ATE125870T1 - Hiv-spezifische monoklonale antikörper und hybridome zu ihrer herstellung. - Google Patents

Hiv-spezifische monoklonale antikörper und hybridome zu ihrer herstellung.

Info

Publication number
ATE125870T1
ATE125870T1 AT88403036T AT88403036T ATE125870T1 AT E125870 T1 ATE125870 T1 AT E125870T1 AT 88403036 T AT88403036 T AT 88403036T AT 88403036 T AT88403036 T AT 88403036T AT E125870 T1 ATE125870 T1 AT E125870T1
Authority
AT
Austria
Prior art keywords
monoclonal antibodies
hiv
hybridomas
production
specific monoclonal
Prior art date
Application number
AT88403036T
Other languages
English (en)
Inventor
Yasuhiko Masuho
Toru Sugano
Yoh-Ichi Matsumoto
Evan Hersh
Eskild Petersen
Douglas Arizona Health Sc Lake
Medicine
Original Assignee
Univ Arizona
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Arizona, Teijin Ltd filed Critical Univ Arizona
Application granted granted Critical
Publication of ATE125870T1 publication Critical patent/ATE125870T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10RNA viruses
    • C07K16/112Retroviridae (F), e.g. leukemia viruses
    • C07K16/114Lentivirus (G), e.g. human immunodeficiency virus [HIV], feline immunodeficiency virus [FIV] or simian immunodeficiency virus [SIV]
    • C07K16/1145Env proteins, e.g. gp41, gp110/120, gp160, V3, principal neutralising domain [PND] or CD4-binding site
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • C12N5/12Fused cells, e.g. hybridomas
    • C12N5/16Animal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT88403036T 1988-03-31 1988-12-01 Hiv-spezifische monoklonale antikörper und hybridome zu ihrer herstellung. ATE125870T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/176,159 US5298419A (en) 1988-03-31 1988-03-31 Human hybridomas and monoclonal antibodies which bind both gp41 and gp120 envelope proteins of human immunodeficiency virus

Publications (1)

Publication Number Publication Date
ATE125870T1 true ATE125870T1 (de) 1995-08-15

Family

ID=22643233

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88403036T ATE125870T1 (de) 1988-03-31 1988-12-01 Hiv-spezifische monoklonale antikörper und hybridome zu ihrer herstellung.

Country Status (8)

Country Link
US (1) US5298419A (de)
EP (1) EP0339163B1 (de)
JP (2) JPH0753755B2 (de)
KR (1) KR0149848B1 (de)
AT (1) ATE125870T1 (de)
AU (1) AU627698B2 (de)
CA (1) CA1339858C (de)
DE (1) DE3854267T2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU9072991A (en) * 1990-10-26 1992-05-26 Public Health Research Institute Of The City Of New York, Inc., The Neutralizing human monoclonal antibodies specific for the v3 loop and cd-4 binding site of hiv-1 gp120
US6030804A (en) * 1995-06-06 2000-02-29 Human Genome Sciences, Inc. Polynucleotides encoding G-protein parathyroid hormone receptor HLTDG74 polypeptides
US6197582B1 (en) 1998-03-18 2001-03-06 The Trustees Of Columbia University In The City Of New York Development of human monoclonal antibodies and uses thereof
US7115262B1 (en) 1999-03-16 2006-10-03 The United States Of America As Represented By The Department Of Health And Human Services Chimeric protein for prevention and treatment of HIV infection
US7060802B1 (en) * 2000-09-18 2006-06-13 The Trustees Of Columbia University In The City Of New York Tumor-associated marker
JP4277490B2 (ja) * 2001-08-27 2009-06-10 セイコーエプソン株式会社 マイクロカプセル化顔料及びその製造方法、水性分散液、並びに、インクジェット記録用インク
AU2006220712A1 (en) * 2005-03-07 2006-09-14 Albert Einstein College Of Medicine Of Yeshiva University Methods of applying ionization radiation for therapy of HIV infection
CA2623197A1 (en) * 2005-09-22 2007-03-29 Prosci Incorporated Glycosylated polypeptides produced in yeast mutants and methods of use thereof
CA2767063A1 (en) * 2009-07-03 2011-01-06 Bionor Immuno As Novel therapeutic and diagnostic means
WO2017093985A1 (en) 2015-12-05 2017-06-08 Centre Hospitalier Universitaire Vaudois Hiv binding agents
WO2020012435A1 (en) 2018-07-13 2020-01-16 Lausanne University Hospital Hiv binding agents
JP7678790B2 (ja) 2019-07-15 2025-05-16 ローザンヌ ユニヴァーシティ ホスピタル Hiv結合剤

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5536337Y2 (de) * 1976-03-29 1980-08-27
US4515894A (en) * 1979-03-20 1985-05-07 Ortho Pharmaceutical Corporation Hybrid cell line for producing monoclonal antibody to human T cells
US4363799A (en) * 1979-03-20 1982-12-14 Ortho Pharmaceutical Corporation Monoclonal antibody to human T cells, and methods for preparing same
US5087557A (en) * 1986-06-23 1992-02-11 Genetic Systems Corporation Human monoclonal antibody to lymphadenopathy-associated virus
IE63109B1 (en) * 1986-06-23 1995-03-22 Genetic Systems Corp Human monoclonal antibody to lymphadenopathy-associated virus
JPS6349316U (de) * 1986-09-17 1988-04-04
JPS63105619U (de) * 1986-12-26 1988-07-08

Also Published As

Publication number Publication date
KR0149848B1 (ko) 1999-03-30
JPH0753755B2 (ja) 1995-06-07
JPH07292000A (ja) 1995-11-07
AU2456888A (en) 1989-10-05
DE3854267D1 (de) 1995-09-07
KR890014730A (ko) 1989-10-25
US5298419A (en) 1994-03-29
AU627698B2 (en) 1992-09-03
DE3854267T2 (de) 1996-01-04
EP0339163A3 (en) 1990-05-09
JPH02219592A (ja) 1990-09-03
EP0339163A2 (de) 1989-11-02
CA1339858C (en) 1998-05-05
EP0339163B1 (de) 1995-08-02

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee