ATE121394T1 - Konjugierte gamma-hydroxybutenolid-derivate und sie als aktiver wirkstoff enthaltende mittel gegen magengeschwüre. - Google Patents
Konjugierte gamma-hydroxybutenolid-derivate und sie als aktiver wirkstoff enthaltende mittel gegen magengeschwüre.Info
- Publication number
- ATE121394T1 ATE121394T1 AT90117097T AT90117097T ATE121394T1 AT E121394 T1 ATE121394 T1 AT E121394T1 AT 90117097 T AT90117097 T AT 90117097T AT 90117097 T AT90117097 T AT 90117097T AT E121394 T1 ATE121394 T1 AT E121394T1
- Authority
- AT
- Austria
- Prior art keywords
- hydroxybutenolide
- group
- derivatives
- active ingredients
- groups
- Prior art date
Links
- 239000004480 active ingredient Substances 0.000 title abstract 2
- 208000007107 Stomach Ulcer Diseases 0.000 title 1
- 201000005917 gastric ulcer Diseases 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 239000003699 antiulcer agent Substances 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/60—Two oxygen atoms, e.g. succinic anhydride
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1245754A JP2790335B2 (ja) | 1989-09-20 | 1989-09-20 | 共役γ―オキシブテノライド化合物およびこれを有効成分とする抗潰瘍剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE121394T1 true ATE121394T1 (de) | 1995-05-15 |
Family
ID=17138301
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90117097T ATE121394T1 (de) | 1989-09-20 | 1990-09-05 | Konjugierte gamma-hydroxybutenolid-derivate und sie als aktiver wirkstoff enthaltende mittel gegen magengeschwüre. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5084464A (de) |
| EP (1) | EP0418655B1 (de) |
| JP (1) | JP2790335B2 (de) |
| AT (1) | ATE121394T1 (de) |
| DE (1) | DE69018741T2 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3938468A1 (de) * | 1989-11-18 | 1991-05-23 | Basf Ag | 1,1-dialkoxy-2-oxo-6-aryl-3,5-alkadiene |
| US5508302A (en) * | 1994-09-28 | 1996-04-16 | American Home Products Corporation | Phospholipase A2 inhibitors |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5916884A (ja) * | 1982-07-19 | 1984-01-28 | Fujisawa Pharmaceut Co Ltd | 新規フラン化合物 |
| US4789749A (en) * | 1984-06-18 | 1988-12-06 | The Regents Of The University Of California | Manoalide analogs |
| JPS61212578A (ja) * | 1985-03-15 | 1986-09-20 | Nippon Soda Co Ltd | ２−フラノン誘導体及びその製造方法 |
| ES8707946A1 (es) * | 1985-07-01 | 1987-09-01 | Lilly Co Eli | Un procedimiento para la preparacion de derivados de furanona. |
| JPH0222271A (ja) * | 1988-07-11 | 1990-01-25 | Kuraray Co Ltd | 共役γ−オキシブテノライド化合物およびこれを有効成分とする抗潰瘍剤 |
| JPH0676067B2 (ja) * | 1988-12-17 | 1994-09-28 | 三菱自動車エンジニアリング株式会社 | トラックの車台フレーム |
-
1989
- 1989-09-20 JP JP1245754A patent/JP2790335B2/ja not_active Expired - Fee Related
-
1990
- 1990-09-05 EP EP90117097A patent/EP0418655B1/de not_active Expired - Lifetime
- 1990-09-05 DE DE69018741T patent/DE69018741T2/de not_active Expired - Fee Related
- 1990-09-05 AT AT90117097T patent/ATE121394T1/de not_active IP Right Cessation
- 1990-09-13 US US07/583,946 patent/US5084464A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH03106870A (ja) | 1991-05-07 |
| EP0418655A3 (en) | 1991-12-18 |
| JP2790335B2 (ja) | 1998-08-27 |
| EP0418655B1 (de) | 1995-04-19 |
| EP0418655A2 (de) | 1991-03-27 |
| US5084464A (en) | 1992-01-28 |
| DE69018741D1 (de) | 1995-05-24 |
| DE69018741T2 (de) | 1995-10-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |