ATE131537T1 - Gegen lepidoptera und coleoptera aktive mikroorganismen, verwandte insektizidzusammensetzungen und verfahren für ihre herstellung und verwendung - Google Patents
Gegen lepidoptera und coleoptera aktive mikroorganismen, verwandte insektizidzusammensetzungen und verfahren für ihre herstellung und verwendungInfo
- Publication number
- ATE131537T1 ATE131537T1 AT88904847T AT88904847T ATE131537T1 AT E131537 T1 ATE131537 T1 AT E131537T1 AT 88904847 T AT88904847 T AT 88904847T AT 88904847 T AT88904847 T AT 88904847T AT E131537 T1 ATE131537 T1 AT E131537T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- coleoptera
- preparation
- active against
- relates
- Prior art date
Links
- 239000002917 insecticide Substances 0.000 title abstract 3
- 241000254173 Coleoptera Species 0.000 title abstract 2
- 244000005700 microbiome Species 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 241000255777 Lepidoptera Species 0.000 title 1
- 241000193388 Bacillus thuringiensis Species 0.000 abstract 2
- 229940097012 bacillus thuringiensis Drugs 0.000 abstract 2
- 239000003053 toxin Substances 0.000 abstract 2
- 231100000765 toxin Toxicity 0.000 abstract 2
- 241000238631 Hexapoda Species 0.000 abstract 1
- 101150102059 cry3Aa gene Proteins 0.000 abstract 1
- 239000002158 endotoxin Substances 0.000 abstract 1
- 230000000749 insecticidal effect Effects 0.000 abstract 1
- 239000013612 plasmid Substances 0.000 abstract 1
- 231100000654 protein toxin Toxicity 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
- C07K14/325—Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/30—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/20—Bacteria; Substances produced thereby or obtained therefrom
- A01N63/22—Bacillus
- A01N63/23—B. thuringiensis
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/50—Isolated enzymes; Isolated proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Plant Pathology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Environmental Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/047,945 US5024837A (en) | 1987-05-06 | 1987-05-06 | Coleopteran active microorganisms, related insecticide compositions and methods for their production and use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE131537T1 true ATE131537T1 (de) | 1995-12-15 |
Family
ID=21951887
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88904847T ATE131537T1 (de) | 1987-05-06 | 1988-05-04 | Gegen lepidoptera und coleoptera aktive mikroorganismen, verwandte insektizidzusammensetzungen und verfahren für ihre herstellung und verwendung |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5024837A (de) |
| EP (1) | EP0359771B1 (de) |
| JP (1) | JPH02501439A (de) |
| KR (1) | KR890700678A (de) |
| AT (1) | ATE131537T1 (de) |
| DE (1) | DE3854787T2 (de) |
| ES (1) | ES2009605A6 (de) |
| FI (1) | FI895227A7 (de) |
| GR (1) | GR1000468B (de) |
| IL (1) | IL86237A (de) |
| WO (1) | WO1988008880A1 (de) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3346138A1 (de) * | 1983-12-21 | 1985-07-11 | Boehringer Mannheim Gmbh, 6800 Mannheim | Bacillus thuringiensis var. tenebrionis sowie ein insektizid wirkendes, hieraus erhaeltliches praeparat bzw. toxin sowie deren verwendung zur bekaempfung von coleoptera |
| US4996155A (en) * | 1988-03-04 | 1991-02-26 | Mycogen Corporation | Bacillus thuringiensis gene encoding a coleopteran-active toxin |
| ATE120801T1 (de) * | 1988-09-06 | 1995-04-15 | Plant Genetic Systems Nv | Pflanzen, die mit einer lepidopteralen dns- sequenz aus bazillus thuringiensis transformiert werden. |
| FR2639959A1 (fr) * | 1988-12-02 | 1990-06-08 | Pasteur Institut | Bacteries recombinantes toxiques vis-a-vis des larves de dipteres et leur utilisation pour l'elaboration de compositions larvicides |
| EP0382990A1 (de) * | 1989-02-15 | 1990-08-22 | Plant Genetic Systems, N.V. | Bazillus Thuringiensis-Stämme |
| US5683691A (en) * | 1989-02-15 | 1997-11-04 | Plant Genetic Systems, N.V. | Bacillus thuringiensis insecticidal toxins |
| AU638438B2 (en) | 1989-02-24 | 1993-07-01 | Monsanto Technology Llc | Synthetic plant genes and method for preparation |
