ATE133494T1 - Verfahren zur verstärkung der chemilumineszenz von enzymgetriggerten 1,2-dioxetanen und seine verwendung - Google Patents

Verfahren zur verstärkung der chemilumineszenz von enzymgetriggerten 1,2-dioxetanen und seine verwendung

Info

Publication number: ATE133494T1
Authority: AT; Austria
Prior art keywords: triggered; enzyme; chemiluminescence; enhancement; dioxetans
Prior art date: 1991-07-31

Application number

AT92916112T

Other languages

English (en)

Inventor

Lynne Elizabeth Anderson

Robert Kenneth Kobos

Shay Evan Queen Lane Polsky

Original Assignee

Du Pont

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-07-31

Filing date

1992-07-28

Publication date

1996-02-15

1992-07-28 Application filed by Du Pont filed Critical Du Pont

1996-02-15 Application granted granted Critical

1996-02-15 Publication of ATE133494T1 publication Critical patent/ATE133494T1/de

Links

238000000034 method Methods 0.000 title abstract 3
BVTJGGGYKAMDBN-UHFFFAOYSA-N Dioxetane Chemical class C1COO1 BVTJGGGYKAMDBN-UHFFFAOYSA-N 0.000 abstract 2
102000004190 Enzymes Human genes 0.000 abstract 2
108090000790 Enzymes Proteins 0.000 abstract 2
238000001035 drying Methods 0.000 abstract 2
239000007787 solid Substances 0.000 abstract 2
230000001960 triggered effect Effects 0.000 abstract 2
238000001514 detection method Methods 0.000 abstract 1
238000010438 heat treatment Methods 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive

Landscapes

Health & Medical Sciences (AREA)
Immunology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Food Science & Technology (AREA)
General Physics & Mathematics (AREA)
Cell Biology (AREA)
Biotechnology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Pathology (AREA)
Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

AT92916112T 1991-07-31 1992-07-28 Verfahren zur verstärkung der chemilumineszenz von enzymgetriggerten 1,2-dioxetanen und seine verwendung ATE133494T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US73840891A	1991-07-31	1991-07-31

Publications (1)

Publication Number	Publication Date
ATE133494T1 true ATE133494T1 (de)	1996-02-15

Family

ID=24967884

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92916112T ATE133494T1 (de)	1991-07-31	1992-07-28	Verfahren zur verstärkung der chemilumineszenz von enzymgetriggerten 1,2-dioxetanen und seine verwendung

Country Status (16)

Country	Link
US (1)	US5270164A (de)
EP (1)	EP0597916B1 (de)
JP (1)	JP3299269B2 (de)
AT (1)	ATE133494T1 (de)
AU (1)	AU2394192A (de)
CA (1)	CA2114522A1 (de)
DE (1)	DE69207911T2 (de)
DK (1)	DK0597916T3 (de)
ES (1)	ES2084368T3 (de)
GR (1)	GR3019432T3 (de)
HK (1)	HK146996A (de)
IE (1)	IE74889B1 (de)
IL (1)	IL102523A0 (de)
LT (1)	LTIP860A (de)
MX (1)	MX9204448A (de)
WO (1)	WO1993003380A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK0614530T3 (da) *	1991-11-15	1998-09-28	Cornell Res Foundation Inc	Indirekte immunassay for dioxinlignende forbindelser
FR2710655B1 (fr) *	1993-09-29	1995-12-01	Inst Nat Rech Securite	Procédé pour effectuer un test biologique destiné à identifier et à doser des gènes, des protéines et autres molécules.
US5846753A (en) *	1995-05-30	1998-12-08	The United States Of America As Represented By The Secretary Of The Army	Chemiluminescence-based method for rapid and sensitive in-situ detection of organophosphorus compounds and metal ions
US5783381A (en) *	1995-10-19	1998-07-21	Tropix, Inc.	Chemiluminescent 1,2-dioxetanes
ATE510209T1 (de) *	1997-10-09	2011-06-15	Carmel Diagnostics Ltd	Verfahren und vorrichtung zur messung von lipidperoxidation in biologischen flüssigkeiten und stuffsuspensionen
US6867005B2 (en) *	2001-10-24	2005-03-15	Beckman Coulter, Inc.	Method and apparatus for increasing the dynamic range and accuracy of binding assays
US7166478B2 (en) *	2002-03-12	2007-01-23	Enzo Life Sciences, Inc., C/O Enzo Biochem, Inc.	Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses
US7767404B2 (en) *	2005-08-16	2010-08-03	Chipotle Business Group, Inc.	Apparatus and method for single-step immunosorbent assay for single and multiple analytes
US8735142B2 (en) *	2005-08-16	2014-05-27	Chipotle Business Group, Inc.	Systems and methods for immunosorbent assays for single and multiple analytes
US10914737B2 (en) *	2013-04-24	2021-02-09	Euroimmun Medizinische Labordiagnostika Ag	Method for automated evaluation of incubated immunoblot strips

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL8201492A (nl) *	1982-04-07	1983-11-01	Rijksuniversiteit	Werkwijze ter bereiding van een op de 4-plaats equatoriaal gesubstitueerde symmetrisch-polycycloethyleenverbinding; op de 4-plaats equatoriaal gesubstitueerde symmetrisch-polycycloethyleenverbinding alsmede een op basis van de verbinding bereid thermochemiluminescerend merkmateriaal of thermochemiluminescerend sondeermateriaal.
US4778767A (en) *	1984-12-17	1988-10-18	Akzo N.V.	Solid phase immunoassay using immunoreagents immobilized on inert synthetic resin surfaces
US4857652A (en) *	1986-07-17	1989-08-15	Board Of Governors Of Wayne State University	Chemiluminescent 1,2-dioxetane compounds
US4959182A (en) *	1986-07-17	1990-09-25	Board Of Governors Of Wayne State University	Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes
US4956477A (en) *	1987-12-31	1990-09-11	Tropix, Inc.	Synthesis of 1,2-dioxetanes
EP0275260B1 (de) *	1986-07-24	1993-11-18	Tropix, Inc.	Verfahren zum nachweis einer verbindung unter verwendung des enzymatisch induzierten zerfalls von dioxethanen
EP0261719A3 (de) *	1986-09-23	1990-10-10	Akzo N.V.	Thermochemischlumineszierende Komplexe von Cyclodextrinen
US5089423A (en) *	1987-05-06	1992-02-18	Cyberfluor Inc.	Immunoassay methods and reagents and methods for producing the latter
JP2583327B2 (ja) *	1987-12-31	1997-02-19	トロピックス・インコーポレイテッド	分析で使用するジオキセタン
US4952707A (en) *	1988-06-30	1990-08-28	Tropix, Inc.	Enzymatically-cleavable chemiluminescent fused polycyclic ring-containing 1,2-dioxetanes
US4948975A (en) *	1988-09-08	1990-08-14	The United States Of America As Represented By The Secretary Of The Air Force	Quantitative luminescence imaging system

1992
- 1992-07-16 IL IL102523A patent/IL102523A0/xx unknown
- 1992-07-28 DE DE69207911T patent/DE69207911T2/de not_active Expired - Lifetime
- 1992-07-28 AT AT92916112T patent/ATE133494T1/de active
- 1992-07-28 AU AU23941/92A patent/AU2394192A/en not_active Abandoned
- 1992-07-28 CA CA002114522A patent/CA2114522A1/en not_active Abandoned
- 1992-07-28 WO PCT/US1992/006115 patent/WO1993003380A1/en not_active Ceased
- 1992-07-28 DK DK92916112.3T patent/DK0597916T3/da active
- 1992-07-28 EP EP92916112A patent/EP0597916B1/de not_active Expired - Lifetime
- 1992-07-28 ES ES92916112T patent/ES2084368T3/es not_active Expired - Lifetime
- 1992-07-28 JP JP50361993A patent/JP3299269B2/ja not_active Expired - Lifetime
- 1992-07-29 IE IE922462A patent/IE74889B1/en not_active IP Right Cessation
- 1992-07-30 MX MX9204448A patent/MX9204448A/es unknown
1993
- 1993-03-01 US US08/024,700 patent/US5270164A/en not_active Expired - Lifetime
- 1993-08-16 LT LTIP860A patent/LTIP860A/xx not_active Application Discontinuation
1996
- 1996-03-27 GR GR960400818T patent/GR3019432T3/el unknown
- 1996-08-01 HK HK146996A patent/HK146996A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
IE74889B1 (en)	1997-08-13
DK0597916T3 (da)	1996-02-26
US5270164A (en)	1993-12-14
GR3019432T3 (en)	1996-06-30
MX9204448A (es)	1993-05-01
JP3299269B2 (ja)	2002-07-08
EP0597916B1 (de)	1996-01-24
EP0597916A1 (de)	1994-05-25
WO1993003380A1 (en)	1993-02-18
DE69207911T2 (de)	1996-07-04
JPH06509648A (ja)	1994-10-27
DE69207911D1 (de)	1996-03-07
AU2394192A (en)	1993-03-02
IE922462A1 (en)	1993-02-10
IL102523A0 (en)	1993-01-14
LTIP860A (en)	1995-03-27
CA2114522A1 (en)	1993-02-18
HK146996A (en)	1996-08-09
ES2084368T3 (es)	1996-05-01

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