C@H](O)[C@@H](O)[C@@H]1O HDYANYHVCAPMJV-USQUEEHTSA-N 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
- 229920001285 xanthan gum Polymers 0.000 abstract 1
- 229940082509 xanthan gum Drugs 0.000 abstract 1
- 235000010493 xanthan gum Nutrition 0.000 abstract 1
- 239000000230 xanthan gum Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/305—Pyrimidine nucleotides
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84334986A | 1986-03-24 | 1986-03-24 | |
| US2909187A | 1987-03-23 | 1987-03-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE118548T1 true ATE118548T1 (de) | 1995-03-15 |
Family
ID=26704524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87902918T ATE118548T1 (de) | 1986-03-24 | 1987-03-24 | Herstellungsverfahren von zuckernukleotiden mittels rekombinantverfahrens. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5824472A (de) |
| EP (1) | EP0380470B1 (de) |
| JP (1) | JP3074629B2 (de) |
| AT (1) | ATE118548T1 (de) |
| CA (1) | CA1340411C (de) |
| DE (1) | DE3751066T2 (de) |
| NO (1) | NO179875C (de) |
| WO (1) | WO1987005937A1 (de) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE128731T1 (de) * | 1986-03-24 | 1995-10-15 | Texaco Development Corp | Erzeugung von xanthangummi durch rekombinant-dns. |
| ATE295886T1 (de) * | 1995-03-03 | 2005-06-15 | Forschungszentrum Juelich Gmbh | Photometrischer test zur bestimmung von pyrophosphat nach dessen enzymatischer umsetzung |
| US5928932A (en) * | 1996-04-03 | 1999-07-27 | Midwest Research Institute | Isolated gene encoding an enzyme with UDP-glucose pyrophosphorylase and phosphoglucomutase activities from Cyclotella cryptica |
| CA2289109A1 (en) * | 1997-04-30 | 1998-11-05 | Genzyme Limited | Carbohydrate-deficient glycoprotein syndrome type i |
| RU2122570C1 (ru) * | 1997-07-07 | 1998-11-27 | Открытое акционерное общество "Завод им.Шаумяна" | Многоцелевая пластичная смазка для узлов трения машин и механизмов |
| DE19735994A1 (de) * | 1997-08-19 | 1999-02-25 | Piepersberg Wolfgang Prof Dr | Verfahren zur enzymatischen Synthese von Guanosindiphosphat-6-desoxyhexosen und deren Verwendung zur Herstellung von Oligosacchariden |
| US6399859B1 (en) * | 1997-12-10 | 2002-06-04 | Pioneer Hi-Bred International, Inc. | Plant uridine diphosphate-glucose dehydrogenase genes, proteins, and uses thereof |
| AU2321499A (en) * | 1998-01-15 | 1999-08-02 | E.I. Du Pont De Nemours And Company | Plant phosphoglucomutase homologs |
| US6706951B1 (en) | 1998-08-17 | 2004-03-16 | Pioneer Hi-Bred International, Inc. | Maize nucleic acid encoding a GDP-mannose pyrophosphorylase |
| US7508608B2 (en) | 2004-11-17 | 2009-03-24 | Illumina, Inc. | Lithographically fabricated holographic optical identification element |
| US7619819B2 (en) | 2002-08-20 | 2009-11-17 | Illumina, Inc. | Method and apparatus for drug product tracking using encoded optical identification elements |
| US7901630B2 (en) | 2002-08-20 | 2011-03-08 | Illumina, Inc. | Diffraction grating-based encoded microparticle assay stick |
| US7923260B2 (en) | 2002-08-20 | 2011-04-12 | Illumina, Inc. | Method of reading encoded particles |
| US7164533B2 (en) | 2003-01-22 | 2007-01-16 | Cyvera Corporation | Hybrid random bead/chip based microarray |
| US7092160B2 (en) | 2002-09-12 | 2006-08-15 | Illumina, Inc. | Method of manufacturing of diffraction grating-based optical identification element |
| US9453251B2 (en) | 2002-10-08 | 2016-09-27 | Pfenex Inc. | Expression of mammalian proteins in Pseudomonas fluorescens |
| BRPI0506917A (pt) | 2004-01-16 | 2007-06-05 | Dow Global Technologies Inc | expressão de proteìnas de mamìferos em pseudomonas fluorescens |
| EP2412816B1 (de) | 2004-07-26 | 2014-12-03 | Pfenex Inc. | Verfahren zur verbesserten Proteinexpression durch Strain-Engineering |
| US7604173B2 (en) | 2004-11-16 | 2009-10-20 | Illumina, Inc. | Holographically encoded elements for microarray and other tagging labeling applications, and method and apparatus for making and reading the same |
| JP4639904B2 (ja) | 2005-03-30 | 2011-02-23 | チッソ株式会社 | 蛍光活性を有するルシフェラーゼの活性増強方法 |
| JP4609177B2 (ja) | 2005-04-28 | 2011-01-12 | チッソ株式会社 | カルシウム結合型発光蛋白質溶液の発光時間延長方法 |
| GB0610498D0 (en) * | 2006-05-26 | 2006-07-05 | Univ York | Modified molecule |
| EP2615172A1 (de) | 2007-04-27 | 2013-07-17 | Pfenex Inc. | Schnellscreeningverfahren für Bakterienwirte zur Identifizierung bestimmter Stämme mit verbessertem Ertrag und/oder verbesserter Qualität bei der Expression heterologer Proteine |
| US9580719B2 (en) | 2007-04-27 | 2017-02-28 | Pfenex, Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
| WO2013013244A2 (en) * | 2011-07-21 | 2013-01-24 | The Regents Of The University Of California | Chemoenzymatic synthesis of heparin and haparan sulfate analogs |
| US9290530B2 (en) | 2011-07-21 | 2016-03-22 | The Regents Of The University Of California | Chemoenzymatic synthesis of heparin and heparan sulfate analogs |
| US20150225758A1 (en) * | 2011-11-08 | 2015-08-13 | University Of Georgia Research Foundation, Inc. | Genetically modified cells and methods for making activated sugar-nucleotides |
| EP2905341B1 (de) * | 2014-02-07 | 2020-04-29 | Jennewein Biotechnologie GmbH | Verfahren zur Herstellung von GDP-Fucose mit Hilfe von Nukleotid-Zuckertransporter und rekombinante Mikroorganismus-Wirtszellen dafür |
| CN110229771B (zh) * | 2018-03-06 | 2021-02-19 | 廊坊梅花生物技术开发有限公司 | 菌株、其构建方法及应用 |
| CN111518825B (zh) * | 2020-04-30 | 2022-10-11 | 浙江工业大学 | 一种多基因组合表达制备蛹虫草多糖的方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4296203A (en) * | 1977-11-15 | 1981-10-20 | Pfizer Inc. | Xanthomonas bipolymer for use in displacement of oil from partially depleted reservoirs |
| CA1167403A (en) * | 1979-07-10 | 1984-05-15 | Unilever Limited | Microbial heteropolysaccharide |
| US4407951A (en) * | 1980-07-14 | 1983-10-04 | Standard Oil Company (Indiana) | Xanthomonas campestris ATCC 31600 and process for use |
| DE3274467D1 (en) * | 1981-05-22 | 1987-01-15 | Kelco Biospecialties Ltd | Production of xanthan having a low pyruvate content |
| US4713449A (en) * | 1985-08-06 | 1987-12-15 | Getty Scientific Development Company | Polysaccharide polymer made by xanthomonas |
| ATE128731T1 (de) * | 1986-03-24 | 1995-10-15 | Texaco Development Corp | Erzeugung von xanthangummi durch rekombinant-dns. |
-
1987
- 1987-03-24 EP EP87902918A patent/EP0380470B1/de not_active Expired - Lifetime
- 1987-03-24 AT AT87902918T patent/ATE118548T1/de not_active IP Right Cessation
- 1987-03-24 CA CA000532844A patent/CA1340411C/en not_active Expired - Fee Related
- 1987-03-24 DE DE3751066T patent/DE3751066T2/de not_active Expired - Fee Related
- 1987-03-24 WO PCT/US1987/000605 patent/WO1987005937A1/en not_active Ceased
- 1987-11-23 NO NO874879A patent/NO179875C/no unknown
-
1995
- 1995-06-06 US US08/467,145 patent/US5824472A/en not_active Expired - Lifetime
-
1999
- 1999-04-06 JP JP11098725A patent/JP3074629B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NO874879D0 (no) | 1987-11-23 |
| DE3751066T2 (de) | 1995-06-08 |
| CA1340411C (en) | 1999-03-02 |
| EP0380470A4 (de) | 1990-06-05 |
| NO179875B (no) | 1996-09-23 |
| NO874879L (no) | 1988-01-25 |
| NO179875C (no) | 1997-01-08 |
| EP0380470A1 (de) | 1990-08-08 |
| EP0380470B1 (de) | 1995-02-15 |
| DE3751066D1 (de) | 1995-03-23 |
| WO1987005937A1 (en) | 1987-10-08 |
| US5824472A (en) | 1998-10-20 |
| JP3074629B2 (ja) | 2000-08-07 |
| JP2000032982A (ja) | 2000-02-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EEIH | Change in the person of patent owner | ||
| EEIH | Change in the person of patent owner | ||
| REN | Ceased due to non-payment of the annual fee |