| US5908970A (en) * | 1989-05-31 | 1999-06-01 | Plant Genetic Systems N.V. | Recombinant plant expressing non-competitively binding Bt insecticidal crystal proteins |
| US6855873B1 (en) | 1989-05-31 | 2005-02-15 | Bayer Bioscience, N.V. | Recombinant plant expressing non-competitively binding Bt insecticidal cryatal proteins |
| EP0400246A1 (de) * | 1989-05-31 | 1990-12-05 | Plant Genetic Systems, N.V. | Verhinderung von Resistenzentwicklung gegen Bt |
| US5187091A (en) * | 1990-03-20 | 1993-02-16 | Ecogen Inc. | Bacillus thuringiensis cryiiic gene encoding toxic to coleopteran insects |
| US5264364A (en) * | 1991-01-31 | 1993-11-23 | Ecogen Inc. | Bacillus thuringiensis cryIIIc(B) toxin gene and protein toxic to coleopteran insects |
| CA2101338A1 (en) * | 1991-01-31 | 1992-08-01 | William P. Donovan | Bacillus thuringiensis cryiiic(b) toxin gene and protein toxic to coleopteran insects |
| US5204100A (en) * | 1991-02-01 | 1993-04-20 | Ciba-Geigy Corporation | Baciullus thuringiensis strains active against coleopteran insects |
| US6071511A (en) * | 1991-10-04 | 2000-06-06 | Mycogen Corporation | Bacillus thuringiensis isolates, toxins, and genes selectively active against certain coleopteran pests |
| US5427786A (en) * | 1991-10-04 | 1995-06-27 | Mycogen Corporation | Bacillus thuringiensis isolates selectively active against certain coleopteran pests |
| US5879676A (en) * | 1992-12-15 | 1999-03-09 | Abbott Laboratories | Bacillus thuringiensis strains active against lepidopteran and coleopteran pests |
| US6156308A (en) * | 1992-12-15 | 2000-12-05 | Valent Biosciences, Inc. | Bacillus thuringiensis strains active against lepidopteran and coleopteran pests |
| US5849870A (en) * | 1993-03-25 | 1998-12-15 | Novartis Finance Corporation | Pesticidal proteins and strains |
| US5877012A (en) * | 1993-03-25 | 1999-03-02 | Novartis Finance Corporation | Class of proteins for the control of plant pests |
| RO117111B1 (ro) * | 1993-03-25 | 2001-10-30 | Ciba Geigy Ag | Proteina pesticida si secventa de nucleotide, care o codifica |
| FR2704860B1 (fr) * | 1993-05-05 | 1995-07-13 | Pasteur Institut | Sequences de nucleotides du locus cryiiia pour le controle de l'expression de sequences d'adn dans un hote cellulaire. |
| WO1994028724A1 (en) * | 1993-06-10 | 1994-12-22 | Ecogen Inc. | Bacillus thuringiensis strains capable of producing large amonts of insecticidal crystal proteins |
| US5441884A (en) * | 1993-07-08 | 1995-08-15 | Ecogen Inc. | Bacillus thuringiensis transposon TN5401 |
| US5843744A (en) * | 1993-07-08 | 1998-12-01 | Ecogen Inc. | Bacillus thuringiensis Tn5401 proteins |
| US5976563A (en) * | 1994-03-14 | 1999-11-02 | Abbott Laboratories | Pesticidal composition and Bacillus thuringiensis strain |
| US6063756A (en) | 1996-09-24 | 2000-05-16 | Monsanto Company | Bacillus thuringiensis cryET33 and cryET34 compositions and uses therefor |
| US5942664A (en) * | 1996-11-27 | 1999-08-24 | Ecogen, Inc. | Bacillus thuringiensis Cry1C compositions toxic to lepidopteran insects and methods for making Cry1C mutants |
| IL132039A0 (en) | 1997-04-03 | 2001-03-19 | Novartis Ag | Plant pest control |
| US6023013A (en) * | 1997-12-18 | 2000-02-08 | Monsanto Company | Insect-resistant transgenic plants |
| US6063597A (en) * | 1997-12-18 | 2000-05-16 | Monsanto Company | Polypeptide compositions toxic to coleopteran insects |
| US6060594A (en) * | 1997-12-18 | 2000-05-09 | Ecogen, Inc. | Nucleic acid segments encoding modified bacillus thuringiensis coleopteran-toxic crystal proteins |
| US6077824A (en) * | 1997-12-18 | 2000-06-20 | Ecogen, Inc. | Methods for improving the activity of δ-endotoxins against insect pests |
| HUP0200562A2 (en) | 1999-03-30 | 2002-06-29 | Agraquest Inc | A strain of baccilus pumilus for controlling plant diseases |
| US6245551B1 (en) | 1999-03-30 | 2001-06-12 | Agraquest, Inc. | Strain of Bacillus pumilus for controlling plant diseases caused by fungi |
| US6501009B1 (en) * | 1999-08-19 | 2002-12-31 | Monsanto Technology Llc | Expression of Cry3B insecticidal protein in plants |
| EP1532247A4 (de) * | 2002-07-29 | 2006-08-30 | Monsanto Technology Llc | Maispflanzen des ereignisses pv-zmir13 (mon863) sowie zusammensetzungen und verfahren zum nachweis davon |
| CA2531400A1 (en) * | 2003-07-07 | 2005-03-03 | Monsanto Technology, Llc | Insecticidal proteins secreted from bacillus thuringiensis and uses therefor |
| EP3478052B1 (de) | 2016-07-01 | 2021-08-25 | Pioneer Hi-Bred International, Inc. | Insektizidproteine aus pflanzen und verfahren zu deren verwendung |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5133967B1 (de) * | 1970-11-14 | 1976-09-22 | ||
| US4237224A (en) * | 1974-11-04 | 1980-12-02 | Board Of Trustees Of The Leland Stanford Jr. University | Process for producing biologically functional molecular chimeras |
| US4467036A (en) * | 1981-11-12 | 1984-08-21 | The Board Of Regents Of The University Of Washington | Bacillus thuringiensis crystal protein in Escherichia coli |
| US4448885A (en) * | 1981-04-27 | 1984-05-15 | Board Of The Regents Of The University Of Washington | Bacillus thuringiensis crystal protein in Escherichia coli |
| CA1193564A (en) * | 1982-07-09 | 1985-09-17 | University Of Western Ontario | Mutated microorganism with toxin inclusion for pest control |
| BR8404834A (pt) * | 1983-09-26 | 1985-08-13 | Agrigenetics Res Ass | Metodo para modificar geneticamente uma celula vegetal |
| DE3346138A1 (de) * | 1983-12-21 | 1985-07-11 | Boehringer Mannheim Gmbh, 6800 Mannheim | Bacillus thuringiensis var. tenebrionis sowie ein insektizid wirkendes, hieraus erhaeltliches praeparat bzw. toxin sowie deren verwendung zur bekaempfung von coleoptera |
| GB8425487D0 (en) * | 1984-10-09 | 1984-11-14 | Agricultural Genetics Co | Strain of bacillus thuringiensis |
| BR8600161A (pt) * | 1985-01-18 | 1986-09-23 | Plant Genetic Systems Nv | Gene quimerico,vetores de plasmidio hibrido,intermediario,processo para controlar insetos em agricultura ou horticultura,composicao inseticida,processo para transformar celulas de plantas para expressar uma toxina de polipeptideo produzida por bacillus thuringiensis,planta,semente de planta,cultura de celulas e plasmidio |
| US4771131A (en) * | 1985-08-16 | 1988-09-13 | Mycogen Corporation | Cloning and expression of Bacillus thuringiensis toxin gene encoding a protein toxic to beetles of the order Coleoptera |
| GB8526774D0 (en) * | 1985-10-30 | 1985-12-04 | Sandoz Ltd | Bacillus thuringiensis hybrids |
| US4910016A (en) * | 1987-08-03 | 1990-03-20 | Mycogen Corporation | Novel Bacillus thuringiensis isolate |
-
1987
- 1987-05-06 US US07/047,945 patent/US5024837A/en not_active Expired - Fee Related
-
1988
- 1988-05-01 IL IL8623788A patent/IL86237A/en unknown
- 1988-05-04 AT AT88904847T patent/ATE131537T1/de not_active IP Right Cessation
- 1988-05-04 JP JP63504395A patent/JPH02501439A/ja active Pending
- 1988-05-04 WO PCT/US1988/001495 patent/WO1988008880A1/en not_active Ceased
- 1988-05-04 FI FI895227A patent/FI895227A7/fi not_active IP Right Cessation
- 1988-05-04 DE DE3854787T patent/DE3854787T2/de not_active Expired - Fee Related
- 1988-05-04 EP EP88904847A patent/EP0359771B1/de not_active Expired - Lifetime
- 1988-05-06 ES ES8801399A patent/ES2009605A6/es not_active Expired
- 1988-05-06 GR GR880100295A patent/GR1000468B/el unknown
- 1988-12-26 KR KR1019880701725A patent/KR890700678A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| FI895227A0 (fi) | 1989-11-03 |
| ES2009605A6 (es) | 1989-10-01 |
| DE3854787T2 (de) | 1996-06-13 |
| EP0359771A1 (de) | 1990-03-28 |
| WO1988008880A1 (en) | 1988-11-17 |
| JPH02501439A (ja) | 1990-05-24 |
| US5024837A (en) | 1991-06-18 |
| EP0359771A4 (de) | 1990-06-27 |
| AU1782388A (en) | 1988-12-06 |
| FI895227A7 (fi) | 1989-11-03 |
| IL86237A0 (en) | 1988-11-15 |
| GR1000468B (el) | 1992-07-30 |
| EP0359771B1 (de) | 1995-12-13 |
| AU617110B2 (en) | 1991-11-21 |
| IL86237A (en) | 1994-11-11 |
| DE3854787D1 (de) | 1996-01-25 |
| GR880100295A (en) | 1989-02-23 |
| KR890700678A (ko) | 1989-04-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |