ATE131481T1 - Metalloporphyrinderivate, ihre herstellung, ihre therapeutische anwendung und ihre anwendung zur herstellung von hybridischen molekülen - Google Patents

Metalloporphyrinderivate, ihre herstellung, ihre therapeutische anwendung und ihre anwendung zur herstellung von hybridischen molekülen

Info

Publication number
ATE131481T1
ATE131481T1 AT89401533T AT89401533T ATE131481T1 AT E131481 T1 ATE131481 T1 AT E131481T1 AT 89401533 T AT89401533 T AT 89401533T AT 89401533 T AT89401533 T AT 89401533T AT E131481 T1 ATE131481 T1 AT E131481T1
Authority
AT
Austria
Prior art keywords
production
application
pct
derivatives
linear
Prior art date
Application number
AT89401533T
Other languages
English (en)
Inventor
Bernard Meunier
Guita Etemad-Moghadam
Li Ding
Suzy Cros
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Application granted granted Critical
Publication of ATE131481T1 publication Critical patent/ATE131481T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/02—Iron compounds
    • C07F15/025—Iron compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/04—Nickel compounds
    • C07F15/045—Nickel compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F19/00—Metal compounds according to more than one of main groups C07F1/00 - C07F17/00
    • C07F19/005—Metal compounds according to more than one of main groups C07F1/00 - C07F17/00 without metal-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/06—Zinc compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT89401533T 1988-06-02 1989-06-02 Metalloporphyrinderivate, ihre herstellung, ihre therapeutische anwendung und ihre anwendung zur herstellung von hybridischen molekülen ATE131481T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8807372A FR2632187B1 (fr) 1988-06-02 1988-06-02 Derives de metalloporphyrines, leur preparation, leur application en therapeutique et leur utilisation pour la preparation de molecules hybrides

Publications (1)

Publication Number Publication Date
ATE131481T1 true ATE131481T1 (de) 1995-12-15

Family

ID=9366884

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89401533T ATE131481T1 (de) 1988-06-02 1989-06-02 Metalloporphyrinderivate, ihre herstellung, ihre therapeutische anwendung und ihre anwendung zur herstellung von hybridischen molekülen

Country Status (10)

Country Link
US (1) US5236914A (de)
EP (1) EP0345171B1 (de)
JP (1) JPH03504725A (de)
AT (1) ATE131481T1 (de)
AU (1) AU3832789A (de)
CA (1) CA1333602C (de)
DE (1) DE68925067D1 (de)
FR (1) FR2632187B1 (de)
WO (1) WO1989012049A1 (de)
ZA (1) ZA894185B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2656866B1 (fr) * 1990-01-10 1992-05-15 Cis Bio Int Derives de porphyrine et metalloporphyrines eventuellement couples a une molecule biologiquement active, et composition pharmaceutique les contenant.
FR2697254A1 (fr) * 1992-10-22 1994-04-29 Genset Sa Conjugués constitués par un oligonucléotide lié à des dérivés de métalloporphyrine cationique, leur préparation et leur utilisation.
US5994339A (en) * 1993-10-15 1999-11-30 University Of Alabama At Birmingham Research Foundation Oxidant scavengers
US6127356A (en) 1993-10-15 2000-10-03 Duke University Oxidant scavengers
WO1996009053A1 (en) * 1994-09-20 1996-03-28 Duke University Oxidoreductase activity of manganic porphyrins
DE69635304T2 (de) * 1995-06-07 2006-07-20 Duke University Faenger fuer oxidantien
US5877165A (en) * 1995-11-02 1999-03-02 Brookhaven Science Associates Boronated porhyrins and methods for their use
US6620805B1 (en) 1996-03-14 2003-09-16 Yale University Delivery of nucleic acids by porphyrins
AU6650198A (en) * 1997-02-05 1998-08-25 Board Of Regents, The University Of Texas System Porphyrin compounds as telomerase inhibitors
DE19743903A1 (de) * 1997-07-16 1999-04-15 Deutsch Zentr Luft & Raumfahrt Verwendung von metallierten und/oder unmetallierten polymergebundenen Porphyrinen
DE69813898T2 (de) 1997-11-03 2004-03-11 Duke University Substituierte porphyrinen
DK1071474T3 (da) 1998-04-24 2006-04-10 Univ Duke Substituerede porphyriner
DE19840608A1 (de) * 1998-09-05 2000-03-09 Dlr Ev Metallierte oder unmetallierte Phthalocyanine
IL126953A0 (en) 1998-11-08 1999-09-22 Yeda Res & Dev Pharmaceutical compositions comprising porphyrins and some novel porphyrin derivatives
ATE312103T1 (de) 1999-01-25 2005-12-15 Nat Jewish Med & Res Center Substituierte porphyrine und deren therapeutische verwendungen
US6403788B1 (en) * 2000-07-11 2002-06-11 Eukarion, Inc. Non-genotoxic metalloporphyrins as synthetic catalytic scavengers of reactive oxygen species
DK1392328T3 (da) 2001-01-19 2009-11-09 Nat Jewish Health Medikament til beskyttelse i radioterapi
EP1439842A4 (de) * 2001-06-01 2009-09-02 Nat Jewish Med & Res Center Oxidantienfänger zur behandlung von diabetes oder zur verwendung bei der transplantation oder induktion von immuntoleranz
WO2003103680A1 (en) * 2002-06-07 2003-12-18 Duke University Substituted porphyrins
ITFI20020200A1 (it) * 2002-10-21 2004-04-22 Molteni & C Dei Flii Alitti S P A Societa L Porfirine meso-sostituite.
GB2397067B (en) * 2002-12-23 2005-05-11 Destiny Pharma Ltd Porphin & azaporphin derivatives with at least one cationic-nitrogen-containing meso-substituent for use in photodynamic therapy & in vitro sterilisation
GB2415372A (en) 2004-06-23 2005-12-28 Destiny Pharma Ltd Non photodynamical or sonodynamical antimicrobial use of porphyrins and azaporphyrins containing at least one cationic-nitrogen-containing substituent
GB0602125D0 (en) * 2006-02-03 2006-03-15 Univ Belfast Sensitizer-incorporated biomaterials
DK2300003T3 (da) 2008-05-23 2014-05-26 Nat Jewish Health Forbindelser til anvendelse i behandling af skade forbundet med eksponering for en alkylerende art
FR2935974B1 (fr) * 2008-09-15 2010-10-08 Centre Nat Rech Scient Derives de metalloporphyrines, nanoparticules les comprenant
FR2988721B1 (fr) 2012-03-27 2014-04-04 Centre Nat Rech Scient Nanoparticules de silicium poreux fonctionnalisees et leurs utilisations en therapie photodynamique
CN116589024B (zh) * 2023-06-05 2026-02-13 河海大学 一种促进水体中阿奇霉素光降解的方法及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2740794A (en) * 1954-07-26 1956-04-03 Exxon Research Engineering Co Synthesis of novel vanadium porphyrin
US4386087A (en) * 1981-07-01 1983-05-31 Research Foundation Of The City University Of New York N-Substituted metalloporphyrins as anti-tumor agents against PS-P-388(P388) leukemia in animals
JPS60126291A (ja) * 1983-03-14 1985-07-05 Koichi Shiyudo ポルフイリン誘導体
DE3464252D1 (en) * 1983-06-03 1987-07-23 Hoffmann La Roche Labelled molecules for fluorescence immunoassays and processes and intermediates for their preparation
GB8429845D0 (en) * 1984-11-26 1985-01-03 Efamol Ltd Porphyrins & cancer treatment

Also Published As

Publication number Publication date
JPH03504725A (ja) 1991-10-17
AU3832789A (en) 1990-01-05
US5236914A (en) 1993-08-17
CA1333602C (fr) 1994-12-20
WO1989012049A1 (fr) 1989-12-14
EP0345171B1 (de) 1995-12-13
FR2632187B1 (fr) 1990-09-14
DE68925067D1 (de) 1996-01-25
FR2632187A1 (fr) 1989-12-08
EP0345171A1 (de) 1989-12-06
ZA894185B (en) 1990-02-28

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