ATE134874T1 - Synoviale phospholipasen - Google Patents

Synoviale phospholipasen

Info

Publication number
ATE134874T1
ATE134874T1 AT88908529T AT88908529T ATE134874T1 AT E134874 T1 ATE134874 T1 AT E134874T1 AT 88908529 T AT88908529 T AT 88908529T AT 88908529 T AT88908529 T AT 88908529T AT E134874 T1 ATE134874 T1 AT E134874T1
Authority
AT
Austria
Prior art keywords
synovial
enzymes
phospholipases
spla2
antibodies
Prior art date
Application number
AT88908529T
Other languages
English (en)
Inventor
Lorin K Johnson
Jeffrey J Seilhamer
Waldemar Pruzanski
Peter Vadas
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/215,726 external-priority patent/US5019508A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE134874T1 publication Critical patent/ATE134874T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Pain & Pain Management (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT88908529T 1987-08-27 1988-08-23 Synoviale phospholipasen ATE134874T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8988387A 1987-08-27 1987-08-27
US07/215,726 US5019508A (en) 1987-08-27 1988-07-06 Synovial phospholipases
US23186588A 1988-08-16 1988-08-16

Publications (1)

Publication Number Publication Date
ATE134874T1 true ATE134874T1 (de) 1996-03-15

Family

ID=27376366

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88908529T ATE134874T1 (de) 1987-08-27 1988-08-23 Synoviale phospholipasen

Country Status (7)

Country Link
EP (1) EP0395653B1 (de)
JP (3) JP2872256B2 (de)
AT (1) ATE134874T1 (de)
AU (1) AU2424988A (de)
CA (1) CA1335800C (de)
DE (1) DE3855080T2 (de)
WO (1) WO1989001773A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989005851A1 (fr) * 1987-12-24 1989-06-29 Teijin Limited Nouvelle phospholipase humaine a2 et son fragment peptidique
IL101507A0 (en) * 1991-04-17 1992-12-30 Lilly Co Eli Compounds,vectors and methods for expressing human,cytosolic phospholipase a2
US6248553B1 (en) 1998-10-22 2001-06-19 Atairgin Technologies, Inc. Enzyme method for detecting lysophospholipids and phospholipids and for detecting and correlating conditions associated with altered levels of lysophospholipids
US6500633B1 (en) 2000-04-26 2002-12-31 Atairgin Technologies, Inc. Method of detecting carcinomas
EP1391207A1 (de) * 2001-04-24 2004-02-25 Luis Alberto Costa Verwendung einer phospholipase a2 zur herstellung von pharmazeutischen und/oder kosmetischen zusammensetzungen zur topischen und/oder systemischen behandlung und/oder prävention von krankheiten und/oder prozessen, die durch intra- und extrazelluläre erreger ausgelöst werden, die membran-phospholipide exprimieren
DE602004029559D1 (de) * 2003-03-04 2010-11-25 Nat Inst Of Advanced Ind Scien Aus koji-schimmelpilz stammende phospholipase a2
CA2777013A1 (en) 2009-10-16 2011-04-21 Mochida Pharmaceutical Co., Ltd. Marker associated with non-alcoholic steatohepatitis
US9486433B2 (en) 2012-10-12 2016-11-08 Mochida Pharmaceuticals Co. Ltd. Compositions and methods for treating non-alcoholic steatohepatitis
US10441560B2 (en) 2013-03-15 2019-10-15 Mochida Pharmaceutical Co., Ltd. Compositions and methods for treating non-alcoholic steatohepatitis
KR20150127599A (ko) 2013-03-15 2015-11-17 모치다 세이야쿠 가부시키가이샤 비알코올성 지방간염을 치료하기 위한 조성물 및 방법
EP2960252A1 (de) * 2014-06-26 2015-12-30 Institut Pasteur Phospholipase zur Behandlung von Immunosuppression

Also Published As

Publication number Publication date
EP0395653A1 (de) 1990-11-07
JPH04506447A (ja) 1992-11-12
EP0395653B1 (de) 1996-03-06
JP2872256B2 (ja) 1999-03-17
DE3855080T2 (de) 1996-07-18
DE3855080D1 (de) 1996-04-11
AU2424988A (en) 1989-03-31
CA1335800C (en) 1995-06-06
JPH09208492A (ja) 1997-08-12
JP2000102399A (ja) 2000-04-11
WO1989001773A1 (en) 1989-03-09
EP0395653A4 (en) 1991-12-04
JP3054092B2 (ja) 2000-06-19

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