ATE121261T1 - Auf alpha-tocopherol basierte bläschen. - Google Patents

Auf alpha-tocopherol basierte bläschen.

Info

Publication number
ATE121261T1
ATE121261T1 AT86906559T AT86906559T ATE121261T1 AT E121261 T1 ATE121261 T1 AT E121261T1 AT 86906559 T AT86906559 T AT 86906559T AT 86906559 T AT86906559 T AT 86906559T AT E121261 T1 ATE121261 T1 AT E121261T1
Authority
AT
Austria
Prior art keywords
alpha
based bubbles
tocopherol based
tocopherol
optionally
Prior art date
Application number
AT86906559T
Other languages
English (en)
Inventor
Andrew S Janoff
Lois E Bolcsak
Alan L Weiner
Paul A Tremblay
Michael V W Bergamini
Robert L Suddith
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27120576&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE121261(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Application granted granted Critical
Publication of ATE121261T1 publication Critical patent/ATE121261T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277Preparation processes; Proliposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/829Liposomes, e.g. encapsulation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Ophthalmology & Optometry (AREA)
  • Virology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT86906559T 1985-10-15 1986-10-06 Auf alpha-tocopherol basierte bläschen. ATE121261T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78674085A 1985-10-15 1985-10-15
US06/911,138 US4861580A (en) 1985-10-15 1986-09-24 Composition using salt form of organic acid derivative of alpha-tocopheral

Publications (1)

Publication Number Publication Date
ATE121261T1 true ATE121261T1 (de) 1995-05-15

Family

ID=27120576

Family Applications (2)

Application Number Title Priority Date Filing Date
AT86906559T ATE121261T1 (de) 1985-10-15 1986-10-06 Auf alpha-tocopherol basierte bläschen.
AT91115181T ATE141156T1 (de) 1985-10-15 1986-10-06 Extrusionsverfahren für liposome

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT91115181T ATE141156T1 (de) 1985-10-15 1986-10-06 Extrusionsverfahren für liposome

Country Status (9)

Country Link
US (1) US4861580A (de)
EP (2) EP0243446B1 (de)
JP (1) JP2848583B2 (de)
AT (2) ATE121261T1 (de)
AU (1) AU6543786A (de)
CA (1) CA1315678C (de)
DE (2) DE3650556T2 (de)
IL (1) IL80267A0 (de)
WO (1) WO1987002219A1 (de)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9203291A (es) * 1985-06-26 1992-08-01 Liposome Co Inc Metodo para acoplamiento de liposomas.
US5059421A (en) * 1985-07-26 1991-10-22 The Liposome Company, Inc. Preparation of targeted liposome systems of a defined size distribution
US5041278A (en) * 1985-10-15 1991-08-20 The Liposome Company, Inc. Alpha tocopherol-based vesicles
US6759057B1 (en) 1986-06-12 2004-07-06 The Liposome Company, Inc. Methods and compositions using liposome-encapsulated non-steroidal anti-inflammatory drugs
US5204112A (en) * 1986-06-16 1993-04-20 The Liposome Company, Inc. Induction of asymmetry in vesicles
US5252263A (en) * 1986-06-16 1993-10-12 The Liposome Company, Inc. Induction of asymmetry in vesicles
US6406713B1 (en) 1987-03-05 2002-06-18 The Liposome Company, Inc. Methods of preparing low-toxicity drug-lipid complexes
US5616334A (en) * 1987-03-05 1997-04-01 The Liposome Company, Inc. Low toxicity drug-lipid systems
MX9203808A (es) * 1987-03-05 1992-07-01 Liposome Co Inc Formulaciones de alto contenido de medicamento: lipido, de agentes liposomicos-antineoplasticos.
US5154930A (en) * 1987-03-05 1992-10-13 The Liposome Company, Inc. Pharmacological agent-lipid solution preparation
JPH02502978A (ja) * 1987-04-16 1990-09-20 ザ リポソーム カンパニー,インコーポレイテッド リポソームの連続的サイズ減少方法及び装置
KR920003601B1 (ko) * 1987-09-03 1992-05-04 유니버시티 어브 죠지아 리서취 화운데이션 인코포레이티드 점안 싸이클로스포린(cyclosporin)의 조성물
MX9203804A (es) * 1987-10-19 1992-07-01 Liposome Co Inc Sistemas farmaceuticos a base de tocoferol.
WO1989003689A1 (en) * 1987-10-19 1989-05-05 The Liposome Company, Inc. Tocopherol-based pharmaceutical systems
US5009819A (en) * 1987-11-12 1991-04-23 The Liposome Company, Inc. Taste moderating composition
US5948441A (en) * 1988-03-07 1999-09-07 The Liposome Company, Inc. Method for size separation of particles
US5049392A (en) * 1989-01-18 1991-09-17 The Liposome Company, Inc. Osmotically dependent vesicles
ATE115862T1 (de) * 1989-02-04 1995-01-15 Akzo Nobel Nv Tocole als impfstoffadjuvans.
JPH05500203A (ja) * 1989-02-17 1993-01-21 ザ リポソーム カンパニー,インコーポレイテッド 鼻腔内搬送用及び局所適用脂質賦形剤
EP0472639A4 (en) * 1989-05-15 1992-07-01 The Liposome Company, Inc. Accumulation of drugs into liposomes by a proton gradient
FR2657526B1 (fr) * 1990-01-31 1994-10-28 Lvmh Rech Utilisation d'un phosphate d'alpha-tocopherol, ou de l'un de ses derives, pour la preparation de compositions cosmetiques, dermatologiques, ou pharmaceutiques; compositions ainsi obtenues.
AU653325B2 (en) * 1990-02-12 1994-09-29 Lucky Limited A composition durably releasing bioactive polypeptides
US5525232A (en) * 1990-03-02 1996-06-11 The Liposome Company, Inc. Method for entrapment of cationic species in lemellar vesicles
IT1240354B (it) * 1990-03-30 1993-12-07 Poli Ind Chimica Spa Formulazioni liposomiali di farmaci antimicotici,antibatterici e/o antantiflogistici per applicazione locale e vaginale
DK0555229T3 (da) * 1990-07-31 1996-08-19 Liposome Co Inc Akkumulation af aminosyrer og peptider i liposomer
US5346703A (en) 1990-08-07 1994-09-13 Mediventures, Inc. Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels
CA2047969A1 (en) * 1990-08-17 1992-02-18 Thomas D. Madden Benzoporphyrin vesicles
US5091111A (en) * 1990-09-19 1992-02-25 S. C. Johnson & Son, Inc. Aqueous emulsion and aersol delivery system using same
US5145604A (en) * 1990-09-19 1992-09-08 S. C. Johnson & Son, Inc. Aqueous emulsion and aerosol delivery system using same
GB9111611D0 (en) * 1991-05-30 1991-07-24 Sandoz Ltd Liposomes
US5318780A (en) * 1991-10-30 1994-06-07 Mediventures Inc. Medical uses of in situ formed gels
JPH08505312A (ja) * 1992-10-16 1996-06-11 ザックセ,アンドレアス 液状分散系を製造する方法及び装置
KR940011013A (ko) * 1992-11-27 1994-06-20 최근선 서방성 소마트로핀 제제의 제조방법
EP0692961A1 (de) * 1993-04-02 1996-01-24 The Liposome Company, Inc. Herstellungsverfahren fuer liposomen
JPH08510748A (ja) * 1993-05-21 1996-11-12 ザ リポソーム カンパニー、インコーポレーテッド リポソームが誘発する生理的副作用の低減
JP3479535B2 (ja) 1993-07-08 2003-12-15 ザ リポソーム カンパニー、インコーポレーテッド リポソームの粒径を制御する方法
DE59409377D1 (de) * 1993-10-22 2000-06-29 Hexal Ag Pharmazeutische zusammensetzung mit cyclosporin a, einen vitamin e derivat und einen emulgator
US5716526A (en) * 1994-01-14 1998-02-10 The Liposome Company, Inc. Method of separating materials from liposomes or lipid complexes
US6051573A (en) * 1994-06-28 2000-04-18 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with non-steroidal glucocorticoid antagonists
HU215966B (hu) * 1994-11-21 1999-07-28 BIOGAL Gyógyszergyár Rt. Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
US6696413B2 (en) 1995-06-16 2004-02-24 Hexal Ag Pharmaceutical preparation with cyclosporin A
JPH10508322A (ja) 1995-10-12 1998-08-18 スーパーゲン,インコーポレイティド 5βステロイドのリポソーム配合物
US5763423A (en) * 1996-01-04 1998-06-09 Clarion Pharmaeuticals Inc. Pharmaceutical compositions, novel uses, and novel form of tocopherylphosphocholine
US6139872A (en) * 1996-08-14 2000-10-31 Henkel Corporation Method of producing a vitamin product
US6022560A (en) * 1996-08-27 2000-02-08 Clarion Pharmaceuticals Inc. Pharmaceutical compositions, novel uses, and novel form of α-tocopherylphosphocholine
EP0963196B1 (de) * 1996-09-27 2005-01-19 Jagotec Ag Arzneistoffverabreichungssystem mit hyaluronsäure
KR19990071255A (ko) 1998-02-28 1999-09-15 성재갑 소마토트로핀과 비타민의 합제 조성물
US6228385B1 (en) 1999-03-15 2001-05-08 Kimberly-Clark Worldwide Inc. Liquid antimicrobial, skin moisturizing formulation
US7314637B1 (en) 1999-06-29 2008-01-01 Neopharm, Inc. Method of administering liposomal encapsulated taxane
US6146659A (en) * 1998-07-01 2000-11-14 Neopharm, Inc. Method of administering liposomal encapsulated taxane
US6203778B1 (en) * 1998-12-08 2001-03-20 The Regents Of The University Of California Particulate radiopaque contrast agent for diagnostic imaging and microvascular characterization
ATE404172T1 (de) 1998-12-30 2008-08-15 Dexcel Ltd Dispergierbares konzentrat zur verabreichung von cyclosporin
AU4053700A (en) * 1999-04-02 2000-10-23 Washington State University Research Foundation Enhanced tissue and subcellular delivery of vitamin e compounds
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
FR2840614B1 (fr) 2002-06-07 2004-08-27 Flamel Tech Sa Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques
US20040115271A1 (en) * 2002-06-21 2004-06-17 Alex Sacharoff Hydration compositions for corneal pre-surgery treatment
US7718189B2 (en) 2002-10-29 2010-05-18 Transave, Inc. Sustained release of antiinfectives
BRPI0407096A (pt) * 2003-02-03 2006-01-24 Neopharm Inc Taxano encapsulado em lipossomo estável, estéril e filtrável e outros fármacos antineoplásicos
FR2855521B1 (fr) 2003-05-28 2005-08-05 Flamel Tech Sa Polyaminoacides fonctionnalises par au moins un groupement h ydrophobe et leurs applications notamment therapeutiques.
EP1547674A1 (de) * 2003-12-23 2005-06-29 MediGene Oncology GmbH Verfahren zur Herstellung von Kolloidteilchen
US9107824B2 (en) 2005-11-08 2015-08-18 Insmed Incorporated Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
EP3067047B1 (de) 2005-12-08 2022-04-20 Insmed Incorporated Antiinfektive zusammensetzungen auf lipidbasis zur behandlung von lungeninfekten
US20070134277A1 (en) * 2005-12-09 2007-06-14 Children's Medical Center Corporation Pharmaceutical formulation for sulfur-containing drugs in liquid dosage forms
US8258164B2 (en) * 2006-09-12 2012-09-04 Curatek Pharmaceuticals Holding, Inc. Nitroimidazole composition and method
US9211286B2 (en) * 2006-09-12 2015-12-15 Curatek Pharmaceuticals Holding, Inc. Terconazole composition and method
WO2008137717A1 (en) 2007-05-04 2008-11-13 Transave, Inc. Compositions of multicationic drugs for reducing interactions with polyanionic biomolecules and methods and uses thereof
US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
EP2166837A4 (de) * 2007-06-19 2011-12-21 Prugen Inc Wirkstoffkombination zur behandlung von hauterkrankungen
US20110082118A1 (en) * 2007-06-19 2011-04-07 Bhiku Patel Onychomycosis Treatment Delivery System
US20110076261A1 (en) * 2007-06-19 2011-03-31 Bhiku Patel Antifungal Drug Delivery System
FR2921259B1 (fr) * 2007-09-26 2015-02-13 Lvmh Rech Utilisation cosmetique du phosphate de tocopherol comme agent anti-vieillissement de la peau
PL2852391T3 (pl) 2012-05-21 2022-04-11 Insmed Incorporated Układy do leczenia infekcji płuc
DK2892524T3 (da) 2012-09-04 2021-01-25 Eleison Pharmaceuticals LLC Forebyggelse af pulmonalt kræfttilbagefald med lipid-komplekseret cisplatin
US10124066B2 (en) 2012-11-29 2018-11-13 Insmed Incorporated Stabilized vancomycin formulations
EP3041831B1 (de) 2013-09-06 2019-10-23 Research Development Foundation Alpha-tea-salzformen: zusammensetzungen und verwendungen zur behandlung von krankheiten
HUP1300621A2 (hu) 2013-10-31 2015-05-28 Richter Gedeon Nyrt Steril, tetszõleges részecskeméretû, liposzómák elõállítása zárt rendszerû folyamatos extrúzióval
LT3466432T (lt) 2014-05-15 2020-12-28 Insmed Incorporated Būdai, skirti plaučių netuberkuliozinėms mikobakterinėms infekcijoms gydyti
US20180200186A1 (en) * 2015-07-09 2018-07-19 Insmed Incorporated Compositions and methods for treating lung diseases and lung injury
CN108136023B (zh) 2015-08-12 2021-07-27 北卡罗莱纳州立大学 血小板膜包覆的药物递送系统
WO2017204896A1 (en) * 2016-05-26 2017-11-30 Becton, Dickinson And Company Methods and devices for liposome preparation by centrifugation
EP3773505B1 (de) 2018-03-30 2026-04-29 Insmed Incorporated Verfahren zur kontinuierlichen herstellung von liposomalen arzneimittelprodukten
JP7449275B2 (ja) 2018-05-02 2024-03-13 インスメッド インコーポレイテッド リポソーム薬物製剤の製造方法
US10736847B2 (en) 2018-07-03 2020-08-11 Becton, Dickinson And Company Inverting device for liposome preparation by centrifugation
EP4312536A1 (de) 2021-04-01 2024-02-07 Vestaron Corporation Liposomformulierungen zur pestizidabgabe und verfahren zur herstellung und verwendung davon
JP2025521093A (ja) 2022-05-10 2025-07-08 ベクトン・ディキンソン・アンド・カンパニー 真空媒介リポソーム調製のためのシステムおよびその使用方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1173179A (en) * 1967-09-29 1969-12-03 Samuel Ruben Method of Producing Micro-Perforated Stainless Steel Sheets
US3136695A (en) * 1961-03-10 1964-06-09 Strong Cobb Arner Inc Anhydrous thixotropic gel sustained release therapeutic compositions and method of preparation
US3719690A (en) * 1969-11-13 1973-03-06 Eisai Co Ltd Basic amino-acid salts of tocopherylsuccinate
US3993754A (en) * 1974-10-09 1976-11-23 The United States Of America As Represented By The United States Energy Research And Development Administration Liposome-encapsulated actinomycin for cancer chemotherapy
US4086257A (en) * 1976-10-12 1978-04-25 Sears Barry D Phosphatidyl quaternary ammonium compounds
US4088576A (en) * 1976-12-13 1978-05-09 Mott Lambert H Method of manufacture of tubular inertial filter
CH624011A5 (de) * 1977-08-05 1981-07-15 Battelle Memorial Institute
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4263428A (en) * 1978-03-24 1981-04-21 The Regents Of The University Of California Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
US4193983A (en) * 1978-05-16 1980-03-18 Syva Company Labeled liposome particle compositions and immunoassays therewith
FR2438481A1 (fr) * 1978-10-11 1980-05-09 Bugard Pierre Complexe lipoproteique normalisant l'efficacite de la vitamine e et des antioxydants de synthese
GR73668B (de) * 1978-11-21 1984-03-28 Hoffmann La Roche
DE3000483A1 (de) * 1979-01-09 1980-07-17 Fuji Photo Film Co Ltd Mikrokapseln fuer immunologische bestimmungen
CA1173360A (en) * 1979-06-22 1984-08-28 Jurg Schrank Pharmaceutical preparations
DE3068743D1 (en) * 1980-01-16 1984-08-30 Weder Hans G Process and dialysis-installation for the preparation of bilayer-vesicles and their use
US4376118A (en) * 1980-10-06 1983-03-08 Miles Laboratories, Inc. Stable nonaqueous solution of tetracycline salt
GR77320B (de) * 1980-12-22 1984-09-11 Procter & Gamble
US4522803A (en) * 1983-02-04 1985-06-11 The Liposome Company, Inc. Stable plurilamellar vesicles, their preparation and use
EP0153955A1 (de) * 1983-09-06 1985-09-11 Health Research, Inc. Verfahren zum verabreichen von liposomen zum herabsetzen der toxizität eines antitumor-arzneimittels
US4721612A (en) * 1984-04-12 1988-01-26 The Liposome Company, Inc. Steroidal liposomes
US4891208A (en) * 1985-04-10 1990-01-02 The Liposome Company, Inc. Steroidal liposomes
US4665204A (en) * 1985-06-27 1987-05-12 Henkel Corporation Diester derivatives of tocopherol
JP2634047B2 (ja) * 1985-10-15 1997-07-23 ザ リポソ−ム カンパニ−,インコ−ポレイテツド アルファトコフェロールをベースとした小胞体
JP2894445B2 (ja) * 1997-02-12 1999-05-24 日本たばこ産業株式会社 Cetp活性阻害剤として有効な化合物

Also Published As

Publication number Publication date
EP0460720B1 (de) 1996-08-14
EP0243446B1 (de) 1995-04-19
IL80267A0 (en) 1987-01-30
JP2848583B2 (ja) 1999-01-20
AU6543786A (en) 1987-05-05
EP0460720A2 (de) 1991-12-11
DE3650556T2 (de) 1997-02-13
DE3650556D1 (de) 1996-09-19
EP0243446A1 (de) 1987-11-04
JPH0834745A (ja) 1996-02-06
ATE141156T1 (de) 1996-08-15
EP0460720A3 (en) 1992-01-02
US4861580A (en) 1989-08-29
CA1315678C (en) 1993-04-06
DE3650302D1 (de) 1995-05-24
DE3650302T2 (de) 1995-09-07
EP0243446A4 (de) 1988-06-23
WO1987002219A1 (en) 1987-04-23

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