ATE132144T1 - Chalkonderivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten - Google Patents

Chalkonderivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten

Info

Publication number
ATE132144T1
ATE132144T1 AT91401679T AT91401679T ATE132144T1 AT E132144 T1 ATE132144 T1 AT E132144T1 AT 91401679 T AT91401679 T AT 91401679T AT 91401679 T AT91401679 T AT 91401679T AT E132144 T1 ATE132144 T1 AT E132144T1
Authority
AT
Austria
Prior art keywords
group
hydrogen atom
cirf
lower alkyl
case
Prior art date
Application number
AT91401679T
Other languages
English (en)
Inventor
Daniel Lesieur
Daniel-Henri Caignard
Isabelle Lesieur
Michelle Devissaguet
Beatrice Guardiola
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of ATE132144T1 publication Critical patent/ATE132144T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/60—Naphthoxazoles; Hydrogenated naphthoxazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT91401679T 1990-06-22 1991-06-21 Chalkonderivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten ATE132144T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR909007813A FR2663633B1 (fr) 1990-06-22 1990-06-22 Nouvelles chalcones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
ATE132144T1 true ATE132144T1 (de) 1996-01-15

Family

ID=9397889

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91401679T ATE132144T1 (de) 1990-06-22 1991-06-21 Chalkonderivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten

Country Status (16)

Country Link
US (1) US5179091A (de)
EP (1) EP0463945B1 (de)
JP (1) JPH0730054B2 (de)
AT (1) ATE132144T1 (de)
AU (1) AU631743B2 (de)
CA (1) CA2045256A1 (de)
DE (1) DE69115768T2 (de)
DK (1) DK0463945T3 (de)
ES (1) ES2084129T3 (de)
FR (1) FR2663633B1 (de)
GR (1) GR3019019T3 (de)
IE (1) IE912145A1 (de)
NZ (1) NZ238647A (de)
OA (1) OA09504A (de)
PT (1) PT98068A (de)
ZA (1) ZA914802B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992018488A1 (en) * 1991-04-10 1992-10-29 Japan Tobacco Inc. Novel oxazinone derivative
US6140309A (en) * 1996-03-12 2000-10-31 University Of South Florida Vasoactive effects and free radical generation by β-amyloid peptides
US8039026B1 (en) 1997-07-28 2011-10-18 Johnson & Johnson Consumer Companies, Inc Methods for treating skin pigmentation
AU2904899A (en) * 1998-03-16 1999-10-11 Procter & Gamble Company, The Compositions for regulating skin appearance
BR9908222A (pt) 1998-03-16 2000-10-24 Procter & Gamble Composições para regular a aparência da pele
US8093293B2 (en) * 1998-07-06 2012-01-10 Johnson & Johnson Consumer Companies, Inc. Methods for treating skin conditions
US6750229B2 (en) 1998-07-06 2004-06-15 Johnson & Johnson Consumer Companies, Inc. Methods for treating skin pigmentation
US8106094B2 (en) * 1998-07-06 2012-01-31 Johnson & Johnson Consumer Companies, Inc. Compositions and methods for treating skin conditions
US20020197244A1 (en) * 1998-12-07 2002-12-26 Miri Seiberg Compositions and methods for regulating phagocytosis and ICAM-1 expression
US7985404B1 (en) * 1999-07-27 2011-07-26 Johnson & Johnson Consumer Companies, Inc. Reducing hair growth, hair follicle and hair shaft size and hair pigmentation
US7309688B2 (en) * 2000-10-27 2007-12-18 Johnson & Johnson Consumer Companies Topical anti-cancer compositions and methods of use thereof
GB0004686D0 (en) * 2000-02-28 2000-04-19 Aventis Pharma Ltd Chemical compounds
US20040192669A1 (en) 2000-04-13 2004-09-30 Rosenfeld Mark J. Novel compounds for use in weight loss and appetite suppression in humans
US7794761B2 (en) * 2000-04-13 2010-09-14 Seroctin Research & Technology, Inc. Methods for inducing anti-anxiety and calming effects in animals and humans
US8431550B2 (en) * 2000-10-27 2013-04-30 Johnson & Johnson Consumer Companies, Inc. Topical anti-cancer compositions and methods of use thereof
US6555143B2 (en) 2001-02-28 2003-04-29 Johnson & Johnson Consumer Products, Inc. Legume products
US7192615B2 (en) * 2001-02-28 2007-03-20 J&J Consumer Companies, Inc. Compositions containing legume products
MXPA04005864A (es) * 2001-12-19 2004-10-29 Atherogenics Inc Derivados de charcona y su uso para tratar enfermedades.
US20030224075A1 (en) * 2002-02-21 2003-12-04 Jue-Chen Liu Soy composition for balancing combination skin
US20050004561A1 (en) * 2003-07-01 2005-01-06 Lynn Halas Method for removing hair
WO2005048969A1 (en) * 2003-10-29 2005-06-02 Johnson & Johnson Consumer France S.A.S. Compositions comprising soy products and dioic acids
US7524877B2 (en) 2003-11-20 2009-04-28 Seroctin Research & Technology, Inc. Compounds for use in weight loss and appetite suppression in humans
US20080008818A1 (en) * 2006-06-23 2008-01-10 Miri Seiberg Partially denatured whole soybean extracts and methods of use thereof
US20080089960A1 (en) * 2006-10-16 2008-04-17 Miri Seiberg Use of Legume Products for the Treatment and Prevention of Radiotherapy-Induced Skin Damage
CN103360338B (zh) * 2013-07-30 2015-04-01 中国科学院新疆理化技术研究所 一种查尔酮苯并噻唑酰胺类衍生物的制备方法和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2244506B1 (de) * 1973-06-26 1977-02-25 Inst Nat Sante Rech Med
FR2244507A1 (en) * 1973-06-26 1975-04-18 Inst Nat Sante Rech Med Chalcones and analogues - analgesics having low toxicity
FR2588868B1 (fr) * 1985-10-21 1988-11-10 Negma Laboratoires Acyl-7 benzoxazinones et leurs derives, procede pour les obtenir et compositions pharmaceutiques les contenant
FR2646350B1 (fr) * 1989-04-28 1991-06-28 Adir Nouveaux derives benzothiazolinoniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
DK0463945T3 (da) 1996-04-29
FR2663633B1 (fr) 1994-06-17
NZ238647A (en) 1992-08-26
ES2084129T3 (es) 1996-05-01
FR2663633A1 (fr) 1991-12-27
US5179091A (en) 1993-01-12
AU7917291A (en) 1992-01-02
CA2045256A1 (fr) 1991-12-23
EP0463945B1 (de) 1995-12-27
AU631743B2 (en) 1992-12-03
DE69115768D1 (de) 1996-02-08
GR3019019T3 (en) 1996-05-31
PT98068A (pt) 1992-03-31
EP0463945A1 (de) 1992-01-02
OA09504A (fr) 1992-11-15
DE69115768T2 (de) 1996-08-08
IE912145A1 (en) 1992-01-01
JPH04230273A (ja) 1992-08-19
JPH0730054B2 (ja) 1995-04-05
ZA914802B (en) 1992-04-29

Similar Documents

Publication Publication Date Title
ATE132144T1 (de) Chalkonderivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten
ATE9793T1 (de) 5-oxo- und 5-thioxoproline, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
DE58908652D1 (de) Aminoalkylindole, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate.
ATE129503T1 (de) Amidinophenylalaninderivate, verfahren zu deren herstellung, deren verwendung und diese enthaltende mittel als antikoagulantien.
ATE16805T1 (de) Trifluoromethylphenyltetrahydropyridine mit appetithemmender wirkung, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
NZ218243A (en) B-carboline derivatives and pharmaceutical compositions
DE69004815D1 (de) 1,8-Benzonaphthyridinderivate, ihre Herstellung und diese enthaltende Zusammensetzungen.
ATE193531T1 (de) Phenyl-carboxamide-isoxazole-derivate und salze, verfahren zu ihrer herstellung ihre anwendung als arzneimittel und pharmazeutische zusammensetzungen die sie enthalten
IL63782A (en) 2-(1,4-benzodioxan-2-ylalkyl)imidazoles,their preparation and pharmaceutical compositions containing them
ATE107298T1 (de) 3-aminochroman-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
ATE13880T1 (de) N-2-hydroxypropyl-piperidine und verfahren zu ihrer herstellung.
SE8006953L (sv) Heterocykliska foreningar
AU639154B2 (en) New imidazole compounds, a process for the preparation thereof, and pharmaceutical compositions containing them
ES8200648A2 (es) Procedimiento de preparacion de compuestos opacificantes para radiografia y similares
PT76335B (de) Neue basisch substituierte 4-phenyl-4,5,6,7-tetrahydro-thieno-<2,3-c>pyridine verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
ATE19879T1 (de) Furyloxazolylessigsaeure-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
ATE25523T1 (de) Bicyclische phenolether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel.
ATE22284T1 (de) 2-aminomethyl-6-sulfamoylphenolderivate, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen.
ATE1097T1 (de) 4-aminopyridine, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
ATE70050T1 (de) 1-benzoyl-2-oxo-5-alkoxy-pyrrolidin-derivate, ihre herstellung und verwendung als heilmittel und zubereitungen, die sie enthalten.
SE8207294L (sv) 1,4-tiazankarboxylsyraderivat, deras framstellning och anvendning och kompositioner vari dessa derivat ingar
ATE53839T1 (de) 2,3-dihydro-3-phenyl-benzofuran-2-onacetamidderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
ATE132867T1 (de) 20,21-dinoreburnaminderivate, substituiert in position 15, verfahren zu deren herstellung und die auf diese weise erhaltenen zwischenverbindungen, deren anwendung als arzneimittel und diese enthaltende zusammensetzungen
DE69102310D1 (de) Pyridylsulfonylharnstoff- und Pyridylsulfonylthioharnstoff-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen.
ES2105569T3 (es) Nuevos analogos de metabolitos de acidos grasos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee