ATE123652T1 - Antigene. - Google Patents

Antigene.

Info

Publication number
ATE123652T1
ATE123652T1 AT89302174T AT89302174T ATE123652T1 AT E123652 T1 ATE123652 T1 AT E123652T1 AT 89302174 T AT89302174 T AT 89302174T AT 89302174 T AT89302174 T AT 89302174T AT E123652 T1 ATE123652 T1 AT E123652T1
Authority
AT
Austria
Prior art keywords
antigen
fragments
antigens
recognise
antibodies
Prior art date
Application number
AT89302174T
Other languages
English (en)
Inventor
Peter C O Royal Liverpoo Stern
Nicholas C O Royal Liverp Hole
Original Assignee
Cancer Res Campaign Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888805240A external-priority patent/GB8805240D0/en
Priority claimed from GB888821078A external-priority patent/GB8821078D0/en
Application filed by Cancer Res Campaign Tech filed Critical Cancer Res Campaign Tech
Application granted granted Critical
Publication of ATE123652T1 publication Critical patent/ATE123652T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT89302174T 1988-03-04 1989-03-03 Antigene. ATE123652T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888805240A GB8805240D0 (en) 1988-03-04 1988-03-04 Improvements relating to antigen
GB888821078A GB8821078D0 (en) 1988-09-08 1988-09-08 Improvements relating to antigens

Publications (1)

Publication Number Publication Date
ATE123652T1 true ATE123652T1 (de) 1995-06-15

Family

ID=26293590

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89302174T ATE123652T1 (de) 1988-03-04 1989-03-03 Antigene.

Country Status (6)

Country Link
EP (2) EP0336562B1 (de)
AT (1) ATE123652T1 (de)
AU (1) AU3353989A (de)
DE (1) DE68923027D1 (de)
IE (1) IE890720L (de)
WO (1) WO1989007947A1 (de)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9601245D0 (sv) 1996-03-29 1996-03-29 Pharmacia Ab Chimeric superantigens and their use
TW517061B (en) 1996-03-29 2003-01-11 Pharmacia & Amp Upjohn Ab Modified/chimeric superantigens and their use
AU715845B2 (en) * 1996-12-05 2000-02-10 Macquarie Research Limited Electrophoresis separation methods
AUPO403496A0 (en) * 1996-12-05 1997-01-02 Macquarie Research Limited Electrophoresis separation methods
US6852703B1 (en) * 1997-06-04 2005-02-08 Oxford Biomedica (Uk) Limited Tumor targeted vector
US7276488B2 (en) 1997-06-04 2007-10-02 Oxford Biomedica (Uk) Limited Vector system
WO2002018645A2 (en) * 2000-08-28 2002-03-07 Oncomedx, Inc. 5t4 rna in plasma and serum as a marker for neoplastic disease
US7767422B2 (en) 1998-09-22 2010-08-03 Oncomedx, Inc. Detection of 5T4 RNA in plasma and serum
CA2351622A1 (en) 1998-11-18 2000-05-25 Oxford Biomedica (Uk) Limited Polypeptide
US7148035B1 (en) 1998-11-18 2006-12-12 Oxford Biomedica (Uk) Limited Polypeptide
GB2378704B (en) * 1998-11-18 2003-05-07 Oxford Biomedica Ltd Uses of 5t4 antigen
GB9825303D0 (en) * 1998-11-18 1999-01-13 Oxford Biomedica Ltd Vector
GB2370571B (en) * 1998-11-18 2003-05-07 Oxford Biomedica Ltd A modified 5t4 antigen
GB0400443D0 (en) 2004-01-09 2004-02-11 Oxford Biomedica Ltd Cascade
CA2391925A1 (en) * 1999-11-18 2001-05-25 Oxford Biomedica (Uk) Limited Antibodies
GB2371803A (en) * 1999-11-18 2002-08-07 Oxford Biomedica Ltd Antibodies
US7402666B2 (en) 2000-11-13 2008-07-22 Oxford Biomedica (Uk) Ltd. Nucleotide encoding canine 5T4 antigen
GB0126378D0 (en) 2001-11-02 2002-01-02 Oxford Biomedica Ltd Antigen
GB0203420D0 (en) 2002-02-13 2002-04-03 Oxford Biomedica Ltd Peptide
GB0203419D0 (en) 2002-02-13 2002-04-03 Oxford Biomedica Ltd Peptide
US7662625B2 (en) 2002-07-02 2010-02-16 Cancer Research Technology Limited Methods for detecting the differentiation status of cells using 5T4 antigen expression
GB0215287D0 (en) * 2002-07-02 2002-08-14 Oxford Biomedica Ltd 5T4 antigen expression
EP2045268B1 (de) 2005-05-13 2011-09-21 Oxford BioMedica (UK) Limited Vom Tumorantigen 5t4 abgeleitete Mhc-Klasse-I- und II-Peptidantigene
CA2645097C (en) 2006-03-10 2019-09-17 Wyeth Anti-5t4 antibodies and uses thereof
BRPI0719250A2 (pt) 2006-10-12 2015-06-16 Wyeth Corp Métodos e composições com opalescência reduzida.
GB0822836D0 (en) * 2008-12-15 2009-01-21 Oxford Biomedica Ltd Method
WO2010111659A1 (en) 2009-03-27 2010-09-30 Wyeth Llc Tumor-initiating cells and methods for using same
US8822663B2 (en) 2010-08-06 2014-09-02 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
DK4108671T3 (da) 2010-10-01 2025-01-06 Modernatx Inc Modificerede nukleosider, nukleotider og nukleinsyrer samt anvendelser deraf
JP2014511687A (ja) 2011-03-31 2014-05-19 モデルナ セラピューティクス インコーポレイテッド 工学操作された核酸の送達および製剤
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
JP6113737B2 (ja) 2011-10-03 2017-04-12 モデルナティエックス インコーポレイテッドModernaTX,Inc. 修飾型のヌクレオシド、ヌクレオチドおよび核酸、ならびにそれらの使用方法
KR20140102759A (ko) 2011-12-16 2014-08-22 모더나 세라퓨틱스, 인코포레이티드 변형된 뉴클레오사이드, 뉴클레오타이드 및 핵산 조성물
JP6254951B2 (ja) 2012-01-24 2017-12-27 ファイザー・インク 哺乳類の対象における5t4陽性循環腫瘍細胞を検出するための方法および5t4陽性がんの診断の方法
US9254311B2 (en) 2012-04-02 2016-02-09 Moderna Therapeutics, Inc. Modified polynucleotides for the production of proteins
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
EP2834259A4 (de) 2012-04-02 2016-08-24 Moderna Therapeutics Inc Modifizierte polynukleotide
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9597380B2 (en) 2012-11-26 2017-03-21 Modernatx, Inc. Terminally modified RNA
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
US10023626B2 (en) 2013-09-30 2018-07-17 Modernatx, Inc. Polynucleotides encoding immune modulating polypeptides
EP3052521A1 (de) 2013-10-03 2016-08-10 Moderna Therapeutics, Inc. Polynukleotide zur codierung von low-density-lipoprotein-rezeptor
SG11201803692PA (en) 2015-11-24 2018-06-28 Synthon Biopharmaceuticals Bv Anti-5t4 antibodies and antibody-drug conjugates
EP3411409B1 (de) 2016-01-10 2025-10-08 Neotx Therapeutics Ltd. Antikörper anti-pd-1/anti-pd-l1 zur stimulierung der durch superantigene vermittelten krebs immuntherapie
KR20230166145A (ko) 2017-03-15 2023-12-06 옥스포드 바이오메디카(유케이) 리미티드 방법
CN111227039A (zh) * 2018-11-29 2020-06-05 内蒙古伊利实业集团股份有限公司 脂肪球膜的提取方法、富含脂肪球膜的酸奶及制备方法
CN114025791A (zh) 2019-05-15 2022-02-08 尼奥克斯医疗有限公司 癌症治疗
US20230085724A1 (en) 2020-03-05 2023-03-23 Neotx Therapeutics Ltd. Methods and compositions for treating cancer with immune cells
IL320040A (en) * 2022-10-05 2025-06-01 Musc Found For Res Dev Superantigen conjugate vaccine for cancer treatment

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2571146B1 (fr) * 1984-10-01 1988-02-26 Centre Nat Rech Scient Antigenes carcino-foetaux du pancreas humain et un procede de purification, antiserum contre ces antigenes et son procede de preparation et compositions diagnostiques les contenant

Also Published As

Publication number Publication date
AU3353989A (en) 1989-09-22
WO1989007947A1 (en) 1989-09-08
EP0336562B1 (de) 1995-06-14
DE68923027D1 (de) 1995-07-20
IE890720L (en) 1989-09-04
EP0336562A1 (de) 1989-10-11
EP0403559A1 (de) 1990-12-27

Similar Documents

Publication Publication Date Title
ATE123652T1 (de) Antigene.
EP0823438A3 (de) Menschliches Mucin-Core-Protein: Peptid-Fragmente und Antikörper dagegen, sowohl deren Verwendung in Diagnoseverfahren und therapeutischen Methoden
DE69230545D1 (de) Antikörperderivate
HU9402220D0 (en) Bispecific trigger molecules recognizing lymphocyte antigen cd2 and tumor antigens
MX9603080A (es) Anticuerpos monoclonales inmuno-estimulantes.
NO179615C (no) Monoklonale antistoffer eller fragmenter derav som reagerer med kakektin, cellelinjer som produserer dem, prövesett som omfatter dem, samt anvendelse derav in vitro
FI913891A7 (fi) Uusi monoklonaalinen vasta-aine uutta antigeenia vastaan, joka liittyy ihmisen kasvaimiin
GR3029740T3 (en) Fragments of prion proteins.
OA08485A (fr) Monoclonal antibodies and antigen for human non-small cell lung carcinoma and certain other human carcinomas.
DE69433378D1 (de) Humane b-lymphoblastoiden zellinie welche anti-gangliosid-antikörper sekretiert
DE3586216D1 (de) Brusttumorassoziiertes antigen und monoklonale antikoerper dazu.
AU1971295A (en) Humanized monoclonal antibodies against human interleukin-4
EP0109434A4 (de) In vitro diagnoseverfahren unter verwendung von monoklonalen antikörpern gegen konnektive gewebeproteine.
DE3884646D1 (de) Humanes Karcinom-assoziertes Antigen und an dieses Antigen bindende Antikörper.
EP0307476A4 (en) Bilirubin antigen, monoclonal antibody therefor, process for their preparation, and their use
EP0299354A3 (en) Monoclonal antibodies against protein e7 of the human papilloma virus type 16, their production process and their use
IL83584A (en) Monoclonal antibodies against glycosylated human albumin,method and immunogens for raising said antibodies and their use in immunoassays
EP0262571A3 (en) Monoclonal antibodies against ifn-omega, process for preparing them and their use in the purification and detection of ifn-omega
ES2059539T3 (es) Metodo para la prevencion de la enfermedad del injerto frente al huesped.
AU7160887A (en) Antiparatypical antibodies, their use for detecting and treating auto-immune diseases
DE68907377D1 (de) Agens und geraet zur bestimmung von antigenen oder antikoerpern.
EP0334076A3 (en) Monoclonal antibody capable of recognizing an antigen associated with human arteriosclerosis, and process for preparing the same
EP0352328A4 (de) Menschliches monoklonales antikörper gegen aspergilli.
NO872633D0 (no) Monoklonalt antistoff mot humant plasminogen, samt fremstilling derav.
NO895007D0 (no) Simultan enzym-immunoanalyse for deteksjon av antigen og/eller antistoff i mennesker.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties