ATE127028T1 - Einpflanzbares iontophoretisches abgabesystem. - Google Patents

Einpflanzbares iontophoretisches abgabesystem.

Info

Publication number
ATE127028T1
ATE127028T1 AT91305522T AT91305522T ATE127028T1 AT E127028 T1 ATE127028 T1 AT E127028T1 AT 91305522 T AT91305522 T AT 91305522T AT 91305522 T AT91305522 T AT 91305522T AT E127028 T1 ATE127028 T1 AT E127028T1
Authority
AT
Austria
Prior art keywords
interest
delivery system
iontophoretic delivery
pouch
conjunction
Prior art date
Application number
AT91305522T
Other languages
English (en)
Inventor
Boaz Avitall
Original Assignee
Boaz Avitall
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boaz Avitall filed Critical Boaz Avitall
Application granted granted Critical
Publication of ATE127028T1 publication Critical patent/ATE127028T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/38—Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
    • A61N1/39—Heart defibrillators
    • A61N1/3956—Implantable devices for applying electric shocks to the heart, e.g. for cardioversion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A61N1/306—Arrangements where at least part of the apparatus is introduced into the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Electrotherapy Devices (AREA)
  • Materials For Medical Uses (AREA)
AT91305522T 1990-06-18 1991-06-18 Einpflanzbares iontophoretisches abgabesystem. ATE127028T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/539,611 US5087243A (en) 1990-06-18 1990-06-18 Myocardial iontophoresis

Publications (1)

Publication Number Publication Date
ATE127028T1 true ATE127028T1 (de) 1995-09-15

Family

ID=24151938

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91305522T ATE127028T1 (de) 1990-06-18 1991-06-18 Einpflanzbares iontophoretisches abgabesystem.

Country Status (6)

Country Link
US (1) US5087243A (de)
EP (1) EP0468636B1 (de)
JP (1) JP2686383B2 (de)
AT (1) ATE127028T1 (de)
CA (1) CA2044791C (de)
DE (1) DE69112533T2 (de)

Families Citing this family (229)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5499971A (en) * 1990-06-15 1996-03-19 Cortrak Medical, Inc. Method for iontophoretically delivering drug adjacent to a heart
EP0533816B1 (de) * 1990-06-15 1995-06-14 Cortrak Medical, Inc. Vorrichtung zur abgabe von medikamenten
US5498238A (en) * 1990-06-15 1996-03-12 Cortrak Medical, Inc. Simultaneous angioplasty and phoretic drug delivery
US5405362A (en) * 1991-04-29 1995-04-11 The Board Of Regents For The University Of Texas System Interactive external defibrillation and drug injection system
US5458568A (en) * 1991-05-24 1995-10-17 Cortrak Medical, Inc. Porous balloon for selective dilatation and drug delivery
SE9102778D0 (sv) * 1991-09-25 1991-09-25 Siemens Elema Ab Implanterbar medicinsk anordning
US5313953A (en) * 1992-01-14 1994-05-24 Incontrol, Inc. Implantable cardiac patient monitor
US6132419A (en) * 1992-05-22 2000-10-17 Genetronics, Inc. Electroporetic gene and drug therapy
US5501662A (en) * 1992-05-22 1996-03-26 Genetronics, Inc. Implantable electroporation method and apparatus for drug and gene delivery
US5634899A (en) * 1993-08-20 1997-06-03 Cortrak Medical, Inc. Simultaneous cardiac pacing and local drug delivery method
US5807306A (en) * 1992-11-09 1998-09-15 Cortrak Medical, Inc. Polymer matrix drug delivery apparatus
EP0644756A4 (de) * 1993-03-15 1996-02-28 Univ Michigan System zur kontrollierten freisetzung von antiarrhythmischen wirkstoffen.
US5464447A (en) * 1994-01-28 1995-11-07 Sony Corporation Implantable defibrillator electrodes
US6853859B1 (en) * 1994-05-31 2005-02-08 Galvani, Ltd. Electrical cardiac output forcer
US5925066A (en) * 1995-10-26 1999-07-20 Galvani, Ltd. Atrial arrythmia sensor with drug and electrical therapy control apparatus
US6185457B1 (en) * 1994-05-31 2001-02-06 Galvani, Ltd. Method and apparatus for electrically forcing cardiac output in an arrhythmia patient
US5505700A (en) * 1994-06-14 1996-04-09 Cordis Corporation Electro-osmotic infusion catheter
US5728068A (en) * 1994-06-14 1998-03-17 Cordis Corporation Multi-purpose balloon catheter
US5662689A (en) * 1995-09-08 1997-09-02 Medtronic, Inc. Method and apparatus for alleviating cardioversion shock pain
US8321013B2 (en) 1996-01-08 2012-11-27 Impulse Dynamics, N.V. Electrical muscle controller and pacing with hemodynamic enhancement
US9289618B1 (en) 1996-01-08 2016-03-22 Impulse Dynamics Nv Electrical muscle controller
IL125424A0 (en) 1998-07-20 1999-03-12 New Technologies Sa Ysy Ltd Pacing with hemodynamic enhancement
US8825152B2 (en) * 1996-01-08 2014-09-02 Impulse Dynamics, N.V. Modulation of intracellular calcium concentration using non-excitatory electrical signals applied to the tissue
US7167748B2 (en) * 1996-01-08 2007-01-23 Impulse Dynamics Nv Electrical muscle controller
US6317631B1 (en) * 1996-01-08 2001-11-13 Impulse Dynamics N.V. Controlling heart performance using a non-excitatory electric field
US9713723B2 (en) 1996-01-11 2017-07-25 Impulse Dynamics Nv Signal delivery through the right ventricular septum
US5697951A (en) * 1996-04-25 1997-12-16 Medtronic, Inc. Implantable stimulation and drug infusion techniques
AU2437397A (en) 1996-07-17 1998-02-09 Medtronic, Inc. System for enhancing cardiac signal sensing by cardiac pacemakers through genetic treatment
US5709653A (en) * 1996-07-25 1998-01-20 Cordis Corporation Photodynamic therapy balloon catheter with microporous membrane
US5797868A (en) * 1996-07-25 1998-08-25 Cordis Corporation Photodynamic therapy balloon catheter
US5720775A (en) * 1996-07-31 1998-02-24 Cordis Corporation Percutaneous atrial line ablation catheter
US7840264B1 (en) 1996-08-19 2010-11-23 Mr3 Medical, Llc System and method for breaking reentry circuits by cooling cardiac tissue
US7908003B1 (en) 1996-08-19 2011-03-15 Mr3 Medical Llc System and method for treating ischemia by improving cardiac efficiency
US5702343A (en) * 1996-10-02 1997-12-30 Acorn Medical, Inc. Cardiac reinforcement device
US6123662A (en) * 1998-07-13 2000-09-26 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US5800464A (en) * 1996-10-03 1998-09-01 Medtronic, Inc. System for providing hyperpolarization of cardiac to enhance cardiac function
US5814079A (en) * 1996-10-04 1998-09-29 Medtronic, Inc. Cardiac arrhythmia management by application of adnodal stimulation for hyperpolarization of myocardial cells
US7033598B2 (en) * 1996-11-19 2006-04-25 Intrabrain International N.V. Methods and apparatus for enhanced and controlled delivery of a biologically active agent into the central nervous system of a mammal
US6913763B2 (en) * 1996-11-19 2005-07-05 Intrabrain International Nv Method and device for enhanced delivery of a biologically active agent through the spinal spaces into the central nervous system of a mammal
WO1998058598A1 (de) 1997-06-21 1998-12-30 Hans Haindl Beutel zur wenigstens teilweisen umfassung eines herzens
ATE353689T1 (de) 1997-07-16 2007-03-15 Metacure Nv Einrichtung zur steuerung eines glatten muskels
US6096037A (en) 1997-07-29 2000-08-01 Medtronic, Inc. Tissue sealing electrosurgery device and methods of sealing tissue
US6711436B1 (en) 1997-08-08 2004-03-23 Duke University Compositions, apparatus and methods for facilitating surgical procedures
DE69833665T2 (de) 1997-08-08 2006-11-09 Duke University Zusammensetzungen zur vereinfachung von chirurgischen verfahren
US6592552B1 (en) 1997-09-19 2003-07-15 Cecil C. Schmidt Direct pericardial access device and method
US5972013A (en) * 1997-09-19 1999-10-26 Comedicus Incorporated Direct pericardial access device with deflecting mechanism and method
US6251418B1 (en) 1997-12-18 2001-06-26 C.R. Bard, Inc. Systems and methods for local delivery of an agent
US6197324B1 (en) 1997-12-18 2001-03-06 C. R. Bard, Inc. System and methods for local delivery of an agent
US6231518B1 (en) 1998-05-26 2001-05-15 Comedicus Incorporated Intrapericardial electrophysiological procedures
US6085754A (en) 1998-07-13 2000-07-11 Acorn Cardiovascular, Inc. Cardiac disease treatment method
US6689121B1 (en) 1998-09-24 2004-02-10 C. R. Bard, Inc. Systems and methods for treating ischemia
US6248112B1 (en) 1998-09-30 2001-06-19 C. R. Bard, Inc. Implant delivery system
US6432126B1 (en) * 1998-09-30 2002-08-13 C.R. Bard, Inc. Flexible vascular inducing implants
US6458092B1 (en) 1998-09-30 2002-10-01 C. R. Bard, Inc. Vascular inducing implants
US6587734B2 (en) * 1998-11-04 2003-07-01 Acorn Cardiovascular, Inc. Cardio therapeutic heart sack
US6230714B1 (en) 1998-11-18 2001-05-15 Acorn Cardiovascular, Inc. Cardiac constraint with prior venus occlusion methods
US6169922B1 (en) 1998-11-18 2001-01-02 Acorn Cardiovascular, Inc. Defibrillating cardiac jacket with interwoven electrode grids
US6692520B1 (en) 1998-12-15 2004-02-17 C. R. Bard, Inc. Systems and methods for imbedded intramuscular implants
US6155972A (en) * 1999-02-02 2000-12-05 Acorn Cardiovascular, Inc. Cardiac constraint jacket construction
MXPA01007820A (es) * 1999-02-04 2003-06-19 Technion Res & Dev Foundation Metodo y aparato para mantenimiento y expansion de celulas de tallo hemopoyeticas y/o celulas progenitoras.
US20040249421A1 (en) * 2000-09-13 2004-12-09 Impulse Dynamics Nv Blood glucose level control
US8666495B2 (en) * 1999-03-05 2014-03-04 Metacure Limited Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar
US8346363B2 (en) * 1999-03-05 2013-01-01 Metacure Limited Blood glucose level control
US8019421B2 (en) * 1999-03-05 2011-09-13 Metacure Limited Blood glucose level control
WO2006073671A1 (en) * 2004-12-09 2006-07-13 Impulse Dynamics Nv Protein activity modification
US8700161B2 (en) * 1999-03-05 2014-04-15 Metacure Limited Blood glucose level control
US9101765B2 (en) 1999-03-05 2015-08-11 Metacure Limited Non-immediate effects of therapy
WO2000053256A1 (en) 1999-03-08 2000-09-14 Palti Yoram Prof Transdermal drug delivery system and method
US6986784B1 (en) 1999-05-14 2006-01-17 C. R. Bard, Inc. Implant anchor systems
US7092753B2 (en) * 1999-06-04 2006-08-15 Impulse Dynamics Nv Drug delivery device
US7190997B1 (en) 1999-06-04 2007-03-13 Impulse Dynamics Nv Drug delivery device
WO2000074773A1 (en) 1999-06-04 2000-12-14 Impulse Dynamics N.V. Drug delivery device
US7171263B2 (en) * 1999-06-04 2007-01-30 Impulse Dynamics Nv Drug delivery device
US6241654B1 (en) 1999-07-07 2001-06-05 Acorn Cardiovasculr, Inc. Cardiac reinforcement devices and methods
US6855160B1 (en) 1999-08-04 2005-02-15 C. R. Bard, Inc. Implant and agent delivery device
US6282444B1 (en) * 1999-08-31 2001-08-28 Pacesetter, Inc. Implantable device with electrical infection control
US6174279B1 (en) 1999-09-21 2001-01-16 Acorn Cardiovascular, Inc. Cardiac constraint with tension indicator
US6179791B1 (en) 1999-09-21 2001-01-30 Acorn Cardiovascular, Inc. Device for heart measurement
US6193648B1 (en) 1999-09-21 2001-02-27 Acorn Cardiovascular, Inc. Cardiac constraint with draw string tensioning
US6587718B2 (en) * 1999-10-08 2003-07-01 Scimed Life Systems, Inc. Iontophoretic delivery to heart tissue
US6361522B1 (en) 1999-10-21 2002-03-26 Cardiac Pacemakers, Inc. Drug delivery system for implantable cardiac device
US6993385B1 (en) * 1999-10-25 2006-01-31 Impulse Dynamics N.V. Cardiac contractility modulation device having anti-arrhythmic capabilities and a method of operating thereof
WO2001030445A1 (en) 1999-10-25 2001-05-03 Impulse Dynamics N.V. Cardiac contractility modulation device having anti-arrhythmic capabilities and a method of operating thereof
US7027863B1 (en) 1999-10-25 2006-04-11 Impulse Dynamics N.V. Device for cardiac therapy
US6702732B1 (en) 1999-12-22 2004-03-09 Paracor Surgical, Inc. Expandable cardiac harness for treating congestive heart failure
US6293906B1 (en) * 2000-01-14 2001-09-25 Acorn Cardiovascular, Inc. Delivery of cardiac constraint jacket
US6447443B1 (en) * 2001-01-13 2002-09-10 Medtronic, Inc. Method for organ positioning and stabilization
CA2400074A1 (en) 2000-02-18 2001-08-23 William I. Higuchi Methods for extracting substances using alternating current
EP1259285A1 (de) 2000-02-18 2002-11-27 University of Utah Verfahren zur abreichung von medikamenten durch wechselstrom
US6810286B2 (en) * 2000-03-06 2004-10-26 Medtronic, Inc Stimulation for delivery of molecular therapy
EP1261294B1 (de) * 2000-03-10 2006-11-29 Paracor Medical, Inc. Expandierbarer herzbeutel zur behandlung von kongestiven herzversagens
US6905498B2 (en) 2000-04-27 2005-06-14 Atricure Inc. Transmural ablation device with EKG sensor and pacing electrode
US20020107514A1 (en) * 2000-04-27 2002-08-08 Hooven Michael D. Transmural ablation device with parallel jaws
US6932811B2 (en) 2000-04-27 2005-08-23 Atricure, Inc. Transmural ablation device with integral EKG sensor
US6546935B2 (en) 2000-04-27 2003-04-15 Atricure, Inc. Method for transmural ablation
WO2001085027A2 (en) * 2000-05-08 2001-11-15 Image-Guided Neurologics, Inc. Drug deliver catheter device with active electrode
US6549803B1 (en) 2000-05-08 2003-04-15 Image-Guided Neurologics Inc. Method and apparatus for targeting material delivery to tissue
US6425856B1 (en) 2000-05-10 2002-07-30 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US7232421B1 (en) 2000-05-12 2007-06-19 C. R. Bard, Inc. Agent delivery systems
US6730016B1 (en) * 2000-06-12 2004-05-04 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US20050095268A1 (en) * 2000-06-12 2005-05-05 Acorn Cardiovascular, Inc. Cardiac wall tension relief with cell loss management
US6902522B1 (en) 2000-06-12 2005-06-07 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US6482146B1 (en) 2000-06-13 2002-11-19 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US6951534B2 (en) * 2000-06-13 2005-10-04 Acorn Cardiovascular, Inc. Cardiac support device
US7204847B1 (en) 2000-07-28 2007-04-17 C. R. Bard, Inc. Implant anchor systems
US6572533B1 (en) * 2000-08-17 2003-06-03 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US6726920B1 (en) * 2000-09-22 2004-04-27 Durect Corporation Implantable drug delivery patch
US7369890B2 (en) * 2000-11-02 2008-05-06 Cardiac Pacemakers, Inc. Technique for discriminating between coordinated and uncoordinated cardiac rhythms
US6689117B2 (en) 2000-12-18 2004-02-10 Cardiac Pacemakers, Inc. Drug delivery system for implantable medical device
US6564094B2 (en) 2000-12-22 2003-05-13 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US7130682B2 (en) 2000-12-26 2006-10-31 Cardiac Pacemakers, Inc. Pacing and sensing vectors
US7740623B2 (en) * 2001-01-13 2010-06-22 Medtronic, Inc. Devices and methods for interstitial injection of biologic agents into tissue
US7628780B2 (en) * 2001-01-13 2009-12-08 Medtronic, Inc. Devices and methods for interstitial injection of biologic agents into tissue
US20040138621A1 (en) * 2003-01-14 2004-07-15 Jahns Scott E. Devices and methods for interstitial injection of biologic agents into tissue
US6575921B2 (en) 2001-02-09 2003-06-10 Acorn Cardiovascular, Inc. Device for heart measurement
US7137975B2 (en) 2001-02-13 2006-11-21 Aciont, Inc. Method for increasing the battery life of an alternating current iontophoresis device using a barrier-modifying agent
US6453195B1 (en) 2001-03-19 2002-09-17 Medtronic, Inc. Closed loop drug delivery system and remote management thereof
US20020188327A1 (en) * 2001-04-26 2002-12-12 Chester Struble Drug delivery for treatment of cardiac arrhythmia
US7493162B2 (en) * 2001-06-15 2009-02-17 Cardiac Pacemakers, Inc. Pulmonary vein stent for treating atrial fibrillation
US7209783B2 (en) * 2001-06-15 2007-04-24 Cardiac Pacemakers, Inc. Ablation stent for treating atrial fibrillation
US20040236377A1 (en) * 2001-07-02 2004-11-25 Medtronic, Inc. System and method for enhancing cardiac signal sensing by cardiac pacemakers through genetic treatment
US6716158B2 (en) 2001-09-07 2004-04-06 Mardil, Inc. Method and apparatus for external stabilization of the heart
JP2005501652A (ja) * 2001-09-10 2005-01-20 パラコー メディカル インコーポレイテッド 心不全治療用装置
US7340303B2 (en) * 2001-09-25 2008-03-04 Cardiac Pacemakers, Inc. Evoked response sensing for ischemia detection
US20070088335A1 (en) * 2001-10-24 2007-04-19 Med-El Elektromedizinische Geraete Gmbh Implantable neuro-stimulation electrode with fluid reservoir
WO2003034960A1 (en) * 2001-10-24 2003-05-01 Med-El Elektromedizinische Geräte Ges.m.b.H. Implantable fluid delivery apparatuses and implantable electrode
WO2003037217A1 (en) * 2001-10-31 2003-05-08 Paracor Medical, Inc. Heart failure treatment device
WO2003039344A2 (en) * 2001-11-08 2003-05-15 The Regents Of The University Of California Methods and compositions for correction of cardiac conduction disturbances
US7022063B2 (en) 2002-01-07 2006-04-04 Paracor Medical, Inc. Cardiac harness
US7174896B1 (en) 2002-01-07 2007-02-13 Paracor Medical, Inc. Method and apparatus for supporting a heart
US7967816B2 (en) 2002-01-25 2011-06-28 Medtronic, Inc. Fluid-assisted electrosurgical instrument with shapeable electrode
US6968226B2 (en) * 2002-01-30 2005-11-22 Medtronic, Inc. Method and system for terminating an atrial arrhythmia
US7236821B2 (en) * 2002-02-19 2007-06-26 Cardiac Pacemakers, Inc. Chronically-implanted device for sensing and therapy
US7110815B2 (en) * 2002-05-06 2006-09-19 Cardiac Pacemakers, Inc. System and method for providing temporary stimulation therapy to optimize chronic electrical performance for electrodes used in conjunction with a cardiac rhythm management system
AU2003234520A1 (en) * 2002-05-08 2003-11-11 The Regents Of The University Of California Methods and compositions for correction of cardiac conduction disturbances
AU2003237824B9 (en) * 2002-05-08 2008-06-19 The Regents Of The University Of California System and method for treating cardiac arrhythmias with fibroblast cells
EP1503819A4 (de) * 2002-05-08 2007-07-25 Univ California System und verfahren zur herstellung eines nichtablativen herzleitungsblocks
US20040106896A1 (en) * 2002-11-29 2004-06-03 The Regents Of The University Of California System and method for forming a non-ablative cardiac conduction block
US20030229260A1 (en) * 2002-06-05 2003-12-11 Acorn Cardiovascular, Inc. Cardiac support device with tension indicator
US20030229261A1 (en) * 2002-06-06 2003-12-11 Acorn Cardiovascular, Inc. Cardiac support devices and methods of producing same
US6682475B2 (en) 2002-06-11 2004-01-27 Acorn Cardiovascular, Inc. Tension indicator for cardiac support device and method therefore
US7089055B2 (en) * 2002-06-28 2006-08-08 Cardiac Pacemakers, Inc. Method and apparatus for delivering pre-shock defibrillation therapy
CA2496229A1 (en) * 2002-09-05 2004-03-18 Paracor Medical, Inc. Cardiac harness
US7139613B2 (en) * 2002-09-25 2006-11-21 Medtronic, Inc. Implantable medical device communication system with pulsed power biasing
US7013178B2 (en) * 2002-09-25 2006-03-14 Medtronic, Inc. Implantable medical device communication system
US7291161B2 (en) 2002-10-02 2007-11-06 Atricure, Inc. Articulated clamping member
US7072711B2 (en) 2002-11-12 2006-07-04 Cardiac Pacemakers, Inc. Implantable device for delivering cardiac drug therapy
US20050059855A1 (en) * 2002-11-15 2005-03-17 Lilip Lau Cardiac harness delivery device and method
US7736299B2 (en) * 2002-11-15 2010-06-15 Paracor Medical, Inc. Introducer for a cardiac harness delivery
US20070255093A1 (en) * 2002-11-15 2007-11-01 Lilip Lau Cardiac harness delivery device and method
US7229405B2 (en) 2002-11-15 2007-06-12 Paracor Medical, Inc. Cardiac harness delivery device and method of use
EP1560541A2 (de) * 2002-11-15 2005-08-10 Paracor Medical, Inc. Herzbeutelanbringungssystem
US20040158289A1 (en) * 2002-11-30 2004-08-12 Girouard Steven D. Method and apparatus for cell and electrical therapy of living tissue
US7627373B2 (en) * 2002-11-30 2009-12-01 Cardiac Pacemakers, Inc. Method and apparatus for cell and electrical therapy of living tissue
WO2004070396A2 (en) * 2003-02-10 2004-08-19 N-Trig Ltd. Touch detection for a digitizer
US8290579B2 (en) * 2003-02-19 2012-10-16 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Device, methods and sponges for iontophoretic drug delivery
US11439815B2 (en) 2003-03-10 2022-09-13 Impulse Dynamics Nv Protein activity modification
US7840262B2 (en) * 2003-03-10 2010-11-23 Impulse Dynamics Nv Apparatus and method for delivering electrical signals to modify gene expression in cardiac tissue
US20050283042A1 (en) * 2003-03-28 2005-12-22 Steve Meyer Cardiac harness having radiopaque coating and method of use
US20040249242A1 (en) * 2003-03-28 2004-12-09 Lilip Lau Multi-panel cardiac harness
US7288092B2 (en) 2003-04-23 2007-10-30 Atricure, Inc. Method and apparatus for ablating cardiac tissue with guide facility
WO2005007032A2 (en) * 2003-07-10 2005-01-27 Paracor Medical, Inc. Self-anchoring cardiac harness
US8792985B2 (en) * 2003-07-21 2014-07-29 Metacure Limited Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar
US7320675B2 (en) 2003-08-21 2008-01-22 Cardiac Pacemakers, Inc. Method and apparatus for modulating cellular metabolism during post-ischemia or heart failure
US7742809B2 (en) * 2003-08-25 2010-06-22 Medtronic, Inc. Electroporation catheter with sensing capabilities
US7235042B2 (en) * 2003-09-16 2007-06-26 Acorn Cardiovascular, Inc. Apparatus and method for applying cardiac support device
US20070055091A1 (en) * 2004-12-02 2007-03-08 Lilip Lau Cardiac harness for treating congestive heart failure and for defibrillating and/or pacing/sensing
US20070106359A1 (en) * 2003-11-07 2007-05-10 Alan Schaer Cardiac harness assembly for treating congestive heart failure and for pacing/sensing
US7158839B2 (en) * 2003-11-07 2007-01-02 Paracor Medical, Inc. Cardiac harness for treating heart disease
US7155295B2 (en) 2003-11-07 2006-12-26 Paracor Medical, Inc. Cardiac harness for treating congestive heart failure and for defibrillating and/or pacing/sensing
US20070106336A1 (en) * 2003-11-07 2007-05-10 Alan Schaer Cardiac harness assembly for treating congestive heart failure and for pacing/sensing
US20050171589A1 (en) * 2003-11-07 2005-08-04 Lilip Lau Cardiac harness and method of delivery by minimally invasive access
US20050137673A1 (en) * 2003-11-07 2005-06-23 Lilip Lau Cardiac harness having electrodes and epicardial leads
US20050137626A1 (en) * 2003-12-19 2005-06-23 Pastore Joseph M. Drug delivery system and method employing external drug delivery device in conjunction with computer network
US7282024B2 (en) * 2004-01-12 2007-10-16 Paracor Medical, Inc. Cardiac harness having interconnected strands
US7286884B2 (en) 2004-01-16 2007-10-23 Medtronic, Inc. Implantable lead including sensor
US20050159801A1 (en) * 2004-01-16 2005-07-21 Medtronic, Inc. Novel implantable lead including sensor
US20050187545A1 (en) * 2004-02-20 2005-08-25 Hooven Michael D. Magnetic catheter ablation device and method
US7840263B2 (en) * 2004-02-27 2010-11-23 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression
US7620458B2 (en) * 2004-03-09 2009-11-17 Mayo Foundation For Medical Education And Research Sheath and electrical lead
US11779768B2 (en) 2004-03-10 2023-10-10 Impulse Dynamics Nv Protein activity modification
WO2006119467A2 (en) 2005-05-04 2006-11-09 Impulse Dynamics Nv Protein activity modification
US8352031B2 (en) * 2004-03-10 2013-01-08 Impulse Dynamics Nv Protein activity modification
US20070150008A1 (en) * 2004-03-25 2007-06-28 Koninklijke Philips Electronics, N.V. Defibrillation electrode having drug delivery capablity
US7530980B2 (en) * 2004-04-14 2009-05-12 Atricure, Inc Bipolar transmural ablation method and apparatus
WO2005120376A2 (en) * 2004-06-02 2005-12-22 Medtronic, Inc. Ablation device with jaws
US7764995B2 (en) 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
DE202004009224U1 (de) * 2004-06-14 2004-08-12 Isra Vision Systems Ag Sensor zur Vermessung der Oberfläche eines Objekts
US20060009675A1 (en) * 2004-07-08 2006-01-12 Steven Meyer Self-anchoring cardiac harness for treating the heart and for defibrillating and/or pacing/sensing
US7729761B2 (en) * 2004-07-14 2010-06-01 Cardiac Pacemakers, Inc. Method and apparatus for controlled gene or protein delivery
US7567841B2 (en) * 2004-08-20 2009-07-28 Cardiac Pacemakers, Inc. Method and apparatus for delivering combined electrical and drug therapies
US8401637B2 (en) * 2004-11-24 2013-03-19 Galvani, Ltd. Medium voltage therapy applications in treating cardiac arrest
US20060129026A1 (en) * 2004-12-15 2006-06-15 Joshua Wallin Apparatus and method for mounting a cardiac harness on the heart
US7981065B2 (en) 2004-12-20 2011-07-19 Cardiac Pacemakers, Inc. Lead electrode incorporating extracellular matrix
US8060219B2 (en) * 2004-12-20 2011-11-15 Cardiac Pacemakers, Inc. Epicardial patch including isolated extracellular matrix with pacing electrodes
US9821158B2 (en) 2005-02-17 2017-11-21 Metacure Limited Non-immediate effects of therapy
US8244371B2 (en) * 2005-03-18 2012-08-14 Metacure Limited Pancreas lead
US20070032696A1 (en) * 2005-07-22 2007-02-08 Sieu Duong Cardiac harness delivery device
US7587247B2 (en) * 2005-08-01 2009-09-08 Paracor Medical, Inc. Cardiac harness having an optimal impedance range
US20070043412A1 (en) * 2005-08-18 2007-02-22 Herve Janssens Cardiac electrode assembly
US7616990B2 (en) 2005-10-24 2009-11-10 Cardiac Pacemakers, Inc. Implantable and rechargeable neural stimulator
US20070208217A1 (en) * 2006-03-03 2007-09-06 Acorn Cardiovascular, Inc. Self-adjusting attachment structure for a cardiac support device
US7727142B2 (en) * 2006-03-03 2010-06-01 Acorn Cardiovascular, Inc. Delivery tool for cardiac support device
US20070270882A1 (en) * 2006-05-19 2007-11-22 Acorn Cardiovascular, Inc. Pericardium management method for intra-pericardial surgical procedures
US20070287883A1 (en) * 2006-06-07 2007-12-13 Lilip Lau Apparatus and method for pulling a cardiac harness onto a heart
US20080004488A1 (en) * 2006-06-29 2008-01-03 Acorn Cardiovascular, Inc. Low friction delivery tool for a cardiac support device
US7651462B2 (en) * 2006-07-17 2010-01-26 Acorn Cardiovascular, Inc. Cardiac support device delivery tool with release mechanism
CA2661879A1 (en) * 2006-09-05 2008-03-13 Tti Ellebeau, Inc. Transdermal drug delivery systems, devices, and methods using inductive power supplies
US7641608B1 (en) 2006-09-26 2010-01-05 Acorn Cardiovascular, Inc. Sectional cardiac support device and method of delivery
US8641660B2 (en) * 2006-10-04 2014-02-04 P Tech, Llc Methods and devices for controlling biologic microenvironments
US20090036875A1 (en) * 2007-07-30 2009-02-05 Robert Glenmore Walsh Cardiac tissue therapy
US20090036965A1 (en) * 2007-07-30 2009-02-05 Robert Glenmore Walsh Conjunctive stent therapy
US8192351B2 (en) 2007-08-13 2012-06-05 Paracor Medical, Inc. Medical device delivery system having integrated introducer
US20090048480A1 (en) * 2007-08-13 2009-02-19 Paracor Medical, Inc. Cardiac harness delivery device
US8092363B2 (en) * 2007-09-05 2012-01-10 Mardil, Inc. Heart band with fillable chambers to modify heart valve function
US20090281372A1 (en) * 2008-05-06 2009-11-12 Paracor Medical, Inc. Cardiac harness assembly for treating congestive heart failure and for defibrillation and/or pacing/sensing
EP2337607B1 (de) * 2008-10-15 2018-06-13 Med-El Elektromedizinische Geräte GmbH Vorrichtung zur abgabe von arzneimitteln an das innenohr
EP2376180B1 (de) * 2008-11-10 2017-06-28 MED-EL Elektromedizinische Geräte GmbH Mit hydrogel gefüllte aufnahmebehälter zur abgabe von arzneimitteln
EP2401027B1 (de) * 2009-02-26 2017-11-01 The University of North Carolina At Chapel Hill Interventionelles arzneimittelabgabesystem
US8483822B1 (en) 2009-07-02 2013-07-09 Galvani, Ltd. Adaptive medium voltage therapy for cardiac arrhythmias
US8396563B2 (en) 2010-01-29 2013-03-12 Medtronic, Inc. Clock synchronization in an implantable medical device system
US8934975B2 (en) 2010-02-01 2015-01-13 Metacure Limited Gastrointestinal electrical therapy
US8663202B2 (en) * 2011-05-20 2014-03-04 Advastim, Inc. Wireless remote neurostimulator
US9107571B2 (en) 2012-04-24 2015-08-18 Cardimetrix, Llc ECG acquisition and treatment-response system for treating abnormal cardiac function
US8761717B1 (en) 2012-08-07 2014-06-24 Brian K. Buchheit Safety feature to disable an electronic device when a wireless implantable medical device (IMD) is proximate
US9370425B2 (en) 2012-10-12 2016-06-21 Mardil, Inc. Cardiac treatment system and method
US8750990B1 (en) 2012-12-12 2014-06-10 Galvani, Ltd. Coordinated medium voltage therapy for improving effectiveness of defibrillation therapy
USD717954S1 (en) 2013-10-14 2014-11-18 Mardil, Inc. Heart treatment device
KR102907442B1 (ko) * 2018-11-26 2026-01-02 포칼 메디컬, 아이엔씨. 중재적 약물 전달을 위한 의료 기기 및 시스템과 함께 사용하기 위한 이식 가능한 저장소

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5031747A (de) * 1973-07-20 1975-03-28
US4146029A (en) * 1974-04-23 1979-03-27 Ellinwood Jr Everett H Self-powered implanted programmable medication system and method
SU619190A1 (ru) * 1976-12-25 1978-08-15 Научно-Исследовательский Институт Курортологии И Физиотерапии Им.А.А.Акопяна Способ лечени больных,перенесших инфаркт миокарда
CA1174284A (en) * 1980-09-02 1984-09-11 Medtronic, Inc. Body implantable lead
SU1017348A1 (ru) * 1981-05-14 1983-05-15 Украинский Институт Усовершенствования Врачей Способ лечени хронической ишемической болезни сердца
US4477971A (en) * 1981-11-06 1984-10-23 Motion Control, Inc. Iontophoretic electrode structure
US4639244A (en) * 1983-05-03 1987-01-27 Nabil I. Rizk Implantable electrophoretic pump for ionic drugs and associated methods
US4577642A (en) * 1985-02-27 1986-03-25 Medtronic, Inc. Drug dispensing body implantable lead employing molecular sieves and methods of fabrication
GB2175207B (en) * 1985-05-20 1989-07-05 Nabil Ibraham Rizk Improvements in or relating to implantable electrophoretic pumps
DE3521874A1 (de) * 1985-06-19 1987-01-02 Osypka Peter Herzschrittmacher
US4784161A (en) * 1986-11-24 1988-11-15 Telectronics, N.V. Porous pacemaker electrode tip using a porous substrate
US4827932A (en) * 1987-02-27 1989-05-09 Intermedics Inc. Implantable defibrillation electrodes
US4817608A (en) * 1987-05-29 1989-04-04 Mieczyslaw Mirowski Cardioverting transvenous catheter/patch electrode system and method for its use
DE3735137A1 (de) * 1987-10-16 1989-05-03 Siemens Ag Anordnung zum abgeben von medikamenten bei einem implantierbaren medizinischen geraet
US4819662A (en) * 1987-10-26 1989-04-11 Cardiac Pacemakers, Inc. Cardiac electrode with drug delivery capabilities
US4898585A (en) * 1988-05-18 1990-02-06 Baxter Healthcare Corporation Implantable patient-activated fluid delivery device with bolus injection port
CA1327838C (fr) * 1988-06-13 1994-03-15 Fred Zacouto Dispositif implantable de protection contre les affections liees a la coagulation sanguine

Also Published As

Publication number Publication date
DE69112533T2 (de) 1996-02-08
JPH05115562A (ja) 1993-05-14
CA2044791C (en) 1998-07-14
EP0468636A1 (de) 1992-01-29
US5087243A (en) 1992-02-11
JP2686383B2 (ja) 1997-12-08
EP0468636B1 (de) 1995-08-30
CA2044791A1 (en) 1991-12-19
DE69112533D1 (de) 1995-10-05

Similar Documents

Publication Publication Date Title
ATE127028T1 (de) Einpflanzbares iontophoretisches abgabesystem.
US5540669A (en) Iontophoretic drug delivery system and method for using same
KR100482229B1 (ko) 전기운반작용제전달방법및장치
KR0154112B1 (ko) 펄스 상태의 이온침투약 전달방법 및 장치
JP3300953B2 (ja) 体動制御型電子伝達薬剤供給装置
AU7354591A (en) Implantable intravenous cardiac stimulation system with pulse generator housing serving as optional additional electrode
US5795321A (en) Iontophoretic drug delivery system, including removable controller
KR100376723B1 (ko) 전기수송전달장치
DE3174924D1 (en) Perioperative application of electronic pain control in combination with anesthetic agents
IE83865B1 (en) Iontophoretic delivery device
US5954684A (en) Iontophoretic drug delivery system and method for using same
JPH05506165A (ja) イオン導入用送出装置
GB9211085D0 (en) Electrical stimulation
US6718201B1 (en) Electrotransport agent delivery method and apparatus
MX9708823A (es) Dispositivo de electrotransporte que tiene un controlador que se puede volver a usar.
AU1612588A (en) Pulsating transdermal drug delivery system
CA2201378A1 (en) Iontophoretic drug delivery system, including disposable patch and reusable, removable controller
WO1996010441A9 (en) Iontophoretic drug delivery system, including disposable patch and reusable, removable controller
GB2204497A (en) Electrode assembly for transdermal drug delivery
US7572252B1 (en) Electrotransport agent delivery method and apparatus
DE69230063D1 (de) Elektrisches Gerät zur transdermalen Verabreichung von Medikamenten mit einem entgegenwirkenden Produkt

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee