ATE123286T1 - Verfahren zur herstellung von 3-alkoxymethyl cephalosporinderivate. - Google Patents

Verfahren zur herstellung von 3-alkoxymethyl cephalosporinderivate.

Info

Publication number: ATE123286T1
Authority: AT; Austria
Prior art keywords: compound; formula; alkoxymethyl; producing; cephalosporine derivatives
Prior art date: 1990-11-07

Application number

AT91310289T

Other languages

English (en)

Inventor

Yukio C O Sankyo Orga Hirayama

Takatsu-Ku

Syuji C O Sankyo Organi Sayama

Takatsu-Ku Kuji

Kiyomi C O Sankyo Or Yamaguchi

Shigeru C O Sankyo Or Miyamoto

Yasuo C O Sankyo Org Takahashi

Takatsu Kuji

Keisuke C O Sankyo Organi Kato

Tomio C O Sankyo Company Sasao

Nakaharakamijuku Aza

Kiyoshi C O Sankyo Comp Iijima

Chome

Original Assignee

Sankyo Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-11-07

Filing date

1991-11-06

Publication date

1995-06-15

1991-11-06 Application filed by Sankyo Co filed Critical Sankyo Co

1995-06-15 Application granted granted Critical

1995-06-15 Publication of ATE123286T1 publication Critical patent/ATE123286T1/de

Links

HOKIDJSKDBPKTQ-UHFFFAOYSA-N 3-(acetyloxymethyl)-7-[(5-amino-5-carboxypentanoyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Chemical class S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)C(NC(=O)CCCC(N)C(O)=O)C12 HOKIDJSKDBPKTQ-UHFFFAOYSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 6
150000003839 salts Chemical class 0.000 abstract 2
HSHGZXNAXBPPDL-HZGVNTEJSA-N 7beta-aminocephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H]([NH3+])[C@@H]12 HSHGZXNAXBPPDL-HZGVNTEJSA-N 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Cephalosporin Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT91310289T 1990-11-07 1991-11-06 Verfahren zur herstellung von 3-alkoxymethyl cephalosporinderivate. ATE123286T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP30207190		1990-11-07

Publications (1)

Publication Number	Publication Date
ATE123286T1 true ATE123286T1 (de)	1995-06-15

Family

ID=17904568

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91310289T ATE123286T1 (de)	1990-11-07	1991-11-06	Verfahren zur herstellung von 3-alkoxymethyl cephalosporinderivate.

Country Status (10)

Country	Link
US (1)	US5451675A (de)
EP (1)	EP0485204B1 (de)
JP (1)	JP3206821B2 (de)
KR (1)	KR0140196B1 (de)
AT (1)	ATE123286T1 (de)
DE (1)	DE69110107T2 (de)
DK (1)	DK0485204T3 (de)
ES (1)	ES2075365T3 (de)
HK (1)	HK1005452A1 (de)
IE (1)	IE68511B1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AT401177B (de) *	1993-10-22	1996-07-25	Biochemie Gmbh	Verfahren zur herstellung von 7-amino-3-cephem-4-carbonsäure-derivaten
KR100343434B1 (ko) *	1999-10-13	2002-07-11	민경윤	7-아미노-3-메톡시메틸-3-세펨-4-카복실산의 제조방법
IN192344B (de) *	2001-01-30	2004-04-10	Ranbaxy Lab Ltd
EP2758407A1 (de)	2011-09-20	2014-07-30	Dhanuka Laboratories Ltd.	Verbessertes verfahren für cefpodoximsäure
EP3426663B1 (de)	2016-03-07	2020-01-29	Dhanuka Laboratories Ltd.	Verfahren zur alkylierung der hydroxymethylgruppe an position -3 von cephalosporinen
CN105669701A (zh) *	2016-03-22	2016-06-15	陕西思尔生物科技有限公司	一种头孢泊肟酯中间体的合成方法
CN106478666B (zh) *	2016-09-22	2018-07-31	湖北凌晟药业有限公司	7-氨基-3-甲氧甲基-3-头孢烯-4-羧酸的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5896091A (ja) *	1981-12-01	1983-06-07	Sankyo Co Ltd	３−アルコキシメチルセフアロスポリン類の製造法
JPS59163387A (ja) *	1983-03-07	1984-09-14	Sankyo Co Ltd	３−アルコキシメチルセフアロスポリンの製造方法
AT384222B (de) *	1985-06-03	1987-10-12	Biochemie Gmbh	Verfahren zur herstellung von 7-amino-3alkoxymethyl-3-cephem-4-carbonsaeuren
DE3789412T2 (de) *	1986-10-02	1994-06-30	Asahi Chemical Ind	Verfahren zur Herstellung von 3-Alkoxymethylcephalosporinen.
JPS63115887A (ja) *	1986-11-04	1988-05-20	Asahi Chem Ind Co Ltd	７−アミノ−３−アルコキシメチルセフアロスポリン類の製造方法
JP2612493B2 (ja) *	1988-05-24	1997-05-21	旭化成工業株式会社	３―置換メチル―３―セフェム―４―カルボン酸類の製造方法
DE4004370A1 (de) *	1990-02-13	1991-08-14	Hoechst Ag	Verfahren zur herstellung von 7-amino-3-methoxymethyl-ceph-3-em-4-carbonsaeure

1991
- 1991-11-06 EP EP91310289A patent/EP0485204B1/de not_active Expired - Lifetime
- 1991-11-06 AT AT91310289T patent/ATE123286T1/de not_active IP Right Cessation
- 1991-11-06 DK DK91310289.3T patent/DK0485204T3/da active
- 1991-11-06 IE IE387291A patent/IE68511B1/en not_active IP Right Cessation
- 1991-11-06 DE DE69110107T patent/DE69110107T2/de not_active Expired - Fee Related
- 1991-11-06 JP JP29012291A patent/JP3206821B2/ja not_active Expired - Fee Related
- 1991-11-06 ES ES91310289T patent/ES2075365T3/es not_active Expired - Lifetime
- 1991-11-07 KR KR1019910019735A patent/KR0140196B1/ko not_active Expired - Fee Related
1993
- 1993-08-03 US US08/101,814 patent/US5451675A/en not_active Expired - Fee Related
1998
- 1998-05-27 HK HK98104571A patent/HK1005452A1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0485204A2 (de)	1992-05-13
KR920009833A (ko)	1992-06-25
IE68511B1 (en)	1996-06-26
IE913872A1 (en)	1992-05-20
KR0140196B1 (ko)	1998-06-01
JP3206821B2 (ja)	2001-09-10
DE69110107D1 (de)	1995-07-06
EP0485204B1 (de)	1995-05-31
EP0485204A3 (en)	1992-09-23
JPH04364188A (ja)	1992-12-16
DK0485204T3 (da)	1995-10-16
US5451675A (en)	1995-09-19
ES2075365T3 (es)	1995-10-01
DE69110107T2 (de)	1996-02-01
HK1005452A1 (en)	1999-01-08

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Legal Events

Date	Code	Title	Description
2006-08-15	REN	Ceased due to non-payment of the annual fee