ATE121939T1 - Ascorbinsäure-tocopheryl-phosphatdiester zur hemmung der maillard-reaktion. - Google Patents

Ascorbinsäure-tocopheryl-phosphatdiester zur hemmung der maillard-reaktion.

Info

Publication number: ATE121939T1
Authority: AT; Austria
Prior art keywords: inhibiting; ascorbic acid; maillard reaction; phosphate diester; tocopheryl phosphate
Prior art date: 1989-11-21

Application number

AT90122218T

Other languages

English (en)

Inventor

Jun Inoue

Original Assignee

Senju Pharma Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-11-21

Filing date

1990-11-20

Publication date

1995-05-15

1990-11-20 Application filed by Senju Pharma Co filed Critical Senju Pharma Co

1995-05-15 Application granted granted Critical

1995-05-15 Publication of ATE121939T1 publication Critical patent/ATE121939T1/de

Links

CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 title 2
JUIUXBHZFNHITF-IEOSBIPESA-N [(2r)-2,5,7,8-tetramethyl-2-[(4r,8r)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] dihydrogen phosphate Chemical compound OP(=O)(O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C JUIUXBHZFNHITF-IEOSBIPESA-N 0.000 title 1
229960005070 ascorbic acid Drugs 0.000 title 1
235000010323 ascorbic acid Nutrition 0.000 title 1
239000011668 ascorbic acid Substances 0.000 title 1
230000002401 inhibitory effect Effects 0.000 title 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
208000002249 Diabetes Complications Diseases 0.000 abstract 1
206010012655 Diabetic complications Diseases 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
238000011282 treatment Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Diabetes (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Hematology (AREA)
Obesity (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Medicinal Preparation (AREA)
Cosmetics (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT90122218T 1989-11-21 1990-11-20 Ascorbinsäure-tocopheryl-phosphatdiester zur hemmung der maillard-reaktion. ATE121939T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP1304479A JP2854631B2 (ja)	1989-11-21	1989-11-21	糖尿病合併症および老化によって引き起こされる疾患の予防・治療剤

Publications (1)

Publication Number	Publication Date
ATE121939T1 true ATE121939T1 (de)	1995-05-15

Family

ID=17933520

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90122218T ATE121939T1 (de)	1989-11-21	1990-11-20	Ascorbinsäure-tocopheryl-phosphatdiester zur hemmung der maillard-reaktion.

Country Status (8)

Country	Link
EP (1)	EP0430045B1 (de)
JP (1)	JP2854631B2 (de)
KR (1)	KR910009272A (de)
AT (1)	ATE121939T1 (de)
CA (1)	CA2029420C (de)
DE (1)	DE69019111T2 (de)
DK (1)	DK0430045T3 (de)
ES (1)	ES2071725T3 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH05286848A (ja) *	1992-04-10	1993-11-02	Senju Pharmaceut Co Ltd	浴用剤
EP0679088B1 (de)	1992-09-29	2002-07-10	Inhale Therapeutic Systems	Pulmonale abgabe von aktiven fragmenten des parathormons
CA2129509A1 (en) *	1993-09-10	1995-03-11	Kazumi Ogata	Pharmaceutical composition for renal disorder and a dialysis solution for extracorporeal hemodialysis
ATE416755T1 (de)	1994-03-07	2008-12-15	Nektar Therapeutics	Verfahren und zusammensetzung für die pulmonale darreichung von insulin
US5955448A (en) *	1994-08-19	1999-09-21	Quadrant Holdings Cambridge Limited	Method for stabilization of biological substances during drying and subsequent storage and compositions thereof
GB2288732B (en) *	1994-04-13	1998-04-29	Quadrant Holdings Cambridge	Pharmaceutical compositions
JP3362501B2 (ja) *	1994-04-28	2003-01-07	千寿製薬株式会社	角膜障害治療剤
JP3396953B2 (ja) *	1994-05-10	2003-04-14	千寿製薬株式会社	網膜疾患予防・治療剤
JPH07330501A (ja)	1994-06-14	1995-12-19	Senju Pharmaceut Co Ltd	肝保存剤および肝保存方法
US6290991B1 (en)	1994-12-02	2001-09-18	Quandrant Holdings Cambridge Limited	Solid dose delivery vehicle and methods of making same
CA2152693A1 (en) *	1994-08-05	1996-02-06	Kazumi Ogata	Therapeutic composition for pancreatitis
US5795912A (en) *	1995-04-26	1998-08-18	Senju Pharmaceutical, Co., Ltd.	Therapeutic composition for corneal impairment
CA2179940A1 (en) *	1995-07-18	1997-01-19	Kazumi Ogata	Antiallergic composition comprising a phosphoric diester compound
CA2186654A1 (en) *	1995-10-13	1997-04-14	Masayuki Nakamura	Phosphoric diester
US6565885B1 (en)	1997-09-29	2003-05-20	Inhale Therapeutic Systems, Inc.	Methods of spray drying pharmaceutical compositions
US6309623B1 (en)	1997-09-29	2001-10-30	Inhale Therapeutic Systems, Inc.	Stabilized preparations for use in metered dose inhalers
US20060165606A1 (en)	1997-09-29	2006-07-27	Nektar Therapeutics	Pulmonary delivery particles comprising water insoluble or crystalline active agents
CA2319020A1 (en) *	1998-02-03	1999-08-12	Senju Pharmaceutical Co., Ltd.	Pharmaceutical compositions for prevention and treatment of neurodegenarative diseases
PT1280520E (pt)	2000-05-10	2014-12-16	Novartis Ag	Pós à base de fosfolípidos para administração de fármacos
US8404217B2 (en)	2000-05-10	2013-03-26	Novartis Ag	Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7871598B1 (en)	2000-05-10	2011-01-18	Novartis Ag	Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
AUPR549901A0 (en)	2001-06-06	2001-07-12	Vital Health Sciences Pty Ltd	Topical formulation containing tocopheryl phosphates
BR0211673A (pt)	2001-07-27	2004-07-13	Vital Health Sciences Pty Ltd	Terapia dermal utilizando derivados de fosfato de agentes de transferência de elétrons
AUPR684801A0 (en) *	2001-08-06	2001-08-30	Vital Health Sciences Pty Ltd	Supplement therapy
MXPA04001779A (es) *	2001-09-26	2004-05-31	Vital Health Sciences Pty Ltd	Modulacion de almacenamiento de vitamina.
PT1458360E (pt)	2001-12-19	2011-07-13	Novartis Ag	Derivados de indole como agonistas do recetor s1p1
AU2002950713A0 (en)	2002-08-09	2002-09-12	Vital Health Sciences Pty Ltd	Carrier
JP4847437B2 (ja)	2004-03-03	2011-12-28	バイタルヘルスサイエンシズプロプライアタリーリミティド	アルカロイド製剤
JP2008531603A (ja) *	2005-03-03	2008-08-14	バイタルヘルスサイエンシズプロプライアタリーリミティド	脂質低下特性を有する化合物
US9168216B2 (en)	2005-06-17	2015-10-27	Vital Health Sciences Pty. Ltd.	Carrier comprising one or more di and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof
EP2531047B1 (de)	2010-02-05	2024-11-13	Phosphagenics Limited	Träger mit einem nichtneutralisierten tocopherylphosphat
ES2829386T3 (es)	2010-03-30	2021-05-31	Phosphagenics Ltd	Parche de administración transdérmica
WO2012122586A1 (en)	2011-03-15	2012-09-20	Phosphagenics Limited	New composition
CN104297412B (zh) *	2014-10-17	2015-12-02	徐州工程学院	一种蛋白粉新鲜度的测定方法
MX383940B (es)	2015-12-09	2025-03-14	Phosphagenics Ltd	Formulación farmacéutica que contiene tocol fosfato.
IL267006B2 (en)	2016-12-21	2024-11-01	Phosphagenics Ltd	Process for phosphorylation of a complex alcohol with p4o10 at high temperatures, and products thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS59219295A (ja) *	1983-05-30	1984-12-10	Senjiyu Seiyaku Kk	リン酸ジエステルまたはその塩およびそれらの製造法
JPS62205091A (ja) *	1986-03-04	1987-09-09	Senjiyu Seiyaku Kk	新規なリン酸ジエステルならびにその塩、その製造法およびそれを含有する製剤
JP2546687B2 (ja) *	1987-09-11	1996-10-23	千寿製薬株式会社	リン酸ジエステルまたはその塩からなる抗酸化剤
PH25859A (en) *	1988-01-11	1991-12-02	Takeda Chemical Industries Ltd	Composition for treatment of ischemic disorder

1989
- 1989-11-21 JP JP1304479A patent/JP2854631B2/ja not_active Expired - Lifetime
1990
- 1990-11-07 CA CA002029420A patent/CA2029420C/en not_active Expired - Fee Related
- 1990-11-16 KR KR1019900018594A patent/KR910009272A/ko not_active Ceased
- 1990-11-20 DK DK90122218.2T patent/DK0430045T3/da active
- 1990-11-20 ES ES90122218T patent/ES2071725T3/es not_active Expired - Lifetime
- 1990-11-20 DE DE69019111T patent/DE69019111T2/de not_active Expired - Fee Related
- 1990-11-20 EP EP90122218A patent/EP0430045B1/de not_active Expired - Lifetime
- 1990-11-20 AT AT90122218T patent/ATE121939T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0430045B1 (de)	1995-05-03
JPH03161444A (ja)	1991-07-11
EP0430045A3 (en)	1991-11-06
DE69019111T2 (de)	1995-08-31
DK0430045T3 (da)	1995-07-17
JP2854631B2 (ja)	1999-02-03
ES2071725T3 (es)	1995-07-01
EP0430045A2 (de)	1991-06-05
KR910009272A (ko)	1991-06-28
CA2029420C (en)	2000-09-19
CA2029420A1 (en)	1991-05-22
DE69019111D1 (de)	1995-06-08

Legal Events

Date	Code	Title	Description
1995-11-15	UEP	Publication of translation of european patent specification
1999-08-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE121939T1 (de)	1995-05-15	Ascorbinsäure-tocopheryl-phosphatdiester zur hemmung der maillard-reaktion.
ATE152352T1 (de)	1997-05-15	Pharmazeutische zusammensetzungen zur hemmung der maillardreaktion
DE69229442D1 (de)	1999-07-22	Substituierte dibenzooxazepin-verbindungen, pharmazeutische zusammensetzungen und verfahren zur verwendung
ES2111352T3 (es)	1998-03-01	Uso de diester fosfato para el tratamiento de enfermedades retinianas.
ATE71092T1 (de)	1992-01-15	Hydroxybutenolid-derivate, ihre herstellung und ihre verwendung.
ATE38982T1 (de)	1988-12-15	Guanidinmethylcyclohexancarbonsaeure-derivate, verfahren zur herstellung und pharmazeutische mittel.
DK288787A (da)	1987-12-10	Kondenserede imidazo-heterocycliske forbindelser, fremgangsmaade til deres fremstilling, og deres anvendelse som laegemidler
ATE92315T1 (de)	1993-08-15	Aminosaeurederivate enthaltende antikonvulsive zusammensetzungen und verwendung dieser aminosaeurederivate.
NZ228182A (en)	1990-08-28	Substituted 4,5,6,7-tetrahydroisothiazolo(4,5-c) pyridine derivatives and pharmaceutical compositions; methods for preparation
HUT46214A (en)	1988-10-28	Process for producing medical preparation suitable for treatment of peptic ulcer
IT1223395B (it)	1990-09-19	Composti ad attivita' cardiovascolare
AU7424394A (en)	1995-04-13	3- or 4-glycosyloxybenzopyran derivatives and antiallergic agents containing the derivatives as active ingredients
LT2199B (lt)	1993-10-15	2-triazolidinono dariniu gavimo budas
ES2057110T3 (es)	1994-10-16	Utilizacion de isoxazolinonas como farmacos con accion sobre el cerebro.
ZA885358B (en)	1989-03-29	Uricosuric composition
ATE81466T1 (de)	1992-10-15	Verwendung von 2-oxo-imidazolidin-derivaten zur prophylaxe und zur behandlung von herzinsuffizienz.
ATE81465T1 (de)	1992-10-15	Verwendung von 2-oxo-imidazolidin-derivaten zur behandlung von nierenkrankheiten.