ATE120497T1 - Verfahren zur voraussage der wirksamkeit einer antineoplastichen behandlung bei einzelnen patienten. - Google Patents
Verfahren zur voraussage der wirksamkeit einer antineoplastichen behandlung bei einzelnen patienten.Info
- Publication number
- ATE120497T1 ATE120497T1 AT89304494T AT89304494T ATE120497T1 AT E120497 T1 ATE120497 T1 AT E120497T1 AT 89304494 T AT89304494 T AT 89304494T AT 89304494 T AT89304494 T AT 89304494T AT E120497 T1 ATE120497 T1 AT E120497T1
- Authority
- AT
- Austria
- Prior art keywords
- effectiveness
- individual patients
- expression
- predicting
- antineoplastic treatment
- Prior art date
Links
- 230000000118 anti-neoplastic effect Effects 0.000 title 1
- 229940034982 antineoplastic agent Drugs 0.000 abstract 2
- 239000002246 antineoplastic agent Substances 0.000 abstract 2
- 210000005170 neoplastic cell Anatomy 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 230000001105 regulatory effect Effects 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000011534 incubation Methods 0.000 abstract 1
- 230000000977 initiatory effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function
- Y10S436/813—Cancer
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19144988A | 1988-05-09 | 1988-05-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE120497T1 true ATE120497T1 (de) | 1995-04-15 |
Family
ID=22705545
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89304494T ATE120497T1 (de) | 1988-05-09 | 1989-05-04 | Verfahren zur voraussage der wirksamkeit einer antineoplastichen behandlung bei einzelnen patienten. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5427916A (de) |
| EP (1) | EP0341904B1 (de) |
| JP (1) | JPH0636759B2 (de) |
| AT (1) | ATE120497T1 (de) |
| DE (1) | DE68921918T2 (de) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI931268A7 (fi) * | 1990-09-24 | 1993-04-21 | Massachusetts Gen Hospital | Seulontamenetelmiä |
| ATE143700T1 (de) * | 1991-09-23 | 1996-10-15 | Pfizer | Verfahren für die detektion von spezifische mrns und dns in zellen |
| US5411860A (en) * | 1992-04-07 | 1995-05-02 | The Johns Hopkins University | Amplification of human MDM2 gene in human tumors |
| US5916772A (en) * | 1992-06-16 | 1999-06-29 | Whittier Institute For Diabetes And Endocrinology | Recombinant production of saporin-containing proteins |
| WO1994000599A2 (en) * | 1992-06-18 | 1994-01-06 | Whittier Institute For Diabetes And Endocrinology | Process for detection of neoplastic disease |
| GB9220777D0 (en) * | 1992-10-02 | 1992-11-18 | Univ Leicester | Oligonucleotide probes |
| US5763198A (en) * | 1994-07-22 | 1998-06-09 | Sugen, Inc. | Screening assays for compounds |
| EP2014772A3 (de) | 1996-04-05 | 2009-05-27 | Antonio Giordano | Verfahren zur Diagnose und Prognose von Krebs |
| US5955269A (en) * | 1996-06-20 | 1999-09-21 | Rutgers, The State University Of New Jersey | Methods of screening foods for nutraceuticals |
| AU7987800A (en) * | 1999-09-29 | 2001-04-30 | Lifespan Biosciences, Inc. | Anti-aging nucleic acid and protein targets |
| AU2002236572A1 (en) * | 2000-11-03 | 2002-05-21 | Board Of Regents, The University Of Texas System | Methods for detecting the efficacy of anticancer treatments |
| CA2554818A1 (en) | 2004-02-09 | 2005-08-25 | Thomas Jefferson University | Diagnosis and treatment of cancers with microrna located in or near cancer-associated chromosomal features |
| US7012200B2 (en) * | 2004-02-13 | 2006-03-14 | Sonion Roskilde A/S | Integrated volume control and switch assembly |
| US20060019972A1 (en) * | 2004-04-27 | 2006-01-26 | California Institute Of Technology | Methods of treating cancer by inhibiting histone gene expression |
| EP1776471B9 (de) * | 2004-05-25 | 2013-12-18 | Hitachi Chemical Company, Ltd. | Verfahren zur messung der anfälligkeit für krebs |
| CN101044249B (zh) * | 2004-10-20 | 2012-09-05 | 日立化成工业株式会社 | 通过定量mRNA定制给药的方法 |
| WO2006086681A2 (en) * | 2005-02-09 | 2006-08-17 | Beth Israel Deaconess Medical Center, Inc. | Methods of inhibiting smooth muscle cell migration and proliferation |
| KR100983450B1 (ko) * | 2005-04-28 | 2010-09-20 | 히다치 가세고교 가부시끼가이샤 | 식품보충제에 대한 개별적 다양성 평가의 모델로서 전혈내의 생체 외 유전자 발현 |
| JP2009501024A (ja) * | 2005-07-12 | 2009-01-15 | テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション | 癌の診断及び治療における遺伝的及びエピジェネティックな変化 |
| CA2621441C (en) | 2005-09-12 | 2014-05-20 | The Ohio State University Research Foundation | Compositions and methods for the diagnosis and therapy of bcl2-associated cancers |
| CN101384273B (zh) | 2006-01-05 | 2013-07-10 | 俄亥俄州立大学研究基金会 | 胰腺内分泌和腺泡肿瘤中的微小rna表达异常 |
| EP2484782B1 (de) | 2006-01-05 | 2015-11-18 | The Ohio State University Research Foundation | Verfahren und Zusammensetzungen auf Mikro-RNA-Basis zur Diagnose und Behandlung von soliden Krebs |
| EP2502630B1 (de) | 2006-01-05 | 2015-03-11 | The Ohio State University Research Foundation | Verfahren und Zusammensetzungen auf Mikro-RNA-Basis zur Diagnose, Prognose und Behandlung von Lungenkrebs |
| ES2448491T3 (es) | 2006-03-02 | 2014-03-14 | The Ohio State University Research Foundation | Perfil de expresión de microARN asociado con cáncer de páncreas |
| EP2369013A1 (de) | 2006-03-20 | 2011-09-28 | The Ohio State University Research Foundation | Mikro-RNA-Fingerabdrücke während humaner Megakaryozytopoiese |
| JP2009536524A (ja) * | 2006-05-08 | 2009-10-15 | 日立化成工業株式会社 | 薄切りにした腫瘍組織におけるｍＲＮＡ発現を定量することによって固形腫瘍の薬剤感受性を検査する方法 |
| WO2007134142A2 (en) * | 2006-05-11 | 2007-11-22 | University College Dublin | Methods and compositions for identifying and using p21-regulated proteins |
| EP2455493B1 (de) | 2006-07-13 | 2014-01-08 | The Ohio State University Research Foundation | Verfahren und Zusammensetzungen auf Mikro-RNA-Basis zur Diagnose und Behandlung von Krankheiten im Zusammenhang mit dem Dickdarm |
| WO2008115387A2 (en) * | 2007-03-15 | 2008-09-25 | University Hospitals Of Cleveland | Screening, diagnosing, treating and prognosis of pathophysiologic states by rna regulation |
| CN101711287B (zh) | 2007-06-08 | 2016-04-27 | 由卫生与公众服务部代表的美利坚合众国政府 | 确定肝细胞癌亚型和检测肝癌干细胞的方法 |
| WO2009012263A2 (en) * | 2007-07-18 | 2009-01-22 | The Trustees Of Columbia University In The City Of New York | Tissue-specific micrornas and compositions and uses thereof |
| CN101809169B (zh) | 2007-07-31 | 2013-07-17 | 俄亥俄州立大学研究基金会 | 通过靶向dnmt3a和dnmt3b恢复甲基化的方法 |
| EP2173908B1 (de) | 2007-08-03 | 2016-01-06 | The Ohio State University Research Foundation | Ultrakonservierte bereiche zur kodierung von ncrnas |
| CA2926831A1 (en) | 2007-08-22 | 2009-02-26 | The Ohio State University Research Foundation | Methods and compositions for inducing deregulation of epha7 and erk phosphorylation in human acute leukemias |
| CA2698771A1 (en) | 2007-09-06 | 2009-03-12 | The Ohio State University Research Foundation | Microrna signatures in human ovarian cancer |
| CN103937876B (zh) | 2007-10-11 | 2016-08-17 | 俄亥俄州立大学研究基金会 | 用于诊断和治疗食管腺癌的方法和组合物 |
| CN101855367A (zh) * | 2007-11-14 | 2010-10-06 | 日立化成工业株式会社 | 外周血白细胞中FC受体介导的肿瘤坏死因子超家族mRNA表达 |
| US20090215064A1 (en) * | 2008-02-27 | 2009-08-27 | Hitachi Chemical Co., Ltd. | Quantitative assessment of individual cancer susceptibility by measuring dna damage-induced mrna in whole blood |
| WO2010080985A1 (en) | 2009-01-08 | 2010-07-15 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for induced brown fat differentiation |
| JP2012515532A (ja) | 2009-01-20 | 2012-07-12 | ラモット アット テル アビブ ユニバーシティ， リミテッド | Ｍｉｒ−２１プロモーター駆動性標的がん治療 |
| WO2010105096A2 (en) | 2009-03-11 | 2010-09-16 | University Of Massachusetts | Modulation of human cytomegalovirus replication by micro-rna 132 (mir132), micro-rna 145 (mir145) and micro-rna 212 (mir212) |
| WO2010149666A1 (en) | 2009-06-22 | 2010-12-29 | Medexis S.A. | Methods for treating neoplasia |
| US8828656B2 (en) | 2009-08-31 | 2014-09-09 | University Of Bremen | Microrna-based methods and compositions for the diagnosis, prognosis and treatment of tumor involving chromosomal rearrangements |
| US20120238488A1 (en) | 2009-09-08 | 2012-09-20 | Konstantinos Alevizopoulos | Compounds and methods for treating neoplasia |
| US20110217297A1 (en) | 2010-03-03 | 2011-09-08 | Koo Foundation Sun Yat-Sen Cancer Center | Methods for classifying and treating breast cancers |
| US20130303500A1 (en) | 2010-07-30 | 2013-11-14 | Medexis S.A. | Compounds and methods for treating neoplasia |
| EP2609211A1 (de) | 2010-08-27 | 2013-07-03 | University of Zurich | Neuartiges diagnostisches und therapeutisches target in entzündlichen und/oder kardiovaskulären erkrankungen |
| EP2546358A1 (de) | 2011-07-15 | 2013-01-16 | Laboratorios Del. Dr. Esteve, S.A. | Verfahren und Reagenzien zur effizienten Steuerung des HIV-Fortschritts |
| EP2766500A4 (de) | 2011-10-14 | 2015-10-14 | Univ Ohio State | Verfahren und materialien in verbindung mit eierstockkrebs |
| CA2907184C (en) | 2013-03-15 | 2022-12-06 | Sutter West Bay Hospitals | Falz for use as a target for therapies to treat cancer |
| WO2015006543A1 (en) | 2013-07-10 | 2015-01-15 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Method for predicting and detecting tumor metastasis in kidney cancer |
| JP6624704B2 (ja) | 2015-08-31 | 2019-12-25 | 日立化成株式会社 | 尿路上皮疾患の評価のための分子法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI76119C (fi) * | 1986-02-27 | 1988-09-09 | Orion Yhtymae Oy | Kvantitativ bestaemning av nukleinsyramolekyler och reagensfoerpackning som anvaends vid foerfarandet. |
| EP0290144A1 (de) * | 1987-05-05 | 1988-11-09 | City of Hope | Verfahren zum Nachweis von beginnender Widerstandsfähigkeit gegen therapeutische Agenzien bei Krebskranken |
-
1989
- 1989-05-04 AT AT89304494T patent/ATE120497T1/de active
- 1989-05-04 DE DE68921918T patent/DE68921918T2/de not_active Expired - Fee Related
- 1989-05-04 EP EP89304494A patent/EP0341904B1/de not_active Expired - Lifetime
- 1989-05-08 JP JP1113875A patent/JPH0636759B2/ja not_active Expired - Lifetime
-
1994
- 1994-08-10 US US08/288,151 patent/US5427916A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0341904A2 (de) | 1989-11-15 |
| JPH0213400A (ja) | 1990-01-17 |
| US5427916A (en) | 1995-06-27 |
| JPH0636759B2 (ja) | 1994-05-18 |
| EP0341904A3 (de) | 1991-11-27 |
| DE68921918T2 (de) | 1995-09-07 |
| EP0341904B1 (de) | 1995-03-29 |
| DE68921918D1 (de) | 1995-05-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE68921918D1 (de) | Verfahren zur Voraussage der Wirksamkeit einer antineoplastichen Behandlung bei einzelnen Patienten. | |
| ATE360989T1 (de) | Präzise wirksamkeitsbestimmungsmethode für wirkstoffe einschliesslich chemotherapeutika | |
| DE3782917D1 (de) | Verfahren zum herabsetzen des gehalts an rueckstaendigen aldehyden in implantierbaren bioprosthetischen geweben. | |
| DE3869490D1 (de) | Verfahren zur elektrochemischen behandlung von stoffen. | |
| PT87086A (pt) | Active specific immune suppression | |
| DE10199020I2 (de) | Galanthamin oder dessen Analoge zur Behandlung derAlzheimerschen Krankheit. | |
| DE3880118D1 (de) | Verwendung eines mittels in form von mikrokapseln zur schabenbekaempfung. | |
| DE3675632D1 (de) | Verfahren zur einbringung von sauerstoff in wasser und vorrichtung zur durchfuehrung des verfahrens. | |
| DE3874019D1 (de) | Verfahren zur konservierung von transplantierbaren, in vitro kultivierten epithelgeweben. | |
| ATE181422T1 (de) | Verfahren zur diagnose von praeklampsie | |
| DE3869230D1 (de) | Verfahren zur herstellung einer loesung hoher spezifischer volumenaktivitaet von einem protein mit gewebe-plasminogenaktivator (t-pa)-aktivitaet, loesung, enthaltend protein mit t-pa-aktivitaet und verwendung der loesung in der human- und veterinaermedizin. | |
| DE68912661D1 (de) | Verfahren und Vorrichtung für Zellkultur. | |
| DE69022778D1 (de) | Zellkultursubstrat, Bioreaktor mit Zellkultursubstrat und therapeutische Vorrichtung vom extrakorporalen Umlauftyp. | |
| EP0340783A3 (en) | Apparatus for culturing animal cells, method of culturing thereof and diagnostics of the culture | |
| NO882854L (no) | Korreksjon med dobbeltraadet rna av avvikende metabolske spor forbundet med ukontrollerte vekstsykluser for tumorceller og virus. | |
| ATA405377A (de) | Verfahren zur waermebehandlung von artikeln sowie vorrichtung zur durchfuehrung des verfahrens | |
| AT383491B (de) | Vorrichtung zum verabreichen von voll- oder sitz- baedern, insbesondere unter verwendung von peloid | |
| DE3879754D1 (de) | Hydrophiler zusatz zum zuechten von pilzen und verfahren zu seiner verwendung. | |
| DE3850652D1 (de) | Zellenzuchtverfahren und vorrichtung. | |
| NO884061D0 (no) | Fremgangsmaate for regulering av surhetsgraden i et elektrolytisk bad. | |
| DE3862788D1 (de) | Fluessige oxydationsmodifizierte ethylenische statistische copolymere, verfahren zur herstellung und deren verwendung. | |
| FR2492262B1 (fr) | Procede et dispositif de commande d'un appareil ou instrument notamment un stimulateur cardiaque implantable | |
| DE3884777D1 (de) | Verfahren zur Herstellung von Pregneno-Oxazolinen. | |
| DE3889232D1 (de) | Verfahren zum quantitativen Nachweis von Sauerstoff. | |
| DK0782452T3 (da) | Cellevækstregulator |