ATE133959T1 - Tetrapeptidderivate und deren analoga - Google Patents
Tetrapeptidderivate und deren analogaInfo
- Publication number
- ATE133959T1 ATE133959T1 AT92901228T AT92901228T ATE133959T1 AT E133959 T1 ATE133959 T1 AT E133959T1 AT 92901228 T AT92901228 T AT 92901228T AT 92901228 T AT92901228 T AT 92901228T AT E133959 T1 ATE133959 T1 AT E133959T1
- Authority
- AT
- Austria
- Prior art keywords
- gastrin
- pct
- cholecystokinin
- tetrapeptide
- sec
- Prior art date
Links
- AOXOCDRNSPFDPE-UKEONUMOSA-N chembl413654 Chemical compound C([C@H](C(=O)NCC(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@H](CCSC)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H]1N(CCC1)C(=O)CNC(=O)[C@@H](N)CCC(O)=O)C1=CC=C(O)C=C1 AOXOCDRNSPFDPE-UKEONUMOSA-N 0.000 abstract 5
- 102100021022 Gastrin Human genes 0.000 abstract 4
- 108010052343 Gastrins Proteins 0.000 abstract 4
- 102100025841 Cholecystokinin Human genes 0.000 abstract 1
- 101800001982 Cholecystokinin Proteins 0.000 abstract 1
- 108010089448 Cholecystokinin B Receptor Proteins 0.000 abstract 1
- 102000004859 Cholecystokinin Receptors Human genes 0.000 abstract 1
- 108090001085 Cholecystokinin Receptors Proteins 0.000 abstract 1
- 102000052874 Gastrin receptors Human genes 0.000 abstract 1
- 108010012944 Tetragastrin Proteins 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 210000004899 c-terminal region Anatomy 0.000 abstract 1
- 229940107137 cholecystokinin Drugs 0.000 abstract 1
- 239000003753 cholecystokinin receptor stimulating agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000001360 methionine group Chemical group N[C@@H](CCSC)C(=O)* 0.000 abstract 1
- 239000004031 partial agonist Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- IZTQOLKUZKXIRV-YRVFCXMDSA-N sincalide Chemical compound C([C@@H](C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@@H](N)CC(O)=O)C1=CC=C(OS(O)(=O)=O)C=C1 IZTQOLKUZKXIRV-YRVFCXMDSA-N 0.000 abstract 1
- RGYLYUZOGHTBRF-BIHRQFPBSA-N tetragastrin Chemical compound C([C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CC=1C2=CC=CC=C2NC=1)CCSC)C(N)=O)C1=CC=CC=C1 RGYLYUZOGHTBRF-BIHRQFPBSA-N 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/595—Gastrins; Cholecystokinins [CCK]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909027286A GB9027286D0 (en) | 1990-12-17 | 1990-12-17 | Tetrapeptide derivatives and analogues |
| GB919123231A GB9123231D0 (en) | 1990-12-17 | 1991-11-01 | Tetrapeptide derivatives and analogues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE133959T1 true ATE133959T1 (de) | 1996-02-15 |
Family
ID=26298121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92901228T ATE133959T1 (de) | 1990-12-17 | 1991-12-17 | Tetrapeptidderivate und deren analoga |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5486597A (de) |
| EP (1) | EP0563132B1 (de) |
| AT (1) | ATE133959T1 (de) |
| AU (1) | AU9057791A (de) |
| DE (1) | DE69117070D1 (de) |
| IE (1) | IE914334A1 (de) |
| WO (1) | WO1992011284A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994009031A1 (en) * | 1992-10-19 | 1994-04-28 | Warner-Lambert Company | Analogues of cholecystokinin (30-33) containing an alpha-substituted aminoacid |
| AU6659298A (en) | 1997-02-18 | 1998-09-08 | Thomas Jefferson University | Compositions that bind to pancreatic cancer cells and methods of using the same |
| EA002724B1 (ru) * | 1997-10-10 | 2002-08-29 | Авентис Фармасьютикалз Продактс Инк. | Способ получения азациклоалкилалканоилпсевдотетрапептидов |
| CA3011538A1 (en) | 2016-01-18 | 2017-07-27 | Arisan Therapeutics | Adamantane derivatives for the treatment of filovirus infection |
| WO2019018185A1 (en) | 2017-07-15 | 2019-01-24 | Arisan Therapeutics Inc. | ENANTIOMERICALLY PURE ADAMATANE DERIVATIVES FOR THE TREATMENT OF FILOVIRUS INFECTIONS |
| CN107759477A (zh) * | 2017-11-20 | 2018-03-06 | 阿里化学(常州)有限公司 | 一种对硝基苯乙胺盐酸盐的生产制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR890100827A (el) * | 1988-12-21 | 1991-03-15 | Abbott Lab | Μέ?οδος παραγωγής παραγώγων τετραπεπτιδίων ως ανταγωνιστών CCK. |
| IE902238A1 (en) * | 1989-06-30 | 1991-01-16 | Abbott Lab | Tetrapeptide type-b cck receptor ligands |
-
1991
- 1991-12-12 IE IE433491A patent/IE914334A1/en unknown
- 1991-12-17 AU AU90577/91A patent/AU9057791A/en not_active Abandoned
- 1991-12-17 EP EP92901228A patent/EP0563132B1/de not_active Expired - Lifetime
- 1991-12-17 DE DE69117070T patent/DE69117070D1/de not_active Expired - Lifetime
- 1991-12-17 WO PCT/GB1991/002249 patent/WO1992011284A1/en not_active Ceased
- 1991-12-17 AT AT92901228T patent/ATE133959T1/de not_active IP Right Cessation
- 1991-12-17 US US08/075,528 patent/US5486597A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0563132B1 (de) | 1996-02-07 |
| WO1992011284A1 (en) | 1992-07-09 |
| US5486597A (en) | 1996-01-23 |
| EP0563132A1 (de) | 1993-10-06 |
| AU9057791A (en) | 1992-07-22 |
| IE914334A1 (en) | 1992-06-17 |
| DE69117070D1 (de) | 1996-03-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |