ATE12105T1 - Herzmuskelschonende pyrrolderivate mit antiarythmischer und anti-plaettchenklumpungswirkung, verfahren zu ihrer herstellung und sie enthaltende arzneimittel. - Google Patents

Herzmuskelschonende pyrrolderivate mit antiarythmischer und anti-plaettchenklumpungswirkung, verfahren zu ihrer herstellung und sie enthaltende arzneimittel.

Info

Publication number: ATE12105T1
Authority: AT; Austria
Prior art keywords: radical; see diagramm; formula see; atoms; carbon
Prior art date: 1980-12-18

Application number

AT80401813T

Other languages

English (en)

Inventor

Claude Bernhart

Jean-Pierre Gagnol

Patrick Gautier

Original Assignee

Sanofi Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-12-18

Filing date

1980-12-18

Publication date

1985-03-15

1980-12-18 Application filed by Sanofi Sa filed Critical Sanofi Sa

1985-03-15 Application granted granted Critical

1985-03-15 Publication of ATE12105T1 publication Critical patent/ATE12105T1/de

Links

238000000034 method Methods 0.000 title abstract 3
KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical class C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 title 1
239000003814 drug Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
125000004429 atom Chemical group 0.000 abstract 9
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 5
229910052799 carbon Inorganic materials 0.000 abstract 5
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
125000003386 piperidinyl group Chemical group 0.000 abstract 4
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 2
150000001408 amides Chemical class 0.000 abstract 2
229910052500 inorganic mineral Inorganic materials 0.000 abstract 2
239000011707 mineral Substances 0.000 abstract 2
150000007522 mineralic acids Chemical class 0.000 abstract 2
125000002757 morpholinyl group Chemical group 0.000 abstract 2
150000007524 organic acids Chemical class 0.000 abstract 2
235000005985 organic acids Nutrition 0.000 abstract 2
150000003233 pyrroles Chemical class 0.000 abstract 2
125000000719 pyrrolidinyl group Chemical group 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
229910021529 ammonia Inorganic materials 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
238000010438 heat treatment Methods 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
150000004702 methyl esters Chemical class 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
238000007127 saponification reaction Methods 0.000 abstract 1
YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
- C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pyrrole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

AT80401813T 1980-12-18 1980-12-18 Herzmuskelschonende pyrrolderivate mit antiarythmischer und anti-plaettchenklumpungswirkung, verfahren zu ihrer herstellung und sie enthaltende arzneimittel. ATE12105T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP80401813A EP0054593B1 (de)	1980-12-18	1980-12-18	Herzmuskelschonende Pyrrolderivate mit anti-arythmischer und Anti-Plättchenklumpungswirkung, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel

Publications (1)

Publication Number	Publication Date
ATE12105T1 true ATE12105T1 (de)	1985-03-15

Family

ID=8187412

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT80401813T ATE12105T1 (de)	1980-12-18	1980-12-18	Herzmuskelschonende pyrrolderivate mit antiarythmischer und anti-plaettchenklumpungswirkung, verfahren zu ihrer herstellung und sie enthaltende arzneimittel.

Country Status (4)

Country	Link
EP (1)	EP0054593B1 (de)
AT (1)	ATE12105T1 (de)
AU (1)	AU541251B2 (de)
DE (1)	DE3070296D1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2036192A1 (en) *	1990-02-13	1991-08-14	Nicholas Meanwell	Heterocyclic carboxylic acids and esters

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1013906A (en) *	1961-08-18	1965-12-22	Pfizer & Co C	Cyclization process and product
DE2647368A1 (de) *	1975-10-23	1977-05-05	Ciba Geigy Ag	Alpha-(1-pyrrolyl)-carbonsaeure-3- phenoxy-benzylester, verfahren zu ihrer herstellung und ihre verwendung

1980
- 1980-12-18 EP EP80401813A patent/EP0054593B1/de not_active Expired
- 1980-12-18 AT AT80401813T patent/ATE12105T1/de not_active IP Right Cessation
- 1980-12-18 DE DE8080401813T patent/DE3070296D1/de not_active Expired
1981
- 1981-01-30 AU AU66775/81A patent/AU541251B2/en not_active Ceased

Also Published As

Publication number	Publication date
EP0054593B1 (de)	1985-03-13
DE3070296D1 (en)	1985-04-18
AU541251B2 (en)	1985-01-03
EP0054593A1 (de)	1982-06-30
AU6677581A (en)	1982-08-05

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Legal Events

Date	Code	Title	Description
1985-07-15	UEP	Publication of translation of european patent specification
1988-10-15	REN	Ceased due to non-payment of the annual fee