ATE132187T1 - Fledermausspeichel-plasminogenaktivator vpa-alpha 1 - Google Patents

Fledermausspeichel-plasminogenaktivator vpa-alpha 1

Info

Publication number
ATE132187T1
ATE132187T1 AT90250043T AT90250043T ATE132187T1 AT E132187 T1 ATE132187 T1 AT E132187T1 AT 90250043 T AT90250043 T AT 90250043T AT 90250043 T AT90250043 T AT 90250043T AT E132187 T1 ATE132187 T1 AT E132187T1
Authority
AT
Austria
Prior art keywords
vpa
alpha
plasminogen activator
bat saliva
saliva plasminogen
Prior art date
Application number
AT90250043T
Other languages
English (en)
Inventor
Berthold Baldus
Peter Donner
Wolf-Dieter Schleuning
Alejandro Alagon
Werner Boidol
Joern Reiner Kraetzschmar
Bernhard Jacques Haendler
Gernot Langer
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE3904580A external-priority patent/DE3904580A1/de
Priority claimed from DE19893917949 external-priority patent/DE3917949A1/de
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of ATE132187T1 publication Critical patent/ATE132187T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT90250043T 1989-02-13 1990-02-13 Fledermausspeichel-plasminogenaktivator vpa-alpha 1 ATE132187T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3904580A DE3904580A1 (de) 1989-02-13 1989-02-13 Neues thrombolytikum
DE19893917949 DE3917949A1 (de) 1989-05-30 1989-05-30 Neues thrombolytikum

Publications (1)

Publication Number Publication Date
ATE132187T1 true ATE132187T1 (de) 1996-01-15

Family

ID=25877826

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90250043T ATE132187T1 (de) 1989-02-13 1990-02-13 Fledermausspeichel-plasminogenaktivator vpa-alpha 1

Country Status (16)

Country Link
EP (1) EP0383417B1 (de)
JP (1) JP2904918B2 (de)
AT (1) ATE132187T1 (de)
AU (1) AU642404B2 (de)
BR (1) BR9007115A (de)
CA (1) CA2046632C (de)
DE (1) DE69024382T2 (de)
DK (1) DK0383417T3 (de)
ES (1) ES2085326T3 (de)
FI (1) FI103577B1 (de)
GR (1) GR3019328T3 (de)
HU (1) HU217219B (de)
IE (1) IE73229B1 (de)
NO (1) NO308708B1 (de)
UA (1) UA34415C2 (de)
WO (1) WO1990009438A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI100403B (fi) * 1988-07-20 1997-11-28 Schering Ag Menetelmä glykosyloitujen tai glykosyloimattomien vampyyrilepakon sylj en plasminogeeniaktivaattoreiden valmistamiseksi
DE3943241A1 (de) * 1989-12-22 1991-06-27 Schering Ag Thrombolytisch wirkendes kombinationspraeparat
DE4442665A1 (de) * 1994-11-30 1996-06-05 Gruenenthal Gmbh Chimäre Proteine mit fibrinolytischen und thrombinhemmenden Eigenschaften
US5731186A (en) * 1996-02-05 1998-03-24 Schering Aktiengesellschaft Method for the production of rDSPA α1
DE10016139A1 (de) * 2000-03-27 2001-10-18 Schleuning Wolf Dieter Verfahren zur Bestimmung von löslichem Fibrin
DE10153601A1 (de) 2001-11-02 2003-05-22 Paion Gmbh DSPA zur Behandlung von Schlaganfall
ES2297423T3 (es) * 2003-05-21 2008-05-01 Ares Trading S.A. Metodo de analisis cromatografico de una solucion proteica.
DE10342518A1 (de) * 2003-09-12 2005-05-12 Paion Gmbh Plasminogen-Aktivatoren mit verringerter Lysin-Bindungskapazität
GB0321997D0 (en) 2003-09-19 2003-10-22 Novartis Ag Organic compound
WO2007134617A1 (en) * 2006-05-19 2007-11-29 Paion Deutschland Gmbh Use of desmodus salivary plasminogen activator (dspa) for treating venous thromboembolism
CA2669181A1 (en) 2006-11-17 2008-05-22 Novartis Ag Lingo binding molecules and pharmaceutical use thereof
JP5698534B2 (ja) 2007-11-02 2015-04-08 ノバルティス アーゲー 改良されたｎｏｇｏ−ａ結合分子およびその医薬的使用
WO2011107299A2 (en) 2010-04-16 2011-09-09 Paion Deutschland Gmbh Method for the manufacture of recombinant dspa alpha1
MX2022004737A (es) 2019-10-24 2023-02-16 Novago Therapeutics Ag Anticuerpos anti-nogo-a novedosos.
WO2026041734A1 (en) 2024-08-22 2026-02-26 Novago Therapeutics Ag Methods for treating neurological disorders using anti-nogo-a antibodies

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI100403B (fi) * 1988-07-20 1997-11-28 Schering Ag Menetelmä glykosyloitujen tai glykosyloimattomien vampyyrilepakon sylj en plasminogeeniaktivaattoreiden valmistamiseksi

Also Published As

Publication number Publication date
WO1990009438A1 (en) 1990-08-23
DE69024382T2 (de) 1996-08-14
JPH04504799A (ja) 1992-08-27
NO913129D0 (no) 1991-08-12
ES2085326T3 (es) 1996-06-01
CA2046632C (en) 1999-05-11
IE73229B1 (en) 1997-05-21
AU5080790A (en) 1990-09-05
EP0383417A1 (de) 1990-08-22
CA2046632A1 (en) 1990-08-14
DK0383417T3 (da) 1996-05-13
IE900506L (en) 1990-08-13
HU217219B (hu) 1999-12-28
JP2904918B2 (ja) 1999-06-14
EP0383417B1 (de) 1995-12-27
BR9007115A (pt) 1991-11-26
NO308708B1 (no) 2000-10-16
HU902004D0 (en) 1991-11-28
FI913818A0 (fi) 1991-08-12
UA34415C2 (uk) 2001-03-15
GR3019328T3 (en) 1996-06-30
FI103577B (fi) 1999-07-30
NO913129L (no) 1991-10-11
FI103577B1 (fi) 1999-07-30
DE69024382D1 (de) 1996-02-08
AU642404B2 (en) 1993-10-21
HUT59724A (en) 1992-06-29

Similar Documents

Publication Publication Date Title
ATE132187T1 (de) Fledermausspeichel-plasminogenaktivator vpa-alpha 1
ATE113846T1 (de) Therapeutische zusammensetzungen für die behandlung von myocard-infarkten.
NO885109D0 (no) FremgangsmŸte og middel for Ÿ forhindre blodpropp.
FR13C0021I2 (fr) Conjugates d'exendin-4 et leur utilisation medicale
BG60253B1 (bg) Човешки тъканен плазминогенен активатор
DE68929551D1 (de) Menschliche DNase
EP0787802A3 (de)
DK0786257T3 (da) Glycolyseringsvarianter af vævsplasminogenaktivator med forbedrede terapeutiske egenskaber
DK31088D0 (da) Blodkoaguleringsnedsaettende peptidderivater
IT1142032B (it) Preparato che favorisce la coagulazione del sangue a base di proteine umani, nonche' procedimento per la preparazione
IT1238825B (it) Dispositivo per la correzione chirurgica dell'ametropia.
IT8868118A0 (it) Composizione e procedimento per il trattamento e la cura dei capelli
PH25503A (en) Method of medical treatment
IT9041503A0 (it) Dispositivo per la cura chirurgica dell'ametropia
ATE120645T1 (de) Verfahren und therapeutische zubereitungen für die behandlung von gerinnungsstörungen.
DE3780357D1 (de) Plasminogen-aktivator und thrombolytische zusammensetzung.
FI880891A7 (fi) Humaanikudoksen plasminogeenin rekombinanttiaktivaattorin koostumus.
IT8919215A0 (it) Dispositivo per la cura chirurgica dell'ametropia.
DE68914886D1 (de) Mittel zur Behandlung von Raynaud's Krankheit.
NO880831D0 (no) Rekombinant human vevsplasminogen-aktivatorblanding.
ATE337745T1 (de) Behandlungsinstrument für die medizinische oder zahnmedizinische behandlung von kindern
DE59611380D1 (de) Behandlungsinstrument für die medizinische oder zahnmedizinische behandlung von kindern
DE3765614D1 (de) Augenchirurgisches instrument zum absaugen und spuelen.
ATE274328T1 (de) Behandlung und fixierung von gewebe

Legal Events

Date Code Title Description
EELA Cancelled due to lapse of time