ATE124946T1 - Neuro-schützende mittel. - Google Patents

Neuro-schützende mittel.

Info

Publication number
ATE124946T1
ATE124946T1 AT92907045T AT92907045T ATE124946T1 AT E124946 T1 ATE124946 T1 AT E124946T1 AT 92907045 T AT92907045 T AT 92907045T AT 92907045 T AT92907045 T AT 92907045T AT E124946 T1 ATE124946 T1 AT E124946T1
Authority
AT
Austria
Prior art keywords
neuro
protective agents
hydrogen
perhaloalkyl
proviso
Prior art date
Application number
AT92907045T
Other languages
English (en)
Inventor
Wayne Everett Childers Jr
Magid Abdel-Megid Abou-Gharbia
Edward James Podlesny
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Application granted granted Critical
Publication of ATE124946T1 publication Critical patent/ATE124946T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT92907045T 1991-02-20 1992-02-14 Neuro-schützende mittel. ATE124946T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/658,283 US5508401A (en) 1991-02-20 1991-02-20 Substituted dibenzo[a,d]cycloheptene NMDA antagonists

Publications (1)

Publication Number Publication Date
ATE124946T1 true ATE124946T1 (de) 1995-07-15

Family

ID=24640618

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92907045T ATE124946T1 (de) 1991-02-20 1992-02-14 Neuro-schützende mittel.

Country Status (15)

Country Link
US (1) US5508401A (de)
EP (1) EP0573548B1 (de)
JP (1) JPH06505737A (de)
KR (1) KR100199913B1 (de)
AT (1) ATE124946T1 (de)
AU (1) AU662730B2 (de)
CA (1) CA2101933A1 (de)
DE (1) DE69203445T2 (de)
DK (1) DK0573548T3 (de)
ES (1) ES2074884T3 (de)
GR (1) GR3017663T3 (de)
IE (1) IE69124B1 (de)
NZ (1) NZ241635A (de)
PT (1) PT100133B (de)
WO (1) WO1992014813A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992019621A1 (en) * 1991-04-29 1992-11-12 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene, Oregon Pcp receptor ligands and the use thereof
JP2933554B2 (ja) * 1996-11-28 1999-08-16 九州日本電気株式会社 半導体装置およびその製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3361767A (en) * 1966-04-04 1968-01-02 American Home Prod 10, 5(epoxymethano)-10, 11-dihydro-5h-dibenzo[a, d]cyclohepten-13-one and derivatives
US3597433A (en) * 1968-08-19 1971-08-03 Ayerst Mckenna & Harrison 10,11 - dihydro - 5,10 - (iminomethano)-5h-dibenzo(a,d)cycloheptene and derivatives thereof
US5011834A (en) * 1989-04-14 1991-04-30 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon PCP receptor ligands and the use thereof
US4940789A (en) * 1989-10-10 1990-07-10 American Home Products Corporation 10,11-dihydro-5-alkyl-12-substituted-10,5-(iminomethano)-5H-dibenzo[a,d]cycloheptenes as neuroprotectant agents
WO1992019621A1 (en) * 1991-04-29 1992-11-12 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene, Oregon Pcp receptor ligands and the use thereof

Also Published As

Publication number Publication date
KR100199913B1 (ko) 1999-06-15
AU1443092A (en) 1992-09-15
DE69203445D1 (de) 1995-08-17
IE69124B1 (en) 1996-08-07
US5508401A (en) 1996-04-16
AU662730B2 (en) 1995-09-14
EP0573548B1 (de) 1995-07-12
DE69203445T2 (de) 1995-11-23
GR3017663T3 (en) 1996-01-31
NZ241635A (en) 1993-10-26
JPH06505737A (ja) 1994-06-30
EP0573548A1 (de) 1993-12-15
KR930703318A (ko) 1993-11-29
WO1992014813A1 (en) 1992-09-03
IE920513A1 (en) 1992-08-26
DK0573548T3 (da) 1995-11-13
CA2101933A1 (en) 1992-08-21
PT100133B (pt) 1999-06-30
PT100133A (pt) 1993-05-31
ES2074884T3 (es) 1995-09-16

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee