ATE126190T1 - 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-5- - Google Patents

1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-5-

Info

Publication number: ATE126190T1
Authority: AT; Austria
Prior art keywords: nitrophenyl; dihydro; dimethyl; compounds; disclosed
Prior art date: 1989-12-14

Application number

AT90123907T

Other languages

English (en)

Inventor

John P Carter

Waclaw J Rzeszotarski

Original Assignee

Marion Merrell Dow Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-12-14

Filing date

1990-12-12

Publication date

1995-08-15

1990-12-12 Application filed by Marion Merrell Dow Inc filed Critical Marion Merrell Dow Inc

1995-08-15 Application granted granted Critical

1995-08-15 Publication of ATE126190T1 publication Critical patent/ATE126190T1/de

Links

150000001875 compounds Chemical class 0.000 abstract 2
MMWRGWQTAMNAFC-UHFFFAOYSA-N 1,2-dihydropyridine Chemical class C1NC=CC=C1 MMWRGWQTAMNAFC-UHFFFAOYSA-N 0.000 abstract 1
150000001298 alcohols Chemical class 0.000 abstract 1
230000003177 cardiotonic effect Effects 0.000 abstract 1
239000003937 drug carrier Substances 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Hydrogenated Pyridines (AREA)

AT90123907T 1989-12-14 1990-12-12 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-5- ATE126190T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/450,736 US4975437A (en)	1989-12-14	1989-12-14	Isomers of 1-azabicyclo(2.2.2)oct-3-yl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-5-nitropyridine-3-carboxylate

Publications (1)

Publication Number	Publication Date
ATE126190T1 true ATE126190T1 (de)	1995-08-15

Family

ID=23789296

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90123907T ATE126190T1 (de)	1989-12-14	1990-12-12	1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-5-

Country Status (8)

Country	Link
US (1)	US4975437A (de)
EP (1)	EP0432751B1 (de)
JP (1)	JP3029051B2 (de)
AT (1)	ATE126190T1 (de)
AU (1)	AU633386B2 (de)
CA (1)	CA2031937C (de)
DE (1)	DE69021518T2 (de)
ES (1)	ES2078288T3 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1230881B (it) *	1989-06-20	1991-11-08	Angeli Inst Spa	Derivati del r(-) 3-chinuclidinolo
EP1734962A4 (de) *	2004-03-30	2010-07-14	Painceptor Pharma Corp	Zusammensetzungen und verfahren zur modulierung von gesteuerten ionenkanälen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ201395A (en) *	1981-07-30	1987-02-20	Bayer Ag	Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines

1989
- 1989-12-14 US US07/450,736 patent/US4975437A/en not_active Expired - Fee Related
1990
- 1990-12-10 AU AU67916/90A patent/AU633386B2/en not_active Ceased
- 1990-12-11 CA CA002031937A patent/CA2031937C/en not_active Expired - Fee Related
- 1990-12-12 EP EP90123907A patent/EP0432751B1/de not_active Expired - Lifetime
- 1990-12-12 ES ES90123907T patent/ES2078288T3/es not_active Expired - Lifetime
- 1990-12-12 DE DE69021518T patent/DE69021518T2/de not_active Expired - Fee Related
- 1990-12-12 AT AT90123907T patent/ATE126190T1/de not_active IP Right Cessation
- 1990-12-13 JP JP2410131A patent/JP3029051B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JP3029051B2 (ja)	2000-04-04
US4975437A (en)	1990-12-04
CA2031937C (en)	2001-05-22
EP0432751A2 (de)	1991-06-19
AU633386B2 (en)	1993-01-28
AU6791690A (en)	1991-06-20
JPH04270279A (ja)	1992-09-25
DE69021518T2 (de)	1996-01-04
EP0432751B1 (de)	1995-08-09
ES2078288T3 (es)	1995-12-16
CA2031937A1 (en)	1991-06-15
EP0432751A3 (en)	1992-02-12
DE69021518D1 (de)	1995-09-14

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Legal Events

Date	Code	Title	Description
1996-03-15	UEP	Publication of translation of european patent specification
2004-09-15	REN	Ceased due to non-payment of the annual fee