ATE126190T1 - 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-5- - Google Patents

1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-5-

Info

Publication number
ATE126190T1
ATE126190T1 AT90123907T AT90123907T ATE126190T1 AT E126190 T1 ATE126190 T1 AT E126190T1 AT 90123907 T AT90123907 T AT 90123907T AT 90123907 T AT90123907 T AT 90123907T AT E126190 T1 ATE126190 T1 AT E126190T1
Authority
AT
Austria
Prior art keywords
nitrophenyl
dihydro
dimethyl
compounds
disclosed
Prior art date
Application number
AT90123907T
Other languages
English (en)
Inventor
John P Carter
Waclaw J Rzeszotarski
Original Assignee
Marion Merrell Dow Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marion Merrell Dow Inc filed Critical Marion Merrell Dow Inc
Application granted granted Critical
Publication of ATE126190T1 publication Critical patent/ATE126190T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
AT90123907T 1989-12-14 1990-12-12 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-5- ATE126190T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/450,736 US4975437A (en) 1989-12-14 1989-12-14 Isomers of 1-azabicyclo(2.2.2)oct-3-yl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-5-nitropyridine-3-carboxylate

Publications (1)

Publication Number Publication Date
ATE126190T1 true ATE126190T1 (de) 1995-08-15

Family

ID=23789296

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90123907T ATE126190T1 (de) 1989-12-14 1990-12-12 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-5-

Country Status (8)

Country Link
US (1) US4975437A (de)
EP (1) EP0432751B1 (de)
JP (1) JP3029051B2 (de)
AT (1) ATE126190T1 (de)
AU (1) AU633386B2 (de)
CA (1) CA2031937C (de)
DE (1) DE69021518T2 (de)
ES (1) ES2078288T3 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1230881B (it) * 1989-06-20 1991-11-08 Angeli Inst Spa Derivati del r(-) 3-chinuclidinolo
JP2007530664A (ja) * 2004-03-30 2007-11-01 ペインセプター ファーマ コーポレーション ゲートイオンチャンネルを調節するための組成物及び方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines

Also Published As

Publication number Publication date
EP0432751B1 (de) 1995-08-09
EP0432751A2 (de) 1991-06-19
CA2031937C (en) 2001-05-22
EP0432751A3 (en) 1992-02-12
JP3029051B2 (ja) 2000-04-04
DE69021518D1 (de) 1995-09-14
JPH04270279A (ja) 1992-09-25
AU6791690A (en) 1991-06-20
AU633386B2 (en) 1993-01-28
DE69021518T2 (de) 1996-01-04
US4975437A (en) 1990-12-04
ES2078288T3 (es) 1995-12-16
CA2031937A1 (en) 1991-06-15

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee