ATE120497T1 - Verfahren zur voraussage der wirksamkeit einer antineoplastichen behandlung bei einzelnen patienten. - Google Patents
Verfahren zur voraussage der wirksamkeit einer antineoplastichen behandlung bei einzelnen patienten.Info
- Publication number
- ATE120497T1 ATE120497T1 AT89304494T AT89304494T ATE120497T1 AT E120497 T1 ATE120497 T1 AT E120497T1 AT 89304494 T AT89304494 T AT 89304494T AT 89304494 T AT89304494 T AT 89304494T AT E120497 T1 ATE120497 T1 AT E120497T1
- Authority
- AT
- Austria
- Prior art keywords
- effectiveness
- individual patients
- expression
- predicting
- antineoplastic treatment
- Prior art date
Links
- 230000000118 anti-neoplastic effect Effects 0.000 title 1
- 229940034982 antineoplastic agent Drugs 0.000 abstract 2
- 239000002246 antineoplastic agent Substances 0.000 abstract 2
- 210000005170 neoplastic cell Anatomy 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 230000001105 regulatory effect Effects 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000011534 incubation Methods 0.000 abstract 1
- 230000000977 initiatory effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function
- Y10S436/813—Cancer
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19144988A | 1988-05-09 | 1988-05-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE120497T1 true ATE120497T1 (de) | 1995-04-15 |
Family
ID=22705545
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89304494T ATE120497T1 (de) | 1988-05-09 | 1989-05-04 | Verfahren zur voraussage der wirksamkeit einer antineoplastichen behandlung bei einzelnen patienten. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5427916A (de) |
| EP (1) | EP0341904B1 (de) |
| JP (1) | JPH0636759B2 (de) |
| AT (1) | ATE120497T1 (de) |
| DE (1) | DE68921918T2 (de) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69124254T2 (de) * | 1990-09-24 | 1997-06-12 | Catherine Anderson | Überprüfungsteste |
| DK0534640T3 (de) * | 1991-09-23 | 1997-03-17 | Pfizer | |
| US5411860A (en) * | 1992-04-07 | 1995-05-02 | The Johns Hopkins University | Amplification of human MDM2 gene in human tumors |
| EP0646174A1 (de) * | 1992-06-16 | 1995-04-05 | The Whittier Institute For Diabetes And Endocrinology | Rekombinante herstellung von saporin-enthaltenden proteinen |
| DK0646182T3 (da) * | 1992-06-18 | 1996-09-16 | Whittier Inst Diabetes & Endoc | Fremgangsmåde til påvisning af neoplastiske sygdomme |
| GB9220777D0 (en) * | 1992-10-02 | 1992-11-18 | Univ Leicester | Oligonucleotide probes |
| US5763198A (en) * | 1994-07-22 | 1998-06-09 | Sugen, Inc. | Screening assays for compounds |
| ATE423852T1 (de) | 1996-04-05 | 2009-03-15 | Antonio Giordano | Methoden zur diagnose und prognose von krebs |
| US5955269A (en) * | 1996-06-20 | 1999-09-21 | Rutgers, The State University Of New Jersey | Methods of screening foods for nutraceuticals |
| AU7987800A (en) * | 1999-09-29 | 2001-04-30 | Lifespan Biosciences, Inc. | Anti-aging nucleic acid and protein targets |
| WO2002039121A2 (en) * | 2000-11-03 | 2002-05-16 | Board Of Regents, The University Of Texas System | Methods for detecting the efficacy of anticancer treatments |
| EP1713938A2 (de) | 2004-02-09 | 2006-10-25 | Thomas Jefferson University | Diagnose und behandlung von krebserkrankungen mit oder nahe mit krebs in zusammenhang stehenden chromosomalen merkmalen lokalisierter microrna |
| US7012200B2 (en) * | 2004-02-13 | 2006-03-14 | Sonion Roskilde A/S | Integrated volume control and switch assembly |
| US20060019972A1 (en) * | 2004-04-27 | 2006-01-26 | California Institute Of Technology | Methods of treating cancer by inhibiting histone gene expression |
| CN101426930A (zh) * | 2004-05-25 | 2009-05-06 | 日立化成工业株式会社 | 检测癌症易感性的方法 |
| WO2006045053A2 (en) * | 2004-10-20 | 2006-04-27 | Hitachi Chemical Company, Ltd. | Method for tailoring administration of drugs by quantitation of mrna |
| WO2006086681A2 (en) * | 2005-02-09 | 2006-08-17 | Beth Israel Deaconess Medical Center, Inc. | Methods of inhibiting smooth muscle cell migration and proliferation |
| CN101166537B (zh) * | 2005-04-28 | 2013-01-23 | 日立化成研究中心公司 | 全血中基因的体外表达作为评定对饮食补充物个体差异的模型 |
| WO2007008252A1 (en) * | 2005-07-12 | 2007-01-18 | Temple University - Of The Commonwealth Systems Of Higher Education | Genetic and epigenetic alterations in the diagnosis and treatment of cancer |
| US8481505B2 (en) | 2005-09-12 | 2013-07-09 | The Ohio State University Research Foundation | Compositions and methods for the diagnosis and therapy of BCL2-associated cancers |
| WO2007081680A2 (en) | 2006-01-05 | 2007-07-19 | The Ohio State University Research Foundation | Microrna expression abnormalities in pancreatic endocrine and acinar tumors |
| AU2007205234B2 (en) | 2006-01-05 | 2012-07-12 | The Ohio State University Research Foundation | MicroRNA-based methods and compositions for the diagnosis, prognosis and treatment of lung cancer |
| EP2484782B1 (de) | 2006-01-05 | 2015-11-18 | The Ohio State University Research Foundation | Verfahren und Zusammensetzungen auf Mikro-RNA-Basis zur Diagnose und Behandlung von soliden Krebs |
| EP2522748A1 (de) | 2006-03-02 | 2012-11-14 | The Ohio State University | Mikro-RNA-Expressionsprofil im Zusammenhang mit Bauchspeicheldrüsenkrebs |
| ES2446362T3 (es) | 2006-03-20 | 2014-03-07 | The Ohio State University Research Foundation | Huellas de microARN durante megacariocipoyesis humana |
| WO2007133551A2 (en) * | 2006-05-08 | 2007-11-22 | Hitachi Chemical Co., Ltd. | Method for testing drug sensitivity in solid tumors by quantifying mrna expression in thinly-sliced tumor tissue |
| WO2007134142A2 (en) * | 2006-05-11 | 2007-11-22 | University College Dublin | Methods and compositions for identifying and using p21-regulated proteins |
| ES2425387T3 (es) | 2006-07-13 | 2013-10-15 | The Ohio State University Research Foundation | Mir-106a para diagnosticar adenocarcinoma de colon de pronóstico de supervivencia pobre |
| US8841436B2 (en) * | 2007-03-15 | 2014-09-23 | University Hospitals Cleveland Medical Center | Screening, diagnosing, treating and prognosis of pathophysiologic status by RNA regulation |
| US8465917B2 (en) | 2007-06-08 | 2013-06-18 | The Ohio State University Research Foundation | Methods for determining heptocellular carcinoma subtype and detecting hepatic cancer stem cells |
| WO2009012263A2 (en) * | 2007-07-18 | 2009-01-22 | The Trustees Of Columbia University In The City Of New York | Tissue-specific micrornas and compositions and uses thereof |
| EP2173911B1 (de) | 2007-07-31 | 2014-06-18 | The Ohio State University Research Foundation | Verfahren zur methylierungsreversion mittels abzielen auf dnmt3a und dnmt3b |
| EP2653561B1 (de) | 2007-08-03 | 2016-03-02 | The Ohio State University Research Foundation | Ultrakonservierte Bereiche zur Codierung von ncRNA |
| EP3028708A1 (de) | 2007-08-22 | 2016-06-08 | The Ohio State University Research Foundation | Verfahren und zusammensetzungen zur induzierung von epha7-deregulierung und erk-phosphorlylierung bei humaner akuter leukämie |
| EP3138926A3 (de) | 2007-09-06 | 2017-04-05 | The Ohio State University Research Foundation | Mirna-signaturen in menschlichem ovarialkarzinom |
| EP2212440A4 (de) | 2007-10-11 | 2011-04-06 | Univ Ohio State Res Found | Verfahren und zusammensetzungen zur diagnose und behandlung von adenokarzinomen der speiseröhre |
| EP2209919A4 (de) * | 2007-11-14 | 2011-04-13 | Hitachi Chemical Co Ltd | Fc-rezeptor-vermittelter-tumornekrosefaktor-superfamilie-mrna-expression in peripheren blutleukozyten |
| US20090215064A1 (en) * | 2008-02-27 | 2009-08-27 | Hitachi Chemical Co., Ltd. | Quantitative assessment of individual cancer susceptibility by measuring dna damage-induced mrna in whole blood |
| WO2010080985A1 (en) | 2009-01-08 | 2010-07-15 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for induced brown fat differentiation |
| EP2379720B1 (de) | 2009-01-20 | 2016-08-17 | Alona Zilberberg | Durch den promoter mir-21 angetriebene gezielte krebstherapie |
| WO2010105096A2 (en) | 2009-03-11 | 2010-09-16 | University Of Massachusetts | Modulation of human cytomegalovirus replication by micro-rna 132 (mir132), micro-rna 145 (mir145) and micro-rna 212 (mir212) |
| WO2010149666A1 (en) | 2009-06-22 | 2010-12-29 | Medexis S.A. | Methods for treating neoplasia |
| AU2010288810A1 (en) | 2009-08-31 | 2012-03-01 | University Of Bremen | MicroRNA-based methods and compositions for the diagnosis, prognosis and treatment of tumor involving chromosomal rearrangements |
| US20120238488A1 (en) | 2009-09-08 | 2012-09-20 | Konstantinos Alevizopoulos | Compounds and methods for treating neoplasia |
| WO2011109637A1 (en) | 2010-03-03 | 2011-09-09 | Koo Foundation Sun Yat-Sen Cancer Center | Methods for classifying and treating breast cancers |
| AU2011284606A1 (en) | 2010-07-30 | 2013-03-14 | Pharmacellion Ltd | Compounds and methods for treating neoplasia |
| CA2807244A1 (en) | 2010-08-27 | 2012-03-01 | University Of Zurich | A novel diagnostic and therapeutic target in inflammatory and/or cardiovascular diseases |
| EP2546358A1 (de) | 2011-07-15 | 2013-01-16 | Laboratorios Del. Dr. Esteve, S.A. | Verfahren und Reagenzien zur effizienten Steuerung des HIV-Fortschritts |
| CA2852066A1 (en) | 2011-10-14 | 2013-04-18 | The Ohio State University | Methods and materials related to ovarian cancer |
| AU2014233198B2 (en) | 2013-03-15 | 2019-06-27 | Sutter West Bay Hospitals | Falz for use as a target for therapies to treat cancer |
| WO2015006543A1 (en) | 2013-07-10 | 2015-01-15 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Method for predicting and detecting tumor metastasis in kidney cancer |
| JP6624704B2 (ja) | 2015-08-31 | 2019-12-25 | 日立化成株式会社 | 尿路上皮疾患の評価のための分子法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI76119C (fi) * | 1986-02-27 | 1988-09-09 | Orion Yhtymae Oy | Kvantitativ bestaemning av nukleinsyramolekyler och reagensfoerpackning som anvaends vid foerfarandet. |
| EP0290144A1 (de) * | 1987-05-05 | 1988-11-09 | City of Hope | Verfahren zum Nachweis von beginnender Widerstandsfähigkeit gegen therapeutische Agenzien bei Krebskranken |
-
1989
- 1989-05-04 DE DE68921918T patent/DE68921918T2/de not_active Expired - Fee Related
- 1989-05-04 EP EP89304494A patent/EP0341904B1/de not_active Expired - Lifetime
- 1989-05-04 AT AT89304494T patent/ATE120497T1/de active
- 1989-05-08 JP JP1113875A patent/JPH0636759B2/ja not_active Expired - Lifetime
-
1994
- 1994-08-10 US US08/288,151 patent/US5427916A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0341904A3 (de) | 1991-11-27 |
| DE68921918D1 (de) | 1995-05-04 |
| JPH0636759B2 (ja) | 1994-05-18 |
| EP0341904A2 (de) | 1989-11-15 |
| DE68921918T2 (de) | 1995-09-07 |
| US5427916A (en) | 1995-06-27 |
| JPH0213400A (ja) | 1990-01-17 |
| EP0341904B1 (de) | 1995-03-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE68921918D1 (de) | Verfahren zur Voraussage der Wirksamkeit einer antineoplastichen Behandlung bei einzelnen Patienten. | |
| ATE360989T1 (de) | Präzise wirksamkeitsbestimmungsmethode für wirkstoffe einschliesslich chemotherapeutika | |
| DE3782917D1 (de) | Verfahren zum herabsetzen des gehalts an rueckstaendigen aldehyden in implantierbaren bioprosthetischen geweben. | |
| DE3869490D1 (de) | Verfahren zur elektrochemischen behandlung von stoffen. | |
| PT87086A (pt) | Active specific immune suppression | |
| DE10199020I2 (de) | Galanthamin oder dessen Analoge zur Behandlung derAlzheimerschen Krankheit. | |
| DE3675632D1 (de) | Verfahren zur einbringung von sauerstoff in wasser und vorrichtung zur durchfuehrung des verfahrens. | |
| DE3880118D1 (de) | Verwendung eines mittels in form von mikrokapseln zur schabenbekaempfung. | |
| DE3874019D1 (de) | Verfahren zur konservierung von transplantierbaren, in vitro kultivierten epithelgeweben. | |
| ATE181422T1 (de) | Verfahren zur diagnose von praeklampsie | |
| DE3869230D1 (de) | Verfahren zur herstellung einer loesung hoher spezifischer volumenaktivitaet von einem protein mit gewebe-plasminogenaktivator (t-pa)-aktivitaet, loesung, enthaltend protein mit t-pa-aktivitaet und verwendung der loesung in der human- und veterinaermedizin. | |
| DE68912661D1 (de) | Verfahren und Vorrichtung für Zellkultur. | |
| DE69022778D1 (de) | Zellkultursubstrat, Bioreaktor mit Zellkultursubstrat und therapeutische Vorrichtung vom extrakorporalen Umlauftyp. | |
| EP0340783A3 (en) | Apparatus for culturing animal cells, method of culturing thereof and diagnostics of the culture | |
| NO882854L (no) | Korreksjon med dobbeltraadet rna av avvikende metabolske spor forbundet med ukontrollerte vekstsykluser for tumorceller og virus. | |
| ATA405377A (de) | Verfahren zur waermebehandlung von artikeln sowie vorrichtung zur durchfuehrung des verfahrens | |
| AT383491B (de) | Vorrichtung zum verabreichen von voll- oder sitz- baedern, insbesondere unter verwendung von peloid | |
| DE3879754D1 (de) | Hydrophiler zusatz zum zuechten von pilzen und verfahren zu seiner verwendung. | |
| DE3850652D1 (de) | Zellenzuchtverfahren und vorrichtung. | |
| NO884061D0 (no) | Fremgangsmaate for regulering av surhetsgraden i et elektrolytisk bad. | |
| DE3862788D1 (de) | Fluessige oxydationsmodifizierte ethylenische statistische copolymere, verfahren zur herstellung und deren verwendung. | |
| FR2492262B1 (fr) | Procede et dispositif de commande d'un appareil ou instrument notamment un stimulateur cardiaque implantable | |
| DE3884777D1 (de) | Verfahren zur Herstellung von Pregneno-Oxazolinen. | |
| DE3889232D1 (de) | Verfahren zum quantitativen Nachweis von Sauerstoff. | |
| DK0782452T3 (da) | Cellevækstregulator |