ATE123018T1 - Verfahren zur herstellung von 2,4,6-triiodo-5- amino-n-alkyl-isophthalsäure. - Google Patents

Verfahren zur herstellung von 2,4,6-triiodo-5- amino-n-alkyl-isophthalsäure.

Info

Publication number
ATE123018T1
ATE123018T1 AT89905013T AT89905013T ATE123018T1 AT E123018 T1 ATE123018 T1 AT E123018T1 AT 89905013 T AT89905013 T AT 89905013T AT 89905013 T AT89905013 T AT 89905013T AT E123018 T1 ATE123018 T1 AT E123018T1
Authority
AT
Austria
Prior art keywords
substrate
amino
iodine halide
added
instant
Prior art date
Application number
AT89905013T
Other languages
English (en)
Inventor
Gregory D Cross
Robert C Chapman
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Application granted granted Critical
Publication of ATE123018T1 publication Critical patent/ATE123018T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
AT89905013T 1988-04-06 1989-03-29 Verfahren zur herstellung von 2,4,6-triiodo-5- amino-n-alkyl-isophthalsäure. ATE123018T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17824588A 1988-04-06 1988-04-06

Publications (1)

Publication Number Publication Date
ATE123018T1 true ATE123018T1 (de) 1995-06-15

Family

ID=22651791

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89905013T ATE123018T1 (de) 1988-04-06 1989-03-29 Verfahren zur herstellung von 2,4,6-triiodo-5- amino-n-alkyl-isophthalsäure.

Country Status (7)

Country Link
EP (1) EP0408654B1 (de)
JP (1) JP2640381B2 (de)
AT (1) ATE123018T1 (de)
AU (3) AU623403B2 (de)
CA (1) CA1331626C (de)
DE (1) DE68922850T2 (de)
WO (1) WO1989009766A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013865A (en) * 1988-04-06 1991-05-07 Mallinckrodt, Inc. Process for the preparation of 2,4,6-triiodo-5-amino-N-alkylisophthalamic acid and 2,4,6-triiodo-5-amino-isophthalamide compounds
US6137006A (en) * 1997-05-23 2000-10-24 Nycomed Imaging As Preparation of tri-iodo benzene compounds
GB9710725D0 (en) 1997-05-23 1997-07-16 Nycomed Imaging As Process
GB9710728D0 (en) * 1997-05-23 1997-07-16 Nycomed Imaging As Method

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD49852A (de) *
US3145197A (en) * 1961-06-26 1964-08-18 Mallinckrodt Chemical Works 5-acetamido-nu-alkyl-2, 4, 6-trhodoiso-phthalamic acid compounds
CA1327600C (en) * 1987-05-22 1994-03-08 Ernest Felder Process for the preparation of 5-acylamino-2,4,6- triiodo-or tribromo-benzoic acid derivatives and corresponding novel 5-acylamino-2,4,6-triiodo or tribromo-benzoic acid derivatives obtained by said process
US5013865A (en) * 1988-04-06 1991-05-07 Mallinckrodt, Inc. Process for the preparation of 2,4,6-triiodo-5-amino-N-alkylisophthalamic acid and 2,4,6-triiodo-5-amino-isophthalamide compounds
DE3937118A1 (de) * 1989-11-03 1991-05-08 Schering Ag Nichtionische roentgenkontrastmittel mit hohem jodgehalt

Also Published As

Publication number Publication date
JPH03505086A (ja) 1991-11-07
AU639627B2 (en) 1993-07-29
EP0408654A1 (de) 1991-01-23
AU623403B2 (en) 1992-05-14
DE68922850D1 (de) 1995-06-29
WO1989009766A2 (en) 1989-10-19
AU3441889A (en) 1989-11-03
JP2640381B2 (ja) 1997-08-13
AU1028592A (en) 1992-02-27
CA1331626C (en) 1994-08-23
AU1010992A (en) 1992-02-27
AU651167B2 (en) 1994-07-14
WO1989009766A3 (en) 1989-11-16
EP0408654B1 (de) 1995-05-24
DE68922850T2 (de) 1995-12-21

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