ATE120497T1 - Verfahren zur voraussage der wirksamkeit einer antineoplastichen behandlung bei einzelnen patienten. - Google Patents
Verfahren zur voraussage der wirksamkeit einer antineoplastichen behandlung bei einzelnen patienten.Info
- Publication number
- ATE120497T1 ATE120497T1 AT89304494T AT89304494T ATE120497T1 AT E120497 T1 ATE120497 T1 AT E120497T1 AT 89304494 T AT89304494 T AT 89304494T AT 89304494 T AT89304494 T AT 89304494T AT E120497 T1 ATE120497 T1 AT E120497T1
- Authority
- AT
- Austria
- Prior art keywords
- effectiveness
- individual patients
- expression
- predicting
- antineoplastic treatment
- Prior art date
Links
- 230000000118 anti-neoplastic effect Effects 0.000 title 1
- 229940034982 antineoplastic agent Drugs 0.000 abstract 2
- 239000002246 antineoplastic agent Substances 0.000 abstract 2
- 210000005170 neoplastic cell Anatomy 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 230000001105 regulatory effect Effects 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000011534 incubation Methods 0.000 abstract 1
- 230000000977 initiatory effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function
- Y10S436/813—Cancer
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19144988A | 1988-05-09 | 1988-05-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE120497T1 true ATE120497T1 (de) | 1995-04-15 |
Family
ID=22705545
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89304494T ATE120497T1 (de) | 1988-05-09 | 1989-05-04 | Verfahren zur voraussage der wirksamkeit einer antineoplastichen behandlung bei einzelnen patienten. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5427916A (de) |
| EP (1) | EP0341904B1 (de) |
| JP (1) | JPH0636759B2 (de) |
| AT (1) | ATE120497T1 (de) |
| DE (1) | DE68921918T2 (de) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR930703462A (ko) * | 1990-09-24 | 1993-11-30 | 로저 브렌트 | 검색 분석 방법 |
| ES2092056T3 (es) * | 1991-09-23 | 1996-11-16 | Pfizer | Procedimiento para detectar arnm y adn especificos en celulas. |
| US5411860A (en) * | 1992-04-07 | 1995-05-02 | The Johns Hopkins University | Amplification of human MDM2 gene in human tumors |
| US5916772A (en) * | 1992-06-16 | 1999-06-29 | Whittier Institute For Diabetes And Endocrinology | Recombinant production of saporin-containing proteins |
| EP0646182B1 (de) * | 1992-06-18 | 1996-08-28 | The Whittier Institute For Diabetes And Endocrinology | Verfahren zur detektion neoplastischer erkrankungen |
| GB9220777D0 (en) * | 1992-10-02 | 1992-11-18 | Univ Leicester | Oligonucleotide probes |
| US5763198A (en) * | 1994-07-22 | 1998-06-09 | Sugen, Inc. | Screening assays for compounds |
| CA2250854C (en) | 1996-04-05 | 2011-06-21 | Thomas Jefferson University | Methods for the diagnosis and prognosis of cancer |
| US5955269A (en) * | 1996-06-20 | 1999-09-21 | Rutgers, The State University Of New Jersey | Methods of screening foods for nutraceuticals |
| WO2001023615A1 (en) * | 1999-09-29 | 2001-04-05 | Lifespan Biosciences, Inc. | Anti-aging nucleic acid and protein targets |
| JP2004529315A (ja) * | 2000-11-03 | 2004-09-24 | ボード オブ リージェンツ， ザ ユニバーシティ オブ テキサス システム | 抗癌処置の効力を検出するための方法 |
| WO2005078139A2 (en) | 2004-02-09 | 2005-08-25 | Thomas Jefferson University | DIAGNOSIS AND TREATMENT OF CANCERS WITH MicroRNA LOCATED IN OR NEAR CANCER-ASSOCIATED CHROMOSOMAL FEATURES |
| US7012200B2 (en) * | 2004-02-13 | 2006-03-14 | Sonion Roskilde A/S | Integrated volume control and switch assembly |
| WO2005112924A2 (en) * | 2004-04-27 | 2005-12-01 | California Institute Of Technology | Methods of treating cancer by inhibiting histone gene expression |
| EP1776471B9 (de) * | 2004-05-25 | 2013-12-18 | Hitachi Chemical Company, Ltd. | Verfahren zur messung der anfälligkeit für krebs |
| JP4772055B2 (ja) * | 2004-10-20 | 2011-09-14 | 日立化成工業株式会社 | ｍＲＮＡの定量により薬剤の投与を選定する方法 |
| WO2006086681A2 (en) * | 2005-02-09 | 2006-08-17 | Beth Israel Deaconess Medical Center, Inc. | Methods of inhibiting smooth muscle cell migration and proliferation |
| JP4945554B2 (ja) * | 2005-04-28 | 2012-06-06 | ヒタチ ケミカル リサーチ センター インコーポレイテッド | 食物サプリメントに対する個体変動評価のモデルとしての全血におけるｅｘｖｉｖｏ遺伝子発現 |
| US20090270479A1 (en) * | 2005-07-12 | 2009-10-29 | Antonio Giordano | Genetic and Epigenetic Alterations In the Diagnosis and Treatment of Cancer |
| EP1937280B1 (de) | 2005-09-12 | 2014-08-27 | The Ohio State University Research Foundation | Zusammensetzungen zur Therapie von Bcl2-assoziierten Tumoren |
| EP2487261B1 (de) | 2006-01-05 | 2015-07-01 | The Ohio State University Research Foundation | Verfahren und Zusammensetzungen auf Mikro-RNA-Basis zur Diagnose und Behandlung von festen Krebsen |
| ES2429404T3 (es) | 2006-01-05 | 2013-11-14 | The Ohio State University Research Foundation | Procedimientos basados en los microARN para el diagnóstico y el pronóstico del cáncer de pulmón |
| JP5490413B2 (ja) | 2006-01-05 | 2014-05-14 | ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション | 膵内分泌腫瘍及び膵腺房腫瘍におけるマイクロｒｎａ発現異常 |
| WO2007103808A2 (en) | 2006-03-02 | 2007-09-13 | The Ohio State University | Microrna expression profile associated with pancreatic cancer |
| CA2646051A1 (en) | 2006-03-20 | 2007-09-27 | Carlo M. Croce | Microrna fingerprints during human megakaryocytopoiesis |
| WO2009070442A2 (en) * | 2007-11-14 | 2009-06-04 | Hitachi Chemical Co. Ltd. | Fc receptor-mediated tumor necrosis factor superfamily mrna expression in peripheral blood leukocytes |
| EP2015783A4 (de) * | 2006-05-08 | 2010-07-21 | Hitachi Chemical Co Ltd | Verfahren zur überprüfung der wirkstoffempfindlichkeit fester tumore durch quantifizierung der mrna-expression in dünn geschnittenem tumorgewebe |
| WO2007134142A2 (en) * | 2006-05-11 | 2007-11-22 | University College Dublin | Methods and compositions for identifying and using p21-regulated proteins |
| WO2008008430A2 (en) | 2006-07-13 | 2008-01-17 | The Ohio State University Research Foundation | Micro-rna-based methods and compositions for the diagnosis and treatment of colon cancer-related diseases |
| WO2008115387A2 (en) * | 2007-03-15 | 2008-09-25 | University Hospitals Of Cleveland | Screening, diagnosing, treating and prognosis of pathophysiologic states by rna regulation |
| ES2527648T3 (es) | 2007-06-08 | 2015-01-28 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Métodos para determinar el subtipo de carcinoma hepatocelular |
| WO2009012263A2 (en) * | 2007-07-18 | 2009-01-22 | The Trustees Of Columbia University In The City Of New York | Tissue-specific micrornas and compositions and uses thereof |
| CA2695184A1 (en) | 2007-07-31 | 2009-02-05 | The Ohio State University Research Foundation | Methods for reverting methylation by targeting dnmt3a and dnmt3b |
| ES2570359T3 (es) | 2007-08-03 | 2016-05-18 | Univ Ohio State Res Found | Regiones ultraconservadas que codifican ARNnc |
| EP3028708A1 (de) | 2007-08-22 | 2016-06-08 | The Ohio State University Research Foundation | Verfahren und zusammensetzungen zur induzierung von epha7-deregulierung und erk-phosphorlylierung bei humaner akuter leukämie |
| AU2008296022B2 (en) | 2007-09-06 | 2014-01-23 | The Ohio State University Research Foundation | MicroRNA signatures in human ovarian cancer |
| CA2702241A1 (en) | 2007-10-11 | 2009-04-16 | The Ohio State University Research Foundation | Methods and compositions for the diagnosis and treatment of esophageal adenocarcinomas |
| US20090215064A1 (en) * | 2008-02-27 | 2009-08-27 | Hitachi Chemical Co., Ltd. | Quantitative assessment of individual cancer susceptibility by measuring dna damage-induced mrna in whole blood |
| US9181315B2 (en) | 2009-01-08 | 2015-11-10 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for induced brown fat differentiation |
| WO2010084488A1 (en) | 2009-01-20 | 2010-07-29 | Ramot At Tel-Aviv University Ltd. | Mir-21 promoter driven targeted cancer therapy |
| WO2010105096A2 (en) | 2009-03-11 | 2010-09-16 | University Of Massachusetts | Modulation of human cytomegalovirus replication by micro-rna 132 (mir132), micro-rna 145 (mir145) and micro-rna 212 (mir212) |
| WO2010149666A1 (en) | 2009-06-22 | 2010-12-29 | Medexis S.A. | Methods for treating neoplasia |
| WO2011023413A1 (en) | 2009-08-31 | 2011-03-03 | Alcedo Biotech Gmbh | Microrna-based methods and compositions for reprogramming cells |
| US20120238488A1 (en) | 2009-09-08 | 2012-09-20 | Konstantinos Alevizopoulos | Compounds and methods for treating neoplasia |
| US20110217297A1 (en) | 2010-03-03 | 2011-09-08 | Koo Foundation Sun Yat-Sen Cancer Center | Methods for classifying and treating breast cancers |
| EP2598513A1 (de) | 2010-07-30 | 2013-06-05 | Medexis S.A. | Verbindungen und verfahren zur behandlung von neoplasien |
| WO2012025633A1 (en) | 2010-08-27 | 2012-03-01 | University Of Zurich | A novel diagnostic and therapeutic target in inflammatory and/or cardiovascular diseases |
| EP2546358A1 (de) | 2011-07-15 | 2013-01-16 | Laboratorios Del. Dr. Esteve, S.A. | Verfahren und Reagenzien zur effizienten Steuerung des HIV-Fortschritts |
| CN104364390B (zh) | 2011-10-14 | 2016-08-24 | 俄亥俄州立大学 | 与卵巢癌相关的方法和材料 |
| CN105189786B (zh) | 2013-03-15 | 2018-04-03 | 萨特西湾医院 | 用作治疗癌症的疗法的靶标的falz |
| WO2015006543A1 (en) | 2013-07-10 | 2015-01-15 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Method for predicting and detecting tumor metastasis in kidney cancer |
| US11028443B2 (en) | 2015-08-31 | 2021-06-08 | Showa Denko Materials Co., Ltd. | Molecular methods for assessing urothelial disease |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI76119C (fi) * | 1986-02-27 | 1988-09-09 | Orion Yhtymae Oy | Kvantitativ bestaemning av nukleinsyramolekyler och reagensfoerpackning som anvaends vid foerfarandet. |
| NO881560L (no) * | 1987-05-05 | 1988-11-07 | Hope City | Fremgangsmaate for detektering av begynnende resistens motterapeutiske midler i kreftpasienter. |
-
1989
- 1989-05-04 EP EP89304494A patent/EP0341904B1/de not_active Expired - Lifetime
- 1989-05-04 AT AT89304494T patent/ATE120497T1/de active
- 1989-05-04 DE DE68921918T patent/DE68921918T2/de not_active Expired - Fee Related
- 1989-05-08 JP JP1113875A patent/JPH0636759B2/ja not_active Expired - Lifetime
-
1994
- 1994-08-10 US US08/288,151 patent/US5427916A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0341904B1 (de) | 1995-03-29 |
| JPH0213400A (ja) | 1990-01-17 |
| JPH0636759B2 (ja) | 1994-05-18 |
| EP0341904A3 (de) | 1991-11-27 |
| DE68921918D1 (de) | 1995-05-04 |
| DE68921918T2 (de) | 1995-09-07 |
| EP0341904A2 (de) | 1989-11-15 |
| US5427916A (en) | 1995-06-27 |
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