ATE128128T1 - Antiatherosclerotische und antithrombotische 2- amino-6-phenyl-4h-pyran-4-one. - Google Patents

Antiatherosclerotische und antithrombotische 2- amino-6-phenyl-4h-pyran-4-one.

Info

Publication number
ATE128128T1
ATE128128T1 AT91910593T AT91910593T ATE128128T1 AT E128128 T1 ATE128128 T1 AT E128128T1 AT 91910593 T AT91910593 T AT 91910593T AT 91910593 T AT91910593 T AT 91910593T AT E128128 T1 ATE128128 T1 AT E128128T1
Authority
AT
Austria
Prior art keywords
antiatherosclerotic
antithrbotic
pyran
phenyl
amino
Prior art date
Application number
AT91910593T
Other languages
English (en)
Inventor
Joel Morris
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of ATE128128T1 publication Critical patent/ATE128128T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
AT91910593T 1990-06-29 1991-06-03 Antiatherosclerotische und antithrombotische 2- amino-6-phenyl-4h-pyran-4-one. ATE128128T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54593590A 1990-06-29 1990-06-29

Publications (1)

Publication Number Publication Date
ATE128128T1 true ATE128128T1 (de) 1995-10-15

Family

ID=24178137

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91910593T ATE128128T1 (de) 1990-06-29 1991-06-03 Antiatherosclerotische und antithrombotische 2- amino-6-phenyl-4h-pyran-4-one.

Country Status (11)

Country Link
EP (1) EP0489877B1 (de)
JP (1) JPH05501886A (de)
KR (1) KR920702353A (de)
AT (1) ATE128128T1 (de)
AU (1) AU630822B2 (de)
CA (1) CA2064796A1 (de)
DE (1) DE69113221T2 (de)
DK (1) DK0489877T3 (de)
ES (1) ES2079068T3 (de)
GR (1) GR3018304T3 (de)
WO (1) WO1992000290A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2687674B1 (fr) * 1992-02-07 1995-05-19 Roussel Uclaf Nouveaux derives de la pyridone, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
US5834024A (en) * 1995-01-05 1998-11-10 Fh Faulding & Co. Limited Controlled absorption diltiazem pharmaceutical formulation
TW587079B (en) * 1998-09-25 2004-05-11 Almirall Prodesfarma Ag 2-phenylpyran-4-one derivatives
PT1268463E (pt) * 2000-04-05 2005-05-31 Pharmacia Corp 4-pironas substituidas com arilo e heteroarilo policiclicos uteis para a inibicao selectiva da cascata de coagulacao
GB2405093B (en) * 2001-08-14 2005-07-06 Cancer Rec Tech Ltd DNA-PK inhibitors
GB0119863D0 (en) 2001-08-14 2001-10-10 Cancer Res Campaign Tech DNA-PK inhibitors
GB0119865D0 (en) 2001-08-14 2001-10-10 Cancer Res Campaign Tech DNA-PK inhibitors
US7049313B2 (en) 2002-02-25 2006-05-23 Kudos Pharmaceuticals Ltd. ATM inhibitors
BR0307944A (pt) * 2002-02-25 2005-02-01 Kudos Pharm Ltd Piranonas úteis como inibidores de atm
GB0204350D0 (en) * 2002-02-25 2002-04-10 Kudos Pharm Ltd ATM inhibitors
DE602004026071D1 (de) 2003-08-13 2010-04-29 Kudos Pharm Ltd Aminopyrone und ihre verwendung als atm inhibitoren
RU2408596C2 (ru) 2004-09-20 2011-01-10 Кудос Фармасьютикалс Лимитед Ингибиторы днк-пк
WO2006085067A1 (en) 2005-02-09 2006-08-17 Kudos Pharmaceuticals Limited Atm inhibitors
AR053358A1 (es) 2005-04-15 2007-05-02 Cancer Rec Tech Ltd Inhibidores de adn - pk
ES2534573T3 (es) 2007-04-06 2015-04-24 Neurocrine Biosciences, Inc. Antagonistas del receptor de la hormona liberadora de gonadotropina y métodos relacionados con los mismos
CL2008000986A1 (es) 2007-04-06 2008-10-17 Neurocrine Biosciences Inc COMPUESTO DERIVADO DE HETEROCICLOS DE NITROGENO, AGONISTAS DEL RECEPTOR GnRH; COMPOSICION FARMACEUTICA QUE COMPRENDE A DICHO COMPUESTO; Y USO PARA TRATAR UNA AFECCION RELACIONADA CON LAS HORMONAS SEXUALES, ENDOMETRIOSIS, DISMENORREA, ENFERMEDAD DE OV
CN102731456B (zh) * 2011-04-01 2014-07-09 华中科技大学 一种抗肿瘤化合物及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2452487A1 (fr) * 1979-03-28 1980-10-24 Rhone Poulenc Agrochimie Nouveaux derives de la phenyl-2-pyrone-4 et leur utilisation comme fongicides
RU2118321C1 (ru) * 1988-12-21 1998-08-27 Дзе Апджон Компани Замещенные бензопираноны и их фармацевтически приемлемые соли и гидраты

Also Published As

Publication number Publication date
GR3018304T3 (en) 1996-03-31
DE69113221D1 (en) 1995-10-26
EP0489877A1 (de) 1992-06-17
WO1992000290A1 (en) 1992-01-09
AU7955491A (en) 1992-01-23
DK0489877T3 (da) 1996-02-05
DE69113221T2 (de) 1996-03-28
KR920702353A (ko) 1992-09-03
CA2064796A1 (en) 1991-12-30
AU630822B2 (en) 1992-11-05
ES2079068T3 (es) 1996-01-01
EP0489877B1 (de) 1995-09-20
JPH05501886A (ja) 1993-04-08

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee