ATE119031T1 - Arzneimittelträger. - Google Patents

Arzneimittelträger.

Info

Publication number
ATE119031T1
ATE119031T1 AT88118025T AT88118025T ATE119031T1 AT E119031 T1 ATE119031 T1 AT E119031T1 AT 88118025 T AT88118025 T AT 88118025T AT 88118025 T AT88118025 T AT 88118025T AT E119031 T1 ATE119031 T1 AT E119031T1
Authority
AT
Austria
Prior art keywords
drug carriers
drug
less
particle diameter
mean particle
Prior art date
Application number
AT88118025T
Other languages
English (en)
Inventor
Makoto Sugiyama
Atsuhiko Okita
Junzo Seki
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Application granted granted Critical
Publication of ATE119031T1 publication Critical patent/ATE119031T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Lubricants (AREA)
  • Indole Compounds (AREA)
AT88118025T 1987-10-28 1988-10-28 Arzneimittelträger. ATE119031T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP27277087 1987-10-28

Publications (1)

Publication Number Publication Date
ATE119031T1 true ATE119031T1 (de) 1995-03-15

Family

ID=17518498

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88118025T ATE119031T1 (de) 1987-10-28 1988-10-28 Arzneimittelträger.

Country Status (15)

Country Link
EP (1) EP0315079B1 (de)
KR (1) KR960013281B1 (de)
CN (1) CN1048182C (de)
AT (1) ATE119031T1 (de)
AU (1) AU623342B2 (de)
BE (1) BE1001760A5 (de)
CA (1) CA1333993C (de)
CH (1) CH677605A5 (de)
DE (1) DE3853191T2 (de)
ES (1) ES2012561A6 (de)
FR (1) FR2622442B1 (de)
GB (1) GB2211408B (de)
IL (1) IL88076A (de)
IT (1) IT1224596B (de)
NL (1) NL193340C (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0148748B1 (ko) 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
ES2052016T3 (es) * 1988-09-29 1994-07-01 Shiseido Co Ltd Composicion emulsionada.
JP2785981B2 (ja) * 1989-11-20 1998-08-13 株式会社資生堂 乳化組成物
TW211015B (de) * 1990-01-11 1993-08-11 Nippon Shinyaku Co Ltd
AU665931B2 (en) * 1990-11-06 1996-01-25 Nippon Shinyaku Co. Ltd. Lyophilized preparation and production thereof
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
IL101387A (en) * 1992-03-26 1999-11-30 Pharmos Ltd Emulsion with enhanced topical and/or transdermal systemic effect utilizing submicron oil droplets
BR9201168A (pt) * 1992-04-02 1994-04-12 Zerbini E J Fundacao Microemulsoes usadas como velculo para carregar quimioterapicos as celulas neoplasicas
HK1004520A1 (en) 1992-05-13 1998-11-27 Novartis Ag Ophthalmic compositions containing a cyclosporin
PT589843E (pt) 1992-09-25 2002-04-29 Novartis Ag Composicoes farmaceuticas contendo ciclosporinas
US6113921A (en) * 1993-03-23 2000-09-05 Pharmos Corp. Topical and transdermal delivery system utilizing submicron oil spheres
US5576016A (en) * 1993-05-18 1996-11-19 Pharmos Corporation Solid fat nanoemulsions as drug delivery vehicles
US5961970A (en) * 1993-10-29 1999-10-05 Pharmos Corporation Submicron emulsions as vaccine adjuvants
FI963297L (fi) * 1994-02-25 1996-10-18 Takeda Chemical Industries Ltd Antifungaalisia triatsolijohdannaisia sisältävät emulsiot
US5851510A (en) * 1994-05-16 1998-12-22 The Board Of Regents Of The University Of Michigan Hepatocyte-selective oil-in-water emulsion
SK164796A3 (en) 1994-11-03 1997-06-04 Dresden Arzneimittel Novel cyclosporine preparation forms for oral administration of and process for producing them
EP0808154B1 (de) * 1995-02-06 2000-12-20 Elan Pharma International Limited Formulierungen von verbindungen als nanopartikel dispergiert in verdaubaren ölen oder fettsäuren
DE19544507B4 (de) 1995-11-29 2007-11-15 Novartis Ag Cyclosporin enthaltende Präparate
GB9601120D0 (en) 1996-01-19 1996-03-20 Sandoz Ltd Organic compounds
JP3136352B2 (ja) * 1996-01-22 2001-02-19 参天製薬株式会社 角結膜疾患治療剤
TR199802769T2 (xx) * 1996-07-02 1999-04-21 Novartis Consumer Health S.A. Terpenoid bileşikler ile antihistaminik bileşiklerin bir kombinasyonunu ihtiva eden topikal bileşim.
SK285019B6 (sk) 1997-01-30 2006-04-06 Novartis Ag Tvrdá želatínová tobolka
US6537561B1 (en) 1997-02-27 2003-03-25 Nippon Shinyaku Co., Ltd. Fat emulsion for oral administration
IL121647A (en) * 1997-08-28 2001-07-24 Pharmateam Dev Ltd Pharmaceutical compositions for the treatment of ocular inflammation comprising dexamethasone palmitate
GR20020100012A (el) * 2002-01-16 2003-09-24 Αγγελικη Κουρουνακη Το γουαιαζουλενιο για χρηση στην προληψη ή θεραπεια καθε τυπου υπερχοληστερολαιμιας, υπερλιπιδαιμιας και καθε διαταραχη λιπιδιων, σε ανθρωπους και ζωα
CN1297271C (zh) * 2003-09-30 2007-01-31 昆明紫健生物技术有限公司 草乌甲素脂肪乳输液及其生产方法
CN100386085C (zh) * 2003-12-17 2008-05-07 昆明紫健生物技术有限公司 一种防治肿瘤的脂肪乳输液及生产方法
US7871632B2 (en) * 2004-07-12 2011-01-18 Adventrx Pharmaceuticals, Inc. Compositions for delivering highly water soluble drugs
US20080274195A1 (en) 2005-07-18 2008-11-06 University Of Massachusetts Lowell Compositions and Methods for Making and Using Nanoemulsions
US9486408B2 (en) 2005-12-01 2016-11-08 University Of Massachusetts Lowell Botulinum nanoemulsions
SG177184A1 (en) 2006-12-01 2012-01-30 Anterios Inc Amphiphilic entity nanoparticles
SG179457A1 (en) 2006-12-01 2012-04-27 Anterios Inc Peptide nanoparticles and uses therefor
CN101765423B (zh) 2007-05-31 2014-08-06 安特里奥公司 核酸纳米粒子和其用途
WO2010079037A2 (de) * 2008-12-18 2010-07-15 Basf Se Wässrige dispersion umfassend pestizidpartikel und amphiphil
DE102010021688A1 (de) * 2010-05-27 2011-12-01 Qineva Gmbh & Co. Kg Verfahren zur Herstellung eines micellaren Wirkstoffkonzentrats
JP6166480B2 (ja) * 2013-12-11 2017-07-19 ヘルス−エバー バイオテック カンパニー リミテッド カロテノイドの医薬組成物
CN105483076B (zh) 2015-12-23 2019-01-25 中国科学院生物物理研究所 一种脂肪体的制备方法及其应用
MX2019005833A (es) 2016-11-21 2019-10-30 Eirion Therapeutics Inc Administracion transdermica de agentes grandes.
WO2023178519A1 (zh) * 2022-03-22 2023-09-28 乐普（北京）医疗器械股份有限公司 一种药物涂层、药物球囊及药物球囊制备方法与应用
CN115919759B (zh) * 2022-12-27 2025-03-18 沈阳药科大学 一种低聚集体眼用纳米制剂及其制备方法和用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2502951B1 (fr) * 1981-04-06 1985-12-06 Sandoz Sa Compositions pharmaceutiques topiques sous forme d'une micro-emulsion
DE3225848A1 (de) * 1982-07-07 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen Kortikoidhaltige zubereitung zur topischen applikation
DE3225706C2 (de) * 1982-07-09 1984-04-26 A. Nattermann & Cie GmbH, 5000 Köln Flüssige Wirkstofformulierungen in Form von Konzentraten für Mikroemulsionen
JPS59193814A (ja) * 1983-04-20 1984-11-02 Ajinomoto Co Inc アミノ酸含有脂肪乳剤
JPS60231609A (ja) * 1984-04-28 1985-11-18 Terumo Corp リポソ−ム製剤
DE3421468A1 (de) * 1984-06-08 1985-12-19 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung
DK482685D0 (da) * 1984-10-22 1985-10-21 Hope Nat Medical Center Fremgangsmaade til tilfoersel af micellulaere partikler, der indkapslerbilleddannende og kemoterapeutiske midler, til tumorer i et legeme
US4753788A (en) * 1985-01-31 1988-06-28 Vestar Research Inc. Method for preparing small vesicles using microemulsification
IL78929A0 (en) * 1985-07-29 1986-09-30 Abbott Lab Microemulsion compositions for parenteral administration
US5023271A (en) * 1985-08-13 1991-06-11 California Biotechnology Inc. Pharmaceutical microemulsions
JPS6348214A (ja) * 1986-08-18 1988-02-29 Morishita Seiyaku Kk １−〔２−（２，４−ジクロロフエニル）−３−メチル−１−ペンテニル〕−１ｈ−イミダゾ−ルを含有する水中油型脂肪乳剤
FR2608942B1 (fr) * 1986-12-31 1991-01-11 Centre Nat Rech Scient Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanocapsules

Also Published As

Publication number Publication date
CN1042080A (zh) 1990-05-16
CA1333993C (en) 1995-01-17
GB8825024D0 (en) 1988-11-30
DE3853191T2 (de) 1995-10-19
ES2012561A6 (es) 1990-04-01
BE1001760A5 (fr) 1990-02-27
EP0315079A1 (de) 1989-05-10
FR2622442A1 (fr) 1989-05-05
KR890006225A (ko) 1989-06-12
FR2622442B1 (fr) 1993-10-22
GB2211408A (en) 1989-07-05
AU2447288A (en) 1989-05-04
IL88076A0 (en) 1989-06-30
IT8848502A0 (it) 1988-10-27
IL88076A (en) 1993-01-14
AU623342B2 (en) 1992-05-14
IT1224596B (it) 1990-10-04
NL8802657A (nl) 1989-05-16
CH677605A5 (de) 1991-06-14
EP0315079B1 (de) 1995-03-01
DE3853191D1 (de) 1995-04-06
KR960013281B1 (ko) 1996-10-02
NL193340C (nl) 1999-07-02
CN1048182C (zh) 2000-01-12
GB2211408B (en) 1992-04-15
NL193340B (nl) 1999-03-01

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee