ATE129155T1 - Verwendung von phosphatidylglycerol(dic 18:10) zur behandlung obstruktiver atemwegserkrankungen. - Google Patents
Verwendung von phosphatidylglycerol(dic 18:10) zur behandlung obstruktiver atemwegserkrankungen.Info
- Publication number
- ATE129155T1 ATE129155T1 AT91400304T AT91400304T ATE129155T1 AT E129155 T1 ATE129155 T1 AT E129155T1 AT 91400304 T AT91400304 T AT 91400304T AT 91400304 T AT91400304 T AT 91400304T AT E129155 T1 ATE129155 T1 AT E129155T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- dic
- respiratory diseases
- phosphatidyl glycerol
- obstructive respiratory
- Prior art date
Links
- ATBOMIWRCZXYSZ-XZBBILGWSA-N [1-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxy-3-hexadecanoyloxypropan-2-yl] (9e,12e)-octadeca-9,12-dienoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(COP(O)(=O)OCC(O)CO)OC(=O)CCCCCCC\C=C\C\C=C\CCCCC ATBOMIWRCZXYSZ-XZBBILGWSA-N 0.000 title 1
- AWUCVROLDVIAJX-UHFFFAOYSA-N alpha-glycerophosphate Natural products OCC(O)COP(O)(O)=O AWUCVROLDVIAJX-UHFFFAOYSA-N 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000000414 obstructive effect Effects 0.000 title 1
- 230000000241 respiratory effect Effects 0.000 title 1
- 150000003904 phospholipids Chemical class 0.000 abstract 2
- 235000011187 glycerol Nutrition 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000008103 phosphatidic acids Chemical class 0.000 abstract 1
- -1 phosphatidyl glycerols Chemical class 0.000 abstract 1
- 150000008105 phosphatidylcholines Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR909001999A FR2658418B1 (fr) | 1990-02-20 | 1990-02-20 | Compositions pharmaceutiques a base de phospholipides. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE129155T1 true ATE129155T1 (de) | 1995-11-15 |
Family
ID=9393891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91400304T ATE129155T1 (de) | 1990-02-20 | 1991-02-08 | Verwendung von phosphatidylglycerol(dic 18:10) zur behandlung obstruktiver atemwegserkrankungen. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5262405A (de) |
| EP (1) | EP0450991B1 (de) |
| JP (1) | JPH04211014A (de) |
| KR (1) | KR910021246A (de) |
| AT (1) | ATE129155T1 (de) |
| CA (1) | CA2036629A1 (de) |
| DE (1) | DE69113848T2 (de) |
| DK (1) | DK0450991T3 (de) |
| FR (1) | FR2658418B1 (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5698537A (en) * | 1996-06-18 | 1997-12-16 | Clarion Pharmaceuticals Inc. | Method of lowering the viscosity of mucus |
| CA2294900A1 (en) * | 1997-07-02 | 1999-01-14 | Sdg, Inc. | Targeted liposomal constructs for diagnostic and therapeutic uses |
| IL121322A (en) * | 1997-07-16 | 2002-07-25 | Modus Biolog Membranes Ltd | Modular pharmacological preparation of the immune system based on fats and its preparation |
| US6309623B1 (en) | 1997-09-29 | 2001-10-30 | Inhale Therapeutic Systems, Inc. | Stabilized preparations for use in metered dose inhalers |
| US6565885B1 (en) | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
| US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
| DE19909115A1 (de) * | 1999-03-03 | 2000-09-07 | Florian Lang | Verwendung von Ceramiden zur Behandlung cystischer Fibrose |
| DE10012151A1 (de) * | 2000-03-13 | 2001-09-27 | Gsf Forschungszentrum Umwelt | Mittel zur Behandlung von Erkrankungen des Tracheo-Brochialtraktes, insbesondere der COPD |
| US8404217B2 (en) | 2000-05-10 | 2013-03-26 | Novartis Ag | Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use |
| WO2001085136A2 (en) | 2000-05-10 | 2001-11-15 | Alliance Pharmaceutical Corporation | Phospholipid-based powders for drug delivery |
| US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
| JP2005514393A (ja) | 2001-12-19 | 2005-05-19 | ネクター セラピューティクス | アミノグリコシドの肺への供給 |
| CA2368656A1 (en) * | 2002-01-21 | 2003-07-21 | Vasogen Ireland Limited | Receptor-ligand pairing for anti-inflammatory response |
| US20050058698A1 (en) * | 2002-01-21 | 2005-03-17 | Nolan Yvonne Mairead | Pharmaceutically acceptable phosphate-glycerol carrying bodies and uses relating to Parkinson's Disease |
| EP1658086A2 (de) * | 2003-07-21 | 2006-05-24 | Vasogen Ireland Limited | Liposome mit phosphatglycerol-gruppen zur behandlung eines akuten entzündungszustands |
| GB0322448D0 (en) * | 2003-09-25 | 2003-10-29 | Lamellar Therapeutics Ltd | Using lamellar bodies to modify linear biological macro molecules |
| US20060078506A1 (en) * | 2004-05-20 | 2006-04-13 | Ralph Niven | Methods, systems and devices for noninvasive pulmonary delivery |
| US8028697B2 (en) | 2005-04-28 | 2011-10-04 | Trudell Medical International | Ventilator circuit and method for the use thereof |
| EP2049554A4 (de) * | 2006-07-20 | 2011-06-29 | Univ Rochester Medical Ct | Synthetisches lungensurfaktant und seine verwendung |
| HRP20160258T1 (hr) | 2008-03-17 | 2016-04-22 | Discovery Laboratories, Inc. | Adapter za cijevni sustav ventilacije i proksimalni sustav za dovođenje aerosola |
| ES2402241T3 (es) | 2008-10-22 | 2013-04-30 | Trudell Medical International | Sistema de suministro de aerosol modular |
| US9585930B2 (en) * | 2011-03-20 | 2017-03-07 | Trustees Of Boston University | Therapeutic agent for emphysema and COPD |
| EP3377043A4 (de) * | 2015-11-20 | 2019-06-26 | The Regents of The University of California | Verformbare nanoskalige trägerstoffe (dnvs) für verabreichung über die blut-hirn-schranke, schleimhäute und haut |
| US12514929B2 (en) | 2017-04-03 | 2026-01-06 | The Regents Of The University Of California | Deformable nano-scale vehicles (DNVS) for trans-blood brain barrier, trans-mucosal, and transdermal drug delivery |
| US12329759B2 (en) | 2019-10-17 | 2025-06-17 | Trustees Of Boston University | Methods and compositions relating to lung function |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2343481A1 (fr) * | 1976-03-11 | 1977-10-07 | Gerlich Norbert | Composition destinee a empecher les lesions des membranes biologiques et a regenerer ces membranes une fois qu'elles ont ete endommagees |
| GB2045612B (en) * | 1979-03-27 | 1983-04-20 | Nippon Shoji Kaisha Ltd | Pharmaceutical compositions containing phosphatidic acids for the treatment of disorders of consciousness perception and movement |
| US4725588A (en) * | 1979-11-07 | 1988-02-16 | The United States Of America As Represented By The United States Department Of Energy | Alkyl phospholipid antihypertensive agents in method of lowering blood pressure |
| US4666893A (en) * | 1983-02-15 | 1987-05-19 | St. Thomas Institute | Methods of inducing resistance to bacterial and viral infections |
| JPS59164724A (ja) * | 1983-03-10 | 1984-09-17 | Tokyo Tanabe Co Ltd | サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤 |
| IL71051A (en) * | 1984-02-23 | 1988-02-29 | Yeda Res & Dev | Compositions containing active lipids for the treatment of cystic fibrosis |
| FR2586587B1 (fr) * | 1985-08-30 | 1987-10-23 | Adir | Nouveaux surfactants artificiels, leur preparation et les compositions pharmaceutiques qui les contiennent. |
| GB8522964D0 (en) * | 1985-09-17 | 1985-10-23 | Biocompatibles Ltd | Aerosol |
| US5032585A (en) * | 1987-02-17 | 1991-07-16 | Board Of Regents, The University Of Texas System | Methods and compositions employing unique mixtures of polar and neutral lipids for surfactant replacement therapy |
| IT1212137B (it) * | 1987-04-08 | 1989-11-08 | Rosanna Lodi | Composizioni farmaceutiche per il trattamento di sindromi psico-organiche cerebrali. |
| US4997761A (en) * | 1987-10-06 | 1991-03-05 | Houston Biotechnology Incorporated | Phosphatidyl treatment of viral disease |
| WO1989005152A1 (en) * | 1987-12-09 | 1989-06-15 | The Regents Of The University Of California | Liposome-encapsulated anti-viral composition and method |
| CA2037478A1 (en) * | 1990-03-05 | 1991-09-06 | Richard Gregory | Diagnostic and treatment methods involving the cystic fibrosis transmembrane regulator |
-
1990
- 1990-02-20 FR FR909001999A patent/FR2658418B1/fr not_active Expired - Fee Related
-
1991
- 1991-02-08 EP EP91400304A patent/EP0450991B1/de not_active Expired - Lifetime
- 1991-02-08 AT AT91400304T patent/ATE129155T1/de not_active IP Right Cessation
- 1991-02-08 DK DK91400304.1T patent/DK0450991T3/da active
- 1991-02-08 DE DE69113848T patent/DE69113848T2/de not_active Expired - Fee Related
- 1991-02-19 CA CA002036629A patent/CA2036629A1/fr not_active Abandoned
- 1991-02-19 KR KR1019910002646A patent/KR910021246A/ko not_active Withdrawn
- 1991-02-19 JP JP3047681A patent/JPH04211014A/ja active Pending
- 1991-02-20 US US07/658,330 patent/US5262405A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| FR2658418B1 (fr) | 1994-09-02 |
| JPH04211014A (ja) | 1992-08-03 |
| DE69113848T2 (de) | 1996-04-25 |
| EP0450991B1 (de) | 1995-10-18 |
| DK0450991T3 (da) | 1996-03-04 |
| KR910021246A (ko) | 1991-12-20 |
| DE69113848D1 (de) | 1995-11-23 |
| EP0450991A2 (de) | 1991-10-09 |
| CA2036629A1 (fr) | 1991-08-21 |
| EP0450991A3 (en) | 1992-12-16 |
| FR2658418A1 (fr) | 1991-08-23 |
| US5262405A (en) | 1993-11-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |