ATE134873T1 - Stabile zusammensetzungen für parenterale verabrechung und ihre verwendung - Google Patents

Stabile zusammensetzungen für parenterale verabrechung und ihre verwendung

Info

Publication number: ATE134873T1
Authority: AT; Austria
Prior art keywords: compounds; parenteral administration; lambda; warm; alpha
Prior art date: 1991-07-23

Application number

AT92107277T

Other languages

English (en)

Inventor

Susan Mancini Cady

William David Steber

Phillip Wayne Hayes

Mary Ehlers Doscher

Kurt Allen Schwinghammer

Original Assignee

American Cyanamid Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-07-23

Filing date

1992-04-29

Publication date

1996-03-15

1992-04-29 Application filed by American Cyanamid Co filed Critical American Cyanamid Co

1996-03-15 Application granted granted Critical

1996-03-15 Publication of ATE134873T1 publication Critical patent/ATE134873T1/de

Links

239000000203 mixture Substances 0.000 title abstract 5
238000007911 parenteral administration Methods 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 abstract 4
241001465754 Metazoa Species 0.000 abstract 2
YNFMRVVYUVPIAN-UHFFFAOYSA-N nemadectin alpha Natural products C1C(O)C(C)C(C(C)=CC(C)C)OC11OC(CC=C(C)CC(C)C=CC=C2C3(C(C(=O)O4)C=C(C)C(O)C3OC2)O)CC4C1 YNFMRVVYUVPIAN-UHFFFAOYSA-N 0.000 abstract 2
241000238421 Arthropoda Species 0.000 abstract 1
241000244206 Nematoda Species 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
239000003963 antioxidant agent Substances 0.000 abstract 1
230000003078 antioxidant effect Effects 0.000 abstract 1
RRZXIRBKKLTSOM-XPNPUAGNSA-N avermectin B1a Chemical class C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 0.000 abstract 1
239000008280 blood Substances 0.000 abstract 1
210000004369 blood Anatomy 0.000 abstract 1
235000014113 dietary fatty acids Nutrition 0.000 abstract 1
229930195729 fatty acid Natural products 0.000 abstract 1
239000000194 fatty acid Substances 0.000 abstract 1
150000004665 fatty acids Chemical class 0.000 abstract 1
244000000013 helminth Species 0.000 abstract 1
208000015181 infectious disease Diseases 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000004005 microsphere Substances 0.000 abstract 1
FXWHFKOXMBTCMP-WMEDONTMSA-N milbemycin Chemical class COC1C2OCC3=C/C=C/C(C)CC(=CCC4CC(CC5(O4)OC(C)C(C)C(OC(=O)C(C)CC(C)C)C5O)OC(=O)C(C=C1C)C23O)C FXWHFKOXMBTCMP-WMEDONTMSA-N 0.000 abstract 1
YNFMRVVYUVPIAN-AQUURSMBSA-N nemadectin Chemical compound C1[C@H](O)[C@H](C)[C@@H](C(/C)=C/C(C)C)O[C@]11O[C@H](C\C=C(C)\C[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 YNFMRVVYUVPIAN-AQUURSMBSA-N 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Tropical Medicine & Parasitology (AREA)
Biophysics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

AT92107277T 1991-07-23 1992-04-29 Stabile zusammensetzungen für parenterale verabrechung und ihre verwendung ATE134873T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US73443091A	1991-07-23	1991-07-23

Publications (1)

Publication Number	Publication Date
ATE134873T1 true ATE134873T1 (de)	1996-03-15

Family

ID=24951666

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92107277T ATE134873T1 (de)	1991-07-23	1992-04-29	Stabile zusammensetzungen für parenterale verabrechung und ihre verwendung

Country Status (20)

Country	Link
US (1)	US6340671B1 (de)
EP (1)	EP0525307B1 (de)
JP (1)	JP3470904B2 (de)
KR (1)	KR100235550B1 (de)
CN (1)	CN1046852C (de)
AT (1)	ATE134873T1 (de)
AU (1)	AU651229B2 (de)
BR (1)	BR9202771A (de)
CA (1)	CA2074348C (de)
DE (1)	DE69208765T2 (de)
DK (1)	DK0525307T3 (de)
ES (1)	ES2086022T3 (de)
GR (1)	GR3019234T3 (de)
HU (1)	HU220595B1 (de)
IE (1)	IE74401B1 (de)
IL (1)	IL102567A (de)
MX (1)	MX9204135A (de)
NZ (1)	NZ243619A (de)
TW (1)	TW201696B (de)
ZA (1)	ZA925522B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5733566A (en) *	1990-05-15	1998-03-31	Alkermes Controlled Therapeutics Inc. Ii	Controlled release of antiparasitic agents in animals
US5686092A (en) *	1992-11-24	1997-11-11	Alkermes Controlled Therapeutics Inc. Ii	Growth promoters for animals
DE4308282C2 (de) *	1993-03-16	1994-12-22	Beiersdorf Ag	Vorzugsweise in Form von Mikrosphärulen vorliegende galenische Matrices
DE19613972A1 (de) *	1996-04-09	1997-10-16	Bayer Ag	Injektionsformulierungen von Avermectinen und Milbemycinen auf Basis von Rizinusöl
DE19638045A1 (de) *	1996-09-18	1998-03-19	Bayer Ag	Injektionsformulierungen von Avermectinen und Milbemycinen
KR20020011985A (ko) *	1999-05-07	2002-02-09	파르마솔 게엠베하	액상 및 고체상 지질 혼합물에 기초한 지질입자들 및 그의제조방법
CA2369594A1 (en) *	1999-05-07	2000-11-16	Pharmasol Gmbh	Lipid particles on the basis of mixtures of liquid and solid lipids and method for producing same
ATE392887T1 (de) *	2000-10-10	2008-05-15	Wyeth Corp	Stabilisierte arzneizusammensetzungen zur parenteralen vearbreichung
FR2852843B1 (fr)	2003-03-24	2008-05-23	Karim Ioualalen	Systeme galenique permettant le masquage du gout
NZ534939A (en) *	2004-08-26	2007-04-27	Bomac Research Ltd	Injectable formulation comprising an anthelmintic compound with complexing compound for improved solubility
MX2012004133A (es)	2009-10-07	2012-05-08	Wyeth Llc	Composiciones que comprenden adyuvante, macrolido y antigeno proteico y procedimientos de uso de las mismas.
ITUB20153652A1 (it) *	2015-09-16	2017-03-16	Fatro Spa	Microsfere contenenti lattoni macrociclici antielminitici
PL3609470T3 (pl)	2017-04-13	2024-04-15	Ceva Santé Animale	Implant do leczenia infekcji pasożytniczej
EP3927715A4 (de)	2019-02-21	2023-03-01	Chromadex, Inc.	Verwendung von nicotinamidribosid, nicotinsäureribosid, reduzierten nicotinylribosidverbindungen und nicotinylribosidverbindungen in formulierungen
CN113784702B (zh)	2019-05-03	2024-11-05	英特维特国际股份有限公司	可注射药物组合物及其用途
WO2021233967A1 (en)	2020-05-20	2021-11-25	Intervet International B.V.	Injectable pharmaceutical compositions and uses thereof
WO2022263505A1 (en) *	2021-06-16	2022-12-22	Société des Produits Nestlé S.A.	Methods of solid phase wax coating of an active ingredient
WO2024003291A1 (en)	2022-06-30	2024-01-04	Virbac	Deslorelin use in chemical castration of a non-human mammal related to pk/pd interaction
WO2025190964A1 (en)	2024-03-12	2025-09-18	Virbac	Parenteral modoflaner for the control of ectoparasites
US20260021076A1 (en)	2024-07-22	2026-01-22	Zoetis Services Llc	Isoxazoline and macrocyclic lactone microspheres
WO2026041795A1 (en)	2024-08-23	2026-02-26	Intervet International B.V.	Injectable veterinary composition for cattle

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3659022A (en) *	1967-11-13	1972-04-25	Upjohn Co	Methods of preventing impregnation
US4144352A (en) *	1977-12-19	1979-03-13	Merck & Co., Inc.	Milbemycin compounds as anthelmintic agents
US5106994A (en) *	1984-06-05	1992-04-21	American Cyanamid Company	Agents and method of production thereof
US5169956A (en) *	1984-06-05	1992-12-08	American Cyanamid Company	Macrolide antibiotic compounds
ATE74009T1 (de) *	1986-08-11	1992-04-15	American Cyanamid Co	Zusammensetzungen zur parenteralen verabreichung und deren verwendung.
GB8803836D0 (en) *	1988-02-18	1988-03-16	Glaxo Group Ltd	Compositions
DK0385106T3 (da) *	1989-02-28	1994-04-11	American Cyanamid Co	Bolus med forhalet frigivelse effektiv til forlænget prævention eller behandling af eller kontrol med nematode-, mide- og endo- og ektoparasitiske infektioner hos drøvtyggere
US5213810A (en) *	1990-03-30	1993-05-25	American Cyanamid Company	Stable compositions for parenteral administration and method of making same
US5192546A (en) *	1991-01-15	1993-03-09	Mycogen Corporation	Synergistic pesticidal compositions
US5346698A (en) *	1991-01-15	1994-09-13	Mycogen Corporation	Synergistic pesticidal compositions
US5185108A (en) *	1991-07-10	1993-02-09	The B. F. Goodrich Company	Method for producing wax microspheres
JP4654917B2 (ja)	2006-01-12	2011-03-23	日産自動車株式会社	車体後部構造

1992
- 1992-04-29 EP EP92107277A patent/EP0525307B1/de not_active Expired - Lifetime
- 1992-04-29 DK DK92107277.3T patent/DK0525307T3/da active
- 1992-04-29 ES ES92107277T patent/ES2086022T3/es not_active Expired - Lifetime
- 1992-04-29 AT AT92107277T patent/ATE134873T1/de active
- 1992-04-29 DE DE69208765T patent/DE69208765T2/de not_active Expired - Lifetime
- 1992-05-16 TW TW081103831A patent/TW201696B/zh not_active IP Right Cessation
- 1992-06-30 CN CN92105395A patent/CN1046852C/zh not_active Expired - Lifetime
- 1992-07-15 MX MX9204135A patent/MX9204135A/es unknown
- 1992-07-20 JP JP21325992A patent/JP3470904B2/ja not_active Expired - Lifetime
- 1992-07-20 BR BR929202771A patent/BR9202771A/pt not_active Application Discontinuation
- 1992-07-20 NZ NZ243619A patent/NZ243619A/en unknown
- 1992-07-21 CA CA002074348A patent/CA2074348C/en not_active Expired - Lifetime
- 1992-07-21 IL IL10256792A patent/IL102567A/en not_active IP Right Cessation
- 1992-07-22 ZA ZA925522A patent/ZA925522B/xx unknown
- 1992-07-22 IE IE922373A patent/IE74401B1/en not_active IP Right Cessation
- 1992-07-22 KR KR1019920013077A patent/KR100235550B1/ko not_active Expired - Lifetime
- 1992-07-22 HU HU9202404A patent/HU220595B1/hu unknown
- 1992-07-22 AU AU20472/92A patent/AU651229B2/en not_active Expired
1994
- 1994-06-22 US US08/263,574 patent/US6340671B1/en not_active Expired - Lifetime
1996
- 1996-03-07 GR GR950402159T patent/GR3019234T3/el unknown

Also Published As

Publication number	Publication date
EP0525307A1 (de)	1993-02-03
DK0525307T3 (da)	1996-04-01
JPH05194211A (ja)	1993-08-03
CA2074348A1 (en)	1993-01-24
HK1000005A1 (en)	1997-10-03
DE69208765D1 (de)	1996-04-11
HUT62454A (en)	1993-05-28
US6340671B1 (en)	2002-01-22
CN1068735A (zh)	1993-02-10
JP3470904B2 (ja)	2003-11-25
TW201696B (de)	1993-03-11
HU9202404D0 (en)	1992-10-28
HU220595B1 (hu)	2002-03-28
AU651229B2 (en)	1994-07-14
ES2086022T3 (es)	1996-06-16
BR9202771A (pt)	1993-03-23
CN1046852C (zh)	1999-12-01
KR100235550B1 (ko)	1999-12-15
AU2047292A (en)	1993-01-28
GR3019234T3 (en)	1996-06-30
IE74401B1 (en)	1997-07-30
IL102567A (en)	1996-10-31
KR930001904A (ko)	1993-02-22
CA2074348C (en)	2004-02-17
IE922373A1 (en)	1993-01-27
ZA925522B (en)	1993-04-28
EP0525307B1 (de)	1996-03-06
NZ243619A (en)	1994-12-22
MX9204135A (es)	1993-01-01
DE69208765T2 (de)	1996-09-26
IL102567A0 (en)	1993-01-14

Publication	Publication Date	Title
DE69208765D1 (de)	1996-04-11	Stabile Zusammensetzungen für parenterale Verabrechung und ihre Verwendung
CY1108145T1 (el)	2013-03-13	Σταθερες συνθεσεις για παρεντερικη χορηγηση
NO2011026I2 (no)	2012-06-11	Eribulin eller et farmasøytisk akseptabelt salt derav
PT96324A (pt)	1991-09-30	Processo para a preparacao de compostos peptidicos e de composicoes farmaceuticas que os contem
CY1110261T1 (el)	2012-05-23	Παραγωγα της κουμαρινης που χρησιμοποιουνται σαν αντιπηκτικα
BRPI0414514A (pt)	2006-11-07	uso de um composto, composto, e, composições farmacêuticas
KR950003289A (ko)	1995-02-16	5-ht1a 길항 활성을 지닌 2,3-디하이드로-1,4-벤조 디옥신-5-일-피페라진 유도체
KR890011902A (ko)	1989-08-23	디데옥시디데히드로카르보시클릭 뉴클레오시드
ATE427944T1 (de)	2009-04-15	Isoflavonderivative von tectoridin, deren herstellung und antivirale medikamente, die diese als wirksame bestandteile enthalten
KR900006330A (ko)	1990-05-07	피롤로[3,2-e]피라졸로[1,5-a]피리미딘 유도체 및 이를 함유하는 약제
KR890005088A (ko)	1989-05-11	4- 아미노피리딘 유도체 및 그의 산 부가염
ES2144154T3 (es)	2000-06-01	Derivados de eritromicina a 9-0-oxima dotados de actividad antibiotica.
CY1112057T1 (el)	2015-11-04	Θεραπευτικος παραγων για διαταραχη επαρκειας τροφης στο στομαχι
KR880012586A (ko)	1988-11-28	새로운 피리딜 및 피리미딜 유도체
HU9300202D0 (en)	1993-04-28	Benzo-pyrane derivatives, pharmaceutical preparatives containing them as active substance as well as method for producing them
KR900701795A (ko)	1990-12-04	티에노시클로 헵타피리다진 화합물과 그것의 의약용도
KR950701329A (ko)	1995-03-23	벤조티아졸술폰아미드 유도체, 그의 제조법 및 그 용도(Benzothiazolesulfornamide derivative, method for preparing the same, and use thereof)
ATE285771T1 (de)	2005-01-15	Diaminotrifluoromethylpyrimidinderivate enthaltende antikrebs-zusammensetzung
KR950703956A (ko)	1995-11-17	순환 장애 개선제[circulatory disturbance ameliorant]
ES2132283T3 (es)	1999-08-16	Derivados n-heteroaril sustituidos de propanamida utiles en el tratamiento de enfermedades cardiovasculares.
ES2179667T3 (es)	2003-01-16	Nuevas formulaciones inyectables que contienen ramoplanina.
IT8719093A0 (it)	1987-01-15	Derivati di esteri dell'acido immidazol-1-il-carbossilico, procedimenti per la loro preparazione e composizioni fungicide che contengono il derivato come componente attivo.
KR890016970A (ko)	1989-12-14	뇌 조직의 순환 혈액량 증가 조성물
CA2239053A1 (en)	1997-06-26	Diphenyl pyridyl ethane derivatives as pde iv inhibitors
KR920701163A (ko)	1992-08-11	퀴놀론 카르복실산 유도체