ATE132197T1 - Monoklonale antikörper - Google Patents

Monoklonale antikörper

Info

Publication number
ATE132197T1
ATE132197T1 AT89104494T AT89104494T ATE132197T1 AT E132197 T1 ATE132197 T1 AT E132197T1 AT 89104494 T AT89104494 T AT 89104494T AT 89104494 T AT89104494 T AT 89104494T AT E132197 T1 ATE132197 T1 AT E132197T1
Authority
AT
Austria
Prior art keywords
antibodies
fragments
monoclonal antibodies
cell surface
human cell
Prior art date
Application number
AT89104494T
Other languages
English (en)
Inventor
Manfred Dr Brockhaus
Hansruedi Dr Loetscher
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE132197T1 publication Critical patent/ATE132197T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT89104494T 1988-03-17 1989-03-14 Monoklonale antikörper ATE132197T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888806339A GB8806339D0 (en) 1988-03-17 1988-03-17 Monoclonal antibodies

Publications (1)

Publication Number Publication Date
ATE132197T1 true ATE132197T1 (de) 1996-01-15

Family

ID=10633598

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89104494T ATE132197T1 (de) 1988-03-17 1989-03-14 Monoklonale antikörper

Country Status (10)

Country Link
EP (1) EP0334165B1 (de)
JP (1) JPH02154695A (de)
AT (1) ATE132197T1 (de)
AU (1) AU618326B2 (de)
DE (1) DE68925226T2 (de)
DK (1) DK113389A (de)
GB (1) GB8806339D0 (de)
IE (1) IE890853L (de)
NZ (1) NZ228296A (de)
ZA (1) ZA891861B (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL83878A (en) * 1987-09-13 1995-07-31 Yeda Res & Dev Soluble protein corresponding to tnf inhibitory protein its preparation and pharmaceutical compositions containing it
US5359037A (en) * 1988-09-12 1994-10-25 Yeda Research And Development Co. Ltd. Antibodies to TNF binding protein I
IL94039A (en) * 1989-08-06 2006-09-05 Yeda Res & Dev Antibodies to tbp - 1 and their use
US6221675B1 (en) 1989-04-21 2001-04-24 Amgen, Inc. TNF receptors, TNF binding proteins and DNAs coding for them
US7264944B1 (en) 1989-04-21 2007-09-04 Amgen Inc. TNF receptors, TNF binding proteins and DNAs coding for them
ATE289350T1 (de) 1989-04-21 2005-03-15 Amgen Inc Tnf-rezeptor, tnf bindende proteine und dafür kodierende dnas
US6232446B1 (en) * 1989-05-18 2001-05-15 Yeda Research And Development Co. Ltd. TNF ligands
ATE119942T1 (de) * 1989-05-18 1995-04-15 Yeda Res & Dev Tumor-nekrosefaktor-bindungsprotein ii, seine reinigung und spezifische antikörper.
US6143866A (en) * 1989-07-18 2000-11-07 Amgen, Inc. Tumor necrosis factor (TNF) inhibitor and method for obtaining the same
IL95031A (en) 1989-07-18 2007-03-08 Amgen Inc Method for the production of a human recombinant tumor necrosis factor inhibitor
US20030225254A1 (en) 1989-08-07 2003-12-04 Rathjen Deborah Ann Tumour necrosis factor binding ligands
JP3443119B2 (ja) 1989-08-07 2003-09-02 ペプテック リミテッド 腫瘍壊死因子結合リガンド
EP0491878B1 (de) * 1989-08-16 1997-02-19 Chiron Corporation Zusammensetzungen zur hemmung der bildung von proteinhormon und deren verwendungen
NZ235148A (en) 1989-09-05 1991-12-23 Immunex Corp Tumour necrosis factor receptor protein and dna sequences
US5395760A (en) * 1989-09-05 1995-03-07 Immunex Corporation DNA encoding tumor necrosis factor-α and -β receptors
AU630497B2 (en) * 1989-09-05 1992-10-29 Immunex Corporation Tumor necrosis factor-alpha and -beta receptors
DE10399023I2 (de) 1989-09-12 2006-11-23 Ahp Mfg B V TFN-bindende Proteine
DE4006269A1 (de) * 1990-02-28 1991-08-29 Max Planck Gesellschaft Antikoerper gegen den tumor-nekrosefaktor-rezeptor
US6552170B1 (en) 1990-04-06 2003-04-22 Amgen Inc. PEGylation reagents and compounds formed therewith
ATE198770T1 (de) * 1991-06-19 2001-02-15 Boehringer Ingelheim Int Monoklonale antikörper gegen das humane tnf- bindende protein i (tnf-bp i)
US5582998A (en) * 1991-06-19 1996-12-10 Boehringer Ingelheim International Gmbh Monoclonal antibodies against human TNF-binding protein I (TNF-BP I) and immunoassays therefor
EP0585705B1 (de) * 1992-08-28 1998-11-04 Bayer Corporation Verwendung von monoklonalen Anti-TNF-Antikörpern für die Behandlung von bakteriellen Meningitiden
IT1270943B (it) * 1993-05-14 1997-05-26 Mini Ricerca Scient Tecnolog Anticorpi monoclonali anti-recettore di tipo i tnf alfa, procedimento per la produzione e loro usi
EP0791360A3 (de) * 1996-02-29 1997-09-24 Bayer Corporation Behandlung von septischem Schock mit Anti-TNF Antikörper
TW555765B (en) 1996-07-09 2003-10-01 Amgen Inc Low molecular weight soluble tumor necrosis factor type-I and type-II proteins
ATE247974T1 (de) 1996-12-06 2003-09-15 Amgen Inc Kombinationtherapie mit einem tnf-bindendem protein zür behandlung von durch tnf verursachten erkrangungen
US6660843B1 (en) 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
US9028822B2 (en) 2002-06-28 2015-05-12 Domantis Limited Antagonists against TNFR1 and methods of use therefor
US10988543B2 (en) 2015-11-11 2021-04-27 Opi Vi—Ip Holdco Llc Humanized anti-tumor necrosis factor alpha receptor 2 (anti-TNFR2) antibodies and methods of use thereof to elicit an immune response against a tumor

Also Published As

Publication number Publication date
JPH02154695A (ja) 1990-06-14
DE68925226T2 (de) 1996-05-15
AU3125289A (en) 1989-09-21
GB8806339D0 (en) 1988-04-13
ZA891861B (en) 1989-11-29
DE68925226D1 (de) 1996-02-08
EP0334165A2 (de) 1989-09-27
AU618326B2 (en) 1991-12-19
DK113389A (da) 1989-09-18
EP0334165A3 (en) 1990-05-16
EP0334165B1 (de) 1995-12-27
IE890853L (en) 1989-09-17
NZ228296A (en) 1992-01-29
DK113389D0 (da) 1989-03-08

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